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  1. Book: In memory of Professor Brian J. Chambers

    Chambers, Brian J. / Nicholson, Fiona A.

    (Soil use and management ; Volume 32, Supplement 1)

    2016  

    Author's details Edited by: Fiona A. Nicholson
    Series title Soil use and management ; Volume 32, Supplement 1
    Collection
    Language English
    Size 182 Seiten, Illustrationen
    Publisher Wiley Blackwell
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT019056146
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    Z 4234 (32,Suppl1) available for loan (reading room) Freihandmagazin (U1)

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  2. Article: Physiological JNK3 Concentrations Are Higher in Motor-related and Disease-implicated Brain Regions of C57BL6/J Mice.

    Godieva, Victoria / Sammoura, Ferass / Verrier Paz, Sebastian / Han, Yoonhee / Di Guida, Valentina / Rishel, Michael J / Richardson, Jason R / Chambers, Jeremy W

    bioRxiv : the preprint server for biology

    2024  

    Abstract: The c-Jun N-terminal kinase 3 (JNK3) is a stress-responsive protein kinase primarily expressed in the central nervous system (CNS). JNK3 exhibits nuanced neurological activities, such as roles in behavior, circadian rhythms, and neurotransmission, but ... ...

    Abstract The c-Jun N-terminal kinase 3 (JNK3) is a stress-responsive protein kinase primarily expressed in the central nervous system (CNS). JNK3 exhibits nuanced neurological activities, such as roles in behavior, circadian rhythms, and neurotransmission, but JNK3 is also implicated in cell death and neurodegeneration. Despite the critical role of JNK3 in neurophysiology and pathology, its localization in the brain is not fully understood due to a paucity of tools to distinguish JNK3 from other isoforms. While previous functional and histological studies suggest locales for JNK3 in the CNS, a comprehensive and higher resolution of JNK3 distribution and abundance remained elusive. Here, we sought to define the anatomical and cellular distribution of JNK3 in adult mouse brains. Data reveal the highest levels of JNK3 and pJNK3 were found in the cortex and the hippocampus. JNK3 possessed neuron-type selectivity as JNK3 was present in GABAergic, cholinergic, and dopaminergic neurons, but was not detectable in VGLUT-1-positive glutamatergic neurons and astrocytes
    Language English
    Publishing date 2024-01-19
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2024.01.17.575386
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Crowdsourcing anaesthesia care. Comment on Br J Anaesth 2016; 117: 276-279.

    Nguyen, The-Hung / Chambers, Chester G / Dada, Maqbool

    British journal of anaesthesia

    2021  Volume 127, Issue 5, Page(s) e176–e177

    MeSH term(s) Anesthesia, General ; Anesthesiology ; Crowdsourcing ; Humans
    Language English
    Publishing date 2021-08-19
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 80074-0
    ISSN 1471-6771 ; 0007-0912
    ISSN (online) 1471-6771
    ISSN 0007-0912
    DOI 10.1016/j.bja.2021.07.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uk I Zs.80: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Book ; Online: Michael J. Shapiro

    Shapiro, Michael J / Carver, Terrell / Chambers, Samuel Allen

    discourse, culture, violence

    (Routledge Innovators in Political Theory)

    2012  

    Abstract: Includes bibliographical references andb index ...

    Author's details edited by Terrell Carver and Samuel A. Chambers
    Series title Routledge Innovators in Political Theory
    Abstract Includes bibliographical references and index

    Michael J. Shapiro's writings have been innovatory with respect to the phenomena he has taken to be political, and the concomitant array of methods that he has brilliantly mastered. This book draws from his vast output of articles, chapters and books to provide a thematic yet integrated account of his boundary-crossing innovations in political theory and masterly contributions to our understanding of methods in the social sciences. The editors have focused on work in three key areas: Discourse Shapiro was one of the first theorists to demonstrate convincingly, and in a manner that has had a lo
    Language English
    Size Online-Ressource
    Publisher Routledge
    Publishing place Abingdon, Oxon
    Document type Book ; Online
    Note This collection contains Shapiro's seminal writings on discourse, culture and violence
    ISBN 1280647310 ; 1280660767 ; 9780203123645 ; 9780415783460 ; 9780415783477 ; 9781136340543 ; 9781280660764 ; 9781280647314 ; 0203123646 ; 0415783461 ; 041578347X ; 1136340548
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  5. Article: William J. Gies: a man of his word.

    Chambers, David W

    The Journal of the American College of Dentists

    2012  Volume 79, Issue 2, Page(s) 2–4

    MeSH term(s) Dentists/history ; Education, Dental/history ; History, 20th Century ; United States
    Language English
    Publishing date 2012
    Publishing country United States
    Document type Biography ; Editorial ; Historical Article
    ZDB-ID 410447-x
    ISSN 0002-7979
    ISSN 0002-7979
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 574: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Corrigendum to 'A comparison of early redo surgery rates in Mosaic porcine and Perimount bovine pericardial valves' [Eur J Cardiothorac Surg 2018; doi:10.1093/ejcts/ezy113].

    Webb, Jessica / Parkin, Denise / Tøndel, Kristin / Simitsis, Panagiotis / Roxburgh, James / Chambers, John B

    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

    2018  Volume 53, Issue 6, Page(s) 1301

    Language English
    Publishing date 2018-09-14
    Publishing country Germany
    Document type Journal Article ; Published Erratum
    ZDB-ID 639293-3
    ISSN 1873-734X ; 1010-7940 ; 1567-4258
    ISSN (online) 1873-734X
    ISSN 1010-7940 ; 1567-4258
    DOI 10.1093/ejcts/ezy192
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2303: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Book ; Online ; E-Book: Echocardiography

    Demetrescu, Camelia / Hothi, Sandeep S. / Chambers, John / Rimington, Helen

    a practical guide for reporting and interpretation

    2024  

    Author's details Camelia Demetrescu, Sandeep S Hothi, John Chambers
    Language English
    Size 1 Online-Ressource (xviii, 250 Seiten), Illustrationen, Diagramme
    Edition Fourth edition
    Publisher CRC Press, Taylor & Francis Group
    Publishing place Boca Raton
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT030660808
    ISBN 978-1-000-85571-5 ; 978-1-003-24278-9 ; 9781032151601 ; 9781032151588 ; 1-000-85571-6 ; 1-003-24278-2 ; 1032151609 ; 1032151587
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  8. Book ; Online ; E-Book: Field guide to global health & disaster medicine

    Chambers, James J.

    2021  

    Abstract: While serving as a physician overseas in resource-poor countries, Dr. James Chambers recognized ...

    Title variant Field guide to global health and disaster medicine
    Author's details James Chambers
    Abstract While serving as a physician overseas in resource-poor countries, Dr. James Chambers recognized the need for a practical, portable reference for non-specialist healthcare providers to orient them to common issues when serving in new situations, whether due to geography, austere environments, or complex humanitarian disasters. Field Guide to Global Health and Disaster Medicine draws on the experience, training, and perspectives of committed healthcare providers from diverse nations and backgrounds to provide the most essential information for maximum utility in the field-whether in a refugee camp, operating room, disaster response scene, or other demanding environment. Helps providers prepare for service overseas, organize data to develop differential diagnoses, assimilate information on infectious and environmental diseases, and effectively serve the patients they will encounter. Provides concise, easy-to-read coverage of how to approach a differential diagnosis for infectious diseases overseas; nutritional, sexual, and environmental conditions; surgical and anesthesia care; long-term and short-term systems-based challenges, and more. Covers key topics such as Approach to Refugees and Internally Displaced Persons, Medical Response to Disasters, Mental Health in War and Crisis Regions, and Considerations for Pandemic Preparedness and Response. Acknowledges the wide variance of different cultures, motives, resources, and limitations in the global health arena, and helps readers understand the factors which impact the efficacy and sustainability of care strategies. Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices.
    MeSH term(s) Disaster Medicine/methods. ; Disaster Medicine. ; Global Health. ; Medical Missions.
    Keywords Disaster medicine
    Subject code 362.18
    Language English
    Dates of publication 2021-2022
    Size 1 online resource (420 pages)
    Publisher Elsevier
    Publishing place Philadelphia, Pennsylvania
    Document type Book ; Online ; E-Book
    Note Includes index.
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 0-323-79413-0 ; 0-323-79412-2 ; 978-0-323-79413-8 ; 978-0-323-79412-1
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  9. Article ; Online: Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.

    Ru, Heng / Chambers, Melissa G / Fu, Tian-Min / Tong, Alexander B / Liao, Maofu / Wu, Hao

    Cell

    2015  Volume 163, Issue 5, Page(s) 1138–1152

    Abstract: ... segments by V(D)J recombination are hallmarks of vertebrate immunity. The (RAG1-RAG2)2 recombinase (RAG ...

    Abstract Diverse repertoires of antigen-receptor genes that result from combinatorial splicing of coding segments by V(D)J recombination are hallmarks of vertebrate immunity. The (RAG1-RAG2)2 recombinase (RAG) recognizes recombination signal sequences (RSSs) containing a heptamer, a spacer of 12 or 23 base pairs, and a nonamer (12-RSS or 23-RSS) and introduces precise breaks at RSS-coding segment junctions. RAG forms synaptic complexes only with one 12-RSS and one 23-RSS, a dogma known as the 12/23 rule that governs the recombination fidelity. We report cryo-electron microscopy structures of synaptic RAG complexes at up to 3.4 Å resolution, which reveal a closed conformation with base flipping and base-specific recognition of RSSs. Distortion at RSS-coding segment junctions and base flipping in coding segments uncover the two-metal-ion catalytic mechanism. Induced asymmetry involving tilting of the nonamer-binding domain dimer of RAG1 upon binding of HMGB1-bent 12-RSS or 23-RSS underlies the molecular mechanism for the 12/23 rule.
    MeSH term(s) Amino Acid Sequence ; Animals ; Cryoelectron Microscopy ; DNA-Binding Proteins/chemistry ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/ultrastructure ; Homeodomain Proteins/chemistry ; Homeodomain Proteins/genetics ; Homeodomain Proteins/ultrastructure ; Humans ; Mice ; Molecular Sequence Data ; Multiprotein Complexes/chemistry ; Multiprotein Complexes/ultrastructure ; Mutation ; Sequence Alignment ; V(D)J Recombination ; Zebrafish
    Chemical Substances DNA-Binding Proteins ; Homeodomain Proteins ; Multiprotein Complexes ; V(D)J recombination activating protein 2 ; RAG-1 protein (128559-51-3)
    Language English
    Publishing date 2015-11-19
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 187009-9
    ISSN 1097-4172 ; 0092-8674
    ISSN (online) 1097-4172
    ISSN 0092-8674
    DOI 10.1016/j.cell.2015.10.055
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1167: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 58: Show issues

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  10. Article: Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures

    Ru, Heng / Melissa G. Chambers / Tian-Min Fu / Alexander B. Tong / Maofu Liao / Hao Wu

    Cell. 2015 Nov. 19, v. 163

    2015  

    Abstract: ... segments by V(D)J recombination are hallmarks of vertebrate immunity. The (RAG1-RAG2)2 recombinase (RAG ...

    Abstract Diverse repertoires of antigen-receptor genes that result from combinatorial splicing of coding segments by V(D)J recombination are hallmarks of vertebrate immunity. The (RAG1-RAG2)2 recombinase (RAG) recognizes recombination signal sequences (RSSs) containing a heptamer, a spacer of 12 or 23 base pairs, and a nonamer (12-RSS or 23-RSS) and introduces precise breaks at RSS-coding segment junctions. RAG forms synaptic complexes only with one 12-RSS and one 23-RSS, a dogma known as the 12/23 rule that governs the recombination fidelity. We report cryo-electron microscopy structures of synaptic RAG complexes at up to 3.4 Å resolution, which reveal a closed conformation with base flipping and base-specific recognition of RSSs. Distortion at RSS-coding segment junctions and base flipping in coding segments uncover the two-metal-ion catalytic mechanism. Induced asymmetry involving tilting of the nonamer-binding domain dimer of RAG1 upon binding of HMGB1-bent 12-RSS or 23-RSS underlies the molecular mechanism for the 12/23 rule.
    Keywords cryo-electron microscopy ; genes ; immunity ; signal peptide ; vertebrates
    Language English
    Dates of publication 2015-1119
    Size p. 1138-1152.
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 187009-9
    ISSN 1097-4172 ; 0092-8674
    ISSN (online) 1097-4172
    ISSN 0092-8674
    DOI 10.1016/j.cell.2015.10.055
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 75/702: Show issues
    Z 93: Show issues

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