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Article ; Online: Effects of pre-steaming treatment on high-temperature and low-humidity drying characteristics of super-heavy timber with boxed-heart of Korean red pine and Douglas-fir

Yi, Nam-ho / Lee, Changjin

Drying Technology. 2023 Apr. 10, v. 41, no. 5 p.794-803

2023

Abstract: This study aimed to investigate how pre-steaming affects the drying times, final moisture contents (final MCs), and prevention of checking during the high-temperature and low-humidity drying process of boxed-heartwood Korean red pine (Pinus densiflora S. ...

Abstract	This study aimed to investigate how pre-steaming affects the drying times, final moisture contents (final MCs), and prevention of checking during the high-temperature and low-humidity drying process of boxed-heartwood Korean red pine (Pinus densiflora S. et Z.) and Douglas-fir (Pseudotsuga menziesii) with 20 × 20 cm and with 30 × 30 cm cross sections. Although average final MCs of the larger cross sections were slightly higher than those of smaller cross sections, all were over-dried between 3.3% and 8.1% MC, compared to the in-use moisture content for outdoor building materials. All the pre-steamed samples were only slightly defected by surface checks of 5 mm or less in width. The sample timbers with the 20 × 20 cm cross-sectional size were slightly defected by internal checking, whereas those with the 30 × 30 cm cross-sectional size were severely defected. However, there was no clear impact of pre-steaming time on the prevention of internal checking.
Keywords	Pinus densiflora ; Pseudotsuga menziesii ; technology ; water content ; Final moisture content ; moisture gradient ; surface checks ; internal checks
Language	English
Dates of publication	2023-0410
Size	p. 794-803.
Publishing place	Taylor & Francis
Document type	Article ; Online
ZDB-ID	2049461-0
ISSN	1532-2300 ; 0737-3937
ISSN (online)	1532-2300
ISSN	0737-3937
DOI	10.1080/07373937.2022.2119246
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Prospective comparative analysis of noninvasive body temperature monitoring using zero heat flux technology (SpotOn sensor) compared with esophageal temperature monitoring during pediatric surgery.

Bo-Hyun Sang / Changjin Lee / Da Yeong Lee

PLoS ONE, Vol 17, Iss 8, p e

2022 Volume 0272720

Abstract: Maintaining body temperature in pediatric patients is critical, but it is often difficult to use currently accepted core temperature measurement methods. Several studies have validated the use of the SpotOn sensor for measuring core temperature in adults, ...

Abstract	Maintaining body temperature in pediatric patients is critical, but it is often difficult to use currently accepted core temperature measurement methods. Several studies have validated the use of the SpotOn sensor for measuring core temperature in adults, but studies on pediatric patients are still lacking. The aim of this study was to investigate the accuracy of the SpotOn sensor compared with that of esophageal temperature measurement in pediatric patients intraoperatively. Children aged 1-8 years with American Society of Anesthesiology Physical Condition Classification I or II scheduled to undergo elective ear surgery for at least 30 min under general anesthesia were enrolled. Body core temperature was measured every 15 min after induction till the end of anesthesia with an esophageal probe, axillary probe, and SpotOn sensor. We included 49 patients, providing a total 466 paired measurements. Analysis of Pearson rank correlation between SpotOn and esophageal pairs showed a correlation coefficient (r) of 0.93 (95% confidence interval [CI] 0.92-0.94). Analysis of Pearson rank correlation between esophageal and axillary pairs gave a correlation coefficient (r) of 0.89 (95% CI 0.87-0.91). Between the SpotOn and esophageal groups, Bland-Altman analysis revealed a bias (SD, 95% limits of agreement) of -0.07 (0.17 [-0.41-0.28]). Between the esophageal and axillary groups, Bland-Altman analysis showed a bias (SD, 95% limits of agreement) of 0.45 (0.22 [0-0.89]). In pediatric patients during surgery, the SpotOn sensor showed high correlation and agreement with the esophageal probe, which is a representative core temperature measurement method.
Keywords	Medicine ; R ; Science ; Q
Subject code	541
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Prospective comparative analysis of noninvasive body temperature monitoring using zero heat flux technology (SpotOn sensor) compared with esophageal temperature monitoring during pediatric surgery.

Sang, Bo-Hyun / Lee, Changjin / Lee, Da Yeong

PloS one

2022 Volume 17, Issue 8, Page(s) e0272720

Abstract	Maintaining body temperature in pediatric patients is critical, but it is often difficult to use currently accepted core temperature measurement methods. Several studies have validated the use of the SpotOn sensor for measuring core temperature in adults, but studies on pediatric patients are still lacking. The aim of this study was to investigate the accuracy of the SpotOn sensor compared with that of esophageal temperature measurement in pediatric patients intraoperatively. Children aged 1-8 years with American Society of Anesthesiology Physical Condition Classification I or II scheduled to undergo elective ear surgery for at least 30 min under general anesthesia were enrolled. Body core temperature was measured every 15 min after induction till the end of anesthesia with an esophageal probe, axillary probe, and SpotOn sensor. We included 49 patients, providing a total 466 paired measurements. Analysis of Pearson rank correlation between SpotOn and esophageal pairs showed a correlation coefficient (r) of 0.93 (95% confidence interval [CI] 0.92-0.94). Analysis of Pearson rank correlation between esophageal and axillary pairs gave a correlation coefficient (r) of 0.89 (95% CI 0.87-0.91). Between the SpotOn and esophageal groups, Bland-Altman analysis revealed a bias (SD, 95% limits of agreement) of -0.07 (0.17 [-0.41-0.28]). Between the esophageal and axillary groups, Bland-Altman analysis showed a bias (SD, 95% limits of agreement) of 0.45 (0.22 [0-0.89]). In pediatric patients during surgery, the SpotOn sensor showed high correlation and agreement with the esophageal probe, which is a representative core temperature measurement method.
MeSH term(s)	Adult ; Body Temperature ; Child ; Hot Temperature ; Humans ; Monitoring, Intraoperative/methods ; Prospective Studies ; Technology ; Temperature
Language	English
Publishing date	2022-08-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0272720
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Clot-Targeted Antithrombotic Liposomal Nanomedicine Containing High Content of H

Jeon, Chanhee / Jun, Hayoung / Kim, Sooyeon / Song, Nanhee / Yang, Manseok / Lim, Changjin / Lee, Dongwon

ACS applied materials & interfaces

2023

Abstract: Liposomes have been extensively explored as drug carriers, but their clinical translation has been hampered by their low drug-loading content and premature leakage of drug payloads. It was reasoned that vesicle-forming prodrugs could be incorporated into ...

Abstract	Liposomes have been extensively explored as drug carriers, but their clinical translation has been hampered by their low drug-loading content and premature leakage of drug payloads. It was reasoned that vesicle-forming prodrugs could be incorporated into the lipid bilayer at a high molar fraction and therefore serve as a therapeutic agent as well as a structural component in liposomal nanomedicine. Boronated retinoic acid (BORA) was developed as a prodrug, which can self-assemble with common lipids to form liposomes at a high molar fraction (40%) and release all-
Language	English
Publishing date	2023-02-07
Publishing country	United States
Document type	Journal Article
ISSN	1944-8252
ISSN (online)	1944-8252
DOI	10.1021/acsami.2c20750
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Structural Congeners of Izenamides Responsible for Cathepsin D Inhibition: Insights from Synthesis-Derived Elucidation.

Kim, Hyun Su / Kong, Hyejin / Kim, Taewoo / Lim, Changjin / Lee, Seungbeom / Kim, Seok-Ho / Suh, Young-Ger

Marine drugs

2023 Volume 21, Issue 5

Abstract: This study aimed to elucidate the structural congeners of natural izenamides A, B, and C ( ...

Abstract	This study aimed to elucidate the structural congeners of natural izenamides A, B, and C (
MeSH term(s)	Humans ; Cathepsin D ; Protease Inhibitors/pharmacology ; Protease Inhibitors/chemistry
Chemical Substances	Cathepsin D (EC 3.4.23.5) ; Protease Inhibitors
Language	English
Publishing date	2023-04-28
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2175190-0
ISSN	1660-3397 ; 1660-3397
ISSN (online)	1660-3397
ISSN	1660-3397
DOI	10.3390/md21050281
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Characteristics of radio-frequency/vacuum combined with mechanical press drying of heavy softwood timbers with longitudinal kerf

Zhao, Xuefeng / Lee, Changjin

Holzforschung. 2021 Jan. 26, v. 75, no. 1

2021

Abstract: The aim of this study was to evaluate the characteristics of radio-frequency/vacuum combined with mechanical press (RF/VP) drying on three softwood timbers (Douglas fir, Hemlock, and Radiata pine) with longitudinal kerfs. The results were as follows: Due ...

Abstract	The aim of this study was to evaluate the characteristics of radio-frequency/vacuum combined with mechanical press (RF/VP) drying on three softwood timbers (Douglas fir, Hemlock, and Radiata pine) with longitudinal kerfs. The results were as follows: Due to the dielectric permittivity of wood, RF/VP drying at a fixed frequency of 13.56 MHz significantly influenced the moisture content (MC) distribution, the number of surface checks, shrinkage, and warp. These observations were attributed to the formation of a temperature gradient along the charge plate during the drying. The presence or absence of pith, more affected an occurrence of surface checks than that of the stresses within the wood during drying. The longitudinal kerf reduced the number of surface checks, but did not affect the MC distribution or the twist after drying.
Keywords	Pinus radiata ; Pseudotsuga menziesii ; dielectric permittivity ; pith ; shrinkage ; softwood ; temperature ; water content
Language	English
Dates of publication	2021-0126
Size	p. 48-55.
Publishing place	De Gruyter
Document type	Article
Note	NAL-AP-2-clean
ZDB-ID	1466072-6
ISSN	1437-434X ; 0018-3830
ISSN (online)	1437-434X
ISSN	0018-3830
DOI	10.1515/hf-2019-0261
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Risk factors for severe postpartum hemorrhage requiring blood transfusion after cesarean delivery for twin pregnancy

Gi Hyeon Seo / Jong Yeop Kim / Da Yeong Lee / Changjin Lee / Jiyoung Lee

Anesthesia and Pain Medicine, Vol 18, Iss 4, Pp 367-

a nationwide cohort study

2023 Volume 375

Abstract: Background Postpartum hemorrhage (PPH) is a leading cause of maternal morbidity and mortality. Twin pregnancy and cesarean delivery are well-known risk factors for PPH. However, few studies have investigated PPH risk factors in mothers who have undergone ...

Abstract	Background Postpartum hemorrhage (PPH) is a leading cause of maternal morbidity and mortality. Twin pregnancy and cesarean delivery are well-known risk factors for PPH. However, few studies have investigated PPH risk factors in mothers who have undergone cesarean delivery for twin pregnancies. Therefore, this study investigated the risk factors associated with severe PPH after cesarean delivery for twin pregnancies. Methods We searched and reviewed the Korean Health Insurance Review and Assessment Service’s claims data from July 2008 to June 2021 using the code corresponding to cesarean delivery for twin pregnancy. Severe PPH was defined as hemorrhage requiring red blood cell (RBC) transfusion during the peripartum period. The risk factors associated with severe PPH were identified among the procedure and diagnosis code variables and analyzed using univariate and multivariate logistic regressions. Results We analyzed 31,074 cesarean deliveries for twin pregnancies, and 4,892 patients who underwent cesarean deliveries for twin pregnancies and received RBC transfusions for severe PPH were included. According to the multivariate analysis, placental disorders (odds ratio, 4.50; 95% confidence interval, 4.09–4.95; P < 0.001), general anesthesia (2.33, 2.18–2.49; P < 0.001), preeclampsia (2.20, 1.99–2.43; P < 0.001), hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome (2.12, 1.22–3.68; P = 0.008), induction failure (1.37, 1.07–1.76; P = 0.014), and hypertension (1.31, 1.18–1.44; P < 0.001) predicted severe PPH. Conclusions Placental disorders, hypertensive disorders such as preeclampsia and HELLP syndrome, and induction failure increased the risk of severe PPH after cesarean delivery for twin pregnancy.
Keywords	blood transfusion ; cesarean section ; morbidity ; national cohort ; postpartum hemorrhage ; pregnancy ; twin ; Anesthesiology ; RD78.3-87.3 ; Medicine ; R
Subject code	610
Language	English
Publishing date	2023-10-01T00:00:00Z
Publisher	Korean Society of Anesthesiologists
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Risk factors for severe postpartum hemorrhage requiring blood transfusion after cesarean delivery for twin pregnancy: a nationwide cohort study.

Seo, Gi Hyeon / Kim, Jong Yeop / Lee, Da Yeong / Lee, Changjin / Lee, Jiyoung

Anesthesia and pain medicine

2023 Volume 18, Issue 4, Page(s) 367–375

Abstract: Background: Postpartum hemorrhage (PPH) is a leading cause of maternal morbidity and mortality. Twin pregnancy and cesarean delivery are well-known risk factors for PPH. However, few studies have investigated PPH risk factors in mothers who have ... ...

Abstract	Background: Postpartum hemorrhage (PPH) is a leading cause of maternal morbidity and mortality. Twin pregnancy and cesarean delivery are well-known risk factors for PPH. However, few studies have investigated PPH risk factors in mothers who have undergone cesarean delivery for twin pregnancies. Therefore, this study investigated the risk factors associated with severe PPH after cesarean delivery for twin pregnancies. Methods: We searched and reviewed the Korean Health Insurance Review and Assessment Service's claims data from July 2008 to June 2021 using the code corresponding to cesarean delivery for twin pregnancy. Severe PPH was defined as hemorrhage requiring red blood cell (RBC) transfusion during the peripartum period. The risk factors associated with severe PPH were identified among the procedure and diagnosis code variables and analyzed using univariate and multivariate logistic regressions. Results: We analyzed 31,074 cesarean deliveries for twin pregnancies, and 4,892 patients who underwent cesarean deliveries for twin pregnancies and received RBC transfusions for severe PPH were included. According to the multivariate analysis, placental disorders (odds ratio, 4.50; 95% confidence interval, 4.09- 4.95; P < 0.001), general anesthesia (2.33, 2.18-2.49; P < 0.001), preeclampsia (2.20, 1.99-2.43; P < 0.001), hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome (2.12, 1.22-3.68; P = 0.008), induction failure (1.37, 1.07-1.76; P = 0.014), and hypertension (1.31, 1.18-1.44; P < 0.001) predicted severe PPH. Conclusions: Placental disorders, hypertensive disorders such as preeclampsia and HELLP syndrome, and induction failure increased the risk of severe PPH after cesarean delivery for twin pregnancy.
Language	English
Publishing date	2023-08-08
Publishing country	Korea (South)
Document type	Journal Article
ISSN	2383-7977
ISSN (online)	2383-7977
DOI	10.17085/apm.23019
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Increased risk of contralateral breast cancer for BRCA1/2 wild-type, high-risk Korean breast cancer patients: a retrospective cohort study.

Kang, Eunhye / Jung, Ji-Jung / Lim, Changjin / Kim, Hong-Kyu / Lee, Han-Byoel / Han, Wonshik / Moon, Hyeong-Gon

Breast cancer research : BCR

2024 Volume 26, Issue 1, Page(s) 14

Abstract: Background: This study aimed to investigate the contralateral breast cancer (CBC) recurrence rate in Korean breast cancer patients according to their BRCA1/2 germline mutation status, focusing particularly on the CBC recurrence risk in BRCA1/2 negative ( ...

Abstract	Background: This study aimed to investigate the contralateral breast cancer (CBC) recurrence rate in Korean breast cancer patients according to their BRCA1/2 germline mutation status, focusing particularly on the CBC recurrence risk in BRCA1/2 negative (BRCAx) patients. Methods: We conducted a retrospective study on 13,107 primary breast cancer patients. The patients were divided into high-risk and low-risk groups for hereditary breast cancer based on the Korean National Health Insurance Service's eligibility criteria for BRCA1/2 germline mutation testing. The high-risk group was further categorized into the BRCA mutation group, the BRCAx group, and the not tested group. We evaluated the overall survival and cumulative risk of developing CBC in these patients. Results: Among 4494 high-risk patients, 973 (21.7%) underwent genetic testing for BRCA1/2 germline mutation, revealing mutations in 158 patients (16.2%). We observed significant overall survival differences across all four groups, with the high-risk, not-tested group demonstrating notably worse overall survival (p < 0.001). However, when adjusted for other prognostic factors, there was no significant differences in hazard ratio of death between the four groups. The cumulative risk of CBC also varied among the groups. Patients with BRCA1/2 mutations showed a 7.3-fold increased risk of CBC compared to the low-risk group (95% CI 4.11-13.0, p < 0.001). Interestingly, BRCAx patients also demonstrated a significantly higher risk of CBC (HR 2.77, 95% CI 1.76-4.35, p < 0.001). The prognostic importance of the BRCAx for CBC recurrence persisted after adjusting for the age and subtype, but became insignificant when the family history of breast cancer was adjusted. Conclusion: Breast cancer patients who are at high risk of hereditary breast cancer but with wild-type BRCA 1/2 genes (BRCAx) have increased risk of developing contralateral breast cancer when compared to the low-risk patients. More careful surveillance and follow-up can be offered to these patients especially when they have family history of breast cancer.
MeSH term(s)	Humans ; Female ; BRCA1 Protein/genetics ; Breast Neoplasms/epidemiology ; Breast Neoplasms/genetics ; Retrospective Studies ; BRCA2 Protein/genetics ; Republic of Korea/epidemiology
Chemical Substances	BRCA1 protein, human ; BRCA1 Protein ; BRCA2 protein, human ; BRCA2 Protein
Language	English
Publishing date	2024-01-22
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2015059-3
ISSN	1465-542X ; 1465-5411
ISSN (online)	1465-542X
ISSN	1465-5411
DOI	10.1186/s13058-024-01769-x
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Postoperative alterations in ventriculoarterial coupling are an indicator of cardiovascular outcomes in liver transplant recipients.

Kim, Ji Yeon / Moon, Young-Jin / Lee, Changjin / Kim, Jin Ho / Park, Junghyun / Kim, Jung-Won

Korean journal of anesthesiology

2023 Volume 77, Issue 2, Page(s) 217–225

Abstract: Background: Liver transplantation (LT) increases the heart and vessel workload in patients with cirrhotic cardiomyopathy. While the interaction of the left ventricle (LV) with the arterial system (ventriculoarterial coupling, VAC) is a key determinant ... ...

Abstract	Background: Liver transplantation (LT) increases the heart and vessel workload in patients with cirrhotic cardiomyopathy. While the interaction of the left ventricle (LV) with the arterial system (ventriculoarterial coupling, VAC) is a key determinant of cardiovascular performance, little is known about changes in VAC after LT. Therefore, we evaluated the relationship between VAC after LT and cardiovascular outcomes. Methods: 344 consecutive patients underwent echocardiographic assessments before and within 30 days after LT. Non-invasive arterial elastance (Ea), LV end-systolic elastance (Ees), and LV end-diastolic elastance (Eed) were calculated. The postoperative outcomes included the development of major adverse cardiovascular events (MACE) and the length of stay in the intensive care unit and hospital. Results: A total of 240 patients were included in the analyses. After LT, Ea increased by 16% (P < 0.001), and Ees and contractility index of systolic velocity (S') increased by 18% (P < 0.001) and 7% (P < 0.001), respectively. The Eed increased by 6% (P < 0.001). The VAC remained unchanged (0.56 to 0.56, P = 0.912). Of these patients, 29 had MACE, and those with MACE had significantly higher postoperative VAC. Additionally, a higher postoperative VAC was an independent risk factor for a longer postoperative hospital stay (P = 0.038). Conclusions: These data suggest that ventriculoarterial decoupling is associated with poor postoperative outcomes after LT.
MeSH term(s)	Humans ; Liver Transplantation ; Heart Ventricles/diagnostic imaging ; Echocardiography
Language	English
Publishing date	2023-07-12
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2557340-8
ISSN	2005-7563 ; 2005-7563
ISSN (online)	2005-7563
ISSN	2005-7563
DOI	10.4097/kja.23266
Database	MEDical Literature Analysis and Retrieval System OnLINE

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