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Article ; Online: Temporal trend of Tuberculosis incidence in northeastern Brazilian municipalities according to Social Vulnerability Index parameters: An ecological study.

Paiva, João P S / Brito, Alyne B / Bezerra-Santos, Márcio / Carmo, Rodrigo F / Souza, Carlos D F

Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia

2023 Volume 49, Issue 1, Page(s) e20220353

MeSH term(s)	Humans ; Cities ; Incidence ; Brazil/epidemiology ; Social Vulnerability ; Tuberculosis/epidemiology
Language	Portuguese
Publishing date	2023-01-23
Publishing country	Brazil
Document type	Letter
ZDB-ID	2223157-2
ISSN	1806-3756 ; 1806-3713
ISSN (online)	1806-3756
ISSN	1806-3713
DOI	10.36416/1806-3756/e20220353
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Temporal and spatial trends in human visceral leishmaniasis in an endemic area in Northeast Brazil and their association with social vulnerability.

Andrade, Acácio W F / Souza, Carlos D F / Carmo, Rodrigo F

Transactions of the Royal Society of Tropical Medicine and Hygiene

2021 Volume 116, Issue 5, Page(s) 469–478

Abstract: Background: Visceral leishmaniasis is a neglected tropical disease of great importance to public health due to its wide distribution and close relationship with social and economic conditions. This study aimed to analyse the spatiotemporal dynamics of ... ...

Abstract	Background: Visceral leishmaniasis is a neglected tropical disease of great importance to public health due to its wide distribution and close relationship with social and economic conditions. This study aimed to analyse the spatiotemporal dynamics of human visceral leishmaniasis (HVL) in an endemic state in the Northeast Region of Brazil and its spatial correlation with the Social Vulnerability Index (SVI) and the Municipal Human Development Index (MHDI). Methods: The study included all confirmed cases of HVL in Bahia from 2010 to 2017. A joinpoint regression model was used for trend analysis. Incidence rates were smoothed by a local empirical Bayesian model. Global and local Moran indices and space-time scan statistics were used for identification of spatial clusters. Bivariate and multivariate analyses were carried out to investigate the relationship between HVL incidence and the SVI and MHDI. Results: Cases of HVL demonstrated stationary behaviour during the period analysed. A significant association was observed between the HVL incidence rate and social vulnerability, with high-risk clusters concentrated in the central region of the state. Conclusions: HVL has a strong correlation with social vulnerability in the state of Bahia. This study may provide assistance in planning actions and organizing health services to combat HVL.
MeSH term(s)	Bayes Theorem ; Brazil/epidemiology ; Humans ; Incidence ; Leishmaniasis, Visceral/epidemiology ; Neglected Diseases ; Social Vulnerability
Language	English
Publishing date	2021-10-18
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	441375-1
ISSN	1878-3503 ; 0035-9203
ISSN (online)	1878-3503
ISSN	0035-9203
DOI	10.1093/trstmh/trab160
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Article: Environmental conditions differently affect the wing size and shape of two blow fly species (Calliphoridae) of forensic importance in the Brazilian tropical ecosystems

Carmo, Rodrigo F. R. / Astúa, Diego / Vasconcelos, Simão D.

International journal of tropical insect science. 2022 Apr., v. 42, no. 2

2022

Abstract: Environmental pressures challenge the survivorship of wildlife, and adaptive ability is key to their success and establishment. However, it remains unclear how changes in environmental conditions affect the phenotypic plasticity of some species. Studies ... ...

Abstract	Environmental pressures challenge the survivorship of wildlife, and adaptive ability is key to their success and establishment. However, it remains unclear how changes in environmental conditions affect the phenotypic plasticity of some species. Studies that consider the effect of the environment (e.g., climate changes) on species morphology are essential to better understand his potential resilience. Thus, Diptera species appear as an excellent model. Here we investigated the effect of environmental conditions on wing size and shape within and between one native and one invasive blowfly species populations, along an ecoregional gradient in Brazil. For native species, wing size was affected by almost all environmental variables, while wing shape was unaffected. For invasive species, humidity best explained both wing size and wing shape variation. Our results show a differentiation between populations for both species, but a transversal comparison reveals that invasive species do not seem to be affected in the same way as the native species by climatic variations in the field. Temperature and humidity are the most significant environmental variables associated with differences in wing size and shape for invasive species, indicating an elevated climate tolerance of this species, which may be associated with its invasive characteristics and adaptive potential. Thus, our findings shed light on the importance of assessing the individual and compound effect of environmental variation and biological invasion on the adaptation of native species, since it is expected to increase 3 °C with a 20% overall reduction in the amount of rainfall in the tropical region of Brazil by 2100.
Keywords	Calliphoridae ; ecological invasion ; environmental factors ; forensic sciences ; humidity ; indigenous species ; insects ; invasive species ; models ; phenotypic plasticity ; rain ; survival rate ; temperature ; tropics ; wildlife ; Brazil
Language	English
Dates of publication	2022-04
Size	p. 1903-1911.
Publishing place	Springer International Publishing
Document type	Article
ZDB-ID	2166668-4
ISSN	1742-7592 ; 1742-7584
ISSN (online)	1742-7592
ISSN	1742-7584
DOI	10.1007/s42690-021-00720-3
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Analysis of spatial clustering, time trend, social vulnerability and risk of human visceral leishmaniasis in an endemic area in Brazil: an ecological study.

Andrade, Acácio W F / Souza, Carlos D F / Carmo, Rodrigo F

Transactions of the Royal Society of Tropical Medicine and Hygiene

2020 Volume 114, Issue 8, Page(s) 575–584

Abstract: Background: More than 95% of visceral leishmaniasis (VL) cases in Latin America occur in Brazil, most of them in the northeast. The objective of this study was to identify spatial clusters with the highest risks of VL and to analyse the temporal ... ...

Abstract	Background: More than 95% of visceral leishmaniasis (VL) cases in Latin America occur in Brazil, most of them in the northeast. The objective of this study was to identify spatial clusters with the highest risks of VL and to analyse the temporal behaviour of the incidence and the effects of social vulnerability on the disease transmission dynamic in northeastern Brazil. Methods: All confirmed cases registered as residents in the state of Pernambuco during the period from 2007 to 2017 were analysed. The local empirical Bayesian method was applied and the association -between the VL incidence rate and municipal social vulnerability was tested via classic multivariate regression. Results: A total of 1186 new cases were registered during the study period. Spatial analysis showed heterogeneous distribution, with the highest rates observed in the São Francisco and Sertão mesoregions. Moreover, the main factors associated with VL were urban infrastructure, income and work. Conclusions: It was observed that spatial and temporal techniques are important tools for defining risk areas for VL, in conjunction with the evaluation of indexes of social vulnerability, which was shown to be an important factor for comprehending associations with VL in the state of Pernambuco.
MeSH term(s)	Bayes Theorem ; Brazil/epidemiology ; Cluster Analysis ; Humans ; Incidence ; Leishmaniasis, Visceral/epidemiology ; Spatial Analysis
Language	English
Publishing date	2020-04-16
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	441375-1
ISSN	1878-3503 ; 0035-9203
ISSN (online)	1878-3503
ISSN	0035-9203
DOI	10.1093/trstmh/traa024
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Article ; Online: Expansion of COVID-19 within Brazil: the importance of highways.

Carmo, Rodrigo F / Nunes, Bruno E B R / Machado, Michael F / Armstrong, Anderson C / Souza, Carlos D F

Journal of travel medicine

2020 Volume 27, Issue 5

MeSH term(s)	Betacoronavirus ; Brazil/epidemiology ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/transmission ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/transmission ; SARS-CoV-2 ; Spatial Analysis ; Travel
Keywords	covid19
Language	English
Publishing date	2020-06-29
Publishing country	England
Document type	Letter
ZDB-ID	1212504-0
ISSN	1708-8305 ; 1195-1982
ISSN (online)	1708-8305
ISSN	1195-1982
DOI	10.1093/jtm/taaa106
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Article ; Online: Risk factors for adverse drug events in hospitalized patients

Izabella V. GOMES / Charles R. MUNIZ / Ricardo S. VIEIRA / Raissa L. REIS / Rodrigo F. CARMO / Daniel T. SILVA

Revista Brasileira de Farmácia Hospitalar e Serviços de Saúde, Vol 13, Iss 1, Pp 738-

an overview of systematic reviews

2022 Volume 738

Abstract: Objectives: To perform an overview in order to identify risk factors related to the development of Adverse Drug Events (ADE) in hospitalized patients. Methods: A search for systematic reviews and meta-analyses was carried out in the Pubmed, Scopus, ... ...

Abstract	Objectives: To perform an overview in order to identify risk factors related to the development of Adverse Drug Events (ADE) in hospitalized patients. Methods: A search for systematic reviews and meta-analyses was carried out in the Pubmed, Scopus, Lilacs and Scielo databases, until August 19, 2021. The search strategies contained the following MeSH descriptors: Drug-Related Side Effects and Adverse Reactions; Inpatients; Hospitalization; Hospitals; Hospital; Logistics Models; Risk Factors; Drug Therapy; Risk Assessment; Pharmacy Service, Adverse Drug Events; Adverse Drug Reactions; Medication Errors; Risk; Systematic Review and Meta-Analysis. From this, publications in English, Portuguese or Spanish that exposed possible risk factors for ADE during hospitalization were included. Works were excluded when: characterized as narrative reviews, expert opinions, editorials, overview and reviews without a transparent search strategy; restricted to certain drug classes, patient groups or clinical features; reported only the assessment of Medication Errors (ME); they were duplicated; did not provide abstract and full text. Two independent authors performed the selection of studies, a third researcher was requested when there was disagreement. The studies that met the criteria for data extraction underwent a thematic analysis and, based on reading, the risk factors for ADE were raised. Results: Eleven studies met the inclusion criteria: ten systematic reviews and one meta-analysis. “Number of prescribed drugs” (OR: 1,21; CI95%: 1,03-1,44; p: 0,024), “Advanced age” (OR: 2,12; CI 95%: 1,70-2,65; p: 0,000) and “Comorbidities” were the most cited risk factors, other characteristics described less frequently were “Hospital Length (HL)”, “Allergies” and “Female sex”. Furthermore, it has been observed that the use of certain medications can increase the patient’s risk. Conclusions: The realization of overview made it possible to identify risk factors for ADE, which can help hospital teams to direct their care actions to ...
Keywords	Public aspects of medicine ; RA1-1270 ; Pharmacy and materia medica ; RS1-441 ; Therapeutics. Pharmacology ; RM1-950
Subject code	610
Language	English
Publishing date	2022-03-01T00:00:00Z
Publisher	Sociedade Brasileira de Farmácia Hospitalar e Serviços de Saúde
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Expansion of COVID-19 within Brazil: the importance of highways

Carmo, Rodrigo F / Nunes, Bruno E B R / Machado, Michael F / Armstrong, Anderson C / Souza, Carlos D F

J. travel med

Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #618842
Database	COVID19

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Article ; Online: Expansion of COVID-19 within Brazil

Carmo, Rodrigo F / Nunes, Bruno E B R / Machado, Michael F / Armstrong, Anderson C / Souza, Carlos D F

Journal of Travel Medicine

the importance of highways

2020 Volume 27, Issue 5

Keywords	General Medicine ; covid19
Language	English
Publisher	Oxford University Press (OUP)
Publishing country	uk
Document type	Article ; Online
ZDB-ID	1212504-0
ISSN	1708-8305 ; 1195-1982
ISSN (online)	1708-8305
ISSN	1195-1982
DOI	10.1093/jtm/taaa106
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Diversity of sarcosaprophagous Diptera (Calliphoridae, Sarcophagidae) in organic and conventional mango plantations in the Brazilian semi-arid region

Rodrigo F.R. Carmo / Taciano M. Barbosa / Aline F. Torris / Mary-Ann S. Bezerra / Simão D. Vasconcelos

Revista Brasileira de Entomologia, Vol 65, Iss

2021 Volume 1

Abstract: ABSTRACT Increase on intensive monocultures is an important threat to Caatinga biodiversity decrease. The use of chemical insecticides directly affects insect natural enemies of crops, but also non-target species. We aimed to test whether the diversity ... ...

Abstract	ABSTRACT Increase on intensive monocultures is an important threat to Caatinga biodiversity decrease. The use of chemical insecticides directly affects insect natural enemies of crops, but also non-target species. We aimed to test whether the diversity of sarcosaprophagous flies would be affected by agricultural management (conventional and organic). Adult dipterans were collected monthly, from July 2015 to January 2016, using a grid composed of 12 suspended traps distant 20 m from each other, baited with 150 g of sardine or bovine spleen, in each type of management. We first calculated α-diversity by Hill numbers, then evaluated the difference of diversity metrics by ANOVA. We also graphically visualise the species composition distribution by NMDS. We recorded a total of 4,651 specimens of 15 Calliphoridae and Sarcophagidae species. Chrysomya spp. were the dominant species (93.7% of all blowflies). Sarcophagidae species were sampled in low abundance, but with exclusive presence of some species in each treatment (e.g. B laesoxipha stallengi and Ravinia belforti in organic management). Although there was no difference on sarcosaprophagous fly diversity between treatments, we demonstrate empirically that mango plantations in the Caatinga harbour diverse and abundant assemblages of sarcosaprophagous dipterans, whose richness of species is comparable to other ecosystems such as rainforests and urban areas. Our results expand the known geographical range for forensically relevant species by providing a checklist of sarcosaprophagous dipterans that can thrive in agroecosystems in the Caatinga and, potentially, colonize cadavers disposed in that type of environment.
Keywords	Caatinga ; Agroecosystem ; Forensic Entomology ; Chrysomya ; Oxysarcodexia ; Zoology ; QL1-991
Subject code	590
Language	English
Publishing date	2021-03-01T00:00:00Z
Publisher	Sociedade Brasileira de Entomologia
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Role of Interleukin-22 in chronic liver injury.

Carmo, Rodrigo F / Cavalcanti, Maria S M / Moura, Patrícia

Cytokine

2016 Volume 98, Page(s) 107–114

Abstract: Liver fibrosis is the result of an exacerbated wound-healing response associated with chronic liver injury. Advanced liver fibrosis results in cirrhosis, liver failure, and portal hypertension and frequently requires liver transplantation. The host ... ...

Abstract	Liver fibrosis is the result of an exacerbated wound-healing response associated with chronic liver injury. Advanced liver fibrosis results in cirrhosis, liver failure, and portal hypertension and frequently requires liver transplantation. The host immune response has an important role driving fibrosis deposition by activating hepatic stellate cells (HSCs). Interleukin-22 (IL-22) is a cytokine that plays a key role in promoting antimicrobial immunity and tissue repair at barrier surfaces. Data from literature suggest that IL-22 has a protective role in the liver by reducing fibrosis in some pathological conditions, however the results are contradictory. This review highlights current knowledge of IL-22' role in chronic liver injury, as well as its therapeutic potential for the treatment of chronic liver injury.
MeSH term(s)	Animals ; Chronic Disease/therapy ; Disease Models, Animal ; Humans ; Interleukins/deficiency ; Interleukins/genetics ; Interleukins/immunology ; Interleukins/therapeutic use ; Liver/immunology ; Liver/pathology ; Liver Cirrhosis/immunology ; Liver Cirrhosis/metabolism ; Liver Cirrhosis/therapy ; Liver Diseases/immunology ; Liver Diseases/metabolism ; Liver Diseases/therapy ; Liver Transplantation ; Mice ; Interleukin-22
Chemical Substances	Interleukins
Language	English
Publishing date	2016-11-02
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	1018055-2
ISSN	1096-0023 ; 1043-4666
ISSN (online)	1096-0023
ISSN	1043-4666
DOI	10.1016/j.cyto.2016.08.023
Database	MEDical Literature Analysis and Retrieval System OnLINE

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