LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 56

Search options

  1. Article ; Online: RAxML Grove: an empirical phylogenetic tree database.

    Höhler, Dimitri / Pfeiffer, Wayne / Ioannidis, Vassilios / Stockinger, Heinz / Stamatakis, Alexandros

    Bioinformatics (Oxford, England)

    2021  Volume 38, Issue 6, Page(s) 1741–1742

    Abstract: Summary: The assessment of novel phylogenetic models and inference methods is routinely being conducted via experiments on simulated as well as empirical data. When generating synthetic data it is often unclear how to set simulation parameters for the ... ...

    Abstract Summary: The assessment of novel phylogenetic models and inference methods is routinely being conducted via experiments on simulated as well as empirical data. When generating synthetic data it is often unclear how to set simulation parameters for the models and generate trees that appropriately reflect empirical model parameter distributions and tree shapes. As a solution, we present and make available a new database called 'RAxML Grove' currently comprising more than 60 000 inferred trees and respective model parameter estimates from fully anonymized empirical datasets that were analyzed using RAxML and RAxML-NG on two web servers. We also describe and make available two simple applications of RAxML Grove to exemplify its usage and highlight its utility for designing realistic simulation studies and analyzing empirical model parameter and tree shape distributions.
    Availability and implementation: RAxML Grove is freely available at https://github.com/angtft/RAxMLGrove.
    Supplementary information: Supplementary data are available at Bioinformatics online.
    MeSH term(s) Phylogeny ; Software ; Computer Simulation ; Computers ; Databases, Factual
    Language English
    Publishing date 2021-12-29
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1422668-6
    ISSN 1367-4811 ; 1367-4803
    ISSN (online) 1367-4811
    ISSN 1367-4803
    DOI 10.1093/bioinformatics/btab863
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2374: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Expasy, the Swiss Bioinformatics Resource Portal, as designed by its users.

    Duvaud, Séverine / Gabella, Chiara / Lisacek, Frédérique / Stockinger, Heinz / Ioannidis, Vassilios / Durinx, Christine

    Nucleic acids research

    2021  Volume 49, Issue W1, Page(s) W216–W227

    Abstract: The SIB Swiss Institute of Bioinformatics (https://www.sib.swiss) creates, maintains and disseminates a portfolio of reliable and state-of-the-art bioinformatics services and resources for the storage, analysis and interpretation of biological data. ... ...

    Abstract The SIB Swiss Institute of Bioinformatics (https://www.sib.swiss) creates, maintains and disseminates a portfolio of reliable and state-of-the-art bioinformatics services and resources for the storage, analysis and interpretation of biological data. Through Expasy (https://www.expasy.org), the Swiss Bioinformatics Resource Portal, the scientific community worldwide, freely accesses more than 160 SIB resources supporting a wide range of life science and biomedical research areas. In 2020, Expasy was redesigned through a user-centric approach, known as User-Centred Design (UCD), whose aim is to create user interfaces that are easy-to-use, efficient and targeting the intended community. This approach, widely used in other fields such as marketing, e-commerce, and design of mobile applications, is still scarcely explored in bioinformatics. In total, around 50 people were actively involved, including internal stakeholders and end-users. In addition to an optimised interface that meets users' needs and expectations, the new version of Expasy provides an up-to-date and accurate description of high-quality resources based on a standardised ontology, allowing to connect functionally-related resources.
    MeSH term(s) Computational Biology ; Databases, Factual ; Software ; User-Computer Interface
    Language English
    Publishing date 2021-04-13
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 186809-3
    ISSN 1362-4962 ; 1362-4954 ; 0301-5610 ; 0305-1048
    ISSN (online) 1362-4962 ; 1362-4954
    ISSN 0301-5610 ; 0305-1048
    DOI 10.1093/nar/gkab225
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1067: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article: Im Gespräch mit Alfred Stockinger, Pflegedirektor am UKR, Birgit Heinze, MSc, Pflegeexpertin ANP-ECMO, Marc Dittrich, MSc, Pflegeexperte ANP-CC

    Stockinger, Alfred / Heinze, Birgit / Dittrich, Marc

    Das Krankenhaus

    2020  Volume 112, Issue 8, Page(s) 692

    Language German
    Document type Article
    ZDB-ID 3262-1
    ISSN 0340-3602
    Database Current Contents Medicine

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ue I Zs.30: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: SPHN - The BioMedIT Network: A Secure IT Platform for Research with Sensitive Human Data.

    Coman Schmid, Diana / Crameri, Katrin / Oesterle, Sabine / Rinn, Bernd / Sengstag, Thierry / Stockinger, Heinz

    Studies in health technology and informatics

    2020  Volume 270, Page(s) 1170–1174

    Abstract: The BioMedIT project is funded by the Swiss government as an integral part of the Swiss Personalized Health Network (SPHN), aiming to provide researchers with access to a secure, powerful and versatile IT infrastructure for doing data-driven research on ... ...

    Abstract The BioMedIT project is funded by the Swiss government as an integral part of the Swiss Personalized Health Network (SPHN), aiming to provide researchers with access to a secure, powerful and versatile IT infrastructure for doing data-driven research on sensitive biomedical data while ensuring data privacy protection. The BioMedIT network gives researchers the ability to securely transfer, store, manage and process sensitive research data. The underlying BioMedIT nodes provide compute and storage capacity that can be used locally or through a federated environment. The network operates under a common Information Security Policy using state-of-the-art security techniques. It utilizes cloud computing, virtualization, compute accelerators (GPUs), big data storage as well as federation technologies to lower computational boundaries for researchers and to guarantee that sensitive data can be processed in a secure and lawful way. Building on existing expertise and research infrastructure at the partnering Swiss institutions, the BioMedIT network establishes a competitive Swiss private-cloud - a secure national infrastructure resource that can be used by researchers of Swiss universities, hospitals and other research institutions.
    MeSH term(s) Big Data ; Cloud Computing ; Computer Security ; Information Storage and Retrieval ; Privacy
    Language English
    Publishing date 2020-06-20
    Publishing country Netherlands
    Document type Journal Article
    ISSN 1879-8365
    ISSN (online) 1879-8365
    DOI 10.3233/SHTI200348
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article ; Online: Pediatric craniospinal irradiation with a short partial-arc VMAT technique for medulloblastoma tumors in dosimetric comparison.

    Pollul, Gerhard / Bostel, Tilman / Grossmann, Sascha / Akbaba, Sati / Karle, Heiko / Stockinger, Marcus / Schmidberger, Heinz

    Radiation oncology (London, England)

    2020  Volume 15, Issue 1, Page(s) 256

    Abstract: Background: This study aimed to contrast four different irradiation methods for pediatric medulloblastoma tumors in a dosimetric comparison regarding planning target volume (PTV) coverage and sparing of organs at risk (OARs).: Methods: In sum 24 ... ...

    Abstract Background: This study aimed to contrast four different irradiation methods for pediatric medulloblastoma tumors in a dosimetric comparison regarding planning target volume (PTV) coverage and sparing of organs at risk (OARs).
    Methods: In sum 24 treatment plans for 6 pediatric patients were realized. Besides the clinical standard of a 3D-conformal radiotherapy (3D-CRT) treatment plan taken as a reference, volumetric modulated arc therapy (VMAT) treatment plans ("VMAT_AVD" vs. "noAVD" vs. "FullArc") were optimized and calculated for each patient. For the thoracic and abdominal region, the short partial-arc VMAT_AVD technique uses an arc setup with reduced arc-length by 100°, using posterior and lateral beam entries. The noAVD uses a half 180° (posterior to lateral directions) and the FullArc uses a full 360° arc setup arrangement. The prescription dose was set to 35.2 Gy.
    Results: We identified a more conformal dose coverage for PTVs and a better sparing of OARs with used VMAT methods. For VMAT_AVD mean dose reductions in organs at risk can be realized, from 16 to 6.6 Gy, from 27.1 to 8.7 Gy and from 8.0 to 1.9 Gy for the heart, the thyroid and the gonads respectively, compared to the 3D-CRT treatment method. In addition we have found out a superiority of VMAT_AVD compared to the noAVD and FullArc trials with lower exposure to low-dose radiation to the lungs and breasts.
    Conclusions: With the short partial-arc VMAT_AVD technique, dose exposures to radiosensitive OARS like the heart, the thyroid or the gonads can be reduced and therefore, maybe the occurrence of late sequelae is less likely. Furthermore the PTV conformity is increased. The advantages of the VMAT_AVD have to be weighed against the potentially risks induced by an increased low dose exposure compared to the 3D-CRT method.
    MeSH term(s) Adolescent ; Cerebellar Neoplasms/radiotherapy ; Child ; Child, Preschool ; Craniospinal Irradiation ; Humans ; Medulloblastoma/radiotherapy ; Radiotherapy Dosage ; Radiotherapy Planning, Computer-Assisted ; Radiotherapy, Intensity-Modulated/methods
    Language English
    Publishing date 2020-11-05
    Publishing country England
    Document type Journal Article
    ISSN 1748-717X
    ISSN (online) 1748-717X
    DOI 10.1186/s13014-020-01690-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article ; Online: Pediatric craniospinal irradiation with a short partial-arc VMAT technique for medulloblastoma tumors in dosimetric comparison

    Gerhard Pollul / Tilman Bostel / Sascha Grossmann / Sati Akbaba / Heiko Karle / Marcus Stockinger / Heinz Schmidberger

    Radiation Oncology, Vol 15, Iss 1, Pp 1-

    2020  Volume 10

    Abstract: Abstract Background This study aimed to contrast four different irradiation methods for pediatric medulloblastoma tumors in a dosimetric comparison regarding planning target volume (PTV) coverage and sparing of organs at risk (OARs). Methods In sum 24 ... ...

    Abstract Abstract Background This study aimed to contrast four different irradiation methods for pediatric medulloblastoma tumors in a dosimetric comparison regarding planning target volume (PTV) coverage and sparing of organs at risk (OARs). Methods In sum 24 treatment plans for 6 pediatric patients were realized. Besides the clinical standard of a 3D-conformal radiotherapy (3D-CRT) treatment plan taken as a reference, volumetric modulated arc therapy (VMAT) treatment plans (“VMAT_AVD” vs. “noAVD” vs. “FullArc”) were optimized and calculated for each patient. For the thoracic and abdominal region, the short partial-arc VMAT_AVD technique uses an arc setup with reduced arc-length by 100°, using posterior and lateral beam entries. The noAVD uses a half 180° (posterior to lateral directions) and the FullArc uses a full 360° arc setup arrangement. The prescription dose was set to 35.2 Gy. Results We identified a more conformal dose coverage for PTVs and a better sparing of OARs with used VMAT methods. For VMAT_AVD mean dose reductions in organs at risk can be realized, from 16 to 6.6 Gy, from 27.1 to 8.7 Gy and from 8.0 to 1.9 Gy for the heart, the thyroid and the gonads respectively, compared to the 3D-CRT treatment method. In addition we have found out a superiority of VMAT_AVD compared to the noAVD and FullArc trials with lower exposure to low-dose radiation to the lungs and breasts. Conclusions With the short partial-arc VMAT_AVD technique, dose exposures to radiosensitive OARS like the heart, the thyroid or the gonads can be reduced and therefore, maybe the occurrence of late sequelae is less likely. Furthermore the PTV conformity is increased. The advantages of the VMAT_AVD have to be weighed against the potentially risks induced by an increased low dose exposure compared to the 3D-CRT method.
    Keywords Pediatric radiation ; Medulloblastoma ; Craniospinal irradiation ; Partial VMAT ; Medical physics. Medical radiology. Nuclear medicine ; R895-920 ; Neoplasms. Tumors. Oncology. Including cancer and carcinogens ; RC254-282
    Subject code 616
    Language English
    Publishing date 2020-11-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Book ; Conference proceedings: Updating international nuclear law

    Stockinger, Heinz

    papers derived from the Conference on the Human Right to a Safe and Healthful Environment and the Responsibilities Under International Law of Operators of Nuclear Facilities, held in Salzburg, Austria, October 20-23, 2005

    2007  

    Event/congress Conference on the Human Right to a Safe and Healthful Environment and the Responsibilities under International Law of Operators of Nuclear Facilities (2005, SalzburgAustria)
    Author's details edited by Heinz Stockinger ... [et al.]
    MeSH term(s) Power Plants/legislation & jurisprudence ; Radioactive Hazard Release/legislation & jurisprudence
    Keywords Europe
    Language English
    Size 509 p. :, ill. ;, 22 cm.
    Publisher NWV Neuer Wissenschaftlicher Verlag
    Publishing place Wien ; Graz
    Document type Book ; Conference proceedings
    Note International conference proceedings.
    ISBN 9783708304496 ; 3708304497 ; 9783830514008 ; 383051400X ; 9789050956802 ; 9050956807
    Database Catalogue of the US National Library of Medicine (NLM)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Book ; Conference proceedings ; Online: First International Conference on e-Science and Grid Computing

    Stockinger, Heinz

    05 - 08 Dec. 2005, [Melbourne, Australia ; proceedings]

    2005  

    Title variant E-science 2005
    Institution International Conference on E-Science and Grid Computing
    Computer Society / Technical Committee on Scalable Computing
    University of Melbourne
    Event/congress International Conference on e-Science and Grid Computing (1, 2005.12.05-08, Melbourne)
    Author's details [sponsored by the IEEE Computer Society's Technical Committee for Scalable Computing and the University of Melbourne. Ed. by Heinz Stockinger ...]
    Language English
    Size Online-Ressource (XIX, 588 S.)
    Publisher IEEE Computer Society
    Publishing place Los Alamitos, Calif. u.a.
    Document type Book ; Conference proceedings ; Online
    ISBN 0769524486 ; 9780769524481
    Database Former special subject collection: coastal and deep sea fishing

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Book ; Conference proceedings ; Online: First International Conference on e-Science and Grid Computing

    Stockinger, Heinz

    05 - 08 Dec. 2005, [Melbourne, Australia ; proceedings]

    2005  

    Title variant E-science 2005
    Institution International Conference on E-Science and Grid Computing
    Computer Society / Technical Committee on Scalable Computing
    University of Melbourne
    Event/congress International Conference on e-Science and Grid Computing (1, 2005.12.05-08, Melbourne)
    Author's details [sponsored by the IEEE Computer Society's Technical Committee for Scalable Computing and the University of Melbourne. Ed. by Heinz Stockinger ...]
    Language English
    Size Online-Ressource (XIX, 588 S.)
    Publisher IEEE Computer Society
    Publishing place Los Alamitos, Calif. u.a.
    Document type Book ; Conference proceedings ; Online
    ISBN 0769524486 ; 9780769524481
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Book ; Conference proceedings: Proceedings / First International Conference on e-Science and Grid Computing : Melbourne, Australia, December 5 - 8, 2005

    Stockinger, Heinz

    2005  

    Title variant E-science 2005
    Institution International Conference on E-Science and Grid Computing
    Computer Society / Technical Committee on Scalable Computing
    University of Melbourne
    Event/congress International Conference on e-Science and Grid Computing (1, 2005.12.05-08, Melbourne)
    Author's details [sponsored by the IEEE Computer Society's Technical Committee for Scalable Computing and the University of Melbourne]. Ed. by Heinz Stockinger
    Keywords Computational grids (Computer systems)
    Language English
    Size XIX, 588 S
    Publisher IEEE Computer Society
    Publishing place Los Alamitos, Calif. u.a.
    Document type Book ; Conference proceedings
    ISBN 0769524486 ; 9780769524481
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top