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Article: Assessment of flow regime alteration in the Krishna River basin

Uday Kumar, Akula / K V, Jayakumar

ISH journal of hydraulic engineering. 2022 Apr. 03, v. 28, no. 2

2022

Abstract: ... the Hydrologic Alteration (HA) along the middle and lower Krishna River Basin. 33 ecological parameters are ... 83. The impact of dams on the Krishna River has shown a typical hydrological alteration ...

Abstract	In the present study, Indicator of Hydrological Alteration (IHA) tool is used to calculate the Hydrologic Alteration (HA) along the middle and lower Krishna River Basin. 33 ecological parameters are evaluated to understand the impact of the dams on the downstream of the ecological instream flow. This study focuses on assessing HA through dam impact periods by differentiating and comparing the discharge data into pre- and post-dam impact periods. Therefore, the data affected by the climate variability are eliminated. The obtained results show that the impact of the Nagarjuna Sagar dam is high with an average HA value of 0.81 among the five dams, and PD Jurala has slightly altered with an average HA value of 0.59. Out of the 33 parameters considered, 11 have alternated highly, with HA values ranging from 0.61 to 0.83. The impact of dams on the Krishna River has shown a typical hydrological alteration which might be the risk to the aquatic species. The output of this study will be helpful to the water managers with sufficient information to make a decision.
Keywords	aquatic organisms ; climate ; decision making ; risk ; rivers ; stream flow ; watersheds
Language	English
Dates of publication	2022-0403
Size	p. 212-218.
Publishing place	Taylor & Francis
Document type	Article
ISSN	2164-3040
DOI	10.1080/09715010.2020.1852979
Database	NAL-Catalogue (AGRICOLA)

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Article: Association of Helicobacter Pylori in Carcinoma Stomach at Maharaja Krishna Chandra Gajapat Medical College: A Prospective Study.

Behera, Amar Kumar / Dash, Manasa Ranjan / Soren, Dhirendra Nath / Nayak, Kedar Nath / Rath, Deba Prasad / Behera, Sudhansu

Cureus

2022 Volume 14, Issue 10, Page(s) e30709

Abstract: Introduction Gastric cancer is the fourth most common type of cancer and the second leading cause of cancer-related death in the world. The etiology of gastric cancer ... ...

Abstract	Introduction Gastric cancer is the fourth most common type of cancer and the second leading cause of cancer-related death in the world. The etiology of gastric cancer includes
Language	English
Publishing date	2022-10-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.30709
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Article ; Online: In Silico Approach to Assessing the Polyphenols from Krishna Tulsi ( Ocimum tenuiflorum L.) as a Keap1/Nrf2 Receptor for the Treatment of Inflammatory Bowel Disease

Satish Kumar / Biswatrish Sarkar

Medical Sciences Forum, Vol 21, Iss 1, p

2023 Volume 13

Abstract: ... with the common polyphenols found in Krishna Tulsi ( Ocimum tenuiflorum L.) such as syringic acid, caffeic acid ...

Abstract	Inflammatory bowel disease is a term used for chronic inflammatory condition that includes two diseases, i.e., ulcerative colitis and Crohn’s disease; both mostly affect the colon, as well as the mouth, oesophagus, stomach, small intestine, and large intestine, respectively. If untreated, they may cause the gut to become more constricted, rupture, produce holes, fistulas, and most alarmingly, colon cancer. One of the key signalling pathways reported to be important in IBD and colon cancer is the Keap1/Nrf2 pathway. According to several studies, Keap1/Nrf2 is also implicated in T-cell differentiation and inflammation; it can block generation of IL-17, Th1 and Th17, and stop the production of various other pro-inflammatory cytokines. Most fruits and vegetables contain polyphenols, which are recognized by their possession of more than one phenolic group. By destroying Keap1, these polyphenols can activate a pathway connected to Nrf2. We have seen continuous improvements in polyphenol extraction and purification, and in research on the molecular mechanism of Keap1/Nrf2 in numerous polyphenol monomers that can control Nrf2, over the past decade. Therefore, molecular docking research was carried out to assess how Keap1/Nrf2 interacted with the common polyphenols found in Krishna Tulsi ( Ocimum tenuiflorum L.) such as syringic acid, caffeic acid, ferulic acid, catechin and epicatechin. Catechin was found to have the lowest binding energy (−8.2 kcal/mol), which indicates the high binding affinity between the chosen receptor and ligand. The contact hydrogen bond includes GLY364; LEU365 and LEU557. To verify these results in IBD, however, more in vitro and in vivo research is necessary.
Keywords	molecular docking ; inflammatory bowel disease ; polyphenols ; Keap1/Nrf2 ; colon cancer ; Medicine ; R
Subject code	610
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Impact of COVID-19 Pandemic on Patients with Non-Communicable Disease: An Observational Cross-Sectional Study at AYUSH Set-Ups of Krishna and Darjeeling District, India.

Varanasi, Roja / Nayak, Debadatta / Kumar, Arvind / Choubey, Gurudev / Chinta, Raveendar / Oberai, Praveen / Khurana, Anil

Complementary medicine research

2022 Volume 30, Issue 2, Page(s) 95–106

Abstract: ... period (October 2020), a cross-sectional study was conducted in the Krishna and Darjeeling district ...

Abstract	Objective: The objective of this study was to determine the impact of COVID-19 in patients suffering from NCDs in terms of their knowledge, awareness, perception about COVID-19, use of AYUSH immune boosters (AIB), and management of chronic condition during the pandemic. Method: During the unlock down period (October 2020), a cross-sectional study was conducted in the Krishna and Darjeeling district of Andhra Pradesh and West Bengal, India. 499 individuals suffering from at least one chronic disease were interviewed using a structured questionnaire. Logistic regression was applied to investigate the relationship of socio-demographic characteristics, AIB, and morbidity with pandemic-related care challenges. Principal component analysis was applied to minimize the dimensionality of factors related to COVID care challenges. Results: 499 individuals were surveyed. 91% identified at least three correct COVID appropriate behaviours. 92.2% considered the coronavirus to be a potential threat (mean ± SD: 5.8 ± 2.6). 44.7% and 55.3% lived with one and 2 or more chronic conditions, respectively. Hypertension alone (27.4%) and diabetes with hypertension (33%) were leading presentations. Out of 499, participants, 88.8% had at least one form of AIB. 52% took Ars. alb. with other AIB and 40% took Ars. alb. alone. Only 9 participants were infected with COVID-19. Conclusion: In the interest of a densely populated country like India, the inclusion of simple and safe AYUSH measures is realistic, ethical, and cost-effective. AYUSH interventions as COVID-19 prophylactic and treatment as well as integrative care of chronic illnesses such as NCDs are suggested.
MeSH term(s)	Humans ; Cross-Sectional Studies ; Pandemics ; COVID-19 ; Noncommunicable Diseases ; Chronic Disease ; India ; Hypertension
Language	English
Publishing date	2022-01-11
Publishing country	Switzerland
Document type	Observational Study ; Journal Article
ZDB-ID	2885931-5
ISSN	2504-2106 ; 2504-2092
ISSN (online)	2504-2106
ISSN	2504-2092
DOI	10.1159/000521904
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Article: Remembering Professor Krishna K. Tewari (1937–2017): A Pioneer in Plant Molecular Biology

Kumar, Dhirendra / Tiwari, Swati / Naithani, Sushma / Govindjee, Govindjee

Current plant biology. 2022 Jan., v. 29

2022

Abstract: Professor Krishna K. Tewari (1937–2017) was a pioneer in plant molecular biology and biochemistry ... and topoisomerase I and II. Krishna Tewari also mentored and trained several young scientists. Here ... Krishna's students, friends, and colleagues from the community of plant biology have put together a tribute ...

Abstract	Professor Krishna K. Tewari (1937–2017) was a pioneer in plant molecular biology and biochemistry. He was a professor and served as the Chairman of the Department of Molecular Biology and Biochemistry at the University of California, Irvine, and was the founder-director of the International Centre for Genetic Engineering and Biotechnology, New Delhi, India. His research was focused on understanding the structure and function(s) of plant mitochondrial and chloroplast genomes, identification of aminoacyl-tRNA in the chloroplast genome, identification, and characterization of the large subunit of RUBISCO, chloroplast DNA polymerase, and topoisomerase I and II. Krishna Tewari also mentored and trained several young scientists. Here, Krishna's students, friends, and colleagues from the community of plant biology have put together a tribute commemorating his memory as a loving human being, a great leader and administrator, and above all an excellent plant biologist.
Keywords	DNA-directed DNA polymerase ; biotechnology ; chloroplast DNA ; chloroplast genome ; humans ; memory ; mitochondria ; molecular biology ; plant biology ; research programs ; ribulose-bisphosphate carboxylase ; California ; India
Language	English
Dates of publication	2022-01
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	2785418-8
ISSN	2214-6628
ISSN	2214-6628
DOI	10.1016/j.cpb.2022.100240
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Article ; Online: Correction for Krishna Kumar et al., Limitations of GCTA as a solution to the missing heritability problem.

Kumar, Siddharth Krishna / Feldman, Marcus W / Rehkopf, David H / Tuljapurkar, Shripad

Proceedings of the National Academy of Sciences of the United States of America

2016 Volume 113, Issue 6, Page(s) E813

Language	English
Publishing date	2016-02-09
Publishing country	United States
Document type	Published Erratum
ZDB-ID	209104-5
ISSN	1091-6490 ; 0027-8424
ISSN (online)	1091-6490
ISSN	0027-8424
DOI	10.1073/pnas.1600634113
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Article ; Online: A Population-Based Cross-Sectional Study of Visual Impairment in West Godavari and Krishna Districts in Andhra Pradesh: Akividu Visual Impairment Study (AVIS).

Marmamula, Srinivas / Yelagondula, Vijay Kumar / Khanna, Rohit C / Banerjee, Saptak / Challa, Rajesh / Yellapragada, Ratnakar / Keeffe, Jill E

Ophthalmic epidemiology

2021 Volume 29, Issue 4, Page(s) 411–416

Abstract: ... in West Godavari and Krishna districts in Andhra Pradesh, India.: Methods: Trained teams visited ...

Abstract	Purpose: To report the prevalence and causes of visual impairment (VI) among those aged ≥40 years in West Godavari and Krishna districts in Andhra Pradesh, India. Methods: Trained teams visited the households in the selected clusters and conducted eye examinations. Presenting visual acuity (PVA) was assessed for distance and near. Torchlight examination was conducted to assess the anterior segment. Non-mydriatic retinal images were also obtained. VI was defined as PVA worse than 6/18 in the better eye. It included Moderate VI (PVA worse than 6/18 to 6/60), Severe VI (PVA worse than 6/60 to 3/60) and Blindness (PVA worse than 3/60). Multiple logistic regression analysis was conducted to assess the risk factors for VI. Results: In total, 2587/3000 (86.2%) participants were examined. Of this, 1406 (54.4%) were women and 1224 (47.3%) had no education. The age- and gender-adjusted prevalence of VI was 12.8% (95% CI: 11.5-14.1). Compared to the 40-49-year age group, the odds of having VI among those aged 50-59 years, 60-69 years and ≥70 years were 2.93 (95% CI: 1.91-4.52), 6.53 (95% CI: 4.31-9.91) and 17.45 (95% CI: 11.50-26.46), respectively. Those respondents who had no education had a higher odds (OR: 1.73; 95% CI: 1.34-2.23) of VI compared to those who were educated. Cataract (62.4%) and uncorrected refractive errors (29.8%) were the leading causes of VI. Over 90% of the VI was due to avoidable causes. Conclusion: VI is a major public health challenge in Andhra Pradesh. Over 90% of this burden is avoidable and can be eliminated by low-cost interventions such as spectacles and cataract surgery.
MeSH term(s)	Adult ; Blindness/epidemiology ; Blindness/etiology ; Cataract/complications ; Cataract/epidemiology ; Cross-Sectional Studies ; Female ; Humans ; India/epidemiology ; Male ; Middle Aged ; Prevalence ; Vision Disorders/complications ; Vision Disorders/epidemiology ; Vision, Low/complications ; Vision, Low/etiology
Language	English
Publishing date	2021-07-22
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1213070-9
ISSN	1744-5086 ; 0928-6586
ISSN (online)	1744-5086
ISSN	0928-6586
DOI	10.1080/09286586.2021.1946829
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Article: Multiparent-Derived, Marker-Assisted Introgression Lines of the Elite Indian Rice Cultivar, 'Krishna Hamsa' Show Resistance against Bacterial Blight and Blast and Tolerance to Drought.

Badri, Jyothi / Lakshmidevi, Gandhudi / JaiVidhya, L R K / Prasad, Madamsetty Srinivasa / Laha, Gouri Shankar / Lakshmi, Vattikutti Jhansi / Isetty, Subhakara Rao / Padmashree, Revadi / Balakrishnan, Divya / Varanasi, Yasaswini Vishnu Priya / Jukanti, Aravind Kumar / Singh, Uma Maheshwar / Singh, Vikas Kumar / Kumar, Arvind / Ram, T / Subba Rao, Lella Venkata / Sundaram, Raman Meenakshi

Plants (Basel, Switzerland)

2022 Volume 11, Issue 5

Abstract: Major biotic stresses viz., bacterial blight (BB) and blast and brown plant hopper (BPH) coupled with abiotic stresses like drought stress, significantly affect rice yields. To address this, marker-assisted intercross (IC) breeding involving multiple ... ...

Abstract	Major biotic stresses viz., bacterial blight (BB) and blast and brown plant hopper (BPH) coupled with abiotic stresses like drought stress, significantly affect rice yields. To address this, marker-assisted intercross (IC) breeding involving multiple donors was used to combine three BB resistance genes-
Language	English
Publishing date	2022-02-25
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2704341-1
ISSN	2223-7747
ISSN	2223-7747
DOI	10.3390/plants11050622
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Article: Hydrological Alterations due to Anthropogenic Activities in Krishna River Basin, India

Kumar, Uday / Jayakumar, K.V

Ecological indicators. 2019 Aug. 20,

2019

Abstract: ... on the hydrology of the middle and lower stretches of the Krishna River over the past sixty years. The Flow Health ... confirmed that the impact of the Nagarjuna Sagar on the Krishna river basin is the highest among the five ... environmental system in the middle and lower Krishna river basin. ...

Abstract	The present study has been taken up to quantify the impacts of the anthropogenic activities on the hydrology of the middle and lower stretches of the Krishna River over the past sixty years. The Flow Health (FH) method which is based on the Range of Variability Approach (RVA) is used to quantify the hydrological alteration (flow changes) of different flow characteristics. The flow characteristics of pre- and post- dam impact periods are compared and evaluated to understand the ecologically sensitive streamflow parameters. The study is primarily focussed on the impact of human activities such as dam constructions. The wet and dry periods are excluded as they are impacted by climate variability. Results of the study confirmed that the impact of the Nagarjuna Sagar on the Krishna river basin is the highest among the five dams studied, with an average FH score of 0.54 and that of PD Jurala dam is the lowest, with an average FH score of 0.65. This study will be beneficial to help restore regional water resources and eco-environmental system in the middle and lower Krishna river basin.
Keywords	anthropogenic activities ; climate ; dams (hydrology) ; environmental indicators ; rivers ; stream flow ; watersheds ; India
Language	English
Dates of publication	2019-0820
Publishing place	Elsevier Ltd
Document type	Article
Note	Pre-press version
ZDB-ID	2036774-0
ISSN	1872-7034 ; 1470-160X
ISSN (online)	1872-7034
ISSN	1470-160X
DOI	10.1016/j.ecolind.2019.105663
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Multiparent-Derived, Marker-Assisted Introgression Lines of the Elite Indian Rice Cultivar, ‘Krishna Hamsa’ Show Resistance against Bacterial Blight and Blast and Tolerance to Drought

Badri, Jyothi / Lakshmidevi, Gandhudi / JaiVidhya, L.R.K. / Prasad, Madamsetty Srinivasa / Laha, Gouri Shankar / Lakshmi, Vattikutti Jhansi / Isetty, Subhakara Rao / Padmashree, Revadi / Balakrishnan, Divya / Varanasi, Yasaswini Vishnu Priya / Jukanti, Aravind Kumar / Singh, Uma Maheshwar / Singh, Vikas Kumar / Kumar, Arvind / Ram, T. / Rao, Lella Venkata Subba / Sundaram, Raman Meenakshi

Plants

2023

Abstract: ... of the elite Indian rice cultivar ‘Krishna Hamsa’. Three cycles of selective intercrossing followed by selfing ...

Abstract	Major biotic stresses viz., bacterial blight (BB) and blast and brown plant hopper (BPH) coupled with abiotic stresses like drought stress, significantly affect rice yields. To address this, marker-assisted intercross (IC) breeding involving multiple donors was used to combine three BB resistance genes—xa5, xa13 and Xa21, two blast resistance genes—Pi9 and Pi54, two BPH resistance genes—Bph20 and Bph21, and four drought tolerant quantitative trait loci (QTL)—qDTY1.1, qDTY2.1, qDTY3.1 and qDTY12.1—in the genetic background of the elite Indian rice cultivar ‘Krishna Hamsa’. Three cycles of selective intercrossing followed by selfing coupled with foreground selection and phenotyping for the target traits resulted in the development of 196 introgression lines (ILs) with a myriad of gene/QTL combinations. Based on the phenotypic reaction, the ILs were classified into seven phenotypic classes of resistance/tolerance to the following: (1) BB, blast and drought—5 ILs; (2) BB and blast—10 ILs; (3) BB and drought—9 ILs; (4) blast and drought—42 ILs; (5) BB—3 ILs; (6) blast—84 ILs; and (7) drought—43 ILs; none of the ILs were resistant to BPH. Positive phenotypic response (resistance) was observed to both BB and blast in 2 ILs, BB in 9 ILs and blast in 64 ILs despite the absence of corresponding R genes. Inheritance of resistance to BB and/or blast in such ILs could be due to the unknown genes from other parents used in the breeding scheme. Negative phenotypic response (susceptibility) was observed in 67 ILs possessing BB-R genes, 9 ILs with blast-R genes and 9 ILs harboring QTLs for drought tolerance. Complex genic interactions and recombination events due to the involvement of multiple donors explain susceptibility in some of the marker positive ILs. The present investigation successfully demonstrates the possibility of rapid development of multiple stress-tolerant/resistant ILs in the elite cultivar background involving multiple donors through selective intercrossing and stringent phenotyping. The 196 ILs in seven ...
Keywords	rice ; market research ; plant diseases ; drought ; breeding
Language	English
Publishing date	2023-01-03T12:53:54Z
Publisher	MDPI
Publishing country	fr
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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