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Article ; Online: Integrating satellite and reanalysis precipitation products for SWAT hydrological simulation in the Jing River Basin, China.

Zhang, Yangkai / Gao, Yang / Xu, Liujia / Liu, Zhengguang / Wu, Lei

Environmental science and pollution research international

2024 Volume 31, Issue 13, Page(s) 20534–20555

Abstract: In hydrological studies, satellite and reanalysis precipitation products are increasingly being used to supplement gauge observation data. This study designed the composite simulation index (COSI), considering two factors: F1 (data accuracy assessment) ... ...

Abstract	In hydrological studies, satellite and reanalysis precipitation products are increasingly being used to supplement gauge observation data. This study designed the composite simulation index (COSI), considering two factors: F1 (data accuracy assessment) and F2 (hydrological simulation performance), to compare the performance of the latest satellite-based and reanalysis-based precipitation products (IMERG, ERA5, ERA5-Land), the prior precipitation products (TRMM, CMADS), and the multi-source weighted-ensemble precipitation (MSWEP). The Soil and Water Assessment Tool (SWAT) model was then applied to compare and analyze the hydrological simulation performance of four preferred products using three data fusion methods including simple model averaging, variance-based weighted averaging, and the latest quantile-based Bayesian model averaging (QBMA). The results can be summarized as follows: (1) Reanalysis products are superior to satellite-based products in terms of F1. However, the satellite-based precipitation products exhibit less BIAS and relatively higher F2, while the MSWEP has relatively high performance on both F1 and F2. (2) Among reanalysis-based precipitation products, CMADS has the best COSI value of 0.53. Although ERA5-Land shows good performance for individual parameters, the comprehensive assessment reveals that ERA5 outperforms ERA5-Land in terms of both F1 and F2. (3) IMERG and TRMM exhibit similar spatiotemporal patterns and similar F1, but IMERG is superior in F2. (4) QBMA outperformed traditional methods in F2, improving the NS coefficient of SWAT model from 0.74 to 0.85. These findings provide a useful reference for analyzing the strengths and limitations of satellite-based and reanalysis precipitation products, and also provide valuable ideas for the combined application of multi-source precipitation products in hydrological studies.
MeSH term(s)	Soil ; Rivers ; Bayes Theorem ; Hydrology ; China
Chemical Substances	Soil
Language	English
Publishing date	2024-02-20
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-024-32482-z
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Jing-Fang powder ethyl acetate extracts attenuate atopic dermatitis by modulating T-cell activity.

Zhao, Ge / Tong, Yue / Xu, Jie / Zhu, Wenjing / Zeng, Jiuseng / Liu, Rong / Luan, Fei / Zeng, Nan

Molecular immunology

2023 Volume 160, Page(s) 133–149

Abstract: Jing-Fang powder ethyl acetate extract (JFEE) and its isolated C (JFEE-C) possess favorable ...

Abstract	Jing-Fang powder ethyl acetate extract (JFEE) and its isolated C (JFEE-C) possess favorable anti-inflammatory and anti-allergic properties; however, their inhibitory effects on T cell activity remain unknown. In vitro, Jurkat T cells and primary mouse CD4
MeSH term(s)	Animals ; Mice ; Dermatitis, Atopic/drug therapy ; Dermatitis, Atopic/chemically induced ; Interleukin-2 ; Powders/adverse effects ; Powders/metabolism ; NF-kappa B/metabolism ; Cytokines/metabolism ; CD4-Positive T-Lymphocytes/metabolism ; Mice, Inbred BALB C ; Plant Extracts/pharmacology
Chemical Substances	Interleukin-2 ; ethyl acetate (76845O8NMZ) ; Powders ; NF-kappa B ; Cytokines ; Plant Extracts
Language	English
Publishing date	2023-07-08
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	424427-8
ISSN	1872-9142 ; 0161-5890
ISSN (online)	1872-9142
ISSN	0161-5890
DOI	10.1016/j.molimm.2023.07.002
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Article: Mechanisms of Cong Rong Shu Jing Compound Effects on Endoplasmic Reticulum Stress in a Rat Model of Parkinson's Disease.

Lin, Yao / Tang, Lanfang / Huang, Peizhen / Liu, Ting / Zhong, Jianan / Xu, Qian / Li, Xiyu / Lin, Youning / Xiao, Shaojian / Cai, Jing

Evidence-based complementary and alternative medicine : eCAM

2020 Volume 2020, Page(s) 1818307

Abstract: This study investigated the effects of the Cong Rong Shu Jing (CRSJ) compound ...

Abstract	This study investigated the effects of the Cong Rong Shu Jing (CRSJ) compound on endoplasmic reticulum stress in a rat model of Parkinson's disease (PD). A total of 40 rats were subcutaneously injected with rotenone-sunflower oil emulsion into the back of the neck to establish a rat model of PD. These PD rats were randomly divided into low-, medium-, and high-dose groups (intragastric administration of 0.5, 1, and 2 g/kg CRSJ, respectively) and a model group (intragastric administration of the solvent; 10 rats per group). Furthermore, 10 rats each were attributed to the control and vehicle groups (both received intragastric administration of the CRSJ solvent, and the vehicle group were injected additionally with sunflower oil alone). A traction test was conducted two times, after the PD model establishment and after 14 days of CRSJ gavage. The numbers of tyrosine hydroxylase- (TH-) positive cells and the dopamine levels in the substantia nigra were assessed using immunohistochemistry and high-performance liquid chromatography, respectively. Western blotting detected the expression levels of
Language	English
Publishing date	2020-05-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	2171158-6
ISSN	1741-4288 ; 1741-427X
ISSN (online)	1741-4288
ISSN	1741-427X
DOI	10.1155/2020/1818307
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Article ; Online: Jing-Fang powder ethyl acetate extracts attenuate atopic dermatitis by modulating T-cell activity

Zhao, Ge / Tong, Yue / Xu, Jie / Zhu, Wenjing / Zeng, Jiuseng / Liu, Rong / Luan, Fei / Zeng, Nan

Molecular Immunology. 2023 Aug., v. 160 p.133-149

2023

Abstract: Jing-Fang powder ethyl acetate extract (JFEE) and its isolated C (JFEE-C) possess favorable ...

Abstract	Jing-Fang powder ethyl acetate extract (JFEE) and its isolated C (JFEE-C) possess favorable anti-inflammatory and anti-allergic properties; however, their inhibitory effects on T cell activity remain unknown. In vitro, Jurkat T cells and primary mouse CD4⁺ T cells were used to explore the regulatory effects of JFEE and JFEE-C as well as their potential mechanisms on activated T cells. Furthermore, T cell-mediated atopic dermatitis (AD) mouse model was established to confirm these inhibitory effects in vivo. The results showed that JFEE and JFEE-C inhibited T cell activation by suppressing the production of interleukin-2 (IL-2) and interferon-gamma (IFN-γ) without showing cytotoxicity. Flow cytometry showed the inhibitory effects of JFEE and JFEE-C on the activation-induced proliferation and apoptosis of T cells. Pretreatment with JFEE and JFEE-C also decreased the expression levels of several surface molecules, including CD69, CD25, and CD40L. Moreover, it was confirmed that JFEE and JFEE-C inhibited T cell activation by downregulating the TGF-β-activated kinase 1 (TAK1)/nuclear kappa-light-chain-enhancer of activated B cells (NF-κB)/mitogen-activated protein kinase (MAPK) signaling pathways. The combination of these extracts with C25–140 intensified the inhibitory effects on IL-2 production and p65 phosphorylation. The oral administration of JFEE and JFEE-C notably weakened AD manifestations, including the infiltration of mast cells and CD4⁺ cells, epidermis and dermis thicknesses, serum levels of immunoglobulin E (IgE) and thymic stromal lymphopoietin (TSLP), and gene expression levels of T helper (Th) cells-related cytokines in vivo. The underlying mechanisms of the inhibitory effects of JFEE and JFEE-C on AD were related to attenuating T cell activity through NF-κB/MAPK pathways. In conclusion, this study suggested that JFEE and JFEE-C exhibited anti-atopic efficacy by attenuating T cell activity and might possess a curative potential for T cell-mediated diseases.
Keywords	CD4-positive T-lymphocytes ; anti-allergic agents ; apoptosis ; atopic dermatitis ; blood serum ; cytotoxicity ; dermis ; ethyl acetate ; flow cytometry ; gene expression ; immunoglobulin E ; interferon-gamma ; interleukin-2 ; mice ; models ; oral administration ; phosphorylation ; protein kinases ; Jing-Fang powder ethyl acetate extracts ; T cell activation ; IL-2 ; NF-κB/MAPK pathways
Language	English
Dates of publication	2023-08
Size	p. 133-149.
Publishing place	Elsevier Ltd
Document type	Article ; Online
ZDB-ID	424427-8
ISSN	1872-9142 ; 0161-5890
ISSN (online)	1872-9142
ISSN	0161-5890
DOI	10.1016/j.molimm.2023.07.002
Database	NAL-Catalogue (AGRICOLA)

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Article: [Medication regularity and potential targets of Professor XU Jing-fan's prescription for treating ulcerative colitis].

Ning, Li-Qin / Ye, Bai / Shen, Hong / Lu, Wei-Min / Xu, Dan-Hua / Yan, Jing / Tan, Chang / Tang, De-Cai

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

2018 Volume 43, Issue 5, Page(s) 1042–1048

Abstract: ... of modern refractory diseases by WHO. Professor XU Jing-fan, a great master of traditional Chinese medicine ...

Abstract	Ulcerative colitis (UC) is a chronic nonspecific inflammation mainly involving rectum and colon mucosa, which seriously affects the health and quality of life of patients, and is listed as one of modern refractory diseases by WHO. Professor XU Jing-fan, a great master of traditional Chinese medicine, has accumulated rich experiences in the treatment of UC. The study collected Professor XU's 77 prescriptions of treating UC, analyzed the frequency of traditional Chinese medicines and there categories, and investigated the medication regularity by the system clustering method. The findings showed that the most frequently used drugs were clearing-heat herbs, which were followed by hemostatic herbs, excreting-dampness herbs, improving-digestion herbs and tonifying-Qi herbs. At the same time, the commonly combined drugs were excavated. Finally, in order to analyze potential molecular targets of the frequently used herbs, GO enrichment analysis and KEGG signal pathway enrichment analysis were performed with bioinformatics analysis tool for molecular mechanism of traditional Chinese medicine (BATMAN-TCM). The results indicated that Chinese herbal compounds may treat UC by activating PPAR-γ pathway and regulating intestinal inflammation. The exact mechanisms shall be verified through subsequent molecular biological experiments.
MeSH term(s)	Colitis, Ulcerative/drug therapy ; Drug Prescriptions ; Drugs, Chinese Herbal/pharmacology ; Humans ; Medicine, Chinese Traditional ; Quality of Life
Chemical Substances	Drugs, Chinese Herbal
Language	Chinese
Publishing date	2018-04-16
Publishing country	China
Document type	Journal Article
ZDB-ID	1004649-5
ISSN	1001-5302 ; 0254-0029
ISSN	1001-5302 ; 0254-0029
DOI	10.19540/j.cnki.cjcmm.2018.0035
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Article ; Online: Mechanisms of Cong Rong Shu Jing Compound Effects on Endoplasmic Reticulum Stress in a Rat Model of Parkinson’s Disease

Yao Lin / Lanfang Tang / Peizhen Huang / Ting Liu / Jianan Zhong / Qian Xu / Xiyu Li / Youning Lin / Shaojian Xiao / Jing Cai

Evidence-Based Complementary and Alternative Medicine, Vol

2020 Volume 2020

Abstract: This study investigated the effects of the Cong Rong Shu Jing (CRSJ) compound ...

Abstract	This study investigated the effects of the Cong Rong Shu Jing (CRSJ) compound on endoplasmic reticulum stress in a rat model of Parkinson's disease (PD). A total of 40 rats were subcutaneously injected with rotenone-sunflower oil emulsion into the back of the neck to establish a rat model of PD. These PD rats were randomly divided into low-, medium-, and high-dose groups (intragastric administration of 0.5, 1, and 2 g/kg CRSJ, respectively) and a model group (intragastric administration of the solvent; 10 rats per group). Furthermore, 10 rats each were attributed to the control and vehicle groups (both received intragastric administration of the CRSJ solvent, and the vehicle group were injected additionally with sunflower oil alone). A traction test was conducted two times, after the PD model establishment and after 14 days of CRSJ gavage. The numbers of tyrosine hydroxylase- (TH-) positive cells and the dopamine levels in the substantia nigra were assessed using immunohistochemistry and high-performance liquid chromatography, respectively. Western blotting detected the expression levels of α-synuclein, endoplasmic reticulum stress pathways-related proteins, cerebral dopamine neurotrophic factor (CDNF), mesencephalic astrocyte-derived neurotrophic factor (MANF), and phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT) pathway-related proteins. Compared with the model group, the number of TH-positive cells in the substantia nigra was increased in the CRSJ groups. The expression levels of α-synuclein and the endoplasmic reticulum stress pathways-associated proteins glucose regulatory protein 78, inositol-requiring enzyme 1, apoptosis signal-regulating kinase 1, phosphorylated c-Jun N-terminal kinase, and caspase-12 were reduced. However, CRSJ administration elevated the expression levels of the neurotrophic factors CDNF and MANF, as well as those of p-PI3K and p-AKT. The CRSJ compound can relieve endoplasmic reticulum stress in PD rats and exerts protective effects in this animal model. These effects may be ...
Keywords	Other systems of medicine ; RZ201-999
Subject code	630
Language	English
Publishing date	2020-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Emerging hot spot analysis and the spatial–temporal trends of NDVI in the Jing River Basin of China

Xu, Bin / Qi, Bin / Ji, Kai / Liu, Zhao / Deng, Lin / Jiang, Ling

Environmental earth sciences. 2022 Jan., v. 81, no. 2

2022

Abstract: ... of the environmental situation. In this study, the NDVI, precipitation, land use and land cover data of the Jing River Basin were ... from the climate changes and the land cover changes discussed. The results show that the NDVI in Jing River Basin ... water conservation and sustainable development of the Jing River Basin. ...

Abstract	As an important indicator of vegetation coverage, the normalized difference vegetation index (NDVI) reflects the changing pattern and evolving trend of the environment. In the Loess Plateau, vegetation plays a critical role in soil and water conservation, which strongly affects the achievement of sustainable development goals. The study of the spatial distribution and temporal trends of NDVI is of great practical importance for the planning of soil and water conservation measures and the evaluation of the environmental situation. In this study, the NDVI, precipitation, land use and land cover data of the Jing River Basin were collected, the emerging hot spot patterns of the NDVI analyzed, the characteristics of spatial distribution and temporal variation of the NDVI in the basin obtained, and the impacts on NDVI from the climate changes and the land cover changes discussed. The results show that the NDVI in Jing River Basin represents a spatial trend of decreasing from northwest to southeast. The emerging hot spot analysis results show that diminishing cold spot, oscillating hot spot and intensifying hot spot are predominant patterns in the basin. The whole basin shows a statistically significant upward trend of high value aggregation of NDVI. The temporal trend of NDVI in the basin varies from − 0.0171 to 0.0185 per year. The increasing trend of vegetation coverage in the basin is statistically significant. The positive correlation between the NDVI and the precipitation mainly observed upstream of the basin reveals that the growth of vegetation in the Loess Plateau is more dependent on the water supply from the precipitation. Land cover transition patterns and the land use patterns also impact the spatial–temporal trends of the vegetation coverage in the basin. The study results may be helpful for the vegetation restoration, soil and water conservation and sustainable development of the Jing River Basin.
Keywords	basins ; climate ; cold ; ecological restoration ; land cover ; land use ; land use and land cover maps ; normalized difference vegetation index ; soil ; sustainable development ; temporal variation ; vegetation ; water conservation ; water supply ; watersheds ; China
Language	English
Dates of publication	2022-01
Size	p. 55.
Publishing place	Springer Berlin Heidelberg
Document type	Article
ZDB-ID	2493699-6
ISSN	1866-6299 ; 1866-6280
ISSN (online)	1866-6299
ISSN	1866-6280
DOI	10.1007/s12665-022-10175-5
Database	NAL-Catalogue (AGRICOLA)

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Article: The Pollution Haven Strikes Back?–Evidence from Air Quality Daily Variation in the Jing-Jin-Ji Region of China

Xu, Jintao / Xie, Lunyu / Chen, Shuai / Dong, Yingwei

Environmental science & policy. 2022 Sept. 19,

2022

Abstract: Pollution havens create environmental inequality issues. China’s recent policy of directing high- pollution firms to migrate out of its capital, Beijing, offers a case of a pollution haven that was mandated, rather than resulting from firms’ responses to ...

Abstract	Pollution havens create environmental inequality issues. China’s recent policy of directing high- pollution firms to migrate out of its capital, Beijing, offers a case of a pollution haven that was mandated, rather than resulting from firms’ responses to environmental regulation. More importantly, it leads to a question that has been less discussed in previous literature: does a pollution haven strike back? After the highly polluting enterprises moved out of Beijing to neighboring Hebei province, Hebei has been blamed for the continuing poor air quality in Beijing, based on a perception that the pollutants emitted in Hebei are being blown back to Beijing. This paper investigates the existence of a pollution haven in Hebei and quantifies the contribution of Hebei’s emissions to Beijing’s air quality. We find that the proportion of output values and the relative concentration of high- pollution industries in Hebei increased when the large-scale out-migration began, while the indicators in Beijing decreased. We also find higher emissions of enterprises in Hebei than their counterparts in Beijing. Together, these findings indicate the existence of a “manmade” pollution haven. Further, based on high-frequency spatial data, we combine an Autoregressive Distributed Lag model and a Spatial Autoregressive Model and decompose the factors that affect Beijing’s air quality into local and regional air-borne transport of pollutants. We find a significant effect of the neighboring cities’ air pollution on Beijing’s air quality. This indicates that the pollution haven indeed struck back. These findings imply the importance of regional policies to control air pollution.
Keywords	air pollution ; air quality ; capital ; environmental law ; issues and policy ; models ; spatial data ; China
Language	English
Dates of publication	2022-0919
Publishing place	Elsevier Ltd
Document type	Article
Note	Pre-press version
ZDB-ID	1454687-5
ISSN	1462-9011
ISSN	1462-9011
DOI	10.1016/j.envsci.2022.09.014
Database	NAL-Catalogue (AGRICOLA)

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Article: Hot paths and sectors of the energy metabolic process in the Jing-Jin-Ji urban agglomeration

Xu, Dongxiao / Zhang, Yan / Yang, Zhifeng / Zheng, Hongmei / Wang, Xinjing

Journal of cleaner production. 2022 Sept. 01, v. 364

2022

Abstract: China's Jing-Jin-Ji urban agglomeration shows exceptionally high urbanization and ...

Abstract	China's Jing-Jin-Ji urban agglomeration shows exceptionally high urbanization and resource utilization problems that require to identify hot paths and sectors of energy metabolism, thus recognizing key links of cleaner production, and supporting energy conservation and emission reduction. In this paper, an energy metabolic network model was built for the urban agglomeration to simulate energy transfers between sectors using ecological network analysis, and path analysis was performed starting from initial production to identify critical paths and sectors. The chain of paths through 0–3 intermediate nodes dominated the energy metabolic processes, becoming the key to diagnosing problems. The critical paths in the urban agglomeration evolved from joint dominance by intra- and inter-city paths to inter-city paths, indicating increasingly coordinated development. Intra-city paths from Beijing's and Tianjin's Industry were always critical, whereas inter-city paths mainly started from Shijiazhuang's, Handan's, Tangshan's or Baoding's Industry; Beijing's, Tianjin's, Shijiazhuang's, Tangshan's and Handan's Industry played export roles, with Beijing's, Tianjin's, and Shijiazhuang's Industry also playing transfer roles and the other sectors (especially Construction) playing import roles. Above results will serve for the agglomeration's cleaner, more sustainable and more coordinated development.
Keywords	biochemical pathways ; energy ; energy conservation ; energy metabolism ; exports ; imports ; industry ; models ; path analysis ; trophic relationships ; urbanization ; China
Language	English
Dates of publication	2022-0901
Publishing place	Elsevier Ltd
Document type	Article
ISSN	0959-6526
DOI	10.1016/j.jclepro.2022.132653
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Time series-based PM2.5 concentration prediction in Jing-Jin-Ji area using machine learning algorithm models

Ma, Xin / Chen, Tengfei / Ge, Rubing / Cui, Caocao / Xu, Fan / Lv, Qi

Heliyon. 2022 Sept., v. 8, no. 9 p.e10691-

2022

Abstract: Globally all countries encounter air pollution problems along their development path. As a significant indicator of air quality, PM₂.₅ concentration has long been proven to be affecting the population's death rate. Machine learning algorithms proven to ... ...

Abstract	Globally all countries encounter air pollution problems along their development path. As a significant indicator of air quality, PM₂.₅ concentration has long been proven to be affecting the population's death rate. Machine learning algorithms proven to outperform traditional statistical approaches are widely used in air pollution prediction. However research on the model selection discussion and environmental interpretation of model prediction results is still scarce and urgently needed to lead the policy making on air pollution control. Our research compared four types of machine learning algorisms LinearSVR, K-Nearest Neighbor, Lasso regression, Gradient boosting by looking into their performance in predicting PM₂.₅ concentrations among different cities and seasons. The results show that the machine learning model is able to forecast the next day PM₂.₅ concentration based on the previous five days' data with better accuracy. The comparative experiments show that based on city level the Gradient Boosting prediction model has better prediction performance with mean absolute error (MAE) of 9 ug/m³ and root mean square error (RMSE) of 10.25-16.76 ug/m³, lower compared with the other three models, and based on season level four models have the best prediction performances in winter time and the worst in summer time. And more importantly the demonstration of models' different performances in each city and each season is of great significance in environmental policy implications.
Keywords	air pollution ; air pollution control ; air quality ; algorithms ; environmental policy ; models ; mortality ; prediction ; summer ; winter ; Jing-Jin-Ji city group ; PM2.5 prediction ; Lasso regression ; Gradient boosting ; Linear SVR ; K-Nearest Neighbor
Language	English
Dates of publication	2022-09
Publishing place	Elsevier Ltd
Document type	Article ; Online
Note	Use and reproduction
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2022.e10691
Database	NAL-Catalogue (AGRICOLA)

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