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Article ; Online: Thanks for the offer: Testing drink offers as predictors of sexual activity.

Hamilton, Hannah R / Armeli, Stephen / Tennen, Howard

Journal of American college health : J of ACH

2022 , Page(s) 1–5

Abstract: Objective: ...

Abstract	Objective:
Language	English
Publishing date	2022-06-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	604907-2
ISSN	1940-3208 ; 0744-8481
ISSN (online)	1940-3208
ISSN	0744-8481
DOI	10.1080/07448481.2022.2086435
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Article ; Online: COVID-19 in college: Risk perception and planned protective behavior.

Hamilton, Hannah R / Peterson, Julie Longua / DeHart, Tracy

Journal of American college health : J of ACH

2022 , Page(s) 1–6

Abstract: Objective: ...

Abstract	Objective:
Language	English
Publishing date	2022-05-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	604907-2
ISSN	1940-3208 ; 0744-8481
ISSN (online)	1940-3208
ISSN	0744-8481
DOI	10.1080/07448481.2022.2071623
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Article ; Online: Behind the Mask of Intensive Care Unit Healthcare Workers.

Wozniak, Hannah / Douflé, Ghislaine / Hamilton, Mika / Santangelo, Erminio / Urner, Martin / Parotto, Matteo / Herridge, Margaret / Dragoi, Laura

American journal of respiratory and critical care medicine

2024

Language	English
Publishing date	2024-03-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	1180953-x
ISSN	1535-4970 ; 0003-0805 ; 1073-449X
ISSN (online)	1535-4970
ISSN	0003-0805 ; 1073-449X
DOI	10.1164/rccm.202402-0350VP
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Article ; Online: Cancer researchers' experiences with and perceptions of research data sharing: Results of a cross-sectional survey.

Hamilton, Daniel G / Page, Matthew J / Everitt, Sarah / Fraser, Hannah / Fidler, Fiona

Accountability in research

2024 , Page(s) 1–28

Abstract: Background: Despite wide recognition of the benefits of sharing research data, public availability rates have not increased substantially in oncology or medicine more broadly over the last decade.: Methods: We surveyed 285 cancer researchers to ... ...

Abstract	Background: Despite wide recognition of the benefits of sharing research data, public availability rates have not increased substantially in oncology or medicine more broadly over the last decade. Methods: We surveyed 285 cancer researchers to determine their prior experience with sharing data and views on known drivers and inhibitors. Results: We found that 45% of respondents had shared some data from their most recent empirical publication, with respondents who typically studied non-human research participants, or routinely worked with human genomic data, more likely to share than those who did not. A third of respondents added that they had previously shared data privately, with 74% indicating that doing so had also led to authorship opportunities or future collaborations for them. Journal and funder policies were reported to be the biggest general drivers toward sharing, whereas commercial interests, agreements with industrial sponsors and institutional policies were the biggest prohibitors. We show that researchers' decisions about whether to share data are also likely to be influenced by participants' desires. Conclusions: Our survey suggests that increased promotion and support by research institutions, alongside greater championing of data sharing by journals and funders, may motivate more researchers in oncology to share their data.
Language	English
Publishing date	2024-02-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	2069334-5
ISSN	1545-5815 ; 0898-9621
ISSN (online)	1545-5815
ISSN	0898-9621
DOI	10.1080/08989621.2024.2308606
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Article ; Online: Too tired to drink? Daily associations of sleep duration and fatigue with own and others' alcohol consumption.

Hamilton, Hannah R / Armeli, Stephen / Tennen, Howard

Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors

2022 Volume 37, Issue 2, Page(s) 267–274

Abstract: Objective: To better understand how sleep is associated with alcohol consumption among college students, the present study tested whether last night's sleep duration and current day fatigue were associated with being around others who were drinking that ...

Abstract	Objective: To better understand how sleep is associated with alcohol consumption among college students, the present study tested whether last night's sleep duration and current day fatigue were associated with being around others who were drinking that night and, if so, with alcohol consumption. Method: College student drinkers ( Results: Participants were less likely to report that they were with others who were drinking on evenings following higher than average sleep duration or greater than average daytime fatigue. In addition, experiencing greater than average daytime fatigue was associated with a lower likelihood of consuming any alcohol and lower levels of alcohol consumption at the daily level. Thus, daytime fatigue may be protective against alcohol consumption through both selection and behavior moderation. Conclusions: Results may be useful in the development of interventions to prevent heavy drinking among college students. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
MeSH term(s)	Humans ; Female ; Adolescent ; Male ; Sleep Duration ; Fatigue/epidemiology ; Ethanol ; Sleep ; Alcohol Drinking/epidemiology ; Universities ; Alcohol Drinking in College
Chemical Substances	Ethanol (3K9958V90M)
Language	English
Publishing date	2022-09-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2101111-4
ISSN	1939-1501 ; 0893-164X
ISSN (online)	1939-1501
ISSN	0893-164X
DOI	10.1037/adb0000882
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Article ; Online: Join the Party: Approval-Contingent Self-Worth, Drinking Motives, and Drinking Alone and With Others.

Hamilton, Hannah R / Armeli, Stephen / Tennen, Howard

Journal of studies on alcohol and drugs

2022 Volume 84, Issue 3, Page(s) 407–415

Abstract: Objective: Research links approval-contingent self-worth to college drinking but has not differentiated social and solitary consumption. High approval-contingent self-worth individuals might drink socially to derive approval.: Method: In a sample of ... ...

Abstract	Objective: Research links approval-contingent self-worth to college drinking but has not differentiated social and solitary consumption. High approval-contingent self-worth individuals might drink socially to derive approval. Method: In a sample of 832 undergraduates, approval-contingent self-worth and drinking motives were measured in an initial questionnaire, and social and solitary consumption were reported daily for 30 days. Results: Results indicated an overall positive association between approval-contingent self-worth and social consumption and positive indirect effects via social and enhancement motivations, but a negative indirect effect via conformity motivation. The association between approval-contingent self-worth and solitary alcohol consumption was nonsignificant because of a negative direct effect counteracted by a positive total indirect effect. Conclusions: Results highlight the importance of drinking motives and of distinguishing between social and solitary consumption.
MeSH term(s)	Humans ; Motivation ; Alcohol Drinking/epidemiology ; Social Behavior ; Alcohol Drinking in College ; Surveys and Questionnaires ; Adaptation, Psychological
Language	English
Publishing date	2022-12-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	2266450-6
ISSN	1938-4114 ; 1934-2683 ; 1937-1888 ; 0096-882X
ISSN (online)	1938-4114 ; 1934-2683
ISSN	1937-1888 ; 0096-882X
DOI	10.15288/jsad.22-00178
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Article ; Online: Psychological distress, non-medical use of prescription medications, and perceived unmet mental health care needs: a cross-sectional study of Ontario students.

Landry, Hannah / Kingsbury, Mila / Hamilton, Hayley A / Colman, Ian

Social psychiatry and psychiatric epidemiology

2023 Volume 58, Issue 10, Page(s) 1483–1492

Abstract: Purpose: The non-medical use of prescription medications among adolescents has become a concerning public health issue. This study assessed the prevalence of the non-medical use of prescription medications in Ontario high school students, and explored ... ...

Abstract	Purpose: The non-medical use of prescription medications among adolescents has become a concerning public health issue. This study assessed the prevalence of the non-medical use of prescription medications in Ontario high school students, and explored the moderating effect of this use on the relationship between psychological distress and unmet mental health needs. Methods: Cross-sectional data for 4896 students, age 14-18, were drawn from the 2019 Ontario Student Drug Use and Health Survey. Psychological distress was measured using the Kessler-6 Distress Scale, unmet mental health needs were defined by self-report (yes/no), and non-prescription medication use was defined by self-reported frequency of use. Using logistic regression, we explored the effect of the non-medical use of prescription medications on the relationship between psychological distress and unmet mental health needs. Results: High proportions of Ontario students reported serious psychological distress (22%), some degree of unmet mental health need (38%), and/or non-medical use of prescription medications (13%). While there were strong associations between psychological distress and unmet mental health need, this association was weaker among those reporting non-medical use of prescription medications (OR = 3.3, 95% CI 1.9-5.7) compared to non-users (OR = 5.6, 95% CI 4.5-7.1). Conclusion: Our findings suggest that Ontario students experiencing distress and using non-prescribed medications are less likely to identify a need for mental health support, highlighting the consequences of apparent self-medication through misuse of prescription medications. To assist in the redirection of adolescent perceptions of healthy coping strategies, population-based educational programming, with targeted promotion of both formal and informal mental health care resources, should be considered.
MeSH term(s)	Adolescent ; Humans ; Ontario/epidemiology ; Cross-Sectional Studies ; Mental Health ; Stress, Psychological/epidemiology ; Stress, Psychological/psychology ; Students/psychology ; Psychological Distress
Language	English
Publishing date	2023-03-17
Publishing country	Germany
Document type	Journal Article
ZDB-ID	623071-4
ISSN	1433-9285 ; 0037-7813 ; 0933-7954
ISSN (online)	1433-9285
ISSN	0037-7813 ; 0933-7954
DOI	10.1007/s00127-023-02450-y
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Zs.A 327: Show issues

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Article ; Online: Comparison of three DREADD agonists acting on Gq-DREADDs in the ventral tegmental area to alter locomotor activity in tyrosine hydroxylase:Cre male and female rats.

Robinson, Hannah L / Nicholson, Katherine L / Shelton, Keith L / Hamilton, Peter J / Banks, Matthew L

Behavioural brain research

2023 Volume 455, Page(s) 114674

Abstract: Rationale: Despite the increasingly pervasive use of chemogenetic tools in preclinical neuroscience research, the in vivo pharmacology of DREADD agonists remains poorly understood. The pharmacological effects of any ligand acting at receptors, ... ...

Abstract	Rationale: Despite the increasingly pervasive use of chemogenetic tools in preclinical neuroscience research, the in vivo pharmacology of DREADD agonists remains poorly understood. The pharmacological effects of any ligand acting at receptors, engineered or endogenous, are influenced by numerous factors including potency, time course, and receptor selectivity. Thus, rigorous comparison of the potency and time course of available DREADD ligands may provide an empirical foundation for ligand selection. Objectives: Compare the behavioral pharmacology of three different DREADD ligands clozapine-N-oxide (CNO), compound 21 (C21), and deschloroclozapine (DCZ) in a locomotor activity assay in tyrosine hydroxylase:cre recombinase (TH:Cre) male and female rats. Methods: Locomotor activity in nine adult TH:Cre Sprague-Dawley rats (5 female, 4 male) was monitored for two hours following administration of d-amphetamine (vehicle, 0.1-3.2 mg/kg, IP), DCZ (vehicle, 0.32-320 µg/kg, IP), CNO (vehicle, 0.32-10 mg/kg), and C21 (vehicle, 0.1-3.2 mg/kg, IP). Behavioral sessions were conducted twice per week prior to and starting three weeks after bilateral intra-VTA hM3Dq DREADD virus injection. Results: d-Amphetamine significantly increased locomotor activity pre- and post-DREADD virus injection. DCZ, CNO, and C21 did not alter locomotor activity pre-DREADD virus injection. There was no significant effect of DCZ, CNO, and C21 on locomotor activity post-DREADD virus injection; however, large individual differences in both behavioral response and receptor expression were observed. Conclusions: Large individual variability was observed in both DREADD agonist behavioral effects and receptor expression. These results suggest further basic research would facilitate the utility of these chemogenetic tools for behavioral neuroscience research.
MeSH term(s)	Animals ; Female ; Male ; Rats ; Clozapine/pharmacology ; Clozapine/analogs & derivatives ; Dextroamphetamine ; Imidazoles ; Ligands ; Locomotion ; Rats, Sprague-Dawley ; Sulfonamides ; Thiophenes ; Tyrosine 3-Monooxygenase/metabolism ; Ventral Tegmental Area/metabolism
Chemical Substances	Clozapine (J60AR2IKIC) ; compound 21 (RC2V4W0EYC) ; deschloroclozapine ; Dextroamphetamine (TZ47U051FI) ; Imidazoles ; Ligands ; Sulfonamides ; Thiophenes ; Tyrosine 3-Monooxygenase (EC 1.14.16.2)
Language	English
Publishing date	2023-09-16
Publishing country	Netherlands
Document type	Comparative Study ; Journal Article
ZDB-ID	449927-x
ISSN	1872-7549 ; 0166-4328
ISSN (online)	1872-7549
ISSN	0166-4328
DOI	10.1016/j.bbr.2023.114674
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Zs.A 1599: Show issues

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Article ; Online: Having permission not to remember: perspectives on interventions for post-traumatic stress disorder in the absence of trauma memory.

May, Hannah / Paskell, Rachel / Davies, Catrin / Hamilton-Giachritsis, Catherine

European journal of psychotraumatology

2022 Volume 13, Issue 1, Page(s) 2055295

Abstract: Background: It is possible for people to have post-traumatic stress disorder (PTSD) without memory of the trauma event, such as in drug-facilitated sexual assault. However, there is little evidence available on treatment provision for this population.!## ...

Abstract	Background: It is possible for people to have post-traumatic stress disorder (PTSD) without memory of the trauma event, such as in drug-facilitated sexual assault. However, there is little evidence available on treatment provision for this population. Objective: This study aimed to address this gap by exploring the experiences of people who have had psychological intervention for PTSD without memories (PwM). Method: Interpretative phenomenological analysis was used to explore the lived experience of nine women with PwM, who had sought psychological assessment/therapy. Participants were recruited via social media and completed semi-structured interviews online/via telephone. Results: Identified themes concerned two broad areas: (i) the challenges of having therapy whilst lacking memories and (ii) what was helpful in therapy. Challenges included: delayed help-seeking; having emotional/sensory reactions in the absence of recognisable triggers; experiencing therapy as more applicable to remembered trauma (vs. unremembered); and difficulty discussing and processing unremembered trauma. However, participants also described helpful aspects of therapy including: feeling safe and supported; working with emotional and sensory forms of experience; having scientific explanations for trauma and memory; and having 'permission' from therapists not to remember. Conclusions: Recommendations for clinicians included: being aware that clients with PwM may have more difficulty accessing treatment and perceive it as less applicable to them; focussing on clients' emotions and sensations (not cognitive memories) in therapy; and supporting clients to develop a more self-compassionate understanding of their experiences and lack of memory, thus supporting them to accept that not remembering is 'permitted'. Highlights: • Having therapy for unremembered trauma involves unique challenges, but aspects of therapy can still be helpful.• Suggested 'dos and don'ts' for therapists include recognising the additional barriers to treatment, focussing on emotions (not memories), and normalising memory loss.
MeSH term(s)	Emotions ; Female ; Humans ; Mental Recall ; Stress Disorders, Post-Traumatic/therapy
Language	English
Publishing date	2022-05-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	2586642-4
ISSN	2000-8066 ; 2000-8066
ISSN (online)	2000-8066
ISSN	2000-8066
DOI	10.1080/20008198.2022.2055295
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Article ; Online: Prevalence and predictors of data and code sharing in the medical and health sciences: systematic review with meta-analysis of individual participant data.

Hamilton, Daniel G / Hong, Kyungwan / Fraser, Hannah / Rowhani-Farid, Anisa / Fidler, Fiona / Page, Matthew J

BMJ (Clinical research ed.)

2023 Volume 382, Page(s) e075767

Abstract: Objectives: To synthesise research investigating data and code sharing in medicine and health to establish an accurate representation of the prevalence of sharing, how this frequency has changed over time, and what factors influence availability.: ... ...

Abstract	Objectives: To synthesise research investigating data and code sharing in medicine and health to establish an accurate representation of the prevalence of sharing, how this frequency has changed over time, and what factors influence availability. Design: Systematic review with meta-analysis of individual participant data. Data sources: Ovid Medline, Ovid Embase, and the preprint servers medRxiv, bioRxiv, and MetaArXiv were searched from inception to 1 July 2021. Forward citation searches were also performed on 30 August 2022. Review methods: Meta-research studies that investigated data or code sharing across a sample of scientific articles presenting original medical and health research were identified. Two authors screened records, assessed the risk of bias, and extracted summary data from study reports when individual participant data could not be retrieved. Key outcomes of interest were the prevalence of statements that declared that data or code were publicly or privately available (declared availability) and the success rates of retrieving these products (actual availability). The associations between data and code availability and several factors (eg, journal policy, type of data, trial design, and human participants) were also examined. A two stage approach to meta-analysis of individual participant data was performed, with proportions and risk ratios pooled with the Hartung-Knapp-Sidik-Jonkman method for random effects meta-analysis. Results: The review included 105 meta-research studies examining 2 121 580 articles across 31 specialties. Eligible studies examined a median of 195 primary articles (interquartile range 113-475), with a median publication year of 2015 (interquartile range 2012-2018). Only eight studies (8%) were classified as having a low risk of bias. Meta-analyses showed a prevalence of declared and actual public data availability of 8% (95% confidence interval 5% to 11%) and 2% (1% to 3%), respectively, between 2016 and 2021. For public code sharing, both the prevalence of declared and actual availability were estimated to be <0.5% since 2016. Meta-regressions indicated that only declared public data sharing prevalence estimates have increased over time. Compliance with mandatory data sharing policies ranged from 0% to 100% across journals and varied by type of data. In contrast, success in privately obtaining data and code from authors historically ranged between 0% and 37% and 0% and 23%, respectively. Conclusions: The review found that public code sharing was persistently low across medical research. Declarations of data sharing were also low, increasing over time, but did not always correspond to actual sharing of data. The effectiveness of mandatory data sharing policies varied substantially by journal and type of data, a finding that might be informative for policy makers when designing policies and allocating resources to audit compliance. Systematic review registration: Open Science Framework doi:10.17605/OSF.IO/7SX8U.
MeSH term(s)	Humans ; Prevalence ; Medicine ; Administrative Personnel ; Biomedical Research ; Information Dissemination
Language	English
Publishing date	2023-07-11
Publishing country	England
Document type	Meta-Analysis ; Systematic Review ; Journal Article
ZDB-ID	1362901-3
ISSN	1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
ISSN (online)	1756-1833
ISSN	0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
DOI	10.1136/bmj-2023-075767
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