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  1. Article ; Online: COVID-19 and Coagulopathy.

    Inoue, Ken-Ichiro / Sagawa, Tomoya / Takano, Hirohisa

    American journal of respiratory cell and molecular biology

    2021  Volume 64, Issue 6, Page(s) 764

    MeSH term(s) Blood Coagulation Disorders ; COVID-19 ; Humans ; Lung ; SARS-CoV-2 ; Thrombosis
    Language English
    Publishing date 2021-03-26
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1025960-0
    ISSN 1535-4989 ; 1044-1549
    ISSN (online) 1535-4989
    ISSN 1044-1549
    DOI 10.1165/rcmb.2020-0588LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2851: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Role of IL-6 in Severe Inflammation.

    Inoue, Ken-Ichiro / Sagawa, Tomoya / Takano, Hirohisa

    American journal of respiratory and critical care medicine

    2020  Volume 203, Issue 1, Page(s) 140–141

    MeSH term(s) Asthma ; COVID-19 ; Humans ; Inflammation ; Interleukin-6 ; SARS-CoV-2
    Chemical Substances Interleukin-6
    Language English
    Publishing date 2020-09-21
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202007-3001LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uh II Zs.80: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Preventing the clinical manifestations and disease progression of coronavirus disease using clinically proven protease inhibitors.

    Sagawa, Tomoya / Inoue, Ken-Ichiro / Takano, Hirohisa

    Critical care (London, England)

    2020  Volume 24, Issue 1, Page(s) 511

    MeSH term(s) Amides ; Betacoronavirus ; COVID-19 ; Coronavirus ; Coronavirus Infections ; Critical Illness ; Disease Progression ; Guanidines ; Humans ; Pandemics ; Pneumonia, Viral ; Protease Inhibitors ; Pyrazines ; SARS-CoV-2
    Chemical Substances Amides ; Guanidines ; Protease Inhibitors ; Pyrazines ; favipiravir (EW5GL2X7E0) ; nafamostat (Y25LQ0H97D)
    Keywords covid19
    Language English
    Publishing date 2020-08-18
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-020-03235-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5517: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  4. Article ; Online: Use of protease inhibitors for the prevention of COVID-19.

    Sagawa, Tomoya / Inoue, Ken-Ichiro / Takano, Hirohisa

    Preventive medicine

    2020  Volume 141, Page(s) 106280

    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; COVID-19/prevention & control ; Female ; Humans ; Male ; Middle Aged ; Pandemics/prevention & control ; Pre-Exposure Prophylaxis ; Protease Inhibitors/administration & dosage ; SARS-CoV-2
    Chemical Substances Protease Inhibitors
    Keywords covid19
    Language English
    Publishing date 2020-10-06
    Publishing country United States
    Document type Letter
    ZDB-ID 184600-0
    ISSN 1096-0260 ; 0091-7435
    ISSN (online) 1096-0260
    ISSN 0091-7435
    DOI 10.1016/j.ypmed.2020.106280
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 878: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  5. Article ; Online: Numerical modeling of the beach process of marine plastics: A probabilistic and diagnostic approach with a particle tracking method.

    Hinata, Hirofumi / Sagawa, Nao / Kataoka, Tomoya / Takeoka, Hidetaka

    Marine pollution bulletin

    2020  Volume 152, Page(s) 110910

    Abstract: A model of the beach process of marine plastics was proposed based on the assumption of the beaching and backwashing flux balance, and its applicability was examined by means of time-invariant linear system analysis and particle tracking experiments with ...

    Abstract A model of the beach process of marine plastics was proposed based on the assumption of the beaching and backwashing flux balance, and its applicability was examined by means of time-invariant linear system analysis and particle tracking experiments with respect to the ratio between the residence time of plastics on a beach (τ
    MeSH term(s) Bathing Beaches ; Environmental Monitoring ; Plastics ; Systems Analysis ; Waste Products/analysis
    Chemical Substances Plastics ; Waste Products
    Language English
    Publishing date 2020-02-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2001296-2
    ISSN 1879-3363 ; 0025-326X
    ISSN (online) 1879-3363
    ISSN 0025-326X
    DOI 10.1016/j.marpolbul.2020.110910
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Post-staining Raman analysis of histological sections following decolorization.

    Akaji, Sakiko / Sagawa, Tomoya / Honda, Akiko / Miyasaka, Natsuko / Sadakane, Kaori / Ichinose, Takamichi / Takano, Hirohisa

    The Analyst

    2022  Volume 147, Issue 20, Page(s) 4473–4479

    Abstract: Hematoxylin and eosin (HE) staining of tissue sections is a powerful tool for observing changes in the tissue structure and is used as the most fundamental and vital technique in histology. However, xenobiotics such as polymers and inorganic or organic ... ...

    Abstract Hematoxylin and eosin (HE) staining of tissue sections is a powerful tool for observing changes in the tissue structure and is used as the most fundamental and vital technique in histology. However, xenobiotics such as polymers and inorganic or organic materials have low dyeability, making it difficult to observe the distribution of materials across tissues. Raman spectroscopy is an advantageous technique for identifying materials in tissues using spectroscopic fingerprints by laser irradiation without staining. In this study, we developed a combined method for morphological observation and Raman spectral acquisition on the identical tissue slide by employing a decolorization step to remove eosin-induced fluorescence in HE-stained samples. Our method eliminated the fluorescence background and allowed the identical-field pathological observation, enabling simultaneous identification of biological responses and materials in tissues.
    MeSH term(s) Eosine Yellowish-(YS) ; Hematoxylin ; Polymers ; Spectrum Analysis, Raman/methods ; Staining and Labeling ; Xenobiotics
    Chemical Substances Polymers ; Xenobiotics ; Eosine Yellowish-(YS) (TDQ283MPCW) ; Hematoxylin (YKM8PY2Z55)
    Language English
    Publishing date 2022-10-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 210747-8
    ISSN 1364-5528 ; 0003-2654
    ISSN (online) 1364-5528
    ISSN 0003-2654
    DOI 10.1039/d2an01138g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2423: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article: Preventing the clinical manifestations and disease progression of coronavirus disease using clinically proven protease inhibitors

    Sagawa, Tomoya / Inoue, Ken-Ichiro / Takano, Hirohisa

    Crit Care

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #720245
    Database COVID19

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  9. Article ; Online: Use of protease inhibitors for the prevention of COVID-19

    Sagawa, Tomoya / Inoue, Ken-ichiro / Takano, Hirohisa

    Preventive Medicine

    2020  Volume 141, Page(s) 106280

    Keywords Public Health, Environmental and Occupational Health ; Epidemiology ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 184600-0
    ISSN 1096-0260 ; 0091-7435
    ISSN (online) 1096-0260
    ISSN 0091-7435
    DOI 10.1016/j.ypmed.2020.106280
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 878: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  10. Article ; Online: Numerical modeling of the beach process of marine plastics: 2. A diagnostic approach with onshore-offshore advection-diffusion equations for buoyant plastics.

    Hinata, Hirofumi / Ohno, Kazuki / Sagawa, Noa / Kataoka, Tomoya / Takeoka, Hidetaka

    Marine pollution bulletin

    2020  Volume 160, Page(s) 111548

    Abstract: A model is proposed for the beach process of buoyant marine plastics, specifically its beaching and backwashing, by introducing beaching and backwashing diffusion coefficients and the onshore-offshore advection-diffusion equations of plastics for the ... ...

    Abstract A model is proposed for the beach process of buoyant marine plastics, specifically its beaching and backwashing, by introducing beaching and backwashing diffusion coefficients and the onshore-offshore advection-diffusion equations of plastics for the upper layers in the beach and adjacent coastal sea. The backwashing diffusion coefficient was estimated from the average residence time of the beached plastics and the beach width, and then the beaching diffusion coefficient was estimated from the flux-balance assumption between the beaching and backwashing fluxes. Finite difference calculations in the staggered-grid system demonstrated that the amount of beached plastics responds as predicted by the linear system analysis when the beach had an exponential decay type of unit impulse response regardless of the ratio between the residence time and the period of beaching flux fluctuation from the nearshore. The condition in which the flux balance assumption holds was also discussed.
    MeSH term(s) Environmental Monitoring ; Plastics ; Systems Analysis ; Waste Products/analysis
    Chemical Substances Plastics ; Waste Products
    Language English
    Publishing date 2020-08-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2001296-2
    ISSN 1879-3363 ; 0025-326X
    ISSN (online) 1879-3363
    ISSN 0025-326X
    DOI 10.1016/j.marpolbul.2020.111548
    Database MEDical Literature Analysis and Retrieval System OnLINE

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