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  1. Article ; Online: Transjugular intrahepatic portosystemic shunt in portal hypertension: How to go further while staying on track?

    Larrue, Hélène / Bureau, Christophe

    Hepatology (Baltimore, Md.)

    2022  Volume 77, Issue 2, Page(s) 344–346

    MeSH term(s) Humans ; Portasystemic Shunt, Transjugular Intrahepatic ; Hypertension, Portal/surgery ; Portal Vein/surgery
    Language English
    Publishing date 2022-10-13
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 604603-4
    ISSN 1527-3350 ; 0270-9139
    ISSN (online) 1527-3350
    ISSN 0270-9139
    DOI 10.1002/hep.32789
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1660: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Prophylactic embolization of large spontaneous portosystemic shunts with transjugular intrahepatic portosystemic shunt (TIPS): A panacea for post-TIPS hepatic encephalopathy?

    Tripathi, Dhiraj / Bureau, Christophe

    Hepatology (Baltimore, Md.)

    2022  Volume 76, Issue 3, Page(s) 551–553

    MeSH term(s) Esophageal and Gastric Varices ; Gastrointestinal Hemorrhage ; Hepatic Encephalopathy/etiology ; Humans ; Portasystemic Shunt, Transjugular Intrahepatic ; Treatment Outcome
    Language English
    Publishing date 2022-04-29
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 604603-4
    ISSN 1527-3350 ; 0270-9139
    ISSN (online) 1527-3350
    ISSN 0270-9139
    DOI 10.1002/hep.32525
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1660: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Reply to: "Comment on 'TIPS prevents further decompensation and improves survival in patients with cirrhosis and portal hypertension in an individual patient data meta-analysis'": Further decompensation should now be used as a clinically relevant outcome.

    Larrue, Hélène / Bureau, Christophe / D'Amico, Gennaro

    Journal of hepatology

    2023  Volume 80, Issue 3, Page(s) e109–e110

    MeSH term(s) Humans ; Liver Cirrhosis ; Hypertension, Portal ; Portasystemic Shunt, Transjugular Intrahepatic ; Treatment Outcome
    Language English
    Publishing date 2023-10-27
    Publishing country Netherlands
    Document type Meta-Analysis ; Letter
    ZDB-ID 605953-3
    ISSN 1600-0641 ; 0168-8278
    ISSN (online) 1600-0641
    ISSN 0168-8278
    DOI 10.1016/j.jhep.2023.10.022
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    Zs.A 2027: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: "Vascular liver diseases: Position paper(s) from the francophone network for vascular liver diseases, the French Association for the Study of the Liver (AFEF), and the European Reference Network on Hepatological Diseases (ERN RARE-LIVER)".

    Plessier, Aurélie / Bureau, Christophe

    Clinics and research in hepatology and gastroenterology

    2020  Volume 44, Issue 4, Page(s) 407–409

    MeSH term(s) Humans ; Liver/blood supply ; Liver Diseases ; Vascular Diseases
    Language English
    Publishing date 2020-04-29
    Publishing country France
    Document type Journal Article ; Practice Guideline
    ZDB-ID 2594333-9
    ISSN 2210-741X ; 2210-7401
    ISSN (online) 2210-741X
    ISSN 2210-7401
    DOI 10.1016/j.clinre.2020.03.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Failure to control variceal bleeding: Definition matters.

    Baiges, Anna / Bureau, Christophe / García-Pagán, Juan Carlos

    Journal of hepatology

    2021  Volume 74, Issue 6, Page(s) 1491–1492

    MeSH term(s) Esophageal and Gastric Varices/diagnosis ; Esophageal and Gastric Varices/etiology ; Gastrointestinal Hemorrhage/diagnosis ; Gastrointestinal Hemorrhage/etiology ; Humans ; Varicose Veins
    Language English
    Publishing date 2021-01-19
    Publishing country Netherlands
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 605953-3
    ISSN 1600-0641 ; 0168-8278
    ISSN (online) 1600-0641
    ISSN 0168-8278
    DOI 10.1016/j.jhep.2021.01.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2027: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Management of Severe and Refractory Ascites.

    Larrue, Hélène / Vinel, Jean Pierre / Bureau, Christophe

    Clinics in liver disease

    2021  Volume 25, Issue 2, Page(s) 431–440

    Abstract: Considering the poor prognosis, severe and refractory ascites is a milestone in cirrhotic patients. Liver transplantation must be considered first. In the case of contraindication to liver transplantation or when the waiting period is estimated to be ... ...

    Abstract Considering the poor prognosis, severe and refractory ascites is a milestone in cirrhotic patients. Liver transplantation must be considered first. In the case of contraindication to liver transplantation or when the waiting period is estimated to be more than 6 months, transjugular intrahepatic portosystemic shunt should be discussed in eligible patients. Regardless of the type of treatment, a careful selection of patients is crucial to avoid further decompensation and specific complications of each treatment.
    MeSH term(s) Ascites/etiology ; Ascites/therapy ; Humans ; Liver Cirrhosis/complications ; Liver Transplantation ; Portasystemic Shunt, Transjugular Intrahepatic ; Treatment Outcome
    Language English
    Publishing date 2021-03-11
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1472315-3
    ISSN 1557-8224 ; 1089-3261
    ISSN (online) 1557-8224
    ISSN 1089-3261
    DOI 10.1016/j.cld.2021.01.010
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    Se 1870: Show issues Location:
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  7. Article ; Online: Transition care to adolescent hepatology in a tertiary center for rare adult-child liver disease.

    Laborde, Nolwenn / Barange, Karl / Girard, Chloé / Marbach, Clothilde / Bureau, Christophe / Broué, Pierre

    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie

    2023  Volume 31, Issue 1, Page(s) 32–37

    Abstract: Aims: This study analyzed the results of a transition program in a patient population with a rare liver disease of pediatric onset.: Method: Data were collected on the clinical course of an adolescent population with a rare disease of pediatric onset ...

    Abstract Aims: This study analyzed the results of a transition program in a patient population with a rare liver disease of pediatric onset.
    Method: Data were collected on the clinical course of an adolescent population with a rare disease of pediatric onset and enrolled in a transition program between 1994 and 2022.
    Results: A total of 238 adolescents (including 34 having undergone a liver transplant on enrolling in the program) were included. Eight patients were lost to follow-up before the first transition consultation and 16 families requested follow-up in an adult hepatology department closer to their home. Overall, 214 initial transition consultations were carried out; 29 patients were subsequently lost to follow-up and 13 switched center. Overall, 15.4 % of the patients enrolled in our program were lost to follow-up. Five adult patients underwent a liver transplantation during this 28-year period. Overall mortality was 3.2 %, graft survival was 91.5 %, and posttransplant survival was 92 %. In total, the current active file represents 183 patients with a median age of 24.3 years (18-51) and a median follow-up period of 5.8 years (6 months to 28 years).
    Conclusion: The implementation of a transition program to adult medicine for adolescents with a rare liver disease should follow the recommendations but must be adapted in line with local practice conditions. This process requires close collaboration between the pediatric and adult medicine teams based on a mutual desire to constantly improve practices and enhance knowledge.
    MeSH term(s) Adult ; Humans ; Child ; Adolescent ; Young Adult ; Middle Aged ; Transitional Care ; Transition to Adult Care ; Gastroenterology ; Rare Diseases ; Liver Diseases/therapy
    Language English
    Publishing date 2023-11-21
    Publishing country France
    Document type Journal Article
    ZDB-ID 1181947-9
    ISSN 1769-664X ; 0929-693X
    ISSN (online) 1769-664X
    ISSN 0929-693X
    DOI 10.1016/j.arcped.2023.08.012
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    Zs.A 3942: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: eG Coated Stents Exhibit Enhanced Endothelial Wound Healing Characteristics.

    Rodriguez-Garcia, Belen / Bureau, Christophe / Barakat, Abdul I

    Cardiovascular engineering and technology

    2021  Volume 12, Issue 5, Page(s) 515–525

    Abstract: Purpose: Despite their widespread use, a significant fraction of coronary stents suffer from in-stent restenosis and stent thrombosis. Stent deployment induces extensive injury to the vascular endothelium. Rapid endothelial wound closure is essential ... ...

    Abstract Purpose: Despite their widespread use, a significant fraction of coronary stents suffer from in-stent restenosis and stent thrombosis. Stent deployment induces extensive injury to the vascular endothelium. Rapid endothelial wound closure is essential for the success of a stenting procedure. A recent study has demonstrated that the BuMA Supreme® sirolimus-eluting stent exhibits particularly attractive strut coverage characteristics. A unique feature of this stent is the presence of a thin brush layer of poly-butyl methacrylate (PBMA), covalently bonded to the stent's cobalt-chromium frame via electro-grafting (eG™). The present study aimed to determine whether the PBMA coating has an effect on endothelial cell wound healing and stent strut coverage.
    Methods: We used an in vitro coronary artery model whose wall consisted of an annular collagen hydrogel and whose luminal surface was lined with a monolayer of endothelial cells. Mechanical wounding of the endothelial lining was preformed prior to deployment of a bare cobalt-chromium stent either with or without the PBMA layer. The migration of fluorescently labeled endothelial cells was monitored automatically over a period of 48 h to determine endothelial wound healing rates.
    Results: Quantitative assessment of endothelial wound healing rates within the simulated arterial model is achievable using automated image analysis. Wound healing is significantly faster (44% faster at 48 h) for stents with the PBMA eG Coating™ compared to bare metal stents.
    Conclusion: The PBMA eG Coating™ has the effect of promoting endothelial wound healing. Future studies will focus on elucidating the mechanistic basis of this observation.
    MeSH term(s) Drug-Eluting Stents ; Endothelial Cells ; Prosthesis Design ; Sirolimus ; Stents ; Treatment Outcome ; Wound Healing
    Chemical Substances Sirolimus (W36ZG6FT64)
    Language English
    Publishing date 2021-05-18
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2543111-0
    ISSN 1869-4098 ; 1869-408X
    ISSN (online) 1869-4098
    ISSN 1869-408X
    DOI 10.1007/s13239-021-00542-x
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  9. Article ; Online: Eosinophils as Drivers of Severe Eosinophilic Asthma: Endotypes or Plasticity?

    Van Hulst, Glenn / Bureau, Fabrice / Desmet, Christophe J

    International journal of molecular sciences

    2021  Volume 22, Issue 18

    Abstract: Asthma is now recognized as a heterogeneous disease, encompassing different phenotypes driven by distinct pathophysiological mechanisms called endotypes. Common phenotypes of asthma, referred to as eosinophilic asthma, are characterized by the presence ... ...

    Abstract Asthma is now recognized as a heterogeneous disease, encompassing different phenotypes driven by distinct pathophysiological mechanisms called endotypes. Common phenotypes of asthma, referred to as eosinophilic asthma, are characterized by the presence of eosinophilia. Eosinophils are usually considered invariant, terminally differentiated effector cells and have become a primary therapeutic target in severe eosinophilic asthma (SEA) and other eosinophil-associated diseases (EADs). Biological treatments that target eosinophils reveal an unexpectedly complex role of eosinophils in asthma, including in SEA, suggesting that "not all eosinophils are equal". In this review, we address our current understanding of the role of eosinophils in asthma with regard to asthma phenotypes and endotypes. We further address the possibility that different SEA phenotypes may involve differences in eosinophil biology. We discuss how these differences could arise through eosinophil "endotyping", viz. adaptations of eosinophil function imprinted during their development, or through tissue-induced plasticity, viz. local adaptations of eosinophil function through interaction with their lung tissue niches. In doing so, we also discuss opportunities, technical challenges, and open questions that, if addressed, might provide considerable benefits in guiding the choice of the most efficient precision therapies of SEA and, by extension, other EADs.
    MeSH term(s) Animals ; Asthma/metabolism ; Eosinophils/metabolism ; Humans ; Immunotherapy/methods
    Language English
    Publishing date 2021-09-21
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms221810150
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  10. Article ; Online: Transjugular intrahepatic portosystemic shunt in patients with cirrhosis: Indications and posttransjugular intrahepatic portosystemic shunt complications in 2020.

    Horhat, Adelina / Bureau, Christophe / Thabut, Dominique / Rudler, Marika

    United European gastroenterology journal

    2021  Volume 9, Issue 2, Page(s) 203–208

    Abstract: Transjugular intrahepatic portosystemic shunt is a percutaneous radiologic-guided procedure that aims to reduce portal hypertension by creating a shunt between the portal venous system and the hepatic venous system. The most common cause of portal ... ...

    Abstract Transjugular intrahepatic portosystemic shunt is a percutaneous radiologic-guided procedure that aims to reduce portal hypertension by creating a shunt between the portal venous system and the hepatic venous system. The most common cause of portal hypertension is liver cirrhosis in Western countries. Two main indications of transjugular intrahepatic portosystemic shunt are validated by randomised controlled studies in patients with cirrhosis and variceal bleeding (salvage transjugular intrahepatic portosystemic shunt, early transjugular intrahepatic portosystemic shunt or rebleeding despite an optimal secondary prophylaxis) or refractory ascites. Careful selection of the patients is crucial in order to prevent posttransjugular intrahepatic portosystemic shunt complications, including liver failure, posttransjugular intrahepatic portosystemic shunt encephalopathy occurrence and cardiac decompensation, for a better long-term outcome. In this review, we will discuss transjugular intrahepatic portosystemic shunt indications in 2020 in patients with cirrhosis and portal hypertension, with a special focus on variceal bleeding and refractory ascites. Then, we will describe transjugular intrahepatic portosystemic shunt-related complications, the contraindications and the current knowledge on patient's selection.
    MeSH term(s) Ascites/etiology ; Contraindications, Procedure ; Gastrointestinal Hemorrhage/etiology ; Humans ; Hypertension, Portal/etiology ; Hypertension, Portal/surgery ; Liver Cirrhosis, Alcoholic/complications ; Liver Cirrhosis, Alcoholic/surgery ; Liver Failure/etiology ; Male ; Middle Aged ; Portasystemic Shunt, Transjugular Intrahepatic/adverse effects ; Postoperative Complications ; Recurrence ; Risk Factors ; Salvage Therapy/adverse effects ; Secondary Prevention
    Language English
    Publishing date 2021-02-23
    Publishing country England
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 2728585-6
    ISSN 2050-6414 ; 2050-6406
    ISSN (online) 2050-6414
    ISSN 2050-6406
    DOI 10.1177/2050640620952637
    Database MEDical Literature Analysis and Retrieval System OnLINE

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