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  1. Article ; Online: Designing N-Confused Metalloporphyrin-Based Covalent Organic Frameworks for Enhanced Electrocatalytic Carbon Dioxide Reduction.

    Ren, Zhixin / Zhao, Bo / Xie, Jing

    Small (Weinheim an der Bergstrasse, Germany)

    2023  Volume 19, Issue 33, Page(s) e2301818

    Abstract: Electrochemical conversion of carbon dioxide ( ... ...

    Abstract Electrochemical conversion of carbon dioxide (CO
    Language English
    Publishing date 2023-04-03
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2168935-0
    ISSN 1613-6829 ; 1613-6810
    ISSN (online) 1613-6829
    ISSN 1613-6810
    DOI 10.1002/smll.202301818
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  2. Article ; Online: Biogas utilization without desulfurization pretreatment in a bioelectrochemical system.

    Xie, Zexiang / Jin, Zhixin / Zhang, Shaohui / Chen, Long

    The Science of the total environment

    2023  Volume 872, Page(s) 162239

    Abstract: Utilizing biogas as a fuel for heating and power generation usually requires desulfurization pretreatment. In this study, the biogas utilization without desulfurization pretreatment in a bioelectrochemical system (BES) was explored. The results showed ... ...

    Abstract Utilizing biogas as a fuel for heating and power generation usually requires desulfurization pretreatment. In this study, the biogas utilization without desulfurization pretreatment in a bioelectrochemical system (BES) was explored. The results showed that the biogas-fueled BES was successfully started up within 36 d and the presence of hydrogen sulfide promoted both methane consumption and electricity generation. The optimal performance (i.e., a methane consumption of 0.523 ± 0.004 mmol/d, a peak voltage of 577 ± 1 mV, a coulomb production of 37.86 ± 0.43C/d, a coulombic efficiency of 9.37 ± 0.06 % and the maximum power density of 2.070 W/m
    MeSH term(s) Biofuels ; Archaea/metabolism ; Electricity ; Bacteria/metabolism ; Methane/metabolism ; Anaerobiosis ; Bioreactors/microbiology
    Chemical Substances Biofuels ; BES (10191-18-1) ; Methane (OP0UW79H66)
    Language English
    Publishing date 2023-02-14
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2023.162239
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 949: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  3. Article ; Online: Ferritin Is Secreted from Primary Cultured Astrocyte in Response to Iron Treatment via TRPML1-Mediated Exocytosis.

    Yu, Xiaoqi / Xiao, Zhixin / Xie, Junxia / Xu, Huamin

    Cells

    2023  Volume 12, Issue 21

    Abstract: Impaired iron homeostasis has been proven to be one of the critical contributors to the pathology of Parkinson's disease (PD). Ferritin is considered an intracellular protein responsible for storing cytosolic iron. Recent studies have found that ferritin ...

    Abstract Impaired iron homeostasis has been proven to be one of the critical contributors to the pathology of Parkinson's disease (PD). Ferritin is considered an intracellular protein responsible for storing cytosolic iron. Recent studies have found that ferritin can be secreted from cells independent of the classical endoplasmic reticulum-Golgi system. However, the precise mechanisms underlying the secretion of ferritin in the brain were not elucidated. In the present study, we demonstrated that the primary cultured astrocytes do have the ability to secrete ferritin, which is enhanced by iron treatment. Increased ferritin secretion was accompanied by increased protein expression of ferritin response to iron stimulation. Further study showed that iron-induced expression and secretion of ferritin could be inhibited by CQ or 3-MA pretreatment. In addition, the knockdown of transient receptor potential mucolipin 1 (TRPML1) antagonized iron-induced ferritin secretion, accompanied by further increased intracellular protein levels of ferritin. Further study demonstrated that ferritin colocalized with LAMP1 in iron-treated astrocytes. On the contrary, ras-associated protein 27a (Rab27a) knockdown further enhanced iron-induced ferritin secretion and decreased intracellular protein levels of ferritin. Furthermore, we also showed that the secretory autophagy protein tripartite motif containing 16 (TRIM16) and sec22b decreased in iron-treated astrocytes. These results suggested that astrocytes might secrete ferritin via TRPML1-mediated exocytosis. This provides new evidence for the mechanisms underlying the secretion of ferritin in primary cultured astrocytes under a high iron environment.
    MeSH term(s) Iron/metabolism ; Ferritins/metabolism ; Astrocytes/metabolism ; Biological Transport ; Exocytosis
    Chemical Substances Iron (E1UOL152H7) ; Ferritins (9007-73-2)
    Language English
    Publishing date 2023-10-25
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells12212519
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  4. Article: Porcine Intestinal Mucosal Peptides Target Macrophage-Modulated Inflammation and Alleviate Intestinal Homeostasis in Dextrose Sodium Sulfate-Induced Colitis in Mice.

    Wang, Yucong / Xie, Zhixin / Wu, Xiaolong / Du, Lei / Chong, Zhengchen / Liu, Rongxu / Han, Jianchun

    Foods (Basel, Switzerland)

    2024  Volume 13, Issue 1

    Abstract: Porcine intestinal mucosal proteins are novel animal proteins that contain large amounts of free amino acids and peptides. Although porcine intestinal mucosal proteins are widely used in animal nutrition, the peptide bioactivities of their enzymatic ... ...

    Abstract Porcine intestinal mucosal proteins are novel animal proteins that contain large amounts of free amino acids and peptides. Although porcine intestinal mucosal proteins are widely used in animal nutrition, the peptide bioactivities of their enzymatic products are not yet fully understood. In the present study, we investigated the effect of porcine intestinal mucosal peptides (PIMP) on the RAW264.7 cell model of LPS-induced inflammation. The mRNA expression of inflammatory factors (interleukin 6, tumor necrosis factor-α, and interleukin-1β) and nitrous oxide levels were all measured by quantitative real-time PCR and cyclooxygenase-2 protein expression measured by Western blot. To investigate the modulating effect of PIMP and to establish a model of dextran sodium sulfate (DSS)-induced colitis in mice, we examined the effects of hematoxylin-eosin staining, myeloperoxidase levels, pro-inflammatory factor mRNA content, tight junction protein expression, and changes in intestinal flora. Nuclear factor κB pathway protein levels were also assessed by Western blot. PIMP has been shown in vitro to control inflammatory responses and prevent the activation of key associated signaling pathways. PIMP at doses of 100 and 400 mg/kg/day also alleviated intestinal inflammatory responses, reduced tissue damage caused by DSS, and improved intestinal barrier function. In addition, PIMP at 400 mg/kg/day successfully repaired the dysregulated gut microbiota and increased short-chain fatty acid levels. These findings suggest that PIMP may positively influence inflammatory responses and alleviate colitis. This study is the first to demonstrate the potential of PIMP as a functional food for the prevention and treatment of colitis.
    Language English
    Publishing date 2024-01-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods13010162
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  5. Article ; Online: Influence of Steric Effects on the Emission Behavior of Pyrene-Based Blue Luminogens.

    Xie, Zhixin / Liu, Wei / Liu, Yiwei / Song, Xinyi / Zheng, Heng / Su, Xiang / Redshaw, Carl / Feng, Xing

    The Journal of organic chemistry

    2024  Volume 89, Issue 3, Page(s) 1681–1691

    Abstract: Pyrene-based derivatives have been widely deployed in organic luminescent materials because of their bright fluorescence, high charge carrier mobility, and facile modification. Nevertheless, the fluorescence output of conventional pyrenes is prone to ... ...

    Abstract Pyrene-based derivatives have been widely deployed in organic luminescent materials because of their bright fluorescence, high charge carrier mobility, and facile modification. Nevertheless, the fluorescence output of conventional pyrenes is prone to quenching upon aggregation due to extensive intermolecular π-π stacking interactions. To address this issue, a set of new
    Language English
    Publishing date 2024-01-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.3c02372
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4473: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  6. Article ; Online: Mitochondrial iron dyshomeostasis and its potential as a therapeutic target for Parkinson's disease.

    Xiao, Zhixin / Wang, Xiaoya / Pan, Xuening / Xie, Junxia / Xu, Huamin

    Experimental neurology

    2023  Volume 372, Page(s) 114614

    Abstract: Abnormal iron accumulation has been implicated in the etiology of Parkinson's disease (PD). Understanding how iron damages dopaminergic neurons in the substantia nigra (SN) of PD is particularly important for developing targeted neurotherapeutic ... ...

    Abstract Abnormal iron accumulation has been implicated in the etiology of Parkinson's disease (PD). Understanding how iron damages dopaminergic neurons in the substantia nigra (SN) of PD is particularly important for developing targeted neurotherapeutic strategies for the disease. However, it is still not fully understood how excess iron contributes to the neurodegeneration of dopaminergic neurons in PD. There has been increased attention on mitochondrial iron dyshomeostasis, iron-induced mitochondrial dysfunction and ferroptosis in PD. Therefore, this review begins with a brief introduction to describe cellular iron metabolism and the dysregulation of iron metabolism in PD. Then we provide an update on how iron is delivered to mitochondria and induces the damage of dopaminergic neurons in PD. In addition, we also summarize new research progress on iron-dependent ferroptosis in PD and mitochondria-localized proteins involved in ferroptosis. This will provide new insight into potential therapeutic strategies targeting mitochondrial iron dysfunction.
    MeSH term(s) Humans ; Parkinson Disease/metabolism ; Iron/metabolism ; Mitochondria/metabolism ; Substantia Nigra/metabolism ; Dopaminergic Neurons/metabolism
    Chemical Substances Iron (E1UOL152H7)
    Language English
    Publishing date 2023-11-23
    Publishing country United States
    Document type Review ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 207148-4
    ISSN 1090-2430 ; 0014-4886
    ISSN (online) 1090-2430
    ISSN 0014-4886
    DOI 10.1016/j.expneurol.2023.114614
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 184: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Isolation and characterization of a cold-tolerant heterotrophic nitrification-aerobic denitrification bacterium and evaluation of its nitrogen-removal efficiency.

    Yang, Jingyu / Xie, Xiuhong / Miao, Yuanying / Dong, Zhixin / Zhu, Bo

    Environmental research

    2023  Volume 242, Page(s) 117674

    Abstract: With a view toward addressing the poor efficiency with which nitrogen is removed from wastewater below 10 °C, in this study, we isolated a novel cold-tolerant heterotrophic nitrification-aerobic denitrification (HN-AD) bacterium from a wetland and ... ...

    Abstract With a view toward addressing the poor efficiency with which nitrogen is removed from wastewater below 10 °C, in this study, we isolated a novel cold-tolerant heterotrophic nitrification-aerobic denitrification (HN-AD) bacterium from a wetland and characterized its nitrogen removal performance and nitrogen metabolic pathway. On the basis of 16S rRNA gene sequencing, this strain was identified as a species of Janthinobacterium, designated J1-1. At 8 °C, strain J1-1 showed excellent removal efficiencies of 89.18% and 68.18% for single-source NH
    MeSH term(s) Nitrification ; Denitrification ; Wastewater ; Nitrogen/metabolism ; RNA, Ribosomal, 16S ; Nitrogen Dioxide ; Aerobiosis ; Bacteria/metabolism ; Nitrites/metabolism
    Chemical Substances Wastewater ; Nitrogen (N762921K75) ; RNA, Ribosomal, 16S ; Nitrogen Dioxide (S7G510RUBH) ; Nitrites
    Language English
    Publishing date 2023-11-28
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2023.117674
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 726: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Covalent Organic Framework Ionomer Steering the CO

    Zhu, Zhejiaji / Zhu, Yuhao / Ren, Zhixin / Liu, Di / Yue, Feiyu / Sheng, Dafei / Shao, Pengpeng / Huang, Xiuying / Feng, Xiao / Yin, An-Xiang / Xie, Jing / Wang, Bo

    Journal of the American Chemical Society

    2024  Volume 146, Issue 2, Page(s) 1572–1579

    Abstract: ... ...

    Abstract CO
    Language English
    Publishing date 2024-01-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.3c11709
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    In stock of ZB MED Bonn / Germany

    Z 4' 55/32: Show issues
    Z 7.3: Show issues

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  9. Article ; Online: Diversity of soil faunal community as influenced by crop straw combined with different synthetic fertilizers in upland purple soil.

    Xie, Xiuhong / Wang, Xuefeng / Dong, Zhixin / Zhu, Bo

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 19306

    Abstract: Soil fauna play a crucial role in sustaining agro-ecosystem functions. Crop straw is recommended for application to agricultural fields to improve soil quality. However, the effects of crop straw combined with different synthetic fertilizers on the soil ... ...

    Abstract Soil fauna play a crucial role in sustaining agro-ecosystem functions. Crop straw is recommended for application to agricultural fields to improve soil quality. However, the effects of crop straw combined with different synthetic fertilizers on the soil faunal community remain unclear, and knowledge regarding purple soil is limited. Using the conserved cytochrome c oxidase I (COI) gene as markers, we examined the responses of the soil faunal community to different fertilization in upland purple soil of southwestern China. The accuracy of the morphological and molecular methods in characterizing soil nematodes was compared. Our results showed that different fertilization treatments significantly changed the soil faunal community structure (Adonis test, R
    MeSH term(s) Animals ; Fertilizers ; Soil/chemistry ; Ecosystem ; Phosphorus/chemistry ; Nematoda/genetics ; China ; Agriculture/methods
    Chemical Substances Fertilizers ; Soil ; Phosphorus (27YLU75U4W)
    Language English
    Publishing date 2022-11-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-23883-6
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  10. Article ; Online: Diversity of soil faunal community as influenced by crop straw combined with different synthetic fertilizers in upland purple soil

    Xiuhong Xie / Xuefeng Wang / Zhixin Dong / Bo Zhu

    Scientific Reports, Vol 12, Iss 1, Pp 1-

    2022  Volume 12

    Abstract: Abstract Soil fauna play a crucial role in sustaining agro-ecosystem functions. Crop straw is recommended for application to agricultural fields to improve soil quality. However, the effects of crop straw combined with different synthetic fertilizers on ... ...

    Abstract Abstract Soil fauna play a crucial role in sustaining agro-ecosystem functions. Crop straw is recommended for application to agricultural fields to improve soil quality. However, the effects of crop straw combined with different synthetic fertilizers on the soil faunal community remain unclear, and knowledge regarding purple soil is limited. Using the conserved cytochrome c oxidase I (COI) gene as markers, we examined the responses of the soil faunal community to different fertilization in upland purple soil of southwestern China. The accuracy of the morphological and molecular methods in characterizing soil nematodes was compared. Our results showed that different fertilization treatments significantly changed the soil faunal community structure (Adonis test, R 2 = 0.43, P = 0.011). Sixteen biomarkers were identified according to LEfSe (linear discriminant analysis effect size). The diversity and species number of soil fauna were closely related to soil organic matter (SOM) and total phosphorus (TP) (P < 0.05). This study indicates that crop straw return can improve the soil fertility and diversity of soil fauna in purple soil. Additionally, the morphological approach and molecular method based on the COI gene can be considered as complementary approaches in characterizing soil nematode community.
    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2022-11-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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