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  1. Article: Analysis of Genetic Polymorphism and Population Genetic Structure of 57 Autosomal InDel Loci in Beichuan Qiang Population.

    Jiang, Chun-Yue / Ma, Hao / Fan, Qing-Wei / Yang, Hui-Ling / Xu, Dong-Dong / Wang, Yun / DU, Bing

    Fa yi xue za zhi

    2023  Volume 38, Issue 6, Page(s) 739–746

    Abstract: ... in AGCU InDel 60 fluorescence detection kit in the Beichuan Qiang population of Sichuan Province and ... individuals from Beichuan Qiang population of Sichuan Province were typing detected by AGCU InDel 60 ... InDel 60 fluorescence detection kit have a good genetic polymorphism in Beichuan Qiang population ...

    Abstract Objectives: To investigate the genetic information of 57 autosomal InDel loci (A-InDels) included in AGCU InDel 60 fluorescence detection kit in the Beichuan Qiang population of Sichuan Province and evaluate its application value in forensic medicine.
    Methods: A total of 200 unrelated healthy individuals from Beichuan Qiang population of Sichuan Province were typing detected by AGCU InDel 60 fluorescence detection kit. Allele frequencies and population genetic parameters of the 57 A-InDels were statistically analyzed and compared with the available data of 26 populations.
    Results: After Bonferroni correction, there was no linkage disequilibrium between the 57 A-InDels, and all loci were in Hardy-Weinberg equilibrium. Except for rs66595817 and rs72085595, the minor allele frequencies of 55 A-InDels were above 0.3. PIC ranged from 0.298 3 to 0.375 0, CDP was 1-2.974 8×10
    Conclusions: The 57 A-InDels in AGCU InDel 60 fluorescence detection kit have a good genetic polymorphism in Beichuan Qiang population of Sichuan Province, which can be used as effective supplemental for individual identification and paternity identification in forensic medicine.
    MeSH term(s) Humans ; Genetics, Population ; Asian People/genetics ; Polymorphism, Genetic ; Gene Frequency ; INDEL Mutation ; China ; Microsatellite Repeats ; Genetic Loci
    Language Chinese
    Publishing date 2023-02-02
    Publishing country China
    Document type Journal Article
    ISSN 1004-5619
    ISSN 1004-5619
    DOI 10.12116/j.issn.1004-5619.2021.511102
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  2. Article ; Online: Ancient DNA reveals a migration of the ancient Di-qiang populations into Xinjiang as early as the early Bronze Age.

    Gao, Shi-Zhu / Zhang, Ye / Wei, Dong / Li, Hong-Jie / Zhao, Yong-Bin / Cui, Yin-Qiu / Zhou, Hui

    American journal of physical anthropology

    2015  Volume 157, Issue 1, Page(s) 71–80

    Abstract: ... studies revealed that the Di-qiang populations from the Hexi Corridor had migrated to eastern Xinjiang and ...

    Abstract Xinjiang is at the crossroads between East and West Eurasia, and it harbors a relatively complex genetic history. In order to better understand the population movements and interactions in this region, mitochondrial and Y chromosome analyses on 40 ancient human remains from the Tianshanbeilu site in eastern Xinjiang were performed. Twenty-nine samples were successfully assigned to specific mtDNA haplogroups, including the west Eurasian maternal lineages of U and W and the east Eurasian maternal lineages of A, C, D, F, G, Z, M7, and M10. In the male samples, two Y chromosome haplogroups, C* and N1 (xN1a, N1c), were successfully assigned. Our mitochondrial and Y-chromosomal DNA analyses combined with the archaeological studies revealed that the Di-qiang populations from the Hexi Corridor had migrated to eastern Xinjiang and admixed with the Eurasian steppe populations in the early Bronze Age.
    MeSH term(s) Anthropology, Physical ; Asian Continental Ancestry Group/genetics ; China ; Chromosomes, Human, Y/genetics ; DNA, Mitochondrial/genetics ; Female ; Human Migration ; Humans ; Male ; Microsatellite Repeats/genetics ; Polymorphism, Single Nucleotide/genetics
    Chemical Substances DNA, Mitochondrial
    Language English
    Publishing date 2015-05
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 219376-0
    ISSN 1096-8644 ; 0002-9483
    ISSN (online) 1096-8644
    ISSN 0002-9483
    DOI 10.1002/ajpa.22690
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  3. Article ; Online: Comparative study of bacterial status from conjunctival sac of the elder Qiang minority and Han people with dry eye in Sichuan, China.

    Zhang, Yue / Liu, Zhi-Rong / Chen, Hui / Dong, Wan-Jiang / Fan, Ying-Chuan / Yu, Hua / Wang, Guang-Jin / Li, Yu-Chan / Cao, Kui

    International journal of ophthalmology

    2012  Volume 5, Issue 3, Page(s) 343–347

    Abstract: Aim: To compare the status of bacteria in the conjunctival sac from the elder Qiang minority and ... Han people with dry eyes in Sichuan, China.: Methods: Total of 54 elder Qiang people with dry eyes ... strains of bacteria were cultured in either Qiang minority or Han c populations with 3 strains ...

    Abstract Aim: To compare the status of bacteria in the conjunctival sac from the elder Qiang minority and Han people with dry eyes in Sichuan, China.
    Methods: Total of 54 elder Qiang people with dry eyes (108 eyes) were examined by cluster sampling. In the similar habitation region of Han people, 80 (160 dry eyes) Han people were analyzed as the control group. The bacteria was separated from the inferior palpebral conjunctiva, then inoculated on blood plate for 48 hours and identified.
    Results: Totally 24 strains of bacteria were cultured in either Qiang minority or Han c populations with 3 strains of them existed in both ethnic groups. The commonest bacteria in conjunctival sac in two ethnic groups were non-pathogenic bacterium. The composition of Corynebacterium in Han people (54.1%) was significantly higher than that in Qiang minority (27.4%) (χ(2)=11.6721, P=0.0006). The percentage of Sphingomonas Paucimobilis in Qiang people was higher than that in Han people (χ(2)=18.6442, P=0.0000). However, there was no significant difference between Qiang minority and Han people either in bacterial positive rate in conjunctival sac, or the composition of bacteria species and strains, or the composition of staphylococcus epidemids between two ethnic populations.
    Conclusion: There was no significant difference of bacterial positive rate in conjunctival sac from the elder of Qiang minority and Han people with dry eye, but the species of bacteria were different.
    Language English
    Publishing date 2012-06-18
    Publishing country China
    Document type Journal Article
    ZDB-ID 2663246-9
    ISSN 2227-4898 ; 2227-4898
    ISSN (online) 2227-4898
    ISSN 2227-4898
    DOI 10.3980/j.issn.2222-3959.2012.03.18
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  4. Article: [Bacterial profiles in conjunctival sac of middle-aged and elderly Qiang with dry eyes and normal eyes].

    Zhang, Yue / Liu, Zhi-rong / Chen, Hui / Fan, Ying-Chuan / Dong, Wan-jiang / Cao, Kui / Wang, Guang-jin / Li, Yu-chan / Yu, Hua

    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition

    2011  Volume 42, Issue 6, Page(s) 811–814

    Abstract: Objective: To compare the bacteria profiles in conjunctival sac of Qiang aged 40 years and over ... in bacterial positive rate in the conjunctival sac between dry eyes and normal eyes of Qiang aged 40 years and ...

    Abstract Objective: To compare the bacteria profiles in conjunctival sac of Qiang aged 40 years and over between those with dry eyes and those with normal eyes.
    Methods: This survey was undertaken with a standardized protocol in Beichuan county. Ophthalmological examinations were performed on 54 individuals with dry eyes (108 eyes) and 52 individuals with normal eyes (104 eyes). The secretion of the inferior palpebral conjunctival sac was embrocated and inoculated on blood plate for 48-72 hours. The bacteria was separated and identified.
    Results: Positive cultural results were found in 57.4% (62/108) of dry eyes and 61.5% (64/104) of normal eyes. The difference was not statistically significant (P=0.540). No gender and occupational differences in positive cultural results were found (P>0.05). Both the dry eyes and normal eyes were dominated by Gram-positive bacteria, with corynebacterium, staphylococcus epidemids and sphingomonas paucimobilis as main bacteria. Samples taken from the dry eyes produced 73 strains bacteria, 52 (83.8%) with a single strain of bacteria and 10 (16.2%) with co-existed strains of bacteria. The samples taken from the normal eyes were more likely to have co-existed strains of bacteria (P=0.000). Of the 87 strains of bacteria, 64.0%, were single strain and 36.0% were coexisted strains. Fifteen species of bacteria were cultivated from the dry eyes, significantly less than the number of species (24) cultivated from the normal eyes (P=0.027).
    Conclusion: There is no difference in bacterial positive rate in the conjunctival sac between dry eyes and normal eyes of Qiang aged 40 years and over. Gram-positive bacteria is the dominant bacteria. Normal eyes are more likely to have multiple coexisted bacteria compared with dry eyes.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Case-Control Studies ; China/ethnology ; Conjunctiva/microbiology ; Corynebacterium/isolation & purification ; Dry Eye Syndromes/microbiology ; Female ; Gram-Positive Bacteria/isolation & purification ; Humans ; Male ; Middle Aged ; Sphingomonas/isolation & purification ; Staphylococcus epidermidis/isolation & purification
    Language Chinese
    Publishing date 2011-11
    Publishing country China
    Document type English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2106840-9
    ISSN 1672-173X
    ISSN 1672-173X
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  5. Article ; Online: Arteriovenous malformation of upper and lower mesenteric arteries.

    Nie, Qiang-Qiang / Zheng, Kai / Yang, Yu-Guang / Liu, Peng / Fan, Xue-Qiang / Ye, Zhi-Dong

    Journal of vascular surgery

    2024  

    Language English
    Publishing date 2024-02-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605700-7
    ISSN 1097-6809 ; 0741-5214
    ISSN (online) 1097-6809
    ISSN 0741-5214
    DOI 10.1016/j.jvs.2024.02.023
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  6. Article ; Online: Vascular malformations in the thighs of identical twin sisters.

    Zheng, Kai / Nie, Qiang-Qiang / Yang, Yu-Guang / Liu, Peng / Fan, Xue-Qiang / Ye, Zhi-Dong

    Journal of vascular surgery. Venous and lymphatic disorders

    2024  , Page(s) 101850

    Language English
    Publishing date 2024-02-14
    Publishing country United States
    Document type Journal Article
    ISSN 2213-3348
    ISSN (online) 2213-3348
    DOI 10.1016/j.jvsv.2024.101850
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  7. Article ; Online: Associations between gut microbiota and three prostate diseases: a bidirectional two-sample Mendelian randomization study.

    Liu, Xiaoyang / Dong, Qiang

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 4019

    Abstract: According to previous observational researches and clinical trials, the gut microbiota is related to prostate diseases. However, the potential association between gut microbiota and prostate disorders is still uncertain. We first identified groups of gut  ...

    Abstract According to previous observational researches and clinical trials, the gut microbiota is related to prostate diseases. However, the potential association between gut microbiota and prostate disorders is still uncertain. We first identified groups of gut microbiota based on the phylum, class, order, family, and genus levels from consortium MiBioGen. And we acquired prostate diseases statistics from the FINNGEN study and PRACTICAL consortium. Next, two-sample Mendelian randomization was used to investigate the potential associations between three prevalent prostate disease and gut microbiota. In addition, we performed a reverse MR analysis and Benjamini-Hochberg (BH) test for further research. We investigated the connection between 196 gut microbiota and three prevalent prostate diseases. We identified 42 nominally significant associations and 2 robust causative links. Upon correction for multiple comparisons using the Benjamini-Hochberg procedure, our analysis revealed a positive correlation between the risk of prostatitis and the presence of the taxonomic order Gastranaerophilales. Conversely, the risk of prostate cancer exhibited an inverse correlation with the presence of the taxonomic class Alphaproteobacteria. Our study revealed the potential association between gut microbiota and prostate diseases. The results may be useful in providing new insights for further mechanistic and clinical studies of prostate diseases.
    MeSH term(s) Male ; Humans ; Gastrointestinal Microbiome/genetics ; Mendelian Randomization Analysis ; Prostate ; Prostatic Diseases ; Prostatic Neoplasms/genetics ; Alphaproteobacteria ; Genome-Wide Association Study
    Language English
    Publishing date 2024-02-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-54293-5
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  8. Article ; Online: Accelerated degradation of micro-pollutant by combined UV and chlorine dioxide: Unexpected inhibition of chlorite formation.

    Wang, Yan / Sun, Wenyu / Dong, Huiyu / Qiang, Zhimin

    Environmental pollution (Barking, Essex : 1987)

    2023  Volume 337, Page(s) 122600

    Abstract: UV/chlorine dioxide ( ... ...

    Abstract UV/chlorine dioxide (ClO
    MeSH term(s) Disinfectants ; Disinfection ; Water Purification ; Oxides/pharmacology ; Oxidation-Reduction ; Chlorine/pharmacology ; Halogenation ; Water Pollutants, Chemical/analysis
    Chemical Substances chlorine dioxide (8061YMS4RM) ; chlorite (Z63H374SB6) ; Disinfectants ; Oxides ; Chlorine (4R7X1O2820) ; Water Pollutants, Chemical
    Language English
    Publishing date 2023-09-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 280652-6
    ISSN 1873-6424 ; 0013-9327 ; 0269-7491
    ISSN (online) 1873-6424
    ISSN 0013-9327 ; 0269-7491
    DOI 10.1016/j.envpol.2023.122600
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  9. Article: Comparative efficiency and safety of potassium competitive acid blockers

    Dong, Yongqi / Xu, Hongyan / Zhang, Zhihuan / Zhou, Zhihang / Zhang, Qiang

    Frontiers in pharmacology

    2024  Volume 14, Page(s) 1304552

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2024-01-11
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1304552
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  10. Article ; Online: Formation and transformation of pre-chlorination-formed disinfection byproducts in drinking water treatment process.

    Cheng, Xiaoyu / Dong, Huiyu / Qiang, Zhimin

    The Science of the total environment

    2023  Volume 904, Page(s) 166241

    Abstract: As pre-chlorination is increasingly adopted in drinking water treatment plant (DWTP), an attractive question emerged: how the disinfection by-products that formed during pre-chlorination (preformed DBPs) would be transformed in the drinking water ... ...

    Abstract As pre-chlorination is increasingly adopted in drinking water treatment plant (DWTP), an attractive question emerged: how the disinfection by-products that formed during pre-chlorination (preformed DBPs) would be transformed in the drinking water treatment process? This study investigated the DBP formation kinetics and molecular characteristics in chlorinated source water, DBP transformation and removal in practical DWTP. It was found that the formation of trihalomethanes (THMs) followed pseudo first-order kinetic model and the intensified Br
    MeSH term(s) Disinfection ; Halogenation ; Drinking Water ; Water Pollutants, Chemical/analysis ; Water Purification ; Trihalomethanes ; Disinfectants
    Chemical Substances Drinking Water ; Water Pollutants, Chemical ; Trihalomethanes ; Disinfectants
    Language English
    Publishing date 2023-08-15
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2023.166241
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