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  1. Article: Development of a video-based evidence synthesis knowledge translation resource: Drawing on a user-centred design approach.

    Deliv, Cristian / Devane, Declan / Putnam, El / Healy, Patricia / Hall, Amanda / Rosenbaum, Sarah / Toomey, Elaine

    Digital health

    2023  Volume 9, Page(s) 20552076231170696

    Abstract: Objectives: We aimed to develop a video animation knowledge translation (KT) resource to explain the purpose, use and importance of evidence synthesis to the public regarding healthcare decision-making.: Methods: We drew on a user-centred design ... ...

    Abstract Objectives: We aimed to develop a video animation knowledge translation (KT) resource to explain the purpose, use and importance of evidence synthesis to the public regarding healthcare decision-making.
    Methods: We drew on a user-centred design approach to develop a spoken animated video (SAV) by conducting two cycles of idea generation, prototyping, user testing, analysis, and refinement. Six researchers identified the initial key messages of the SAV and informed the first draft of the storyboard and script. Seven members of the public provided input on this draft and the key messages through think-aloud interviews, which we used to develop an SAV prototype. Seven additional members of the public participated in think-aloud interviews while watching the video prototype. All members of the public also completed a questionnaire on perceived usefulness, desirability, clarity and credibility. We subsequently synthesised all data to develop the final SAV.
    Results: Researchers identified the initial key messages as 1) the importance of evidence synthesis, 2) what an evidence synthesis is and 3) how evidence synthesis can impact healthcare decision-making. Members of the public rated the initial video prototype as 9/10 for usefulness, 8/10 for desirability, 8/10 for clarity and 9/10 for credibility. Using their guidance and feedback, we produced a three-and-a-half-minute video animation. The video was uploaded on YouTube, has since been translated into two languages, and viewed over 12,000 times to date.
    Conclusions: Drawing on user-centred design methods provided a structured and transparent approach to the development of our SAV. Involving members of the public enhanced the credibility and usefulness of the resource. Future work could explore involving the public from the outset to identify key messages in developing KT resources explaining methodological topics. This study describes the systematic development of a KT resource with limited resources and provides transferrable learnings for others wishing to do similar.
    Language English
    Publishing date 2023-05-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2819396-9
    ISSN 2055-2076
    ISSN 2055-2076
    DOI 10.1177/20552076231170696
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Prioritising Informed Health Choices Key Concepts for those impacted by cancer: a protocol.

    Li, Mengqi / Devane, Declan / Beecher, Claire / Duffy, Austin G / Duggan, Caitriona / Dowling, Maura / Grimes, David Robert / Kennan, Avril / McLoughlin, Sarah / Nsangi, Allen / Oxman, Andrew D / O'Connor, Robert / Stewart, Derek C / Toomey, Elaine / Tierney, Marie

    HRB open research

    2022  Volume 5, Page(s) 55

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2022-08-04
    Publishing country Ireland
    Document type Journal Article
    ISSN 2515-4826
    ISSN (online) 2515-4826
    DOI 10.12688/hrbopenres.13593.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Open science and conflict of interest policies of medical and health sciences journals before and during the COVID-19 pandemic: A repeat cross-sectional study: Open science policies of medical journals.

    Gardener, Antoni D / Hick, Ellen J / Jacklin, Chloe / Tan, Gifford / Cashin, Aidan G / Lee, Hopin / Nunan, David / Toomey, Elaine C / Richards, Georgia C

    JRSM open

    2022  Volume 13, Issue 11, Page(s) 20542704221132139

    Abstract: Objectives: To audit the transparent and open science standards of health and medical sciences journal policies and explore the impact of the COVID-19 pandemic.: Design: Repeat cross-sectional study.: Setting: 19 journals listed in Google Scholar' ... ...

    Abstract Objectives: To audit the transparent and open science standards of health and medical sciences journal policies and explore the impact of the COVID-19 pandemic.
    Design: Repeat cross-sectional study.
    Setting: 19 journals listed in Google Scholar's Top Publications for health and medical sciences.
    Participants: Blood, Cell, Circulation, European Heart Journal, Gastroenterology, Journal of Clinical Oncology, Journal of the American College of Cardiology, Nature Genetics, Nature Medicine, Nature Neuroscience, Neuron, PLoS ONE, Proceedings of the National Academy of Sciences, Science Translational Medicine, The British Medical Journal, The Journal of the American Medical Association, The Lancet, The Lancet Oncology, and The New England Journal of Medicine.
    Main outcome measures: We used the Transparency and Openness Promotion (TOP) guideline and the International Committee of Medical Journal Editors (ICMJE) requirements for disclosing conflicts of interest (COIs) to evaluate journals standards.
    Results: TOP scores slightly improved during the COVID-19 pandemic, from a median of 5 (IQR: 2-12.5) out of a possible 24 points in February 2020 to 7 (IQR: 4-12) in May 2021, but overall, scores were very low at both time points. Journal policies scored highest for their adherence to data transparency and scored lowest for preregistration of study protocols and analysis plans and the submission of replication studies. Most journals fulfilled all ICMJE provisions for reporting COIs before (84%; n  =  16) and during (95%; n  =  18) the COVID-19 pandemic.
    Conclusions: The COVID-19 pandemic has highlighted the importance of practising open science. However, requirements for open science practices in audited policies were overall low, which may impede progress in health and medical research. As key stakeholders in disseminating research, journals should promote a research culture of greater transparency and more robust open science practices.
    Language English
    Publishing date 2022-11-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2762955-7
    ISSN 2054-2704
    ISSN 2054-2704
    DOI 10.1177/20542704221132139
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Limited engagement with transparent and open science standards in the policies of pain journals: a cross-sectional evaluation.

    Cashin, Aidan G / Bagg, Matthew K / Richards, Georgia C / Toomey, Elaine / McAuley, James H / Lee, Hopin

    BMJ evidence-based medicine

    2020  Volume 26, Issue 6, Page(s) 313–319

    Abstract: Scientific progress requires transparency and openness. The ability to critique, replicate and implement scientific findings depends on the transparency of the study design and methods, and the open availability of study materials, data and code. ... ...

    Abstract Scientific progress requires transparency and openness. The ability to critique, replicate and implement scientific findings depends on the transparency of the study design and methods, and the open availability of study materials, data and code. Journals are key stakeholders in supporting transparency and openness. This study aimed to evaluate 10 highest ranked pain journals' authorship policies with respect to their support for transparent and open research practices. Two independent authors evaluated the journal policies (as at 27 May 2019) using three tools: the self-developed Transparency and Openness Evaluation Tool, the Centre for Open Science (COS) Transparency Factor and the International Committee of Medical Journal Editors (ICMJE) requirements for disclosure of conflicts of interest. We found that the journal policies had an overall low level of engagement with research transparency and openness standards. The median COS Transparency Factor score was 3.5 (IQR 2.8) of 29 possible points, and only 7 of 10 journals' stated requirements for disclosure of conflicts of interest aligned fully with the ICMJE recommendations. Improved transparency and openness of pain research has the potential to benefit all that are involved in generating and using research findings. Journal policies that endorse and facilitate transparent and open research practices will ultimately improve the evidence base that informs the care provided for people with pain.
    MeSH term(s) Authorship ; Cross-Sectional Studies ; Humans ; Pain ; Periodicals as Topic ; Policy
    Language English
    Publishing date 2020-01-24
    Publishing country England
    Document type Journal Article
    ISSN 2515-4478
    ISSN (online) 2515-4478
    DOI 10.1136/bmjebm-2019-111296
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Exploring factors that influence the practice of Open Science by early career health researchers: a mixed methods study.

    Zečević, Ksenija / Houghton, Catherine / Noone, Chris / Lee, Hopin / Matvienko-Sikar, Karen / Toomey, Elaine

    HRB open research

    2021  Volume 3, Page(s) 56

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2021-01-18
    Publishing country Ireland
    Document type Journal Article
    ISSN 2515-4826
    ISSN (online) 2515-4826
    DOI 10.12688/hrbopenres.13119.2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Feasibility of an Audit and Feedback Intervention to Facilitate Journal Policy Change Towards Greater Promotion of Transparency and Openness in Sports Science Research.

    Hansford, Harrison J / Cashin, Aidan G / Bagg, Matthew K / Wewege, Michael A / Ferraro, Michael C / Kianersi, Sina / Mayo-Wilson, Evan / Grant, Sean P / Toomey, Elaine / Skinner, Ian W / McAuley, James H / Lee, Hopin / Jones, Matthew D

    Sports medicine - open

    2022  Volume 8, Issue 1, Page(s) 101

    Abstract: Objectives: To evaluate (1) the feasibility of an audit-feedback intervention to facilitate sports science journal policy change, (2) the reliability of the Transparency of Research Underpinning Social Intervention Tiers (TRUST) policy evaluation form, ... ...

    Abstract Objectives: To evaluate (1) the feasibility of an audit-feedback intervention to facilitate sports science journal policy change, (2) the reliability of the Transparency of Research Underpinning Social Intervention Tiers (TRUST) policy evaluation form, and (3) the extent to which policies of sports science journals support transparent and open research practices.
    Methods: We conducted a cross-sectional, audit-feedback, feasibility study of transparency and openness standards of the top 38 sports science journals by impact factor. The TRUST form was used to evaluate journal policies support for transparent and open research practices. Feedback was provided to journal editors in the format of a tailored letter. Inter-rater reliability and agreement of the TRUST form was assessed using intraclass correlation coefficients and the standard error of measurement, respectively. Time-based criteria, fidelity of intervention delivery and qualitative feedback were used to determine feasibility.
    Results: The audit-feedback intervention was feasible based on the time taken to rate journals and provide tailored feedback. The mean (SD) score on the TRUST form (range 0-27) was 2.05 (1.99), reflecting low engagement with transparent and open practices. Inter-rater reliability of the overall score of the TRUST form was moderate [ICC (2,1) = 0.68 (95% CI 0.55-0.79)], with standard error of measurement of 1.17. However, some individual items had poor reliability.
    Conclusion: Policies of the top 38 sports science journals have potential for improved support for transparent and open research practices. The feasible audit-feedback intervention developed here warrants large-scale evaluation as a means to facilitate change in journal policies.
    Registration: OSF ( https://osf.io/d2t4s/ ).
    Language English
    Publishing date 2022-08-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2809942-4
    ISSN 2198-9761 ; 2199-1170
    ISSN (online) 2198-9761
    ISSN 2199-1170
    DOI 10.1186/s40798-022-00496-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: A survey of knowledge, perceptions and use of core outcome sets among clinical trialists.

    Bellucci, Chiara / Hughes, Karen / Toomey, Elaine / Williamson, Paula R / Matvienko-Sikar, Karen

    Trials

    2021  Volume 22, Issue 1, Page(s) 937

    Abstract: Background: Core outcome sets (COS) are standardised sets of outcomes, which represent the minimum outcomes that should be measured and reported in clinical trials. COS can enhance comparability across health trials by reducing heterogeneity of outcome ... ...

    Abstract Background: Core outcome sets (COS) are standardised sets of outcomes, which represent the minimum outcomes that should be measured and reported in clinical trials. COS can enhance comparability across health trials by reducing heterogeneity of outcome measurement and reporting and potentially minimising selective outcome reporting. Examining what researchers involved in trials know and think about COS is essential to increase awareness and promote COS uptake. The aim of this study is therefore to examine clinical trialists' knowledge, perceptions and experiences of COS.
    Methods: An online survey design was used. Participants were clinical trialists, operationalised for the current study as researchers named as the contact person on a trial registered on the International Standard Randomised Controlled Trial Number (ISRCTN) Trial repository between 1 January 2019 and 21 July 2020. Survey items assessed clinical trialists' familiarity with and understanding of COS, along with experiences of COS use and development.
    Results: Of 1913 clinical trialists contacted to participate, 62 (3%) completed the survey. Forty (65%) participants were familiar with COS and, of those familiar with COS, 21 (55%) had been involved in a trial that used a COS. Of clinical trialists who used COS in a trial(s), less than half (n = 9, 41%) reported that all COS outcomes were used. The main barriers to using COS are poor knowledge about COS (n = 43, 69%) and difficulties identifying relevant COS (n = 42, 68%). Clinical trialists also reported perceptions of COS as restrictive and often containing too many outcomes. The main enablers to using COS are clear understanding (n = 51, 82%) and perceived importance of COS (n = 44, 71%).
    Conclusions: Enhancing clinical trialists' use of all COS outcomes is needed to reduce outcome heterogeneity and enhance comparability across trial findings. Enhancing awareness of COS importance among researchers and funders is needed to ensure that COS are developed and used by clinical trialists. Education and training may further promote awareness and understanding of COS.
    MeSH term(s) Humans ; Outcome Assessment, Health Care
    Language English
    Publishing date 2021-12-19
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2040523-6
    ISSN 1745-6215 ; 1468-6694 ; 1468-6708
    ISSN (online) 1745-6215 ; 1468-6694
    ISSN 1468-6708
    DOI 10.1186/s13063-021-05891-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Priority III: top 10 rapid review methodology research priorities identified using a James Lind Alliance Priority Setting Partnership.

    Beecher, Claire / Toomey, Elaine / Maeso, Beccy / Whiting, Caroline / Stewart, Derek C / Worrall, Andrew / Elliott, Jim / Smith, Maureen / Tierney, Theresa / Blackwood, Bronagh / Maguire, Teresa / Kampman, Melissa / Ling, Benny / Gill, Catherine / Healy, Patricia / Houghton, Catherine / Booth, Andrew / Garritty, Chantelle / Thomas, James /
    Tricco, Andrea C / Burke, Nikita N / Keenan, Ciara / Devane, Declan

    Journal of clinical epidemiology

    2022  Volume 151, Page(s) 151–160

    Abstract: Objectives: A rapid review is a form of evidence synthesis considered a resource-efficient alternative to the conventional systematic review. Despite a dramatic rise in the number of rapid reviews commissioned and conducted in response to the ... ...

    Abstract Objectives: A rapid review is a form of evidence synthesis considered a resource-efficient alternative to the conventional systematic review. Despite a dramatic rise in the number of rapid reviews commissioned and conducted in response to the coronavirus disease 2019 pandemic, published evidence on the optimal methods of planning, doing, and sharing the results of these reviews is lacking. The Priority III study aimed to identify the top 10 unanswered questions on rapid review methodology to be addressed by future research.
    Study design and setting: A modified James Lind Alliance Priority Setting Partnership approach was adopted. This approach used two online surveys and a virtual prioritization workshop with patients and the public, reviewers, researchers, clinicians, policymakers, and funders to identify and prioritize unanswered questions.
    Results: Patients and the public, researchers, reviewers, clinicians, policymakers, and funders identified and prioritized the top 10 unanswered research questions about rapid review methodology. Priorities were identified throughout the entire review process, from stakeholder involvement and formulating the question, to the methods of a systematic review that are appropriate to use, through to the dissemination of results.
    Conclusion: The results of the Priority III study will inform the future research agenda on rapid review methodology. We hope this will enhance the quality of evidence produced by rapid reviews, which will ultimately inform decision-making in the context of healthcare.
    Language English
    Publishing date 2022-08-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639306-8
    ISSN 1878-5921 ; 0895-4356
    ISSN (online) 1878-5921
    ISSN 0895-4356
    DOI 10.1016/j.jclinepi.2022.08.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: What are the most important unanswered research questions on rapid review methodology? A James Lind Alliance research methodology Priority Setting Partnership: the Priority III study protocol.

    Beecher, Claire / Toomey, Elaine / Maeso, Beccy / Whiting, Caroline / Stewart, Derek C / Worrall, Andrew / Elliott, Jim / Smith, Maureen / Tierney, Theresa / Blackwood, Bronagh / Maguire, Teresa / Kampman, Melissa / Ling, Benny / Gravel, Christopher / Gill, Catherine / Healy, Patricia / Houghton, Catherine / Booth, Andrew / Garritty, Chantelle /
    Thomas, James / Tricco, Andrea C / Burke, Nikita N / Keenan, Ciara / Westmore, Matthew / Devane, Declan

    HRB open research

    2021  Volume 4, Page(s) 80

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2021-11-18
    Publishing country Ireland
    Document type Journal Article
    ISSN 2515-4826
    ISSN (online) 2515-4826
    DOI 10.12688/hrbopenres.13321.2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Investigating group-based classes ('weaning workshops') to support complementary infant feeding in Irish primary care settings: a cross-sectional survey.

    Flannery, Caragh / Shea, Caroline / O'Brien, Yvonne / O'Halloran, Joanne / Matvienko-Sikar, Karen / Kelly, Colette / Toomey, Elaine

    Public health nutrition

    2022  , Page(s) 1–12

    Abstract: Objective: This study aims to (1) investigate current practice regarding 'weaning workshops' to support complementary infant feeding delivered within Irish primary care, (2) explore the experiences and opinions of community dietitians regarding optimal ... ...

    Abstract Objective: This study aims to (1) investigate current practice regarding 'weaning workshops' to support complementary infant feeding delivered within Irish primary care, (2) explore the experiences and opinions of community dietitians regarding optimal content and modes of delivery of weaning workshops and (3) identify the key factors to be considered in the development and implementation of weaning workshops delivered within primary care.
    Design: Cross-sectional survey.
    Setting: Irish primary care.
    Participants: Forty-seven community-based dietitians.
    Results: Sixteen dietitians reported that workshops were run in their area with variable frequency, with ten reporting that workshops were never run in their area. Participants reported that mostly mothers of medium socio-economic status (SES) attended weaning workshops when infants were aged between 4 and 7 months, and that feedback from workshop attendees was predominantly positive. Dietitians identified that key factors to be considered in future development and delivery of weaning workshops are (1) workshop characteristics such as content, timing and venue, (2) organisational characteristics such as availability of resources and multidisciplinary involvement and (3) attendee characteristics such as SES.
    Conclusions: This study highlights substantial variability regarding provision of weaning workshops in Ireland, and a lack of standardisation regarding the provider, content and frequency of workshops where workshops are being delivered. The study also provides unique insights into the experiences and opinions of primary care community dietitians regarding the development and delivery of weaning workshops in terms of optimal content and delivery options. These perspectives will make a valuable contribution given the dearth of evidence in this area internationally.
    Language English
    Publishing date 2022-03-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 1436024-x
    ISSN 1475-2727 ; 1368-9800
    ISSN (online) 1475-2727
    ISSN 1368-9800
    DOI 10.1017/S1368980022000477
    Database MEDical Literature Analysis and Retrieval System OnLINE

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