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Article ; Online: The 'eternal' dilemma of OPCABG versus ONCABG continues: superior, equal, inferior or just different?

Lorusso, Roberto / Bari, Gabor / Di Mauro, Michele / Mariani, Silvia

Journal of cardiovascular medicine (Hagerstown, Md.)

2022 Volume 23, Issue 8, Page(s) 559–560

MeSH term(s)	Coronary Artery Bypass ; Coronary Artery Disease ; Humans
Language	English
Publishing date	2022-07-29
Publishing country	United States
Document type	Editorial ; Comment
ZDB-ID	2223461-5
ISSN	1558-2035 ; 1558-2027
ISSN (online)	1558-2035
ISSN	1558-2027
DOI	10.2459/JCM.0000000000001335
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Article ; Online: The confidence in the results of physiotherapy systematic reviews in the musculoskeletal field is not increasing over time: a meta-epidemiological study using AMSTAR 2 tool.

Ferri, Nicola / Ravizzotti, Elisa / Bracci, Alessandro / Carreras, Giulia / Pillastrini, Paolo / Di Bari, Mauro

Journal of clinical epidemiology

2024 Volume 169, Page(s) 111303

Abstract: Objectives: To assess the confidence in the results of systematic reviews on the effectiveness of physiotherapy for musculoskeletal conditions in the past 10 years and to analyze trends and factors associated.: Methods: This is a metaepidemiological ... ...

Abstract	Objectives: To assess the confidence in the results of systematic reviews on the effectiveness of physiotherapy for musculoskeletal conditions in the past 10 years and to analyze trends and factors associated. Methods: This is a metaepidemiological study on systematic reviews (SRs) with meta-analysis of randomized controlled trials (RCTs). MEDLINE, Cochrane Database of Systematic Reviews, CINAHL, and PEDro were searched for SRs of RCT on physiotherapy interventions for musculoskeletal disorders from December 2012 to December 2022. Two researchers independently screened the records based on the inclusion criteria; a random sample of 100 studies was selected, and each journal, author, and study variable was extracted. The methodological quality of SRs was independently assessed with the AMSTAR 2 tool. Any disagreement was solved by consensus. Results: The confidence in SRs results was critically low in 90% of the studies, and it did not increase over time. Cochrane reviews are predominantly represented in the higher AMSTAR 2 confidence levels, with a statistically significant difference compared to non-Cochrane reviews. The last author's H-index is the only predictor of higher confidence among the variables analyzed (OR 1.04; 95% CI: 1.01, 1.06). Conclusion: The confidence in SRs results is unacceptably low. Given the relevance of musculoskeletal disorders and the impact of evidence synthesis on the clinical decision-making process, there is an urgent need to improve the quality of secondary research by adopting more rigorous methods.
Language	English
Publishing date	2024-02-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	639306-8
ISSN	1878-5921 ; 0895-4356
ISSN (online)	1878-5921
ISSN	0895-4356
DOI	10.1016/j.jclinepi.2024.111303
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Article ; Online: Looking for a needle in a haystack: an older diabetic man with cheiroarthropathy loses an insulin pen needle in subcutaneous tissue.

Iacomelli, Iacopo / Giulietti, Chiara / Di Bari, Mauro

Aging clinical and experimental research

2020 Volume 33, Issue 6, Page(s) 1725–1728

MeSH term(s)	Diabetes Mellitus, Type 2/complications ; Humans ; Insulin ; Male ; Subcutaneous Tissue
Chemical Substances	Insulin
Language	English
Publishing date	2020-09-05
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2104785-6
ISSN	1720-8319 ; 1594-0667
ISSN (online)	1720-8319
ISSN	1594-0667
DOI	10.1007/s40520-020-01692-z
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Article: Cardiac Surgery in Nonagenarians Following the TAVI/TMVI Era: A Multicenter 23-Year Comparative Analysis.

Nasso, Giuseppe / Santarpino, Giuseppe / Di Bari, Nicola / Fattouch, Khalil / Condello, Ignazio / Moscarelli, Marco / Del Giglio, Mauro / Paparella, Domenico / Lamarra, Mauro / Savini, Carlo / Coppola, Roberto / Fiorani, Vinicio / Speziale, Giuseppe

Journal of clinical medicine

2023 Volume 12, Issue 6

Abstract: Background: Studies reporting on the outcome of 90-year-old patients undergoing cardiac surgery are scant in literature; and currently, those regarding the implementation of trans-catheter techniques number even fewer.: Methods: We compared patients ... ...

Abstract	Background: Studies reporting on the outcome of 90-year-old patients undergoing cardiac surgery are scant in literature; and currently, those regarding the implementation of trans-catheter techniques number even fewer. Methods: We compared patients aged >89 years operated on between 1998 and 2008 at 8 Italian cardiac surgery centers, with patients of the same age operated on between 2009 and 2021. All of the patients were operated on with "open" surgery, with the exclusion of percutaneous valve repair/implantation procedures. Results: The patients of the two groups (group 98-08-127 patients, and group 09-21-101 patients) had comparable preoperative risk factors in terms of the LogEuroSCORE (98-08: 21.3 ± 6.1 vs. 09-21: 20.9 ± 11.1, Conclusions: Accurate pre-, intra-, and post-operative evaluation/management to reduce biological impacts facilitate significant improvements in the outcomes in nonagenarian patients when compared to the results recorded in previous years.
Language	English
Publishing date	2023-03-10
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm12062177
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Article ; Online: Manipulation under Anesthesia versus Non-Surgical Treatment for Patients with Frozen Shoulder Contracture Syndrome: A Systematic Review.

Salomon, Mattia / Pastore, Chiara / Maselli, Filippo / Di Bari, Mauro / Pellegrino, Raffaello / Brindisino, Fabrizio

International journal of environmental research and public health

2022 Volume 19, Issue 15

Abstract: Purpose: To investigate the efficacy of manipulation under anesthesia (MUA) compared to other non-surgical therapeutic strategies for patients with frozen shoulder contracture syndrome (FSCS). Methods: A systematic review of literature was conducted. A ... ...

Abstract	Purpose: To investigate the efficacy of manipulation under anesthesia (MUA) compared to other non-surgical therapeutic strategies for patients with frozen shoulder contracture syndrome (FSCS). Methods: A systematic review of literature was conducted. A literature search was performed in MEDLINE, EMBASE, PEDro, Cochrane Central Library and Scopus. Only randomized controlled trials were included and assessed for critical appraisal through the Cochrane Collaborations tools. Results: Five randomized controlled trials were included. The overall risk of bias (RoB) was high in 4 out of 5 of the included studies. MUA was found to be not superior in terms of reduction of pain and improvement of function when compared to cortisone injections with hydrodilatation (mean regression coefficient MUA −2.77 vs. injection −2.75; 95% CI (−1.11 to 1.15)) and home exercise (mean difference 95% CI: 0.2 (−0.64 to 1.02)) in the short term (3 months), and cortisone injections with hydrodilatation (mean regression coefficient MUA 3.13 vs. injection 3.23; 95% CI (−0.90 to 1.11)) in the long term (>6 months). Moreover, if compared to structured physiotherapy, MUA highlighted a higher Oxford Shoulder Score at final 1-year follow up (mean difference 95% CI: 1.05 (−1.28 to 3.39); p = 0.38). Similar results were obtained for disability, with statistically no significant long-term (>12 months) differences between MUA and home exercise (mean difference 95% CI: 0 (−3.2 to 3.2)) or structured physiotherapy (mean difference 95% CI: −0.50 (−5.70 to 4.70); p = 0.85)). Only two trials reported adverse events. Conclusions: This review suggested that limited and inconsistent evidence currently exists on the efficacy of MUA compared to other non-surgical strategies in the management of patients with FSCS. Future research should focus on clinical trials with higher methodological quality.
MeSH term(s)	Anesthesia ; Bursitis/therapy ; Contracture/therapy ; Cortisone ; Humans ; Physical Therapy Modalities
Chemical Substances	Cortisone (V27W9254FZ)
Language	English
Publishing date	2022-08-07
Publishing country	Switzerland
Document type	Journal Article ; Review ; Systematic Review
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph19159715
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Article: Extensive Testing May Reduce COVID-19 Mortality: A Lesson From Northern Italy.

Di Bari, Mauro / Balzi, Daniela / Carreras, Giulia / Onder, Graziano

Frontiers in medicine

2020 Volume 7, Page(s) 402

Abstract: The effects of different COVID-19 swab testing policies in Italy need investigation. We examined the relationship between the number of COVID-19 swab tests (per 10,000 population) performed from February 24 through March 27 and 7-day lagged COVID-19 ... ...

Abstract	The effects of different COVID-19 swab testing policies in Italy need investigation. We examined the relationship between the number of COVID-19 swab tests (per 10,000 population) performed from February 24 through March 27 and 7-day lagged COVID-19 mortality (per 10,000 population) in four regions of northern Italy. Lombardy, Piedmont, and initially, also Emilia-Romagna, which followed recommendations for limiting swab testing to symptomatic subjects requiring hospitalization, had a much steeper increase in mortality with increasing number of tests performed than Veneto, which applied a policy of broader testing. The relationship between tests performed and mortality declined in Emilia-Romagna in coincidence with a substantial increase in the number of tests performed on March 18. When the cumulative number of tests performed was regressed linearly toward lagged mortality in Lombardy and Veneto, the slope of the regression was 133 in Veneto and 10.4 tests per one death in Lombardy. These findings suggest that the strategy adopted in Veneto, similar to that in South Korea, was effective in containing COVID-19 epidemics and should be applied in other regions of Italy and countries in Europe.
Keywords	covid19
Language	English
Publishing date	2020-07-14
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2775999-4
ISSN	2296-858X
ISSN	2296-858X
DOI	10.3389/fmed.2020.00402
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Article ; Online: Extensive Testing May Reduce COVID-19 Mortality

Di Bari, Mauro / Balzi, Daniela / Carreras, Giulia / Onder, Graziano

Frontiers in Medicine

A Lesson From Northern Italy

2020 Volume 7

Keywords	covid19
Publisher	Frontiers Media SA
Publishing country	ch
Document type	Article ; Online
ZDB-ID	2775999-4
ISSN	2296-858X
ISSN	2296-858X
DOI	10.3389/fmed.2020.00402
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Article ; Online: The influence of central pain modulation on postoperative outcomes after shoulder surgery: A systematic review.

Innocenti, Tiziano / Ristori, Diego / Galantini, Patrizia / Testa, Marco / Bari, Mauro Di

Acta orthopaedica et traumatologica turcica

2021 Volume 55, Issue 3, Page(s) 227–234

Abstract: Objective: The aim of this study was to systematically review whether the altered central pain modulation has a significant influence on post-surgical outcomes in patients undergoing shoulder surgery due to musculoskeletal disorders.: Methods: A ... ...

Abstract	Objective: The aim of this study was to systematically review whether the altered central pain modulation has a significant influence on post-surgical outcomes in patients undergoing shoulder surgery due to musculoskeletal disorders. Methods: A systematic search of MEDLINE, PEDro, and EMBASE was conducted without time restriction, including observational prognostic studies. Quality in Prognostic Studies Tool was adopted for critical appraisal, and a qualitative synthesis was undertaken. Two authors independently performed study selection, data extraction, and risk of bias assessment; any disagreement was resolved by a third author. A review protocol is published in the PROSPERO registry (CRD42019122303). The data regarding the potential predictors and outcome measures were obtained from the studies. Results: 11 prospective cohort studies were appraised. Overall, 952 patients were included with a sample size that ranged from 20 to 314. Studies included both arthroscopy and open surgery and presented low to moderate ROB. The prognostic factors investigated were depression, psychological distress, anxiety, catastrophizing, fear avoidance beliefs, self-efficacy and quantitative sensory testing. Only avoidance behaviors and self-efficacy were significantly related to post-surgical pain and function at 12 months after surgery. Conclusion: Fear avoidance beliefs and inadequate coping strategies seem to be the most correlated factors with the worst pain and function scores. Surgeons and physical therapists should look for patients with signs of altered central pain modulation before surgery as they might be at risk of unfavorable outcome. Level of evidence: Level II, Therapeutic Study.
MeSH term(s)	Adaptation, Psychological ; Avoidance Learning ; Fear/psychology ; Humans ; Musculoskeletal Diseases/surgery ; Pain Perception ; Pain, Postoperative/psychology ; Shoulder Pain/etiology ; Shoulder Pain/psychology ; Surgical Procedures, Operative/adverse effects
Language	English
Publishing date	2021-05-28
Publishing country	Turkey
Document type	Journal Article ; Systematic Review
ISSN	2589-1294
ISSN (online)	2589-1294
DOI	10.5152/j.aott.2021.20125
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Article ; Online: Manipulation under Anesthesia versus Non-Surgical Treatment for Patients with Frozen Shoulder Contracture Syndrome

Mattia Salomon / Chiara Pastore / Filippo Maselli / Mauro Di Bari / Raffaello Pellegrino / Fabrizio Brindisino

International Journal of Environmental Research and Public Health, Vol 19, Iss 9715, p

A Systematic Review

2022 Volume 9715

Abstract	Purpose: To investigate the efficacy of manipulation under anesthesia (MUA) compared to other non-surgical therapeutic strategies for patients with frozen shoulder contracture syndrome (FSCS). Methods: A systematic review of literature was conducted. A literature search was performed in MEDLINE, EMBASE, PEDro, Cochrane Central Library and Scopus. Only randomized controlled trials were included and assessed for critical appraisal through the Cochrane Collaborations tools. Results: Five randomized controlled trials were included. The overall risk of bias (RoB) was high in 4 out of 5 of the included studies. MUA was found to be not superior in terms of reduction of pain and improvement of function when compared to cortisone injections with hydrodilatation (mean regression coefficient MUA −2.77 vs. injection −2.75; 95% CI (−1.11 to 1.15)) and home exercise (mean difference 95% CI: 0.2 (−0.64 to 1.02)) in the short term (3 months), and cortisone injections with hydrodilatation (mean regression coefficient MUA 3.13 vs. injection 3.23; 95% CI (−0.90 to 1.11)) in the long term (>6 months). Moreover, if compared to structured physiotherapy, MUA highlighted a higher Oxford Shoulder Score at final 1-year follow up (mean difference 95% CI: 1.05 (−1.28 to 3.39); p = 0.38). Similar results were obtained for disability, with statistically no significant long-term (>12 months) differences between MUA and home exercise (mean difference 95% CI: 0 (−3.2 to 3.2)) or structured physiotherapy (mean difference 95% CI: −0.50 (−5.70 to 4.70); p = 0.85)). Only two trials reported adverse events. Conclusions: This review suggested that limited and inconsistent evidence currently exists on the efficacy of MUA compared to other non-surgical strategies in the management of patients with FSCS. Future research should focus on clinical trials with higher methodological quality.
Keywords	adhesive capsulitis ; frozen shoulder ; frozen shoulder contracture syndrome ; manipulation under anesthesia ; physiotherapy ; systematic review ; Medicine ; R
Subject code	610
Language	English
Publishing date	2022-08-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
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Article ; Online: Predictors of physical frailty improvement in older patients enrolled in a multidisciplinary cardiac rehabilitation program.

Baldasseroni, Samuele / Silverii, Maria Vittoria / Herbst, Andrea / Orso, Francesco / Di Bari, Mauro / Pratesi, Alessandra / Burgisser, Costanza / Ungar, Andrea / Marchionni, Niccolò / Fattirolli, Francesco

Heart and vessels

2023 Volume 38, Issue 8, Page(s) 1056–1064

Abstract: Cardiac rehabilitation (CR) improves clinical and functional recovery in older patients after acute cardiac syndromes, whose outcome is influenced by cardiac disease severity, but also by comorbidity and frailty. The aim of the study was to analyze the ... ...

Abstract	Cardiac rehabilitation (CR) improves clinical and functional recovery in older patients after acute cardiac syndromes, whose outcome is influenced by cardiac disease severity, but also by comorbidity and frailty. The aim of the study was to analyze the predictors of physical frailty improvement during the CR program. Data were collected in all patients aged > 75 years consecutively admitted from 1 January to December 2017 to our CR, consisting of 5-day-per-week of 30-min session of biking or calisthenics on alternate days for 4 weeks. Physical frailty was measured with short physical performance battery (SPPB) at the entry and the end of CR. Outcome was represented by an increase of at least 1 point in the SPPB score from baseline to the end of the CR program. In our study population of 100 patients, mean age 81 years, we demonstrated that a strong predictor of improvement in SPPB score was the poorer performance in the test at baseline; for Δ-1 point of score, we registered an OR 2.50 (95% CI = 1.64-3.85; p = 0.001) of probability to improve the physical performance at the end of CR. Interestingly those patients with worse performance at SPPB balance and chair standing task showed greater probability of ameliorating their physical frailty profile at the end of CR. Our data strongly suggest that CR program after acute cardiac syndrome produces a significant physical frailty improvement in those patients with worse frailty phenotype with an impairment in chair standing or balance at entry.
MeSH term(s)	Humans ; Frailty/diagnosis ; Cardiac Rehabilitation ; Recovery of Function ; Hospitalization ; Physical Functional Performance
Language	English
Publishing date	2023-03-30
Publishing country	Japan
Document type	Journal Article
ZDB-ID	89678-0
ISSN	1615-2573 ; 0910-8327 ; 0935-736X
ISSN (online)	1615-2573
ISSN	0910-8327 ; 0935-736X
DOI	10.1007/s00380-023-02254-9
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