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  1. Article ; Online: Combined functional and anatomical assessment of coronary stenosis by coronary CT angiography.

    Andreini, Daniele

    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology

    2021  Volume 17, Issue 7, Page(s) 534–535

    MeSH term(s) Computed Tomography Angiography ; Coronary Angiography ; Coronary Stenosis/diagnostic imaging ; Fractional Flow Reserve, Myocardial ; Humans ; Tomography, X-Ray Computed
    Language English
    Publishing date 2021-09-25
    Publishing country France
    Document type Journal Article
    ZDB-ID 2457174-X
    ISSN 1969-6213 ; 1774-024X
    ISSN (online) 1969-6213
    ISSN 1774-024X
    DOI 10.4244/EIJV17I7A96
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  2. Article ; Online: Role of coronary computed tomography angiography to optimise percutaneous coronary intervention outcomes.

    Bouisset, Frederic / Ohashi, Hirofumi / Andreini, Daniele / Collet, Carlos

    Heart (British Cardiac Society)

    2023  

    Language English
    Publishing date 2023-09-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 1303417-0
    ISSN 1468-201X ; 1355-6037
    ISSN (online) 1468-201X
    ISSN 1355-6037
    DOI 10.1136/heartjnl-2023-322889
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  3. Article ; Online: Artificial intelligence-powered insights into high-risk, non-obstructive coronary atherosclerosis: a case report.

    Provera, Andrea / Andreini, Daniele / Petersen, Kersten / Gallinoro, Emanuele / Conte, Edoardo

    European heart journal. Case reports

    2024  Volume 8, Issue 4, Page(s) ytae172

    Abstract: Background: Advanced coronary plaque analysis by cardiac computed tomography (CT) has recently emerged as a promising technique for better prognostic stratification. However, this evaluation application in clinical practice is still uncertain.: Case ... ...

    Abstract Background: Advanced coronary plaque analysis by cardiac computed tomography (CT) has recently emerged as a promising technique for better prognostic stratification. However, this evaluation application in clinical practice is still uncertain.
    Case summary: In the present case, we described the clinical picture of a 44-year-old tennis player with ectopic ventricular beats in which cardiac CT enabled the identification of a non-obstructive but high-risk plaque on proximal left anterior descendent artery. The application of artificial intelligence (AI)-enhanced software enabled to better stratify the patients' risk. The present case describes how early identification of non-obstructive but high-risk coronary plaque evaluated by cardiac CT using AI-enhanced software enabled accurate and personalized risk assessment.
    Discussion: The main clinical message of this case report is that advanced plaque analysis by cardiac CT, especially when performed with AI-based software, may provide important prognostic information leading to a personalized preventive approach. Moreover, AI-based software may contribute to promote a routine evaluation of these important data already included in traditional cardiac CT.
    Language English
    Publishing date 2024-04-09
    Publishing country England
    Document type Case Reports
    ISSN 2514-2119
    ISSN (online) 2514-2119
    DOI 10.1093/ehjcr/ytae172
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  4. Article: In search of new gatekeepers: coronary CT (Computed Tomography) in acute coronary syndrome.

    Schillaci, Matteo / Marchetti, Davide / Andreini, Daniele

    European heart journal supplements : journal of the European Society of Cardiology

    2023  Volume 25, Issue Suppl B, Page(s) B1–B6

    Abstract: Coronary computed tomography (CCT) is a non-invasive imaging method that allows visualization of the epicardial coronary arteries. The diagnostic and prognostic role of CCT has been demonstrated by various randomized trials to such an extent that it has ... ...

    Abstract Coronary computed tomography (CCT) is a non-invasive imaging method that allows visualization of the epicardial coronary arteries. The diagnostic and prognostic role of CCT has been demonstrated by various randomized trials to such an extent that it has been included as a Class I, level of evidence B recommendation in the latest European Society of Cardiology (ESC) guidelines for the diagnosis of chronic coronary syndrome in patients at intermediate-low cardiovascular risk. In addition to the anatomical evaluation, the CCT allows to evaluate the presence of high-risk characteristics of the atherosclerotic plaque (napkin-ring sign, positive remodelling, spotty calcification, and low-attenuation plaque), thus discriminating the stability of the atheromatous pathology. Furthermore, among the potential of cardiac CT in the emergency department, the possibility of making a triple rule-out must be underlined, excluding three potential big killers as the cause of acute chest pain: acute coronary syndrome, pulmonary embolism, and aortic dissection. Various randomized clinical studies have demonstrated that the prognosis of the patient with chronic coronary artery disease (CAD) improves only if a haemodynamically significant stenosis is treated, generally investigated with invasive fractional flow reserve (FFR); CCT technological advances have made it possible to create an algorithm for calculating the FFR-CT, an index of haemodynamic significance of coronary stenosis, whose correlation with the invasive FFR data and, consequently, with the prognosis has been demonstrated of patients with CAD.
    Language English
    Publishing date 2023-04-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 1463769-8
    ISSN 1554-2815 ; 1520-765X
    ISSN (online) 1554-2815
    ISSN 1520-765X
    DOI 10.1093/eurheartjsupp/suad076
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  5. Article ; Online: Screening CT Angiography in Asymptomatic Diabetes Mellitus?

    Andreini, Daniele

    JACC. Cardiovascular imaging

    2016  Volume 9, Issue 11, Page(s) 1301–1303

    Language English
    Publishing date 2016-11
    Publishing country United States
    Document type Editorial
    ZDB-ID 2491503-8
    ISSN 1876-7591 ; 1936-878X
    ISSN (online) 1876-7591
    ISSN 1936-878X
    DOI 10.1016/j.jcmg.2016.01.039
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  6. Article ; Online: Coronary CT as a first-line investigation in chronic coronary syndromes: pros and cons.

    Bartorelli, Antonio L / Andreini, Daniele / Giustino, Gennaro / Dangas, George

    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology

    2023  Volume 19, Issue 6, Page(s) 459–461

    MeSH term(s) Humans ; Syndrome ; Thoracic Surgical Procedures ; Tomography, X-Ray Computed
    Language English
    Publishing date 2023-08-22
    Publishing country France
    Document type Journal Article
    ZDB-ID 2457174-X
    ISSN 1969-6213 ; 1774-024X
    ISSN (online) 1969-6213
    ISSN 1774-024X
    DOI 10.4244/EIJ-E-23-00013
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  7. Article ; Online: Dual Energy Coronary Computed Tomography Angiography for Detection and Quantification of Atherosclerotic Burden: Diagnostic and Prognostic Significance.

    Andreini, Daniele

    Revista espanola de cardiologia (English ed.)

    2016  Volume 69, Issue 10, Page(s) 885–887

    MeSH term(s) Computed Tomography Angiography ; Coronary Angiography ; Coronary Artery Disease ; Coronary Stenosis ; Humans ; Plaque, Atherosclerotic ; Prognosis ; Tomography, X-Ray Computed
    Language Spanish
    Publishing date 2016
    Publishing country Spain
    Document type Editorial ; Comment
    ISSN 1885-5857
    ISSN (online) 1885-5857
    DOI 10.1016/j.rec.2016.04.048
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  8. Article ; Online: Reply to: The spectrum of pericardial syndromes in patients with pectus excavatum.

    Conte, Edoardo / Carollo, Chiara / Andreini, Daniele / Brucato, Antonio

    International journal of cardiology

    2021  Volume 346, Page(s) 79

    MeSH term(s) Funnel Chest/diagnostic imaging ; Funnel Chest/epidemiology ; Humans ; Pericardial Effusion/diagnostic imaging ; Pericardial Effusion/epidemiology ; Pericardium/diagnostic imaging ; Syndrome
    Language English
    Publishing date 2021-11-16
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2021.11.034
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    Zs.A 1673: Show issues Location:
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  9. Article ; Online: Clinical and cardiac CT characteristics of congenital coronary abnormalities occasionally detected in a middle-aged population: A long-term follow-up study.

    Conte, Edoardo / Marchetti, Davide / Melotti, Eleonora / Schillaci, Matteo / Mushtaq, Saima / Maffi, Vanessa / Pontone, Gianluca / Bartorelli, Antonio / Andreini, Daniele

    Journal of cardiovascular computed tomography

    2024  

    Abstract: Introduction: Congenital coronary artery anomalies (CCAA) represent one of the most challenging conditions as their clinical presentation may range from sudden cardiac death to a complete subclinical form. The aim of the present study was to evaluate ... ...

    Abstract Introduction: Congenital coronary artery anomalies (CCAA) represent one of the most challenging conditions as their clinical presentation may range from sudden cardiac death to a complete subclinical form. The aim of the present study was to evaluate the diagnostic and prognostic role of cardiac CT (CCT) evaluation in patients with CCAA, focusing on anomalies of origin.
    Material and methods: The present is a retrospective analysis of a prospective clinical registry including a consecutive cohort of patients who underwent clinically indicated CCT from January 2007 to October 2015 for suspected but unknown coronary artery disease (CAD) and were diagnosed for having a congenital coronary abnormality compared to a control group matched for age, sex and segment stenosis score (SSS). Dedicated analysis of all CCT was performed for the present study and only coronary anomalies of origin were considered and included in the study. Two different composite end-points were identified for the present analysis: major cardiovascular events (MACE) and all-cause of death.
    Results: Among the 81 patients with CCAAs enrolled the most frequent anomaly was left main artery absence, which was identified in 41 individuals (50.6%). Forty-five subjects (55.5%) have an anomalous origin of the coronary artery from a different sinus of Valsalva and 45 subjects had also an anomalous course with the retro-aortic being the most common (32%). Eleven participants (13.6%) displayed also an intramural segment, while 10 (10.3%) had a slit-like ostial morphology. At multivariate analysis CT identification of ARCA, anomalous inter-arterial course and abnormal ostial morphology were significantly associated with MACE even when adjusted for age and SSS, without any differences in all-cause mortality between the two groups (6.2% vs 2.4% p ​= ​0.2478).
    Conclusion: The result of the present study is that CCT can be successfully used to define the anatomy and features of CAA. It suggested that in middle-aged patients, the identification of high risk characteristics at CT may have a prognostic value in term of cardiovascular events occurrence at follow-up even if the rate of events strictly linked to CCAA is low.
    Language English
    Publishing date 2024-04-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2394360-9
    ISSN 1876-861X ; 1934-5925
    ISSN (online) 1876-861X
    ISSN 1934-5925
    DOI 10.1016/j.jcct.2024.04.002
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  10. Article ; Online: Coronary plaque features on CTA can identify patients at increased risk of cardiovascular events.

    Andreini, Daniele / Conte, Edoardo / Serruys, Patrick W

    Current opinion in cardiology

    2021  Volume 36, Issue 6, Page(s) 784–792

    Abstract: Purpose of review: Multicenter studies showed that the characterization of coronary atherosclerosis by coronary computed tomography (CT) angiography (CCTA) provides independent and incremental prognostic value above and beyond traditional measures of ... ...

    Abstract Purpose of review: Multicenter studies showed that the characterization of coronary atherosclerosis by coronary computed tomography (CT) angiography (CCTA) provides independent and incremental prognostic value above and beyond traditional measures of coronary artery disease (CAD) and is able to identify patients at risk of future event. Aim of the present review is to expound the major imaging plaque features associated with increased risk of coronary event and to review the data supporting the usefulness of CCTA as tool for plaque assessment and for monitoring the changes in atherosclerotic burden.
    Recent findings: The evaluation of coronary atherosclerosis, including the measurement of imaging risk scores (e.g. CT-adapted Leaman score) was demonstrated as independent long-term predictor of acute coronary events. In particular, qualitative (remodelling index, low-attenuation plaque, napkin-ring sign, small spotty calcifications) and quantitative (plaque burden, total-, noncalcific- and fibrofatty plaque volume) plaque features were associated with increased risk. CCTA was also demonstrated to accurately quantify plaque volume vs. intravascular ultrasound and findings from PARADIGM and EVAPORATE studies supported the use of CCTA as noninvasive tool to follow the effect of medication on plaque progression/regression. Finally, interesting relationship between plaque features, coronary physiology and biomarkers have been described.
    Summary: Latest guidelines on the management of patients with stable CAD recommended CCTA in Class I of evidence, particularly when 'information on atherosclerosis are desired', underlining the usefulness of CCTA to characterize and quantify the atherosclerotic burden.
    MeSH term(s) Computed Tomography Angiography ; Coronary Angiography ; Coronary Artery Disease/diagnostic imaging ; Humans ; Plaque, Atherosclerotic/diagnostic imaging ; Tomography, X-Ray Computed
    Language English
    Publishing date 2021-10-07
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 645186-x
    ISSN 1531-7080 ; 0268-4705
    ISSN (online) 1531-7080
    ISSN 0268-4705
    DOI 10.1097/HCO.0000000000000917
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