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Article ; Online: Impact of time to revascularization on outcomes in patients after out-of-hospital cardiac arrest with STEMI.

Nakajima, Satoshi / Matsuyama, Tasuku / Kandori, Kenji / Okada, Asami / Okada, Yohei / Kitamura, Tetsuhisa / Ohta, Bon

The American journal of emergency medicine

2024 Volume 79, Page(s) 136–143

Abstract: Background: International guidelines recommend emergency coronary angiography in patients after out-of-hospital cardiac arrest (OHCA) with ST-segment elevation on 12‑lead electrocardiography. However, the association between time to revascularization ... ...

Abstract	Background: International guidelines recommend emergency coronary angiography in patients after out-of-hospital cardiac arrest (OHCA) with ST-segment elevation on 12‑lead electrocardiography. However, the association between time to revascularization and outcomes remains unknown. This study aimed to evaluate the association between time to revascularization and outcomes in patients with OHCA due to ST-segment-elevation myocardial infarction (STEMI) who underwent percutaneous coronary intervention (PCI). Methods: This multicenter, retrospective, nationwide observational study included patients aged ≥18 years with OHCA due to STEMI who underwent PCI between 2014 and 2020. The time of the first return of spontaneous circulation (ROSC) was defined as the time of first ROSC during resuscitation, regardless of the pre-hospital or in-hospital setting. The primary outcome was a 1-month favorable neurological outcome, defined as cerebral performance category 1 or 2. Multivariable logistic regression analysis was used to assess the association between the time to revascularization and favorable neurological outcomes. Results: A total of 547 patients were included in this analysis. The multivariable logistic regression analysis showed that a shorter time from the first ROSC to revascularization was associated with 1-month favorable neurological outcomes (63/86 [73.3%] in the time from the first ROSC to revascularization ≤60 min group versus 98/193 [50.8%] in the >120 min group; adjusted OR, 0.26; 95% CI, 0.11-0.56; P for trend, 0.015). Conclusions: Shorter time to revascularization was significantly associated with 1-month favorable neurological outcomes in patients with OHCA due to STEMI who underwent PCI.
MeSH term(s)	Humans ; Adolescent ; Adult ; ST Elevation Myocardial Infarction/surgery ; Out-of-Hospital Cardiac Arrest/therapy ; Percutaneous Coronary Intervention ; Retrospective Studies ; Resuscitation ; Coronary Angiography ; Treatment Outcome ; Cardiopulmonary Resuscitation
Language	English
Publishing date	2024-02-23
Publishing country	United States
Document type	Observational Study ; Multicenter Study ; Journal Article
ZDB-ID	605890-5
ISSN	1532-8171 ; 0735-6757
ISSN (online)	1532-8171
ISSN	0735-6757
DOI	10.1016/j.ajem.2024.02.030
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Increased CT Use and No Change in Injury Severity among Child Motor Vehicle Victims: A National Trauma Database Study in Japan.

Ishii, Wataru / Hitosugi, Masahito / Kandori, Kenji / Miyaguni, Michitaro / Iizuka, Ryoji

Healthcare (Basel, Switzerland)

2023 Volume 11, Issue 9

Abstract: The number of fatalities associated with traffic accidents has been declining owing to improvements in vehicle safety performance and changes in the law. However, injuries in children can lead to social and economic losses. We examined 10-year changes in ...

Abstract	The number of fatalities associated with traffic accidents has been declining owing to improvements in vehicle safety performance and changes in the law. However, injuries in children can lead to social and economic losses. We examined 10-year changes in the characteristics of traffic trauma among pediatric motor vehicle passengers by analyzing data from the Japan Trauma Data Bank (JTDB). Among the 36,715 injured motor vehicle passengers under the age of 15 years who were registered in the JTDB from 2004 to 2019, we compared the groups injured during 2004-2007 (
Language	English
Publishing date	2023-04-26
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2721009-1
ISSN	2227-9032
ISSN	2227-9032
DOI	10.3390/healthcare11091240
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Article ; Online: Association between eGFR and neurological outcomes among patients with out-of-hospital cardiac arrest: A nationwide prospective study in Japan.

Kandori, Kenji / Okada, Asami / Nakajima, Satoshi / Matsuyama, Tasuku / Kitamura, Tetsuhisa / Narumiya, Hiromichi / Iizuka, Ryoji / Hitosugi, Masahito / Okada, Yohei

Acute medicine & surgery

2024 Volume 11, Issue 1, Page(s) e952

Abstract: Aim: We aimed to investigate the association between estimated glomerular filtration rate and prognosis in out-of-hospital cardiac arrest patients and explore the heterogeneity of the association.: Methods: Patients experiencing out-of-hospital ... ...

Abstract	Aim: We aimed to investigate the association between estimated glomerular filtration rate and prognosis in out-of-hospital cardiac arrest patients and explore the heterogeneity of the association. Methods: Patients experiencing out-of-hospital cardiac arrest due to medical causes and registered in the JAAM-OHCA Registry between June 2014 and December 2019 were stratified into shockable rhythm, pulseless electrical activity, and asystole groups according to the cardiac rhythm at the scene. The primary outcome was a 1-month favorable neurological status. Adjusted odds ratios with 95% confidence intervals were calculated to investigate the association between estimated glomerular filtration rate and outcomes using a logistic model. Results: Of the 19,443 patients included, 2769 had initial shockable rhythm at the scene, 5339 had pulseless electrical activity, and 11,335 had asystole. As the estimated glomerular filtration rate decreased, the adjusted odds ratio for a 1-month favorable neurological status decreased among those with initial shockable rhythm (estimated glomerular filtration rate, adjusted odds ratio [95% CI]: 45-59 mL/min/1.73 m Conclusion: The estimated glomerular filtration rate is associated with neurological prognosis in out-of-hospital cardiac arrest patients with initial shockable rhythm at the scene but not in those with initial non-shockable rhythm.
Language	English
Publishing date	2024-04-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	2751184-4
ISSN	2052-8817 ; 2052-8817
ISSN (online)	2052-8817
ISSN	2052-8817
DOI	10.1002/ams2.952
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Article ; Online: Physiological status and anatomical severity factors associated with child versus adult bicyclist fatalities based on a national trauma dataset.

Ishii, Wataru / Hitosugi, Masahito / Kandori, Kenji / Miyaguni, Michitaro / Iizuka, Ryoji

Scientific reports

2022 Volume 12, Issue 1, Page(s) 18354

Abstract: Bicyclists still account for the majority of child deaths in traffic accidents, despite a gradual decrease in incidence. Therefore, we investigated factors associated with child and adult bicyclist fatalities. In this retrospective study, we used data ... ...

Abstract	Bicyclists still account for the majority of child deaths in traffic accidents, despite a gradual decrease in incidence. Therefore, we investigated factors associated with child and adult bicyclist fatalities. In this retrospective study, we used data from a national hospital-based database, the Japan Trauma Data Bank. Data from 2004 to 2019 were obtained for child cyclists (5-18 years; n = 4832) and adult cyclists (26-45 years; n = 3449). In each age group, physiological variables, outcomes, and injury severity were compared between fatal and non-fatal cases. Multivariate logistic regression was performed to determine factors associated with fatality. In adults, fatality was associated with lower values for body temperature, Glasgow Coma Scale score, and Abbreviated Injury Scale (AIS) score for the neck and upper extremities, and with higher values for respiratory rate, heart rate, focused assessment with sonography for trauma positivity rate, and AIS scores for the head, chest, and abdomen. In children, fatality was associated with lower values for body temperature and the Glasgow Coma Scale score, and with higher values for the AIS chest score. These findings point to factors associated with bicyclist fatalities and may help in the development of effective strategies to reduce these fatalities.
MeSH term(s)	Adult ; Child ; Humans ; Bicycling ; Retrospective Studies ; Accidents, Traffic ; Abbreviated Injury Scale ; Glasgow Coma Scale
Language	English
Publishing date	2022-11-01
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-022-21949-z
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Article ; Online: Reply to: Coronavirus disease 2019 and ethical considerations for extracorporeal cardiopulmonary resuscitation.

Kandori, Kenji / Narumiya, Hiromichi / Iizuka, Ryoji

Resuscitation

2020 Volume 154, Page(s) 129–130

MeSH term(s)	Betacoronavirus ; COVID-19 ; Cardiopulmonary Resuscitation ; Coronavirus ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
Keywords	covid19
Language	English
Publishing date	2020-07-22
Publishing country	Ireland
Document type	Letter ; Comment
ZDB-ID	189901-6
ISSN	1873-1570 ; 0300-9572
ISSN (online)	1873-1570
ISSN	0300-9572
DOI	10.1016/j.resuscitation.2020.07.012
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Article ; Online: Extracorporeal cardiopulmonary resuscitation should not be performed on confirmed or suspected COVID-19 patients.

Kandori, Kenji / Narumiya, Hiromichi / Iizuka, Ryoji

Resuscitation

2020 Volume 153, Page(s) 6–7

MeSH term(s)	Betacoronavirus ; COVID-19 ; Cardiopulmonary Resuscitation/adverse effects ; Coronavirus Infections/complications ; Coronavirus Infections/transmission ; Decision Making ; Extracorporeal Membrane Oxygenation/adverse effects ; Humans ; Infectious Disease Transmission, Patient-to-Professional/prevention & control ; Male ; Occupational Exposure/adverse effects ; Out-of-Hospital Cardiac Arrest/therapy ; Pandemics ; Personal Protective Equipment ; Pneumonia, Viral/complications ; Pneumonia, Viral/transmission ; SARS-CoV-2 ; Young Adult
Keywords	covid19
Language	English
Publishing date	2020-05-31
Publishing country	Ireland
Document type	Case Reports ; Letter
ZDB-ID	189901-6
ISSN	1873-1570 ; 0300-9572
ISSN (online)	1873-1570
ISSN	0300-9572
DOI	10.1016/j.resuscitation.2020.05.040
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Article: Factors Affecting Death and Severe Injury in Child Motor Vehicle Passengers.

Ishii, Wataru / Hitosugi, Masahito / Baba, Mineko / Kandori, Kenji / Arai, Yusuke

Healthcare (Basel, Switzerland)

2021 Volume 9, Issue 11

Abstract: Saving children from motor vehicle collisions is a high priority because the injury rate among motor vehicle passengers has been increasing in Japan. This study aimed to examine the factors that influence death and serious injury in child motor vehicle ... ...

Abstract	Saving children from motor vehicle collisions is a high priority because the injury rate among motor vehicle passengers has been increasing in Japan. This study aimed to examine the factors that influence death and serious injury in child motor vehicle passengers to establish effective preventive measures. To identify these factors, we performed a retrospective study using a nationwide medical database. The data of child motor vehicle passengers younger than 15 years (
Language	English
Publishing date	2021-10-24
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2721009-1
ISSN	2227-9032
ISSN	2227-9032
DOI	10.3390/healthcare9111431
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Article ; Online: Physiological status and anatomical severity factors associated with child versus adult bicyclist fatalities based on a national trauma dataset

Wataru Ishii / Masahito Hitosugi / Kenji Kandori / Michitaro Miyaguni / Ryoji Iizuka

Scientific Reports, Vol 12, Iss 1, Pp 1-

2022 Volume 8

Abstract: Abstract Bicyclists still account for the majority of child deaths in traffic accidents, despite a gradual decrease in incidence. Therefore, we investigated factors associated with child and adult bicyclist fatalities. In this retrospective study, we ... ...

Abstract	Abstract Bicyclists still account for the majority of child deaths in traffic accidents, despite a gradual decrease in incidence. Therefore, we investigated factors associated with child and adult bicyclist fatalities. In this retrospective study, we used data from a national hospital-based database, the Japan Trauma Data Bank. Data from 2004 to 2019 were obtained for child cyclists (5–18 years; n = 4832) and adult cyclists (26–45 years; n = 3449). In each age group, physiological variables, outcomes, and injury severity were compared between fatal and non-fatal cases. Multivariate logistic regression was performed to determine factors associated with fatality. In adults, fatality was associated with lower values for body temperature, Glasgow Coma Scale score, and Abbreviated Injury Scale (AIS) score for the neck and upper extremities, and with higher values for respiratory rate, heart rate, focused assessment with sonography for trauma positivity rate, and AIS scores for the head, chest, and abdomen. In children, fatality was associated with lower values for body temperature and the Glasgow Coma Scale score, and with higher values for the AIS chest score. These findings point to factors associated with bicyclist fatalities and may help in the development of effective strategies to reduce these fatalities.
Keywords	Medicine ; R ; Science ; Q
Subject code	360
Language	English
Publishing date	2022-11-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Adverse events of emergency surgical front of neck airway access: an observational descriptive study.

Okada, Asami / Okada, Yohei / Kandori, Kenji / Ishii, Wataru / Narumiya, Hiromichi / Iizuka, Ryoji

Acute medicine & surgery

2022 Volume 9, Issue 1, Page(s) e750

Abstract: Aim: Emergency front of neck access (eFONA), such as scalpel cricothyroidotomy, is a rescue technique used to open the airway during "cannot intubate, cannot oxygenate" situations. However, little is known about the adverse events associated with the ... ...

Abstract	Aim: Emergency front of neck access (eFONA), such as scalpel cricothyroidotomy, is a rescue technique used to open the airway during "cannot intubate, cannot oxygenate" situations. However, little is known about the adverse events associated with the procedure. This study aimed to describe the adverse events that occur in patients who undergo eFONA and their management. Methods: This retrospective observational cohort study included emergency patients who underwent eFONA between April 2012 and August 2020. We described the patients' characteristics and the adverse events during or immediately after the procedure. Results: Among 75,529 emergency patients during the study period, 31 (0.04%) underwent an eFONA. The median (interquartile range) age was 53 (39-67) years, and 23 patients (74.2%) were men. Of all cases, 13 (41.9%) experienced adverse events. Of these, three cases (23.2%) were cephalad misplacement of the intubation tube, one case (7.7%) was cuff injury, one case (7.7%) was tube obstruction due to vomiting, and one case (7.7%) was tube kink. In cases with these adverse events, the initial attempt of eFONA failed, and alternative immediate action was necessary to secure the airway. Conclusion: This single-center retrospective observational study described several adverse events of eFONA. In particular, it is important to understand the possible life-threatening adverse events that lead to failure of securing airways such as cephalad displacement, tube obstruction, and tube kink and respond promptly to ensure a secure definitive airway for patients' safety.
Language	English
Publishing date	2022-04-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2751184-4
ISSN	2052-8817 ; 2052-8817
ISSN (online)	2052-8817
ISSN	2052-8817
DOI	10.1002/ams2.750
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Article ; Online: Evaluation of a revised resuscitation protocol for out-of-hospital cardiac arrest patients due to COVID-19 safety protocols: a single-center retrospective study in Japan.

Kandori, Kenji / Okada, Yohei / Ishii, Wataru / Narumiya, Hiromichi / Iizuka, Ryoji

Scientific reports

2021 Volume 11, Issue 1, Page(s) 12985

Abstract: This study aimed to determine the association between cardiopulmonary resuscitation (CPR) under the coronavirus 2019 (COVID-19) safety protocols in our hospital and the prognosis of out-of-hospital cardiac arrest (OHCA) patients, in an urban area, where ... ...

Abstract	This study aimed to determine the association between cardiopulmonary resuscitation (CPR) under the coronavirus 2019 (COVID-19) safety protocols in our hospital and the prognosis of out-of-hospital cardiac arrest (OHCA) patients, in an urban area, where the prevalence of COVID-19 infection is relatively low. This was a single-center, retrospective, observational, cohort study conducted at a tertiary critical care center in Kyoto City, Japan. Adult OHCA patients arriving at our hospital under CPR between January 1, 2019, and December 31, 2020 were included. Our hospital implemented a revised resuscitation protocol for OHCA patients on April 1, 2020 to prevent COVID-19 transmission. This study defined the conventional CPR period as January 1, 2019 to March 31, 2020, and the COVID-19 safety protocol period as April 1, 2020 to December 31, 2020. Throughout the prehospital and in-hospital settings, resuscitation protocols about wearing personal protective equipment and airway management were revised in order to minimize the risk of infection; otherwise, the other resuscitation management had not been changed. The primary outcome was hospitalization survival. The secondary outcomes were return of spontaneous circulation after hospital arrival and 1-month survival after OHCA occurrence. The adjusted odds ratios with 95% confidence intervals (CI) were calculated for outcomes to compare the two study periods, and the multivariable logistic model was used to adjust for potential confounders. The study analyzed 443 patients, with a median age of 76 years (65-85), and included 261 men (58.9%). The percentage of hospitalization survivors during the entire research period was 16.9% (75/443 patients), with 18.7% (50/267) during the conventional CPR period and 14.2% (25/176) during the COVID-19 safety protocol period. The adjusted odds ratio for hospitalization survival during the COVID-19 safety protocol period was 0.61 (95% CI 0.32-1.18), as compared with conventional CPR. There were no cases of COVID-19 infection among the staff involved in the resuscitation in our hospital. There was no apparent difference in hospitalization survival between the OHCA patients resuscitated under the conventional CPR protocol compared with the current revised protocol for controlling COVID-19 transmission.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19/virology ; Cardiopulmonary Resuscitation/methods ; Emergency Medical Services/methods ; Female ; Hospitalization ; Humans ; Japan/epidemiology ; Male ; Middle Aged ; Odds Ratio ; Out-of-Hospital Cardiac Arrest/therapy ; Retrospective Studies ; SARS-CoV-2 ; Treatment Outcome ; Young Adult
Language	English
Publishing date	2021-06-21
Publishing country	England
Document type	Journal Article ; Observational Study
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-021-92415-5
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