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Article: The effect of a single-session heart rate variability biofeedback on attentional control: does stress matter?

Blaser, Berenike L / Weymar, Mathias / Wendt, Julia

2023 Volume 14, Page(s) 1292983

Abstract: Introduction: Vagally mediated heart rate variability is an index of autonomic nervous system activity that is associated with a large variety of outcome variables including psychopathology and self-regulation. While practicing heart rate variability ... ...

Abstract	Introduction: Vagally mediated heart rate variability is an index of autonomic nervous system activity that is associated with a large variety of outcome variables including psychopathology and self-regulation. While practicing heart rate variability biofeedback over several weeks has been reliably associated with a number of positive outcomes, its acute effects are not well known. As the strongest association with vagally mediated heart rate variability has been found particularly within the attention-related subdomain of self-regulation, we investigated the acute effect of heart rate variability biofeedback on attentional control using the revised Attention Network Test. Methods: Fifty-six participants were tested in two sessions. In one session each participant received a heart rate variability biofeedback intervention, and in the other session a control intervention of paced breathing at a normal ventilation rate. After the biofeedback or control intervention, participants completed the Attention Network Test using the Orienting Score as a measure of attentional control. Results: Mixed models revealed that higher resting baseline vagally mediated heart rate variability was associated with better performance in attentional control, which suggests more efficient direction of attention to target stimuli. There was no significant main effect of the intervention on attentional control. However, an interaction effect indicated better performance in attentional control after biofeedback in individuals who reported higher current stress levels. Discussion: The results point to acute beneficial effects of heart rate variability biofeedback on cognitive performance in highly stressed individuals. Although promising, the results need to be replicated in larger or more targeted samples in order to reach stronger conclusions about the effects.
Language	English
Publishing date	2023-11-16
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2563826-9
ISSN	1664-1078
ISSN	1664-1078
DOI	10.3389/fpsyg.2023.1292983
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Article ; Online: Ökonomische Erhebung prämenstrueller Symptomatik – Deutsche Übersetzung der Kurzversion der Premenstrual Assessment Form und deren psychometrische Überprüfung.

Blaser, Berenike Lisa / Weymar, Mathias / Wendt, Julia

Psychotherapie, Psychosomatik, medizinische Psychologie

2023 Volume 73, Issue 9-10, Page(s) 405–412

Abstract: Premenstrual symptomatology is a widespread and yet under-researched problem. To date, there is no German instrument for assessing the broad spectrum of possible symptoms and their degree of expression. For this reason, the short versions of the ... ...

Title translation	Efficient assessment of premenstrual symptoms - German translation of the shortened Premenstrual Assessment Form and its psychometric evaluation.
Abstract	Premenstrual symptomatology is a widespread and yet under-researched problem. To date, there is no German instrument for assessing the broad spectrum of possible symptoms and their degree of expression. For this reason, the short versions of the Premenstrual Assessment Form with 20 and 10 items were translated and validated in a sample of N=147 menstruating persons. The internal consistencies of the 20-item and 10-item versions are high (Cronbach's α
MeSH term(s)	Humans ; Psychometrics ; Surveys and Questionnaires ; Reproducibility of Results ; Factor Analysis, Statistical ; Diagnostic and Statistical Manual of Mental Disorders
Language	German
Publishing date	2023-08-24
Publishing country	Germany
Document type	English Abstract ; Journal Article
ZDB-ID	800571-0
ISSN	1439-1058 ; 0173-7937 ; 0937-2032
ISSN (online)	1439-1058
ISSN	0173-7937 ; 0937-2032
DOI	10.1055/a-2136-6941
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Article ; Online: A new lexicon in the age of microbiome research.

Bosch, Thomas C G / Blaser, Martin J / Ruby, Edward / McFall-Ngai, Margaret

Philosophical transactions of the Royal Society of London. Series B, Biological sciences

2024 Volume 379, Issue 1901, Page(s) 20230060

Abstract: At a rapid pace, biologists are learning the many ways in which resident microbes influence, and sometimes even control, their hosts to shape both health and disease. Understanding the biochemistry behind these interactions promises to reveal completely ... ...

Abstract	At a rapid pace, biologists are learning the many ways in which resident microbes influence, and sometimes even control, their hosts to shape both health and disease. Understanding the biochemistry behind these interactions promises to reveal completely novel and targeted ways of counteracting disease processes. However, in our protocols and publications, we continue to describe these new results using a language that originated in a completely different context. This language developed when microbial interactions with hosts were perceived to be primarily pathogenic, as threats that had to be vanquished. Biomedicine had one dominating thought: winning this war against microorganisms. Today, we know that beyond their defensive roles, host tissues, especially epithelia, are vital to ensuring association with the normal microbiota, the communities of microbes that persistently live with the host. Thus, we need to adopt a language that better encompasses the newly appreciated importance of host-microbiota associations. We also need a language that frames the onset and progression of pathogenic conditions within the context of the normal microbiota. Such a reimagined lexicon should make it clear, from the very nature of its words, that microorganisms are primarily vital to our health, and only more rarely the cause of disease. This article is part of the theme issue 'Sculpting the microbiome: how host factors determine and respond to microbial colonization'.
MeSH term(s)	Humans ; Symbiosis ; Microbiota ; Communicable Diseases ; Microbial Interactions ; Learning
Language	English
Publishing date	2024-03-18
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	208382-6
ISSN	1471-2970 ; 0080-4622 ; 0264-3839 ; 0962-8436
ISSN (online)	1471-2970
ISSN	0080-4622 ; 0264-3839 ; 0962-8436
DOI	10.1098/rstb.2023.0060
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Article ; Online: Detection of Scedosporium spp.: Colonizer or pathogen? A retrospective analysis of clinical significance and management in a large tertiary center.

Reinhold, Ilana / Quiblier, Chantal / Blaser, Frank / Bögeholz, Jan / Imkamp, Frank / Schuurmans, Macé M / Soyka, Michael B / Zbinden, Reinhard / Mueller, Nicolas J

Medical mycology

2024 Volume 62, Issue 2

Abstract: Infections with Scedosporium spp. are emerging in the past two decades and are associated with a high mortality rate. Microbiological detection can be associated with either colonization or infection. Evolution from colonization into infection is ... ...

Abstract	Infections with Scedosporium spp. are emerging in the past two decades and are associated with a high mortality rate. Microbiological detection can be associated with either colonization or infection. Evolution from colonization into infection is difficult to predict and clinical management upon microbiological detection is complex. Microbiological samples from 2015 to 2021 were retrospectively analyzed in a single tertiary care center. Classification into colonization or infection was performed upon first microbiological detection. Clinical evolution was observed until July 2023. Further diagnostic procedures after initial detection were analyzed. Among 38 patients with microbiological detection of Scedosporium spp., 10 were diagnosed with an infection at the initial detection and two progressed from colonization to infection during the observation time. The main sites of infection were lung (5/12; 41.6%) followed by ocular sites (4/12; 33.3%). Imaging, bronchoscopy or biopsies upon detection were performed in a minority of patients. Overall mortality rate was similar in both groups initially classified as colonization or infection [30.7% and 33.3%, respectively (P = 1.0)]. In all patients where surgical debridement of site of infection was performed (5/12; 42%); no death was observed. Although death occurred more often in the group without eradication (3/4; 75%) compared with the group with successful eradication (1/8; 12.5%), statistical significance could not be reached (P = 0.053). As therapeutic management directly impacts patients' outcome, a multidisciplinary approach upon microbiological detection of Scedosporium spp. should be encouraged. Data from larger cohorts are warranted in order to analyze contributing factors favoring the evolution from colonization into infection.
MeSH term(s)	Humans ; Retrospective Studies ; Scedosporium ; Antifungal Agents/therapeutic use ; Clinical Relevance ; Risk Factors
Chemical Substances	Antifungal Agents
Language	English
Publishing date	2024-01-19
Publishing country	England
Document type	Journal Article
ZDB-ID	1421796-x
ISSN	1460-2709 ; 1369-3786
ISSN (online)	1460-2709
ISSN	1369-3786
DOI	10.1093/mmy/myae002
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Article ; Online: Disturbing the neonatal microbiome is a small price to pay for preventing early-onset neonatal group B streptococcus disease: AGAINST: Against relying on antibiotics to prevent early-onset neonatal group B streptococcus disease.

Aronoff, David M / Blaser, Martin J

BJOG : an international journal of obstetrics and gynaecology

2019 Volume 127, Issue 2, Page(s) 229

MeSH term(s)	Adult ; Anti-Bacterial Agents/therapeutic use ; Antibiotic Prophylaxis ; Drug Resistance, Microbial/drug effects ; Female ; Humans ; Infant, Newborn ; Infectious Disease Transmission, Vertical/prevention & control ; Pregnancy ; Pregnancy Complications, Infectious/drug therapy ; Risk Factors ; Streptococcal Infections/drug therapy ; Streptococcal Infections/prevention & control ; Streptococcus agalactiae/drug effects
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2019-11-06
Publishing country	England
Document type	Journal Article
ZDB-ID	2000931-8
ISSN	1471-0528 ; 0306-5456 ; 1470-0328
ISSN (online)	1471-0528
ISSN	0306-5456 ; 1470-0328
DOI	10.1111/1471-0528.15988
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Article: [No title information]

Blaser, Berenike Lisa / Weymar, Mathias / Wendt, Julia

PPmP - Psychotherapie · Psychosomatik · Medizinische Psychologie

2023 Volume 73, Issue 09/10, Page(s) 405–412

Abstract: Prämenstruelle Symptomatik ist eine weitverbreitete und dennoch wenig beforschte Problematik. Im deutschen Sprachraum existiert bislang kein Instrument zur Erhebung des breiten Spektrums an möglichen Symptomen und ...

Abstract	Prämenstruelle Symptomatik ist eine weitverbreitete und dennoch wenig beforschte Problematik. Im deutschen Sprachraum existiert bislang kein Instrument zur Erhebung des breiten Spektrums an möglichen Symptomen und deren Ausprägung. Aus diesem Grund wurden die Kurzversionen der Premenstrual Assessment Form mit 20 und 10 Items übersetzt und an einer Stichprobe von N=147 menstruierenden Personen validiert. Die internen Konsistenzen der 20er und 10er Item-Versionen sind hoch (Cronbachs α PAF20 =0,93 und α PAF10 =0,88) und vergleichbar mit den Originalversionen. Eine Faktorenanalyse identifizierte zwei Skalen, die psychologische und physiologische Symptomatik erfassen. Konvergente Validität wird durch den Zusammenhang mit dem PMS-Impact Questionnaire (r PAF20 =0,66, p<.001) belegt. Dieser ist signifikant höher (z=2.67, p=0,004) als der Zusammenhang mit dem Brief Symptom Inventory-18 (r PAF20 =0,50, p<.001), wodurch die divergente Validität als gegeben angenommen wird. Es wurden außerdem Cut-Off Werte für Verdachtsdiagnosen auf Basis der Diagnosekriterien des DSM-V für beide Kurzformen berechnet. Die übersetzte Premenstrual Assessment Form ist ein valides, reliables, ökonomisches und flexibel einsetzbares Instrument. Es eignet sich zur Quantifizierung prämenstrueller Symptomatik in der Forschung.
Keywords	Prämenstruelles Syndrom ; Prämenstruelle dysphorische Störung ; Fragebogen ; Gütekriterien ; Menstruation ; premenstrual syndrome ; premenstrual dysphoric disorder ; questionnaire ; psychometric properties ; menstruation
Language	German
Publishing date	2023-08-24
Publisher	Georg Thieme Verlag KG
Publishing place	Stuttgart ; New York
Document type	Article
ZDB-ID	800571-0
ISSN	1439-1058 ; 0937-2032 ; 0173-7937
ISSN (online)	1439-1058
ISSN	0937-2032 ; 0173-7937
DOI	10.1055/a-2136-6941
Database	Thieme publisher's database

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Article ; Online: The incidences of acute mesenteric ischaemia vary greatly depending on the population and diagnostic activity.

Reintam Blaser, Annika / Tamme, Kadri / Starkopf, Joel / Forbes, Alastair / Murruste, Marko / Talving, Peep / Acosta, Stefan / Björck, Martin

Critical care (London, England)

2024 Volume 28, Issue 1, Page(s) 85

MeSH term(s)	Humans ; Mesenteric Ischemia/diagnosis ; Incidence ; Prospective Studies ; Acute Disease
Language	English
Publishing date	2024-03-18
Publishing country	England
Document type	Letter ; Comment
ZDB-ID	2041406-7
ISSN	1466-609X ; 1364-8535
ISSN (online)	1466-609X
ISSN	1364-8535
DOI	10.1186/s13054-024-04870-x
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Article ; Online: The gut in COVID-19.

Reintam Blaser, Annika / Gunst, Jan / Arabi, Yaseen M

Intensive care medicine

2021 Volume 47, Issue 9, Page(s) 1024–1027

MeSH term(s)	COVID-19 ; Gastrointestinal Microbiome ; Humans ; SARS-CoV-2 ; Severity of Illness Index
Language	English
Publishing date	2021-07-08
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	80387-x
ISSN	1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
ISSN (online)	1432-1238
ISSN	0340-0964 ; 0342-4642 ; 0935-1701
DOI	10.1007/s00134-021-06461-8
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Article ; Online: Deepening of sedation with propofol has limited effect on intra-abdominal pressure - An interventional study in mechanically ventilated adult patients with intra-abdominal hypertension.

Padar, Martin / Starkopf, Joel / Reintam Blaser, Annika

Journal of critical care

2021 Volume 65, Page(s) 98–103

Abstract: Purpose: To evaluate the effect of deepening of sedation on intra-abdominal pressure (IAP).: Methods: 37 adult mechanically ventilated ICU patients with intra-abdominal hypertension received a bolus dose and subsequent infusion of propofol (bolus: 1 ... ...

Abstract	Purpose: To evaluate the effect of deepening of sedation on intra-abdominal pressure (IAP). Methods: 37 adult mechanically ventilated ICU patients with intra-abdominal hypertension received a bolus dose and subsequent infusion of propofol (bolus: 1 mg/kg, infusion: 3 mg/kg/h). IAP, mean arterial pressure (MAP), abdominal perfusion pressure (APP), depth of sedation according to Richmond Agitation-Sedation Scale (RASS), respiratory parameters, and vasopressor dose were assessed after bolus and at 15, 30 and 60 min of infusion of propofol. Results: Median IAP at baseline was 15 (13-16) mm Hg. During the intervention, median IAP decreased by 1 mm Hg at all time points. In 24% of patients IAP decreased by ≥3 mm Hg. Compared to baseline, MAP and APP were reduced at all time points. Deepening of sedation per RASS was achieved in 70% of patients at all time points. No changes in respiratory tidal volumes nor plateau pressures were observed. Vasopressor therapy with noradrenaline was started or increased in 43% of patients, whereas the increase in patients already receiving noradrenaline prior to the intervention was not significant. Conclusions: Deepening of sedation with propofol results in a small decrease in IAP and greater simultaneous decrease in MAP and APP, requiring increased vasopressor support in some cases.
MeSH term(s)	Adult ; Anesthesia ; Humans ; Intra-Abdominal Hypertension ; Propofol ; Respiration, Artificial
Chemical Substances	Propofol (YI7VU623SF)
Language	English
Publishing date	2021-05-28
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	632818-0
ISSN	1557-8615 ; 0883-9441
ISSN (online)	1557-8615
ISSN	0883-9441
DOI	10.1016/j.jcrc.2021.05.015
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Book ; Online: On the complexity of evaluating highest weight vectors

Bläser, Markus / Dörfler, Julian / Ikenmeyer, Christian

2020

Abstract: ... through algebraic geometry and representation theory. Originally Mulmuley and Sohoni proposed (SIAM J Comput 2001 ...

Abstract	Geometric complexity theory (GCT) is an approach towards separating algebraic complexity classes through algebraic geometry and representation theory. Originally Mulmuley and Sohoni proposed (SIAM J Comput 2001, 2008) to use occurrence obstructions to prove Valiant's determinant vs permanent conjecture, but recently B\"urgisser, Ikenmeyer, and Panova (Journal of the AMS 2019) proved this impossible. However, fundamental theorems of algebraic geometry and representation theory grant that every lower bound in GCT can be proved by the use of so-called highest weight vectors (HWVs). In the setting of interest in GCT (namely in the setting of polynomials) we prove the NP-hardness of the evaluation of HWVs in general, and we give efficient algorithms if the treewidth of the corresponding Young-diagram is small, where the point of evaluation is concisely encoded as a noncommutative algebraic branching program! In particular, this gives a large new class of separating functions that can be efficiently evaluated at points with low (border) Waring rank. Comment: 27 pages, full version
Keywords	Computer Science - Computational Complexity ; Mathematics - Combinatorics ; Mathematics - Representation Theory ; 68Q17 ; 68W30 ; 14Q15 ; I.1.2
Subject code	516
Publishing date	2020-02-26
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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