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  1. Article: Research progress on genetic control of host susceptibility to tuberculosis.

    Hu, Wenjuan / Xu, Kaijin

    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences

    2023  Volume 51, Issue 6, Page(s) 679–690

    Abstract: The "Lübeck disaster", twins studies, adoptees studies, and other epidemiological observational studies have shown that host genetic factors play a significant role in determining the host susceptibility ... ...

    Abstract The "Lübeck disaster", twins studies, adoptees studies, and other epidemiological observational studies have shown that host genetic factors play a significant role in determining the host susceptibility to
    MeSH term(s) Humans ; Genome-Wide Association Study ; Tuberculosis/genetics ; Gene Expression Regulation ; Cytokines/genetics ; Autoimmune Diseases ; Mycobacterium tuberculosis/genetics ; Genetic Predisposition to Disease
    Chemical Substances Cytokines
    Language English
    Publishing date 2023-03-09
    Publishing country China
    Document type Review ; Journal Article
    ISSN 1008-9292
    ISSN 1008-9292
    DOI 10.3724/zdxbyxb-2022-0484
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A Current Noise Cancellation Method Based on Fractional Linear Prediction for Bearing Fault Detection.

    Xu, Kaijin / Song, Xiangjin

    Sensors (Basel, Switzerland)

    2023  Volume 24, Issue 1

    Abstract: The stator current in an induction motor contains a large amount of information, which is unrelated to bearing faults. This information is considered as the noise component for the detection of bearing faults. When there is noise information in the ... ...

    Abstract The stator current in an induction motor contains a large amount of information, which is unrelated to bearing faults. This information is considered as the noise component for the detection of bearing faults. When there is noise information in the current signal, it can affect the detection of motor bearing faults and lead to the possibility of false alarms. Therefore, to accomplish an effective bearing fault detection, all or some of these noise components must be properly eliminated. This paper proposes the use of fractional linear prediction (FLP) as a noise elimination method in bearing fault diagnosis, which makes these noise components the predictable components and this bearing fault information the unpredictable components. The basis of the FLP is to eliminate noise components in the current signal by predicting predictable components through linear prediction theory and optimal prediction order. Meanwhile, this paper adopts the FLP model with limited memory samples. After determining the optimal number of memories, only the fractional derivative order parameter needs to be optimized, which greatly reduces the computational complexity and difficulty in parameter optimization. In addition, this paper uses spectral analysis of the current signals through experimental simulation to compare the FLP method with the linear prediction (LP) method and the time-shifting (TS) method that have been successfully applied to bearing fault diagnosis. Based on the analysis results, the FLP method can better extract fault features and achieve better bearing fault diagnosis results, verifying the effectiveness and superiority of the FLP method in the field of bearing fault diagnosis. Additionally, the predictive performance of thevFLP and LP was compared based on experimental data, verifying the advantages of the FLP method in predictive performance, indicating that this method has a better noise cancellation effect.
    Language English
    Publishing date 2023-12-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s24010052
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Corrigendum: Demineralized dentin matrix promotes gingival healing in alveolar ridge preservation of premolars extracted for orthodontic reason: a split-mouth study.

    Xu, Xiaofeng / Peng, Dongsheng / Zhou, Bowei / Lin, Kaijin / Wang, Siyi / Zhao, Wei / Zheng, Minqian / Yang, Jin / Guo, Jianbin

    Frontiers in endocrinology

    2024  Volume 14, Page(s) 1357769

    Abstract: This corrects the article DOI: 10.3389/fendo.2023.1281649.]. ...

    Abstract [This corrects the article DOI: 10.3389/fendo.2023.1281649.].
    Language English
    Publishing date 2024-01-16
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2023.1357769
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Progress on diagnosis and treatment of latent tuberculosis infection.

    Ying, Chiqing / He, Chang / Xu, Kaijin / Li, Yongtao / Zhang, Ying / Wu, Wei

    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences

    2023  Volume 51, Issue 6, Page(s) 691–696

    Abstract: One fourth of the global population has been infected ... ...

    Abstract One fourth of the global population has been infected with
    MeSH term(s) Humans ; Rifampin/therapeutic use ; Isoniazid/therapeutic use ; Latent Tuberculosis/diagnosis ; Latent Tuberculosis/drug therapy ; HIV Infections/epidemiology ; Antitubercular Agents/therapeutic use
    Chemical Substances Rifampin (VJT6J7R4TR) ; Isoniazid (V83O1VOZ8L) ; Antitubercular Agents
    Language English
    Publishing date 2023-03-11
    Publishing country China
    Document type Journal Article
    ISSN 1008-9292
    ISSN 1008-9292
    DOI 10.3724/zdxbyxb-2022-0445
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Identification of essential oils with strong activity against stationary phase

    Cao, Dan / Jiang, Xiuzhi / Wu, Tiantian / Xiang, Yanghui / Liu, Jiaying / Li, Zhen / Yuan, Xin / Bi, Kefan / Dong, Xu / Tønjum, Tone / Xu, Kaijin / Zhang, Ying

    Heliyon

    2024  Volume 10, Issue 5, Page(s) e27073

    Abstract: Purpose: To identify essential oils (EOs) active against non-growing stationary phase : Methods: The activity of EOs against both stationary and log phase : Results: We assessed the activity of 80 EOs against stationary phase : Conclusions: Our ...

    Abstract Purpose: To identify essential oils (EOs) active against non-growing stationary phase
    Methods: The activity of EOs against both stationary and log phase
    Results: We assessed the activity of 80 EOs against stationary phase
    Conclusions: Our study indicates that some EOs display outstanding effectiveness against both drug susceptible
    Language English
    Publishing date 2024-02-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e27073
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Long Non-coding RNA MALAT1: A Key Player in Liver Diseases.

    Lu, Juan / Guo, Jing / Liu, Jun / Mao, Xiaomin / Xu, Kaijin

    Frontiers in medicine

    2022  Volume 8, Page(s) 734643

    Abstract: Long non-coding RNAs (lncRNAs) exceed 200 nucleotides in length are considered to be involved in both developmental processes and various diseases. Here, we focus on lncRNA MALAT1 (metastasis-associated lung adenocarcinoma transcript 1), which was one of ...

    Abstract Long non-coding RNAs (lncRNAs) exceed 200 nucleotides in length are considered to be involved in both developmental processes and various diseases. Here, we focus on lncRNA MALAT1 (metastasis-associated lung adenocarcinoma transcript 1), which was one of the most important lncRNAs in proliferation, apoptosis, and migration. MALAT1 plays a regulatory role in liver diseases, including hepatic fibrosis, liver regeneration, liver cancer, and fatty liver diseases. In the current review, we summarize the latest literature about the function roles of MALAT1 in liver disorders. Probing the regulatory mechanism and cross talk of MALAT1 with other signaling pathways of pathological processes would improve the prognosis, diagnosis of liver diseases, and offer a promising candidate target for therapeutic interventions.
    Language English
    Publishing date 2022-01-25
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2021.734643
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Long Non-coding RNA MALAT1

    Juan Lu / Jing Guo / Jun Liu / Xiaomin Mao / Kaijin Xu

    Frontiers in Medicine, Vol

    A Key Player in Liver Diseases

    2022  Volume 8

    Abstract: Long non-coding RNAs (lncRNAs) exceed 200 nucleotides in length are considered to be involved in both developmental processes and various diseases. Here, we focus on lncRNA MALAT1 (metastasis-associated lung adenocarcinoma transcript 1), which was one of ...

    Abstract Long non-coding RNAs (lncRNAs) exceed 200 nucleotides in length are considered to be involved in both developmental processes and various diseases. Here, we focus on lncRNA MALAT1 (metastasis-associated lung adenocarcinoma transcript 1), which was one of the most important lncRNAs in proliferation, apoptosis, and migration. MALAT1 plays a regulatory role in liver diseases, including hepatic fibrosis, liver regeneration, liver cancer, and fatty liver diseases. In the current review, we summarize the latest literature about the function roles of MALAT1 in liver disorders. Probing the regulatory mechanism and cross talk of MALAT1 with other signaling pathways of pathological processes would improve the prognosis, diagnosis of liver diseases, and offer a promising candidate target for therapeutic interventions.
    Keywords lncRNAs ; MALAT1 ; mechanism ; signaling pathways ; liver diseases ; Medicine (General) ; R5-920
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Determination of Age- and Sex-Specific 99th Percentile Upper Reference Limits for High-Sensitivity Cardiac Troponin I in Healthy Chinese Adults.

    He, Bing / Wang, Kaijin / Xu, Panyang / Zhou, Qi / Xu, Jiancheng

    Cardiology

    2022  Volume 147, Issue 3, Page(s) 261–270

    Abstract: Introduction: Age- and sex-specific reference intervals (RIs) for high-sensitivity cardiac troponin I (hs-cTnI) are not available in China. The objective of the present research was to determine the assay-specific 99th percentile upper reference limits ( ...

    Abstract Introduction: Age- and sex-specific reference intervals (RIs) for high-sensitivity cardiac troponin I (hs-cTnI) are not available in China. The objective of the present research was to determine the assay-specific 99th percentile upper reference limits (URLs) for hs-cTnI in healthy Chinese adults.
    Methods: Apparently healthy individuals were first screened with a questionnaire. The reference population was selected according to the International Federation of Clinical Chemistry (IFCC) criteria using surrogate biomarker for diabetes, myocardial dysfunction, and renal dysfunction. The serum concentration of hs-cTnI was measured using the automatized VITROS 5600 Immunodiagnostic system (Ortho Clinical Diagnostics, Raritan, NJ, USA).
    Results: A total of 2,183 healthy individuals (1,051 men and 1,132 women aged from 20 to 95 years) were enrolled in the study. The serum overall 99th percentile URLs of hs-cTnI were 11.1 ng/L (12.5 ng/L in men, 9.6 ng/L in women). In both men and women, the 99th percentile URLs were significantly higher in individuals ≥55 years old than those in the <55 years old, especially in women. Moreover, 78.8% of males and 70.1% of females presented with hs-cTnI concentrations above the limit of detection of 0.43 ng/L.
    Conclusion: The hs-cTnI-VITROS assay coincided with the performance standard of the IFCC for high-sensitivity cTnI assays. The 99th percentile URLs for hs-cTnI in healthy Chinese adults were different from the manufacturer declared and appeared heterogeneous, potentially susceptible to factors such as age and sex.
    MeSH term(s) Adult ; Age Factors ; Asians ; Biomarkers/blood ; China ; Female ; Humans ; Male ; Middle Aged ; Reference Values ; Sensitivity and Specificity ; Sex Factors ; Troponin I/blood
    Chemical Substances Biomarkers ; Troponin I
    Language English
    Publishing date 2022-02-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 80092-2
    ISSN 1421-9751 ; 0008-6312
    ISSN (online) 1421-9751
    ISSN 0008-6312
    DOI 10.1159/000523721
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Assessment of the correlation between supracrestal gingival tissue dimensions and other periodontal phenotypes components via the digital registration method: a cross‑sectional study in a Chinese population.

    Lin, Kaijin / Wang, Siyi / Xu, Xiaofeng / Yu, Lu / Pan, Rui / Zheng, Minqian / Yang, Jin / Guo, Jianbin

    BMC oral health

    2024  Volume 24, Issue 1, Page(s) 408

    Abstract: Background: Supracrestal gingival tissue dimensions (SGTDs) has been considered to be an essential element of periodontal phenotype (PP) components. This study aimed to explore the relationship between SGTDs and other PP components by digital ... ...

    Abstract Background: Supracrestal gingival tissue dimensions (SGTDs) has been considered to be an essential element of periodontal phenotype (PP) components. This study aimed to explore the relationship between SGTDs and other PP components by digital superposition method that integrated cone beam computed tomography (CBCT) with intraoral scanning.
    Methods: This cross-sectional study was conducted at the Stomatology Hospital of Fujian Medical University. Participants were recruited based on the inclusion and exclusion criteria. The data obtained from the digital scanner (TRIOS 3, 3Shape, Denmark) and CBCT images were imported into the TRIOS software (Implant Studio, 3Shape, Denmark) for computing relevant parameters. The significant level was set at 0.05.
    Results: A total of 83 participants with 498 maxillary anterior teeth were finally included. The mean values of supracrestal gingival height (SGH) and the distance from the cementoenamel junction (CEJ) to the crest of the alveolar ridge (CEJ-ABC) on the buccal site were significantly higher than palatal SGH (SGH-p) and palatal CEJ-ABC (CEJ-ABC-p). Men exhibited taller CEJ-ABC and SGH-p than women. Additionally, tooth type was significantly associated with the SGH, SGH-p and CEJ-ABC-p. Taller SGH was associated with wider crown, smaller papilla height (PH), flatter gingival margin, thicker bone thickness (BT) and gingival thickness (GT) at CEJ, the alveolar bone crest (ABC), and 2 mm apical to the ABC. Smaller SGH-p displayed thicker BT and GT at CEJ, the ABC, and 2 and 4 mm apical to the ABC. Higher CEJ-ABC showed lower interproximal bone height, smaller PH, flatter gingival margin, thinner GT and BT at CEJ, and 2 mm apical to the ABC. Smaller CEJ-ABC-p displayed thicker BT at CEJ and 2 and 4 mm apical to the ABC. On the buccal, thicker GT was correlated with thicker BT at 2 and 4 mm below the ABC.
    Conclusion: SGTDs exhibited a correlation with other PP components, especially crown shape, gingival margin and interdental PH. The relationship between SGTDs and gingival and bone phenotypes depended on the apico-coronal level evaluated.
    Trial registration: This study was approved by the Biomedical Research Ethics Committee of Stomatology Hospital of Fujian Medical University (approval no. 2023-24).
    MeSH term(s) Male ; Humans ; Female ; Cross-Sectional Studies ; Maxilla/diagnostic imaging ; Gingiva/diagnostic imaging ; Tooth Crown ; Cone-Beam Computed Tomography/methods ; China ; Breast Cyst
    Language English
    Publishing date 2024-04-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2091511-1
    ISSN 1472-6831 ; 1472-6831
    ISSN (online) 1472-6831
    ISSN 1472-6831
    DOI 10.1186/s12903-024-04158-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Oral Bacteria Dysbiosis in Patients with Linezolid-Induced Black Hairy Tongue: A Case Series.

    Shangguan, Yanwan / Ji, Zhongkang / Guo, Wanru / Hu, Wenjuan / Li, Xiaomeng / Xu, Kaijin

    Infection and drug resistance

    2022  Volume 15, Page(s) 5449–5454

    Abstract: Linezolid-induced black hairy tongue is a self-limiting benign disease that is rare. Here, we report three patients who developed black hairy tongue after linezolid treatment. The severe dysbiosis of oral bacterial communities was observed in all these ... ...

    Abstract Linezolid-induced black hairy tongue is a self-limiting benign disease that is rare. Here, we report three patients who developed black hairy tongue after linezolid treatment. The severe dysbiosis of oral bacterial communities was observed in all these patients. Proteobacteria was the most prevalent phylum (over 90%) at the black tongue stage. Furthermore, the dramatic oral bacterial alteration took a long time to reverse after the BHT resolved.
    Language English
    Publishing date 2022-09-14
    Publishing country New Zealand
    Document type Case Reports
    ZDB-ID 2494856-1
    ISSN 1178-6973
    ISSN 1178-6973
    DOI 10.2147/IDR.S373266
    Database MEDical Literature Analysis and Retrieval System OnLINE

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