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  1. Article ; Online: Reply to "Further insight into data interpretation and conclusions".

    Roche, Madonna

    Journal of clinical & translational endocrinology

    2015  Volume 2, Issue 2, Page(s) 84

    Language English
    Publishing date 2015-02-24
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2834222-7
    ISSN 2214-6237 ; 2214-6237
    ISSN (online) 2214-6237
    ISSN 2214-6237
    DOI 10.1016/j.jcte.2015.01.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Factors associated with a diabetes diagnosis and late diabetes diagnosis for males and females.

    Roche, Madonna M / Wang, Peizhong Peter

    Journal of clinical & translational endocrinology

    2014  Volume 1, Issue 3, Page(s) 77–84

    Abstract: Aims: To examine the factors associated with diabetes, a late diabetes diagnosis, and whether these factors are different for males and females.: Methods: Cross-sectional study including 7101 individuals aged ≥25 years in Newfoundland and Labrador, ... ...

    Abstract Aims: To examine the factors associated with diabetes, a late diabetes diagnosis, and whether these factors are different for males and females.
    Methods: Cross-sectional study including 7101 individuals aged ≥25 years in Newfoundland and Labrador, Canada (466 with diabetes; 332 diagnosed late). Logistic regression analysis was used to determine the factors associated with a diabetes diagnosis and late diabetes diagnosis.
    Results: For males, overweight/obesity (HR, 1.35; 95% CI, 1.06-1.72) was positively associated with diabetes while being a regular/occasional drinker (HR, 0.53; 95% CI, 0.32-0.88) was inversely associated with diabetes. Living in a rural area (HR, 1.47; 95% CI, 1.01-2.15), receiving social assistance (HR, 2.80; 95% CI, 1.52-5.15), having poor self perceived health (HR, 2.06; 95% CI, 1.32-3.21), and considering most days stressful (HR, 1.45; 95% CI, 1.01-2.10) were positively associated with diabetes for females. No factors were significantly associated with a late diabetes diagnosis for males. Having a low education (OR, 0.33; 95% CI, 0.11-0.99) was inversely associated with a late diabetes diagnosis for females.
    Conclusions: Different factors are associated with diabetes for males and females. Disadvantaged females appear to be at the greatest risk. The factors associated with a late diabetes diagnosis were also different for males and females. Females with lower education levels are diagnosed with diabetes earlier than females with higher education levels. Certain risk factors appear to impact males and females differently and more research is needed on how males and females develop diabetes and when they are diagnosed.
    Language English
    Publishing date 2014-07-08
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2834222-7
    ISSN 2214-6237 ; 2214-6237
    ISSN (online) 2214-6237
    ISSN 2214-6237
    DOI 10.1016/j.jcte.2014.07.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Sex differences in all-cause and cardiovascular mortality, hospitalization for individuals with and without diabetes, and patients with diabetes diagnosed early and late.

    Roche, Madonna M / Wang, Peizhong Peter

    Diabetes care

    2013  Volume 36, Issue 9, Page(s) 2582–2590

    Abstract: Objective: To compare risk of all-cause mortality, cardiovascular disease (CVD) mortality, acute myocardial infarction (AMI) mortality, stroke mortality, and hospitalizations for males and females with and without diabetes and those with diabetes ... ...

    Abstract Objective: To compare risk of all-cause mortality, cardiovascular disease (CVD) mortality, acute myocardial infarction (AMI) mortality, stroke mortality, and hospitalizations for males and females with and without diabetes and those with diabetes diagnosed early and late.
    Research design and methods: We conducted a population-based retrospective cohort study including 73,783 individuals aged 25 years or older in Newfoundland and Labrador, Canada (15,152 with diabetes; 9,517 with late diagnoses).
    Results: Males and females with diabetes had an increased risk of all-cause mortality, CVD mortality, AMI mortality, and CVD hospitalizations compared with individuals without diabetes, and the risk was stronger in females than in males. For females, risks of all-cause mortality (hazard ratio [HR] 1.85 [95% CI 1.74-1.96]) and CVD hospitalizations (2.57 [2.24-2.94]) were significantly higher compared with their male counterparts (1.59 [1.51-1.69] and 1.92 [1.72-2.14]). Females with diabetes diagnosed late had an increased risk of CVD mortality (6.54 [4.80-8.91]) and CVD hospitalizations (5.22 [4.31-6.33]) compared with females without diabetes, and both were significantly higher compared with their male counterparts (3.44 [2.47-4.79]) and (3.33 [2.80-3.95]).
    Conclusions: Females with diabetes have a greater risk of mortality than males with diabetes. CVD has a greater impact on females with diabetes than males, especially when diagnosed at a later stage. Different management strategies should be considered for males and females and those with early and late diagnoses of diabetes.
    MeSH term(s) Aged ; Cardiovascular Diseases/mortality ; Cause of Death ; Diabetes Mellitus, Type 2 ; Female ; Hospitalization ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Sex Factors
    Language English
    Publishing date 2013-04-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 441231-x
    ISSN 1935-5548 ; 0149-5992
    ISSN (online) 1935-5548
    ISSN 0149-5992
    DOI 10.2337/dc12-1272
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
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  4. Article ; Online: Diabetes and sex-specific colorectal cancer risks in Newfoundland and Labrador: a population-based retrospective cohort study.

    Sikdar, Khokan C / Walsh, Stephanie J / Roche, Madonna / Jiang, Ying / Syrowatka, Ania / Collins, Kayla D

    Canadian journal of public health = Revue canadienne de sante publique

    2013  Volume 104, Issue 2, Page(s) e101–7

    Abstract: Objective: Studies on the relationship between diabetes and colorectal cancer (CRC) are inconsistent. It is also unclear whether CRC risk elevation for individuals with diabetes is similar for males and females. Using data from Newfoundland and Labrador ...

    Abstract Objective: Studies on the relationship between diabetes and colorectal cancer (CRC) are inconsistent. It is also unclear whether CRC risk elevation for individuals with diabetes is similar for males and females. Using data from Newfoundland and Labrador (NL), the province with the highest CRC incidence and diabetes prevalence in Canada, we assessed and compared the risk elevation of CRC for males and females with diabetes, overall and by anatomic subsite.
    Methods: A population-based retrospective cohort study including a study sample of 122,228 individuals aged ≥30 years was conducted using administrative health databases over a 10.5-year period (October 1, 1996 to March 31, 2007). Hazard ratios were estimated using Cox proportional hazard models.
    Results: In comparison with non-diabetes counterparts, both males and females with diabetes were at a significantly elevated risk of overall CRC, with corresponding hazard ratios of 1.38 and 1.52, respectively. For males, diabetes significantly increased the risk of proximal and distal colon cancers, but not of rectal cancer. For females, diabetes significantly increased the risk of proximal colon and rectal cancers, but not of distal colon cancer. The results suggest that there is a stronger association between diabetes and CRC for females than for males, and the association did not change after adjusting for overweight/obesity.
    Conclusions: Diabetes led to a greater risk of CRC in both the male and female population in NL. Risk was subsite-specific and varied by sex. Future research should examine reasons for the observed diabetes-associated CRC risk to support CRC prevention strategies among the diabetes population.
    MeSH term(s) Adult ; Aged ; Colorectal Neoplasms/epidemiology ; Comorbidity ; Databases, Factual ; Diabetes Mellitus/epidemiology ; Female ; Humans ; Male ; Middle Aged ; Newfoundland and Labrador/epidemiology ; Retrospective Studies ; Risk Factors ; Sex Distribution
    Language English
    Publishing date 2013-02-25
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 417262-0
    ISSN 1920-7476 ; 0008-4263
    ISSN (online) 1920-7476
    ISSN 0008-4263
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 81: Show issues Location:
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  5. Article: [Apropos of 4 cases of poisoning by phosphene].

    ROCHE, L / LEJEUNE, E / MADONNA / ROBERT, J M / LACHIEZE-REY

    Archives des maladies professionnelles de medecine du travail et de securite sociale

    1961  Volume 22, Page(s) 52–55

    MeSH term(s) Phosphates/toxicity ; Phosphenes ; Vision Disorders
    Chemical Substances Phosphates
    Language French
    Publishing date 1961-01
    Publishing country France
    Document type Journal Article
    ZDB-ID 211572-4
    ISSN 0003-9691 ; 1250-3274
    ISSN 0003-9691 ; 1250-3274
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Un I Zs.418: Show issues Location:
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