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  1. Article ; Online: In vitro release of aluminum from the geophagic clay "Chacco" in the Peruvian highlands: Chemical characterization and health risk assessment.

    Choquenaira-Quispe, Celia / Yucra Condori, Harry R / Villanueva Salas, José A / Gonzales-Condori, Elvis Gilmar

    Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes

    2023  Volume 58, Issue 4, Page(s) 294–303

    Abstract: In the altiplano zone of Latin America, "Chacco" is one of the clays widely consumed as part of geophagy. The objectives of the study were to chemically characterize "Chacco", determine the zero charge point, evaluate the release of aluminum in vitro, ... ...

    Abstract In the altiplano zone of Latin America, "Chacco" is one of the clays widely consumed as part of geophagy. The objectives of the study were to chemically characterize "Chacco", determine the zero charge point, evaluate the release of aluminum in vitro, perform the kinetic study and evaluate the health risk. The results by ICP-OES showed that the elements with the highest concentration were Al, Ba, Ca, Fe, K, Mg, Mn, Na, Si, Sr, Ti and Zn. ATR-FTIR analysis showed the presence of Si-O (693 and 990 cm
    MeSH term(s) Humans ; Clay ; Aluminum ; Pica ; Peru ; Risk Assessment
    Chemical Substances Clay (T1FAD4SS2M) ; Aluminum (CPD4NFA903)
    Language English
    Publishing date 2023-01-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 197072-0
    ISSN 1532-4109 ; 0360-1234
    ISSN (online) 1532-4109
    ISSN 0360-1234
    DOI 10.1080/03601234.2022.2161795
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: In vitro release of aluminum from the geophagic clay "Chacco" in the Peruvian highlands: Chemical characterization and health risk assessment

    Choquenaira-Quispe, Celia / Yucra Condori, Harry R. / Villanueva Salas, José A. / Gonzales-Condori, Elvis Gilmar

    Journal of Environmental Science and Health, Part B. 2023 Apr. 3, v. 58, no. 4 p.294-303

    2023  

    Abstract: In the altiplano zone of Latin America, "Chacco" is one of the clays widely consumed as part of geophagy. The objectives of the study were to chemically characterize "Chacco", determine the zero charge point, evaluate the release of aluminum in vitro, ... ...

    Abstract In the altiplano zone of Latin America, "Chacco" is one of the clays widely consumed as part of geophagy. The objectives of the study were to chemically characterize "Chacco", determine the zero charge point, evaluate the release of aluminum in vitro, perform the kinetic study and evaluate the health risk. The results by ICP-OES showed that the elements with the highest concentration were Al, Ba, Ca, Fe, K, Mg, Mn, Na, Si, Sr, Ti and Zn. ATR-FTIR analysis showed the presence of Si-O (693 and 990 cm⁻¹), Al-O (790 cm⁻¹), Al-Al-OH bending vibration (912 cm⁻¹), Si-H bond stretching (2100 to 2500 cm⁻¹) and free -OH groups (3629 cm⁻¹). SEM-EDX results indicate that Al is one of the main constituents of "Chacco" (7.35 wt%). The pHzpc of "Chacco" was 6.83. In the dissolution profiles, the highest Al release occurred at pH 6.8 and in intestinal juice simulated with pseudo-second order dissolution kinetics. The EDIAₗ and EWIAₗ were 20.24 and 142.66 respectively, comparing EWIAₗ with the PTWI established by JECFA (2 mg/kg bw), it is concluded that the weekly intake of "Chacco" represents an appreciable health risk. There are no reports of the carcinogenic factor of Al, so TRAₗ was not calculated.
    Keywords aluminum ; carcinogens ; clay ; environmental science ; geophagia ; health effects assessments ; intestinal secretions ; pH ; risk ; vibration ; Latin America ; Chacco ; Geophagy ; health risk
    Language English
    Dates of publication 2023-0403
    Size p. 294-303.
    Publishing place Taylor & Francis
    Document type Article ; Online
    ZDB-ID 197072-0
    ISSN 1532-4109 ; 0360-1234
    ISSN (online) 1532-4109
    ISSN 0360-1234
    DOI 10.1080/03601234.2022.2161795
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  3. Article: Typical environmental factors of high-altitude areas: Possible inactivation mechanisms of severe acute respiratory syndrome coronavirus 2.

    Ramirez, J Kenedy / Saldaña-Bobadilla, Vanessa / Choquenaira-Quispe, Celia

    Medical journal, Armed Forces India

    2020  Volume 77, Page(s) S525–S526

    Language English
    Publishing date 2020-12-28
    Publishing country India
    Document type Journal Article
    ZDB-ID 196342-9
    ISSN 0377-1237
    ISSN 0377-1237
    DOI 10.1016/j.mjafi.2020.09.015
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  4. Article ; Online: Factors involved in low susceptibility to COVID-19: An adaptation of high altitude inhabitants.

    Choquenaira-Quispe, Celia / Saldaña-Bobadilla, Vanessa / Ramirez, J Kenedy

    Medical hypotheses

    2020  Volume 143, Page(s) 110068

    MeSH term(s) Altitude ; Angiotensin-Converting Enzyme 2 ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Disease Progression ; Disease Susceptibility ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Interleukin-6/metabolism ; Lung/physiology ; Pandemics ; Peptidyl-Dipeptidase A/metabolism ; Pneumonia, Viral/epidemiology ; Prognosis ; SARS-CoV-2
    Chemical Substances HIF1A protein, human ; Hypoxia-Inducible Factor 1, alpha Subunit ; IL6 protein, human ; Interleukin-6 ; Peptidyl-Dipeptidase A (EC 3.4.15.1) ; ACE2 protein, human (EC 3.4.17.23) ; Angiotensin-Converting Enzyme 2 (EC 3.4.17.23)
    Keywords covid19
    Language English
    Publishing date 2020-07-02
    Publishing country United States
    Document type Letter
    ZDB-ID 193145-3
    ISSN 1532-2777 ; 0306-9877
    ISSN (online) 1532-2777
    ISSN 0306-9877
    DOI 10.1016/j.mehy.2020.110068
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  5. Article ; Online: Quantification and health risk assessment of lead and cadmium in wheat, rice, and their processed products from Peru.

    Choquenaira-Quispe, Celia / Angulo Vargas, Sheyla J / Rojas-Tamata, Karen / Yucra Condori, Harry R / Villanueva Salas, José A

    Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes

    2022  Volume 57, Issue 4, Page(s) 297–304

    Abstract: In Peru, rice grains, wheat, and their processed products are accessible due to their low cost; however, their sale does not have quality certification, so their safety is not guaranteed. This study quantified lead (Pb) and cadmium (Cd) by voltammetry in ...

    Abstract In Peru, rice grains, wheat, and their processed products are accessible due to their low cost; however, their sale does not have quality certification, so their safety is not guaranteed. This study quantified lead (Pb) and cadmium (Cd) by voltammetry in 16 samples of grains and processed products from four markets in Arequipa (Altiplano, Andrés Avelino Cáceres, Los Incas, and San Camilo) and evaluated their potential health risk. The maximum concentrations of Pb in rice, wheat, and their processed products were 4.821 mg/kg, 7.962 mg/kg, 4.717 mg/kg, and 6.440 mg/kg, respectively; only seven samples showed Cd. All samples exceeded the maximum level (ML) for Pb, and four samples exceeded the ML for Cd established by the Codex Alimentarius (0.200 mg/kg); the rice product had the highest concentration of Pb and Cd. In relation to the estimation of potential health risk, the estimated daily intake (EDI), target hazard quotient (THQ), and target cancer risk (TR), showed that the consumption of all processed rice and wheat products (except Andrés Avelino Cáceres rice and San Camilo wheat) represent a health threat associated with an increased probability of cancer development.
    MeSH term(s) Cadmium/analysis ; Cadmium/toxicity ; Environmental Monitoring ; Food Contamination/analysis ; Humans ; Lead/toxicity ; Metals, Heavy/analysis ; Neoplasms ; Oryza ; Peru ; Risk Assessment ; Soil Pollutants/analysis ; Soil Pollutants/toxicity ; Triticum
    Chemical Substances Metals, Heavy ; Soil Pollutants ; Cadmium (00BH33GNGH) ; Lead (2P299V784P)
    Language English
    Publishing date 2022-03-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 197072-0
    ISSN 1532-4109 ; 0360-1234
    ISSN (online) 1532-4109
    ISSN 0360-1234
    DOI 10.1080/03601234.2022.2049152
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  6. Article: Quantification and health risk assessment of lead and cadmium in wheat, rice, and their processed products from Peru

    Choquenaira-Quispe, Celia / Angulo Vargas, Sheyla J. / Rojas-Tamata, Karen / Yucra Condori, Harry R. / Villanueva Salas, José A.

    Journal of environmental science and health. 2022 Apr. 3, v. 57, no. 4

    2022  

    Abstract: In Peru, rice grains, wheat, and their processed products are accessible due to their low cost; however, their sale does not have quality certification, so their safety is not guaranteed. This study quantified lead (Pb) and cadmium (Cd) by voltammetry in ...

    Abstract In Peru, rice grains, wheat, and their processed products are accessible due to their low cost; however, their sale does not have quality certification, so their safety is not guaranteed. This study quantified lead (Pb) and cadmium (Cd) by voltammetry in 16 samples of grains and processed products from four markets in Arequipa (Altiplano, Andrés Avelino Cáceres, Los Incas, and San Camilo) and evaluated their potential health risk. The maximum concentrations of Pb in rice, wheat, and their processed products were 4.821 mg/kg, 7.962 mg/kg, 4.717 mg/kg, and 6.440 mg/kg, respectively; only seven samples showed Cd. All samples exceeded the maximum level (ML) for Pb, and four samples exceeded the ML for Cd established by the Codex Alimentarius (0.200 mg/kg); the rice product had the highest concentration of Pb and Cd. In relation to the estimation of potential health risk, the estimated daily intake (EDI), target hazard quotient (THQ), and target cancer risk (TR), showed that the consumption of all processed rice and wheat products (except Andrés Avelino Cáceres rice and San Camilo wheat) represent a health threat associated with an increased probability of cancer development.
    Keywords Codex Alimentarius ; average daily intake ; carcinogenesis ; certification ; environmental science ; health effects assessments ; rice ; risk ; voltammetry ; wheat ; Peru
    Language English
    Dates of publication 2022-0403
    Size p. 297-304.
    Publishing place Taylor & Francis
    Document type Article
    ZDB-ID 197072-0
    ISSN 1532-4109 ; 0360-1234
    ISSN (online) 1532-4109
    ISSN 0360-1234
    DOI 10.1080/03601234.2022.2049152
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 4528: Show issues

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  7. Article: Factors involved in low susceptibility to COVID-19: An adaptation of high altitude inhabitants

    Choquenaira-Quispe, Celia / Saldaña-Bobadilla, Vanessa / Ramirez, J Kenedy

    Med Hypotheses

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #624597
    Database COVID19

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  8. Article ; Online: Factors involved in low susceptibility to COVID-19

    Choquenaira-Quispe, Celia / Saldaña-Bobadilla, Vanessa / Ramirez, J. Kenedy

    Medical Hypotheses

    An adaptation of high altitude inhabitants

    2020  Volume 143, Page(s) 110068

    Keywords General Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 193145-3
    ISSN 1532-2777 ; 0306-9877
    ISSN (online) 1532-2777
    ISSN 0306-9877
    DOI 10.1016/j.mehy.2020.110068
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Effect of preemptive photobiomodulation associated with nimesulide on the postsurgical outcomes, oxidative stress, and quality of life after third molar surgery: a randomized, split-mouth, controlled clinical trial.

    Cetira Filho, Edson Luiz / Silva, Paulo Goberlânio Barros / Wong, Deysi Viviana Tenazoa / Choquenaira-Quispe, Celia / Cesário, Francisco Rafael Alves Santana / de Sousa Nogueira, Gisele / de Sousa, Alan Vieira Costa / de Aguiar, Andréa Silvia Walter / da Cruz Fonseca, Said Goncalves / Costa, Fabio Wildson Gurgel

    Clinical oral investigations

    2022  Volume 26, Issue 12, Page(s) 6941–6960

    Abstract: Objective: The aim of this study is to compare the effect of photobiomodulation with low-level laser therapy (LLLT) and nimesulide on inflammatory parameters, biomarkers of oxidative stress and inflammation, and quality of life after lower third molar ( ... ...

    Abstract Objective: The aim of this study is to compare the effect of photobiomodulation with low-level laser therapy (LLLT) and nimesulide on inflammatory parameters, biomarkers of oxidative stress and inflammation, and quality of life after lower third molar (L3M) surgery.
    Material and methods: A randomized, two-factor, triple-blind, controlled, split-mouth clinical trial was performed with 40 volunteers who required bilateral L3M removal. Patients were allocated depending on the use or not of 100 mg nimesulide 1 hbefore surgery, as well as the use or not of LLLT in the preoperative period.
    Results: Pain peaks occurred after 6 h (nimesulide-placebo [N-P] group) and 8 h (nimesulide group). In the N-P group, LLLT resulted in significantly lower mean pain scores than the subgroup without LLLT after 4 h (p = 0.009) and 6 h (p = 0.048). As for edema, a shorter distance between the mandibular angle and the outer canthus of the eyes after 7 days (p = 0.037) and a smaller cumulative effect (p = 0.036) were observed in the N-P group associated with LLLT. A direct effect between LLLT (p = 0.047) and a reduction in the mean scores of overall dissatisfaction with quality of life was detected.
    Conclusions: Preemptive use of nimesulide only delayed peak pain. LLLT reduced edema, trismus, and contributed to a better perception of quality of life. Nimesulide inhibits peroxidation by increasing GSH and stopping neutrophil migration. The benefit of the association of both strategies was not superior to the use of LLLT alone.
    Clinical relevance: Translational study with impact on clinical-surgical protocols involving L3M surgery related to pharmacological and non-pharmacological methods.
    MeSH term(s) Humans ; Molar, Third/surgery ; Quality of Life ; Tooth, Impacted/surgery ; Tooth Extraction/adverse effects ; Trismus/etiology ; Low-Level Light Therapy/methods ; Edema/prevention & control ; Mouth ; Oxidative Stress ; Pain/etiology ; Pain, Postoperative/drug therapy ; Double-Blind Method
    Chemical Substances nimesulide (V4TKW1454M)
    Language English
    Publishing date 2022-08-11
    Publishing country Germany
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 1364490-7
    ISSN 1436-3771 ; 1432-6981
    ISSN (online) 1436-3771
    ISSN 1432-6981
    DOI 10.1007/s00784-022-04649-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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