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Article ; Online: Patients with traumatic brain injury are at high risk of developing chronic sleep-wake disturbances.

Gosselin, Nadia / Tellier, Myriam

Journal of neurology, neurosurgery, and psychiatry

2010 Volume 81, Issue 12, Page(s) 1297

MeSH term(s)	Brain Injury, Chronic/diagnosis ; Brain Injury, Chronic/epidemiology ; Cross-Sectional Studies ; Humans ; Post-Concussion Syndrome/diagnosis ; Post-Concussion Syndrome/epidemiology ; Risk Factors ; Sleep Disorders, Intrinsic/diagnosis ; Sleep Disorders, Intrinsic/epidemiology ; Sleep Initiation and Maintenance Disorders/diagnosis ; Sleep Initiation and Maintenance Disorders/epidemiology
Language	English
Publishing date	2010-12
Publishing country	England
Document type	Comment ; Editorial
ZDB-ID	3087-9
ISSN	1468-330X ; 0022-3050
ISSN (online)	1468-330X
ISSN	0022-3050
DOI	10.1136/jnnp.2010.222471
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Article: Falling through the cracks: a literature review to understand the reality of mild stroke survivors.

Tellier, Myriam / Rochette, Annie

Topics in stroke rehabilitation

2009 Volume 16, Issue 6, Page(s) 454–462

Abstract: Purpose: To review the existing literature on mild stroke, its consequences for patients and families, and the effectiveness of rehabilitation services targeting mild stroke.: Method: A systematic search was conducted on Ovid (EMBASE and MEDLINE, ... ...

Abstract	Purpose: To review the existing literature on mild stroke, its consequences for patients and families, and the effectiveness of rehabilitation services targeting mild stroke. Method: A systematic search was conducted on Ovid (EMBASE and MEDLINE, 1950-2008), PubMed, CINAHL, and Cochrane (to 4th quarter 2008). Articles had to be written in French or English. The term "mild stroke" was combined with a variety of key words. Titles, abstracts, and results sections were screened, and the sample had to be composed of not greater-than 50% mild stroke. Two reviewers were involved in the selection process to ensure the research was reproducible and that all the literature was screened properly. Results: Thirteen articles meeting inclusion and exclusion criteria were found. Mild stroke survivors may present impairments that do not interfere with basic activities of daily living but do affect performance of complex tasks. The consequences for families remain unknown. Home interventions were found to help patients maximize their functions and reduce stroke sequelae. Conclusion: The majority of mild stroke survivors are sent home without referral to rehabilitation services although they present deficits that, if not addressed, can lead to deconditioning and impede community reengagement. The impact of mild stroke on families needs to be studied.
MeSH term(s)	Activities of Daily Living ; Affect ; Cognition Disorders/etiology ; Databases, Factual/statistics & numerical data ; Family/psychology ; Home Care Services/statistics & numerical data ; Humans ; Quality of Life ; Stroke/complications ; Stroke/psychology ; Stroke Rehabilitation ; Survivors/psychology
Language	English
Publishing date	2009-11
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	1213112-x
ISSN	1074-9357
ISSN	1074-9357
DOI	10.1310/tsr1606-454
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Article ; Online: Actual and ideal services in acute care and rehabilitation for relatives post-stroke from three perspectives: Relatives, stroke clients and health professionals.

Rochette, Annie / Racine, Eric / Lefebvre, Helene / Bastien, Josee / Tellier, Myriam

Journal of rehabilitation medicine

2014 Volume 46, Issue 1, Page(s) 16–22

Abstract: Objective: To document the gap between actual and desired ideal services for relatives post-stroke from three perspectives: relatives, stroke clients and health professionals.: Methods: A two-phase qualitative design and consisting of in-depth ... ...

Abstract	Objective: To document the gap between actual and desired ideal services for relatives post-stroke from three perspectives: relatives, stroke clients and health professionals. Methods: A two-phase qualitative design and consisting of in-depth interviews (Phase 1) and 3 focus groups (Phase 2). The interview sample consisted of 25 relatives (mean age 53.4 (standard deviation 12.7); women = 21/25) and 16 individuals with a first stroke (mean age = 55.7 (standard deviation 11.2); women = 7/16). The focus group sample size varied from 5 to 7 participants. An interview guide validated by experts was used. Audio content was transcribed verbatim and rigorously analyzed by two team members. Results: Services received by relatives are diversified, and relatives' perceptions range from receiving no services to being satisfied with services received. Even when participants were satisfied, ideal services were still desired: they would have liked to receive services earlier and without having to seek. Four main factors emerged as influencing the amount and quality of services received, including the individual's ability to seek. Conclusions: A gap remains between actual and ideal services for relatives post-stroke. It is crucial to legitimized relatives' role as clients and to systematically assess the patient's social environment in order to provide services in accordance with needs.
MeSH term(s)	Adult ; Aged ; Family ; Female ; Focus Groups ; Health Personnel ; Health Services Needs and Demand/standards ; Humans ; Male ; Middle Aged ; Stroke/therapy ; Stroke Rehabilitation
Language	English
Publishing date	2014-01
Publishing country	Sweden
Document type	Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
ZDB-ID	2039427-5
ISSN	1651-2081 ; 1651-2235 ; 0891-060X ; 1650-1977
ISSN (online)	1651-2081 ; 1651-2235
ISSN	0891-060X ; 1650-1977
DOI	10.2340/16501977-1228
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Article ; Online: Impact of mild stroke on the quality of life of spouses.

Tellier, Myriam / Rochette, Annie / Lefebvre, Hélène

International journal of rehabilitation research. Internationale Zeitschrift fur Rehabilitationsforschung. Revue internationale de recherches de readaptation

2011 Volume 34, Issue 3, Page(s) 209–214

Abstract: Clients with mild stroke may present subtle deficits that have an impact on complex activities and roles. The purpose of this study was to explore the perceived quality of life of spouses, 3 months after the client with stroke was discharged to go home ... ...

Abstract	Clients with mild stroke may present subtle deficits that have an impact on complex activities and roles. The purpose of this study was to explore the perceived quality of life of spouses, 3 months after the client with stroke was discharged to go home from acute care. A qalitative design based on a constructivist paradigm was used. Interviews were conducted with family members of the clients with mild stroke, 3 months after discharge. An interview guide was used and the audio content was transcribed, followed by a content analysis. In this study, eight interviews were conducted (mean age 56.9±9.2 years; men=2/8), and six essential themes emerged from the data. According to the participants, clients with mild stroke present sequelae that interfere with complex tasks (patient), increasing the burden on other family members who have to limit their personal activities (daily living). Sometimes, spouses were reported to act like a parent, which caused tensions in the relationship (conjugal relationship). Anxiety is related to the risk of stroke recurrence (relapse) and some family members present physical symptoms and a lack of energy (health). However, family members do not have access to services despite support from their relatives (services). The results of this exploratory study strongly suggest that even a 'mild' stroke has an impact on the daily lives of spouses and affects their quality of life.
MeSH term(s)	Activities of Daily Living/psychology ; Aged ; Caregivers/psychology ; Cost of Illness ; Disability Evaluation ; Female ; Humans ; Interview, Psychological ; Male ; Middle Aged ; Patient Discharge ; Quality of Life/psychology ; Secondary Prevention ; Social Support ; Spouses/psychology ; Stroke/psychology ; Stroke Rehabilitation
Language	English
Publishing date	2011-09
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	533323-4
ISSN	1473-5660 ; 0342-5282
ISSN (online)	1473-5660
ISSN	0342-5282
DOI	10.1097/MRR.0b013e328343d540
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Article ; Online: Could stroke trigger be prevented by healthy family relationships?

Rochette, Annie / Gaulin, Philippe / Tellier, Myriam

International journal of rehabilitation research. Internationale Zeitschrift fur Rehabilitationsforschung. Revue internationale de recherches de readaptation

2009 Volume 32, Issue 2, Page(s) 173–177

Abstract: Although major stroke risk factors are well documented, little is known about which life circumstances are perceived to be related to the actual triggering of a first stroke. The purpose was to explore self-perceived spontaneously related life ... ...

Abstract	Although major stroke risk factors are well documented, little is known about which life circumstances are perceived to be related to the actual triggering of a first stroke. The purpose was to explore self-perceived spontaneously related life circumstances surrounding the trigger of a first stroke. A qualitative design with a phenomenological orientation was used. Nine individuals with a first stroke and less than 80 years of age were purposely recruited in 2 weeks after the stroke onset. An interview guide developed by experts was used. All interviews were transcribed verbatim and data analysis followed a rigorous process including team validation. All participants had in common a spontaneous reference to a family conflict regarding a specific event they tended to avoid surrounding the trigger of the stroke, which was temporarily resolved after the stroke onset. Essential themes emerging from the data refer to symbols such as a big heart and money issues as well as ambivalent feelings of responsibility, and guilt regarding social roles such as being a spouse or parent. This study provides a deeper understanding of the positive consequences the stroke had in temporarily resolving some family conflicts tainted by a lack of transparency and honesty regarding ambivalent feelings. Further exploration is needed as secondary prevention and health promotion campaigns could specifically target healthy transparent and honest family relationships as a potential protective factor against triggering a stroke, if these results are confirmed in future studies.
MeSH term(s)	Aged ; Family Conflict ; Female ; Health Promotion ; Humans ; Male ; Middle Aged ; Qualitative Research ; Stroke/prevention & control ; Stroke Rehabilitation
Language	English
Publishing date	2009-06
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	533323-4
ISSN	1473-5660 ; 0342-5282
ISSN (online)	1473-5660
ISSN	0342-5282
DOI	10.1097/MRR.0b013e32831e7f54
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Article: THE LESSONIA NIGRESCENS SPECIES COMPLEX (LAMINARIALES, PHAEOPHYCEAE) SHOWS STRICT PARAPATRY AND COMPLETE REPRODUCTIVE ISOLATION IN A SECONDARY CONTACT ZONE(1).

Tellier, Florence / Tapia, Javier / Faugeron, Sylvain / Destombe, Christophe / Valero, Myriam

Journal of phycology

2011 Volume 47, Issue 4, Page(s) 894–903

Abstract: During secondary contact between phylogenetically closely related species (sibling species) having diverged in allopatry, the maintenance of species integrity depends on intrinsic and extrinsic reproductive barriers. In kelps (Phaeophyceae), the ... ...

Abstract	During secondary contact between phylogenetically closely related species (sibling species) having diverged in allopatry, the maintenance of species integrity depends on intrinsic and extrinsic reproductive barriers. In kelps (Phaeophyceae), the observations of hybrids in laboratory conditions suggest that reproductive isolation is incomplete. However, not all interspecific crosses are successful, and very few hybrids have been observed in nature, despite the co-occurrence of many kelp species in sympatry. This suggests that there are reproductive barriers that maintain species integrity. In this study, we characterized the fine genetic structure of a secondary contact zone to clarify the extent of reproductive isolation between two sister species. In Lessonia nigrescens Bory (Laminariales, Phaeophyta) species complex, two cryptic species have been recently found out from gene phylogenies, and-waiting for a formal taxonomic description-we used their geographic distribution to name them (northern and southern species). We studied 12 populations, distributed along 50 km of coastline, and employed two molecular approaches, assigning individuals to phylogenetic species according to a diagnostic mitochondrial marker (351 individuals analyzed) and quantifying interspecific gene flow with four microsatellite markers (248 individuals analyzed). No hybridization or introgression was revealed, indicating complete reproductive isolation in natural conditions. Unexpectedly, our study demonstrated that the two species were strictly segregated in space. This absence of co-occurrence along the contact zone can partially explain the lack of hybridization, raising new interesting questions as to the mechanisms that limit sympatry at small spatial scales.
Language	English
Publishing date	2011-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	281226-5
ISSN	1529-8817 ; 0022-3646
ISSN (online)	1529-8817
ISSN	0022-3646
DOI	10.1111/j.1529-8817.2011.01019.x
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Article ; Online: Ethical issues relating to the inclusion of relatives as clients in the post-stroke rehabilitation process as perceived by patients, relatives and health professionals.

Rochette, Annie / Racine, Eric / Lefebvre, Helene / Lacombe, Jocelyne / Bastien, Josee / Tellier, Myriam

Patient education and counseling

2013 Volume 94, Issue 3, Page(s) 384–389

Abstract: Objective: To document the ethical issues regarding the systematic inclusion of relatives as clients in the post-stroke rehabilitation process.: Methods: A two-phase qualitative design consisting of in-depth interviews with relatives and stroke- ... ...

Abstract	Objective: To document the ethical issues regarding the systematic inclusion of relatives as clients in the post-stroke rehabilitation process. Methods: A two-phase qualitative design consisting of in-depth interviews with relatives and stroke-clients (Phase 1) and three focus groups with relatives, stroke-clients and health professionals (Phase 2). Data was audio recorded. Transcribed interviews and focus groups content were rigorously analyzed by two team members. Results: The interview sample was composed of 25 relatives and of 16 individuals with a first stroke whereas the three focus group sample size varied from 5 to 7 participants. Four main themes emerged: (1) overemphasis of caregiving role with an unclear legitimacy of relative to also be a client; (2) communication as a key issue to foster respect and a family-centered approach; (3) availability and attitudes of health professionals as a facilitator or a barrier to a family-centered approach; and (4) constant presence of relatives as a protective factor or creating a perverse effect. Conclusion/practice implications: The needs of relatives are well known. The next step is to legitimize their right to receive services and to acknowledge the combined clinical and ethical value of including them post-stroke. Interdisciplinary health care approaches and communication skills should be addressed.
MeSH term(s)	Adult ; Aged ; Attitude of Health Personnel ; Canada ; Caregivers/ethics ; Caregivers/psychology ; Family/psychology ; Female ; Humans ; Interviews as Topic ; Male ; Middle Aged ; Patients/psychology ; Perception ; Professional-Family Relations/ethics ; Professional-Patient Relations ; Qualitative Research ; Rehabilitation/ethics ; Social Support ; Stroke Rehabilitation ; Urban Population
Language	English
Publishing date	2013-11-05
Publishing country	Ireland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	605590-4
ISSN	1873-5134 ; 0738-3991
ISSN (online)	1873-5134
ISSN	0738-3991
DOI	10.1016/j.pec.2013.10.028
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Article: THE LESSONIA NIGRESCENS SPECIES COMPLEX (LAMINARIALES, PHAEOPHYCEAE) SHOWS STRICT PARAPATRY AND COMPLETE REPRODUCTIVE ISOLATION IN A SECONDARY CONTACT ZONE

Tellier, Florence / Tapia, Javier / Faugeron, Sylvain / Destombe, Christophe / Valero, Myriam

Journal of phycology. 2011 Aug., v. 47, no. 4

2011

Abstract	During secondary contact between phylogenetically closely related species (sibling species) having diverged in allopatry, the maintenance of species integrity depends on intrinsic and extrinsic reproductive barriers. In kelps (Phaeophyceae), the observations of hybrids in laboratory conditions suggest that reproductive isolation is incomplete. However, not all interspecific crosses are successful, and very few hybrids have been observed in nature, despite the co-occurrence of many kelp species in sympatry. This suggests that there are reproductive barriers that maintain species integrity. In this study, we characterized the fine genetic structure of a secondary contact zone to clarify the extent of reproductive isolation between two sister species. In Lessonia nigrescens Bory (Laminariales, Phaeophyta) species complex, two cryptic species have been recently found out from gene phylogenies, and--waiting for a formal taxonomic description--we used their geographic distribution to name them (northern and southern species). We studied 12 populations, distributed along 50 km of coastline, and employed two molecular approaches, assigning individuals to phylogenetic species according to a diagnostic mitochondrial marker (351 individuals analyzed) and quantifying interspecific gene flow with four microsatellite markers (248 individuals analyzed). No hybridization or introgression was revealed, indicating complete reproductive isolation in natural conditions. Unexpectedly, our study demonstrated that the two species were strictly segregated in space. This absence of co-occurrence along the contact zone can partially explain the lack of hybridization, raising new interesting questions as to the mechanisms that limit sympatry at small spatial scales.
Keywords	Laminariales ; allopatry ; coasts ; gene flow ; genes ; geographical distribution ; hybrids ; introgression ; macroalgae ; microsatellite repeats ; reproductive isolation ; secondary contact ; sibling species ; sympatry
Language	English
Dates of publication	2011-08
Size	p. 894-903.
Publishing place	Blackwell Publishing Ltd
Document type	Article
ZDB-ID	281226-5
ISSN	0022-3646
ISSN	0022-3646
DOI	10.1111/j.1529-8817.2011.01019.x
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Article ; Online: Temperature effects on gametophyte life-history traits and geographic distribution of two cryptic kelp species.

Oppliger, L Valeria / Correa, Juan A / Engelen, Aschwin H / Tellier, Florence / Vieira, Vasco / Faugeron, Sylvain / Valero, Myriam / Gomez, Gonzalo / Destombe, Christophe

PloS one

2012 Volume 7, Issue 6, Page(s) e39289

Abstract: A major determinant of the geographic distribution of a species is expected to be its physiological response to changing abiotic variables over its range. The range of a species often corresponds to the geographic extent of temperature regimes the ... ...

Abstract	A major determinant of the geographic distribution of a species is expected to be its physiological response to changing abiotic variables over its range. The range of a species often corresponds to the geographic extent of temperature regimes the organism can physiologically tolerate. Many species have very distinct life history stages that may exhibit different responses to environmental factors. In this study we emphasized the critical role of the haploid microscopic stage (gametophyte) of the life cycle to explain the difference of edge distribution of two related kelp species. Lessonia nigrescens was recently identified as two cryptic species occurring in parapatry along the Chilean coast: one located north and the other south of a biogeographic boundary at latitude 29-30°S. Six life history traits from microscopic stages were identified and estimated under five treatments of temperature in eight locations distributed along the Chilean coast in order to (1) estimate the role of temperature in the present distribution of the two cryptic L. nigrescens species, (2) compare marginal populations to central populations of the two cryptic species. In addition, we created a periodic matrix model to estimate the population growth rate (λ) at the five temperature treatments. Differential tolerance to temperature was demonstrated between the two species, with the gametophytes of the Northern species being more tolerant to higher temperatures than gametophytes from the south. Second, the two species exhibited different life history strategies with a shorter haploid phase in the Northern species contrasted with considerable vegetative growth in the Southern species haploid stage. These results provide strong ecological evidence for the differentiation process of the two cryptic species and show local adaptation of the life cycle at the range limits of the distribution. Ecological and evolutionary implications of these findings are discussed.
MeSH term(s)	Analysis of Variance ; Chile ; Ecosystem ; Geography ; Germ Cells, Plant/metabolism ; Kelp/genetics ; Kelp/growth & development ; Quantitative Trait, Heritable ; Temperature
Language	English
Publishing date	2012-06-18
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0039289
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Article ; Online: Phylogeographic analyses of the 30 degrees S south-east Pacific biogeographic transition zone establish the occurrence of a sharp genetic discontinuity in the kelp Lessonia nigrescens: vicariance or parapatry?

Tellier, Florence / Meynard, Andrés P / Correa, Juan A / Faugeron, Sylvain / Valero, Myriam

Molecular phylogenetics and evolution

2009 Volume 53, Issue 3, Page(s) 679–693

Abstract: Phylogeographic studies are lacking in the Southern Hemisphere, and in particular in the south-eastern Pacific. To infer the possible scenario for the debated biogeographic transition zone located at 30-33 degrees S along the Chilean coast, we ... ...

Abstract	Phylogeographic studies are lacking in the Southern Hemisphere, and in particular in the south-eastern Pacific. To infer the possible scenario for the debated biogeographic transition zone located at 30-33 degrees S along the Chilean coast, we investigated whether there is a concordance between the phylogeographic pattern and the biogeographic transition in the intertidal kelp Lessonia nigrescens whose distribution is continuous across this transition zone. Using a combination of four makers located in the three genomic compartments (chloroplast, mitochondria and nucleus), we showed the presence of two main divergent lineages, possibly cryptic species. There was an exact match of the phylogeographic break with the 30 degrees S biogeographic transition zone, suggesting a common origin. The combined information given by the multilocus approach and by the population analysis suggested the occurrence of a budding speciation, with a northward range expansion.
MeSH term(s)	Base Sequence ; Cell Nucleus/genetics ; DNA, Algal/genetics ; DNA, Chloroplast/genetics ; DNA, Mitochondrial/genetics ; Evolution, Molecular ; Genetic Speciation ; Genetics, Population ; Geography ; Kelp/classification ; Kelp/genetics ; Molecular Sequence Data ; Pacific Ocean ; Phylogeny ; Polymorphism, Single-Stranded Conformational ; Sequence Alignment ; Sequence Analysis, DNA
Chemical Substances	DNA, Algal ; DNA, Chloroplast ; DNA, Mitochondrial
Language	English
Publishing date	2009-07-30
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	33610-5
ISSN	1095-9513 ; 1055-7903
ISSN (online)	1095-9513
ISSN	1055-7903
DOI	10.1016/j.ympev.2009.07.030
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