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  1. Article ; Online: Falling through the cracks: the impact of COVID-19 on postnatal care in primary care.

    MacGregor, Rebecca / Hillman, Sarah / Bick, Debra

    The British journal of general practice : the journal of the Royal College of General Practitioners

    2020  Volume 70, Issue 701, Page(s) 578–579

    MeSH term(s) COVID-19/epidemiology ; COVID-19/prevention & control ; Communicable Disease Control/methods ; Female ; Health Services Needs and Demand ; Humans ; Infant, Newborn ; Male ; Organizational Innovation ; Physical Distancing ; Postnatal Care/methods ; Postnatal Care/organization & administration ; Postnatal Care/standards ; Postnatal Care/trends ; Primary Health Care/methods ; Primary Health Care/organization & administration ; SARS-CoV-2 ; State Medicine/standards ; Telemedicine ; United Kingdom ; Women's Health/standards
    Keywords covid19
    Language English
    Publishing date 2020-11-26
    Publishing country England
    Document type Editorial
    ZDB-ID 1043148-2
    ISSN 1478-5242 ; 0035-8797 ; 0960-1643
    ISSN (online) 1478-5242
    ISSN 0035-8797 ; 0960-1643
    DOI 10.3399/bjgp20X713573
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  2. Article ; Online: Erratum: "Causal Contributions of the Domain-General (Multiple Demand) and the Language-Selective Brain Networks to Perceptual and Semantic Challenges in Speech Comprehension".

    MacGregor, Lucy J / Gilbert, Rebecca A / Balewski, Zuzanna / Mitchell, Daniel J / Erzinçlioğlu, Sharon W / Rodd, Jennifer M / Duncan, John / Fedorenko, Evelina / Davis, Matthew H

    Neurobiology of language (Cambridge, Mass.)

    2023  Volume 4, Issue 1, Page(s) i–ii

    Abstract: This corrects the article DOI: 10.1162/nol_a_00081.]. ...

    Abstract [This corrects the article DOI: 10.1162/nol_a_00081.].
    Language English
    Publishing date 2023-02-17
    Publishing country United States
    Document type Published Erratum
    ISSN 2641-4368
    ISSN (online) 2641-4368
    DOI 10.1162/nol_x_00103
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  4. Article ; Online: Implementation strategies to improve posttraumatic stress disorder care in rural veterans.

    Bernardy, Nancy C / Cuccurullo, Lisa-Ann J / Montano, Macgregor / Bowen, Michelle / Breen, Kristen / Matteo, Rebecca / Cole, Bernard

    The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association

    2023  

    Abstract: Purpose: Prior research has noted treatment inequalities in the care of rural veterans with posttraumatic stress disorder (PTSD). This project sought to increase the delivery, or reach, of recommended PTSD treatments in 2 rural health care systems of ... ...

    Abstract Purpose: Prior research has noted treatment inequalities in the care of rural veterans with posttraumatic stress disorder (PTSD). This project sought to increase the delivery, or reach, of recommended PTSD treatments in 2 rural health care systems of the Department of Veterans Affairs (VA) using implementation facilitation.
    Methods: The quality improvement project involved 6 months of facilitation to 2 low-reach PTSD clinics within 2 VA health care systems. The clinics were matched to a control clinic at another regional system similar in reach, rurality, and patient volume. We compared the delivery of evidence-based psychotherapies (EBPs) for PTSD at 3 timepoints: baseline, 6 months, and 1 year using difference-in-difference effect estimation. Facilitators and barriers of EBP reach were identified through interviews with clinic staff and informed specific implementation plans. We also measured reductions in benzodiazepine prescriptions and polypharmacy to determine the impact of an academic detailing intervention aimed at improving PTSD prescribing practices at the 2 sites.
    Findings: EBP reach at 6 months more than doubled in the 2 PTSD clinics that received facilitation, while our control clinic experienced a decrease in EBP reach (DID = 24.6; SE = 6.71%). Both intervention clinics identified similar administrative barriers to the delivery of EBPs, offering useful information for improvement at other rural clinics. The use of academic detailing as part of our facilitation intervention further appears to have positively impacted care.
    Conclusions: In this preliminary work, facilitation is a promising strategy for increasing the delivery of PTSD EBPs to veterans seen in under-resourced rural VA clinics.
    Language English
    Publishing date 2023-08-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 639160-6
    ISSN 1748-0361 ; 0890-765X
    ISSN (online) 1748-0361
    ISSN 0890-765X
    DOI 10.1111/jrh.12790
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  5. Article ; Online: The genomic epidemiology of Escherichia albertii infecting humans and birds in Great Britain.

    Bengtsson, Rebecca J / Baker, Kate S / Cunningham, Andrew A / Greig, David R / John, Shinto K / Macgregor, Shaheed K / Seilern-Moy, Katharina / Spiro, Simon / Chong, Charlotte C / De Silva, P Malaka / Jenkins, Claire / Lawson, Becki

    Nature communications

    2023  Volume 14, Issue 1, Page(s) 1707

    Abstract: Escherichia albertii is a recently identified gastrointestinal bacterial pathogen of humans and animals which is typically misidentified as pathotypes of diarrhoeagenic Escherichia coli or Shigella species and is generally only detected during genomic ... ...

    Abstract Escherichia albertii is a recently identified gastrointestinal bacterial pathogen of humans and animals which is typically misidentified as pathotypes of diarrhoeagenic Escherichia coli or Shigella species and is generally only detected during genomic surveillance of other Enterobacteriaceae. The incidence of E. albertii is likely underestimated, and its epidemiology and clinical relevance are poorly characterised. Here, we whole genome sequenced E. albertii isolates from humans (n = 83) and birds (n = 79) isolated in Great Britain between 2000 and 2021 and analysed these alongside a broader public dataset (n = 475) to address these gaps. We found human and avian isolates typically (90%; 148/164) belonged to host-associated monophyletic groups with distinct virulence and antimicrobial resistance profiles. Overlaid patient epidemiological data suggested that human infection was likely related to travel and possibly foodborne transmission. The Shiga toxin encoding stx2f gene was associated with clinical disease (OR = 10.27, 95% CI = 2.98-35.45 p = 0.0002) in finches. Our results suggest that improved future surveillance will further elucidate disease ecology and public and animal health risks associated with E. albertii.
    MeSH term(s) Animals ; Humans ; United Kingdom/epidemiology ; Enterobacteriaceae Infections/epidemiology ; Enterobacteriaceae Infections/veterinary ; Enterobacteriaceae Infections/microbiology ; Birds ; Escherichia coli ; Genomics ; Escherichia coli Infections/epidemiology ; Escherichia coli Infections/veterinary
    Language English
    Publishing date 2023-03-27
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-023-37312-3
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  6. Article ; Online: Sex differences in the effects of prematurity and/or low birthweight on neurodevelopmental outcomes: systematic review and meta-analyses.

    Christians, Julian K / Ahmadzadeh-Seddeighi, Saboura / Bilal, Alishba / Bogdanovic, Anastasia / Ho, Rebecca / Leung, Estee V / MacGregor, Megan A / Nadasdy, Nolan M / Principe, Gabriella M

    Biology of sex differences

    2023  Volume 14, Issue 1, Page(s) 47

    Abstract: Background: Premature birth and/or low birthweight have long-lasting effects on cognition. The purpose of the present systematic review is to examine whether the effects of prematurity and/or low birth weight on neurodevelopmental outcomes differ ... ...

    Abstract Background: Premature birth and/or low birthweight have long-lasting effects on cognition. The purpose of the present systematic review is to examine whether the effects of prematurity and/or low birth weight on neurodevelopmental outcomes differ between males and females.
    Methods: Web of Science, Scopus, and Ovid MEDLINE were searched for studies of humans born premature and/or of low birthweight, where neurodevelopmental phenotypes were measured at 1 year of age or older. Studies must have reported outcomes in such a way that it was possible to assess whether effects were greater in one sex than the other. Risk of bias was assessed using both the Newcastle-Ottawa scale and the National Institutes of Health Quality assessment tool for observational cohort and cross-sectional studies.
    Results: Seventy-five studies were included for descriptive synthesis, although only 24 presented data in a way that could be extracted for meta-analyses. Meta-analyses found that severe and moderate prematurity/low birthweight impaired cognitive function, and severe prematurity/low birthweight also increased internalizing problem scores. Moderate, but not severe, prematurity/low birthweight significantly increased externalizing problem scores. In no case did effects of prematurity/low birthweight differ between males and females. Heterogeneity among studies was generally high and significant, although age at assessment was not a significant moderator of effect. Descriptive synthesis did not identify an obvious excess or deficiency of male-biased or female-biased effects for any trait category. Individual study quality was generally good, and we found no evidence of publication bias.
    Conclusions: We found no evidence that the sexes differ in their susceptibility to the effects of severe or moderate prematurity/low birthweight on cognitive function, internalizing traits or externalizing traits. Result heterogeneity tended to be high, but this reflects that one sex is not consistently more affected than the other. Frequently stated generalizations that one sex is more susceptible to prenatal adversity should be re-evaluated.
    MeSH term(s) United States ; Pregnancy ; Female ; Male ; Humans ; Infant, Newborn ; Premature Birth ; Sex Characteristics ; Birth Weight ; Cross-Sectional Studies ; Infant, Low Birth Weight
    Language English
    Publishing date 2023-07-11
    Publishing country England
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2587352-0
    ISSN 2042-6410 ; 2042-6410
    ISSN (online) 2042-6410
    ISSN 2042-6410
    DOI 10.1186/s13293-023-00532-9
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  7. Article ; Online: Causal Contributions of the Domain-General (Multiple Demand) and the Language-Selective Brain Networks to Perceptual and Semantic Challenges in Speech Comprehension.

    MacGregor, Lucy J / Gilbert, Rebecca A / Balewski, Zuzanna / Mitchell, Daniel J / Erzinçlioğlu, Sharon W / Rodd, Jennifer M / Duncan, John / Fedorenko, Evelina / Davis, Matthew H

    Neurobiology of language (Cambridge, Mass.)

    2022  Volume 3, Issue 4, Page(s) 665–698

    Abstract: Listening to spoken language engages domain-general multiple demand (MD; frontoparietal) regions of the human brain, in addition to domain-selective (frontotemporal) language regions, particularly when comprehension is challenging. However, there is ... ...

    Abstract Listening to spoken language engages domain-general multiple demand (MD; frontoparietal) regions of the human brain, in addition to domain-selective (frontotemporal) language regions, particularly when comprehension is challenging. However, there is limited evidence that the MD network makes a functional contribution to core aspects of understanding language. In a behavioural study of volunteers (
    Language English
    Publishing date 2022-12-16
    Publishing country United States
    Document type Journal Article
    ISSN 2641-4368
    ISSN (online) 2641-4368
    DOI 10.1162/nol_a_00081
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  8. Article ; Online: Sex differences in the effects of prematurity and/or low birthweight on neurodevelopmental outcomes

    Julian K. Christians / Saboura Ahmadzadeh-Seddeighi / Alishba Bilal / Anastasia Bogdanovic / Rebecca Ho / Estee V. Leung / Megan A. MacGregor / Nolan M. Nadasdy / Gabriella M. Principe

    Biology of Sex Differences, Vol 14, Iss 1, Pp 1-

    systematic review and meta-analyses

    2023  Volume 19

    Abstract: Abstract Background Premature birth and/or low birthweight have long-lasting effects on cognition. The purpose of the present systematic review is to examine whether the effects of prematurity and/or low birth weight on neurodevelopmental outcomes differ ...

    Abstract Abstract Background Premature birth and/or low birthweight have long-lasting effects on cognition. The purpose of the present systematic review is to examine whether the effects of prematurity and/or low birth weight on neurodevelopmental outcomes differ between males and females. Methods Web of Science, Scopus, and Ovid MEDLINE were searched for studies of humans born premature and/or of low birthweight, where neurodevelopmental phenotypes were measured at 1 year of age or older. Studies must have reported outcomes in such a way that it was possible to assess whether effects were greater in one sex than the other. Risk of bias was assessed using both the Newcastle–Ottawa scale and the National Institutes of Health Quality assessment tool for observational cohort and cross-sectional studies. Results Seventy-five studies were included for descriptive synthesis, although only 24 presented data in a way that could be extracted for meta-analyses. Meta-analyses found that severe and moderate prematurity/low birthweight impaired cognitive function, and severe prematurity/low birthweight also increased internalizing problem scores. Moderate, but not severe, prematurity/low birthweight significantly increased externalizing problem scores. In no case did effects of prematurity/low birthweight differ between males and females. Heterogeneity among studies was generally high and significant, although age at assessment was not a significant moderator of effect. Descriptive synthesis did not identify an obvious excess or deficiency of male-biased or female-biased effects for any trait category. Individual study quality was generally good, and we found no evidence of publication bias. Conclusions We found no evidence that the sexes differ in their susceptibility to the effects of severe or moderate prematurity/low birthweight on cognitive function, internalizing traits or externalizing traits. Result heterogeneity tended to be high, but this reflects that one sex is not consistently more affected than the other. Frequently ...
    Keywords Systematic review ; Prematurity ; Birthweight ; Sex differences ; Gender ; Cognitive function ; Medicine ; R ; Physiology ; QP1-981
    Subject code 150
    Language English
    Publishing date 2023-07-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: The genomic epidemiology of Escherichia albertii infecting humans and birds in Great Britain

    Rebecca J. Bengtsson / Kate S. Baker / Andrew A. Cunningham / David R. Greig / Shinto K. John / Shaheed K. Macgregor / Katharina Seilern-Moy / Simon Spiro / Charlotte C. Chong / P Malaka De Silva / Claire Jenkins / Becki Lawson

    Nature Communications, Vol 14, Iss 1, Pp 1-

    2023  Volume 13

    Abstract: Escherichia albertii is an emerging gastrointestinal pathogen that causes disease in humans and animals, notably birds. In this genomic epidemiology study, the authors investigate characteristics of isolates sampled from humans and birds in Great Britain ...

    Abstract Escherichia albertii is an emerging gastrointestinal pathogen that causes disease in humans and animals, notably birds. In this genomic epidemiology study, the authors investigate characteristics of isolates sampled from humans and birds in Great Britain and find that they tend to cluster separately.
    Keywords Science ; Q
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Unlocking the potential of historical abundance datasets to study biomass change in flying insects.

    Kinsella, Rebecca S / Thomas, Chris D / Crawford, Terry J / Hill, Jane K / Mayhew, Peter J / Macgregor, Callum J

    Ecology and evolution

    2020  Volume 10, Issue 15, Page(s) 8394–8404

    Abstract: Trends in insect abundance are well established in some datasets, but far less is known about how abundance measures translate into biomass trends. Moths (Lepidoptera) provide particularly good opportunities to study trends and drivers of biomass change ... ...

    Abstract Trends in insect abundance are well established in some datasets, but far less is known about how abundance measures translate into biomass trends. Moths (Lepidoptera) provide particularly good opportunities to study trends and drivers of biomass change at large spatial and temporal scales, given the existence of long-term abundance datasets. However, data on the body masses of moths are required for these analyses, but such data do not currently exist.To address this data gap, we collected empirical data in 2018 on the forewing length and dry mass of field-sampled moths, and used these to train and test a statistical model that predicts the body mass of moth species from their forewing lengths (with refined parameters for Crambidae, Erebidae, Geometridae and Noctuidae).Modeled biomass was positively correlated, with high explanatory power, with measured biomass of moth species (
    Language English
    Publishing date 2020-07-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2635675-2
    ISSN 2045-7758
    ISSN 2045-7758
    DOI 10.1002/ece3.6546
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