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  1. Article ; Online: A commentary on "impact of lymphadenectomy extent on immunotherapy efficacy in postresectional recurred non-small cell lung cancer: a multi-institutional retrospective cohort study".

    Zhang, Chengcheng / Qin, Jingru / Zhao, Xiaoxue / Yang, Lu / Wang, Zhongqi

    International journal of surgery (London, England)

    2024  

    Language English
    Publishing date 2024-03-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2212038-5
    ISSN 1743-9159 ; 1743-9191
    ISSN (online) 1743-9159
    ISSN 1743-9191
    DOI 10.1097/JS9.0000000000001347
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  2. Article ; Online: China's young researchers offered new opportunities.

    Zhang, Jingru / Lu, Kexin / Wei, Wendong

    Nature

    2022  Volume 609, Issue 7927, Page(s) 467

    MeSH term(s) Age Factors ; China ; Research Personnel
    Language English
    Publishing date 2022-09-13
    Publishing country England
    Document type Letter
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/d41586-022-02898-z
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  3. Article ; Online: Association between hyperglycemia during pregnancy and offspring's refractive error: A focused review.

    Guo, Yufan / Lu, Jingru / Zhu, Linlin / Hao, Xuemei / Huang, Kun

    European journal of ophthalmology

    2024  , Page(s) 11206721241238389

    Abstract: This review article explores the relationship between hyperglycemia during pregnancy and the visual development of offspring, specifically focusing on refractive error. The authors conducted a comprehensive search for relevant articles in various ... ...

    Abstract This review article explores the relationship between hyperglycemia during pregnancy and the visual development of offspring, specifically focusing on refractive error. The authors conducted a comprehensive search for relevant articles in various databases and assessed the methodological quality of the included studies. The findings consistently indicate that hyperglycemia during pregnancy can have a detrimental impact on the structural and functional aspects of visual development in offspring. The intrauterine hyperglycemic environment appears to negatively affect the retina and lens, leading to refractive errors. In conclusion, there is likely an association between hyperglycemia during pregnancy and the development of refractive errors in offspring.
    Language English
    Publishing date 2024-03-24
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1089461-5
    ISSN 1724-6016 ; 1120-6721
    ISSN (online) 1724-6016
    ISSN 1120-6721
    DOI 10.1177/11206721241238389
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  4. Article ; Online: Synergistic Effect of Genetic Predisposition and Lifestyle for Coronary Heart Disease.

    Lu, Linyao / Suo, Chen / Wang, Jingru / Zhao, Renjia / Zhu, Dongliang / Zhang, Tiejun / Chen, Xingdong / Jiang, Yanfeng

    European journal of preventive cardiology

    2024  

    Language English
    Publishing date 2024-02-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 2626011-6
    ISSN 2047-4881 ; 2047-4873
    ISSN (online) 2047-4881
    ISSN 2047-4873
    DOI 10.1093/eurjpc/zwae077
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  5. Article ; Online: Correlation between the MNCD classification-based staging of Parkinson's disease and quality of life: a cross-sectional study.

    He, Guixiang / Ren, Jingru / Shi, Haicun / Liu, Weiguo / Lu, Ming

    Journal of neural transmission (Vienna, Austria : 1996)

    2024  Volume 131, Issue 4, Page(s) 315–322

    Abstract: Parkinson's disease (PD) is a highly heterogeneous neurodegenerative disorder with varying clinical subtypes. Recently, a novel classification called MNCD (Motor/Non-motor/Cognition/Dependency) has been proposed, which can also include staging based on ... ...

    Abstract Parkinson's disease (PD) is a highly heterogeneous neurodegenerative disorder with varying clinical subtypes. Recently, a novel classification called MNCD (Motor/Non-motor/Cognition/Dependency) has been proposed, which can also include staging based on disease severity. We aim to investigate which staging, the MNCD classification and staging or Hoehn and Yahr (H&Y) staging, exhibits a stronger correlation with the 39-item Parkinson's Disease Questionnaire (PDQ-39). In a cross-sectional study conducted at our single center, 357 PD patients were recruited. Data encompassed scores from various assessments such as the Movement Disorder Society of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Parts I, II, III and IV, Montreal Cognitive Assessment (MoCA), PDQ-39, and the H&Y scale. The mean age of these patients was 66.4 ± 9.1 years old, and the majority (54.6%) were male. MNCD stages: stage 1 (N = 3, 0.8%), stage 2 (N = 62, 17.4%), stage 3 (N = 187, 52.4%), stage 4 (N = 86, 24.1%), and stage 5 (N = 19, 5.3%). The top 5 most frequent PD-related clinical symptoms were sleep disturbances (89.6%), fatigue (69.7%), mild cognitive impairment (68.9%), constipation (65.8%), and postural instability (65.5%). The PDQ-39 demonstrated a positive correlation with both MNCD staging and H&Y staging. Moreover, the MNCD staging exhibited a stronger correlation with PDQ-39 compared to H&Y staging. The correlation between the MNCD classification and staging with the quality of life in PD patients is more statistically significant compared to the H&Y staging.
    MeSH term(s) Humans ; Male ; Female ; Middle Aged ; Aged ; Parkinson Disease/diagnosis ; Quality of Life/psychology ; Cross-Sectional Studies ; Severity of Illness Index ; Fatigue
    Language English
    Publishing date 2024-03-28
    Publishing country Austria
    Document type Journal Article
    ZDB-ID 184163-4
    ISSN 1435-1463 ; 0300-9564
    ISSN (online) 1435-1463
    ISSN 0300-9564
    DOI 10.1007/s00702-024-02756-4
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  6. Article: A broadly applicable quantitative relative reactivity model for nucleophilic aromatic substitution (S

    Lu, Jingru / Paci, Irina / Leitch, David C

    Chemical science

    2022  Volume 13, Issue 43, Page(s) 12681–12695

    Abstract: We report a multivariate linear regression model able to make accurate predictions for the relative rate and regioselectivity of nucleophilic aromatic substitution ( ... ...

    Abstract We report a multivariate linear regression model able to make accurate predictions for the relative rate and regioselectivity of nucleophilic aromatic substitution (S
    Language English
    Publishing date 2022-10-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2559110-1
    ISSN 2041-6539 ; 2041-6520
    ISSN (online) 2041-6539
    ISSN 2041-6520
    DOI 10.1039/d2sc04041g
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  7. Article ; Online: Are there bidirectional associations between maternal thyroid function and glucose metabolism in singleton live births? A birth cohort study.

    Lu, Jingru / Zhu, Linlin / Guo, Yufan / Hao, Xuemei / Yan, Shuangqin / Tao, Fangbiao / Huang, Kun

    Diabetes research and clinical practice

    2024  Volume 209, Page(s) 111569

    Abstract: 1) Aims: To examine the associations between maternal thyroid function and glucose metabolism during pregnancy. (2) Methods: This study was based on Ma' anshan Birth Cohort in China. Totally 2375 pregnant women were included in data analysis. Maternal ... ...

    Abstract (1) Aims: To examine the associations between maternal thyroid function and glucose metabolism during pregnancy. (2) Methods: This study was based on Ma' anshan Birth Cohort in China. Totally 2375 pregnant women were included in data analysis. Maternal thyroid-stimulating hormone (TSH), free thyroxine (FT
    MeSH term(s) Pregnancy ; Female ; Humans ; Thyroid Gland ; Cohort Studies ; Thyroxine ; Retrospective Studies ; Live Birth ; Thyrotropin ; Glucose
    Chemical Substances Thyroxine (Q51BO43MG4) ; Thyrotropin (9002-71-5) ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2024-02-08
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 632523-3
    ISSN 1872-8227 ; 0168-8227
    ISSN (online) 1872-8227
    ISSN 0168-8227
    DOI 10.1016/j.diabres.2024.111569
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  8. Article ; Online: Long Sleep Duration Increases the Risk of All-Cause Mortality Among Community-Dwelling Older Adults With Frailty: Evidence From NHANES 2009-2014.

    Chen, Mingzhuang / Lu, Chao / Zha, Jingru

    Journal of applied gerontology : the official journal of the Southern Gerontological Society

    2022  Volume 42, Issue 5, Page(s) 1078–1088

    Abstract: ... ...

    Abstract Objectives
    MeSH term(s) Aged ; Humans ; Frailty ; Frail Elderly ; Nutrition Surveys ; Independent Living ; Sleep Duration ; Prospective Studies ; Sleep
    Language English
    Publishing date 2022-12-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 155897-3
    ISSN 1552-4523 ; 0733-4648
    ISSN (online) 1552-4523
    ISSN 0733-4648
    DOI 10.1177/07334648221147917
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  9. Article ; Online: Rectify representation bias in vision-language models for long-tailed recognition.

    Li, Bo / Yao, Yongqiang / Tan, Jingru / Gong, Ruihao / Lu, Jianwei / Luo, Ye

    Neural networks : the official journal of the International Neural Network Society

    2024  Volume 172, Page(s) 106134

    Abstract: Natural data typically exhibits a long-tailed distribution, presenting great challenges for recognition tasks. Due to the extreme scarcity of training instances, tail classes often show inferior performance. In this paper, we investigate the problem ... ...

    Abstract Natural data typically exhibits a long-tailed distribution, presenting great challenges for recognition tasks. Due to the extreme scarcity of training instances, tail classes often show inferior performance. In this paper, we investigate the problem within the trendy visual-language (VL) framework and find that the performance bottleneck mainly arises from the recognition confusion between tail classes and their highly correlated head classes. Building upon this observation, unlike previous research primarily emphasizing class frequency in addressing long-tailed issues, we take a novel perspective by incorporating a crucial additional factor namely class correlation. Specifically, we model the representation learning procedure for each sample as two parts, i.e., a special part that learns the unique properties of its own class and a common part that learns shared characteristics among classes. By analysis, we discover that the learning process of common representation is easily biased toward head classes. Because of the bias, the network may lean towards the biased common representation as classification criteria, rather than prioritizing the crucial information encapsulated within the specific representation, ultimately leading to recognition confusion. To solve the problem, based on the VL framework, we introduce the rectification contrastive term (ReCT) to rectify the representation bias, according to semantic hints and training status. Extensive experiments on three widely-used long-tailed datasets demonstrate the effectiveness of ReCT. On iNaturalist2018, it achieves an overall accuracy of 75.4%, surpassing the baseline by 3.6 points in a ResNet-50 visual backbone.
    MeSH term(s) Language ; Semantics ; Bias ; Learning ; Recognition, Psychology
    Language English
    Publishing date 2024-01-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 740542-x
    ISSN 1879-2782 ; 0893-6080
    ISSN (online) 1879-2782
    ISSN 0893-6080
    DOI 10.1016/j.neunet.2024.106134
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  10. Article ; Online: Association of gestational weight gain rate in pregnant women with children's cognitive and behavioral development: A birth cohort study.

    Hao, Xuemei / Zhu, Linlin / Guo, Yufan / Lu, Jingru / Yan, Shuangqin / Tao, Fangbiao / Huang, Kun

    Journal of affective disorders

    2024  Volume 350, Page(s) 792–800

    Abstract: Background: The evidences on the relationship between gestational weight gain rate (GWGR) and children's cognitive and behavioral development have been limited.: Methods: A total of 3273 singleton live birth mother-child pairs from the Ma'anshan ... ...

    Abstract Background: The evidences on the relationship between gestational weight gain rate (GWGR) and children's cognitive and behavioral development have been limited.
    Methods: A total of 3273 singleton live birth mother-child pairs from the Ma'anshan Birth Cohort in China were included in the study. Maternal GWGR was calculated based on the weights measured at multiple antenatal checkups. Children's cognitive and behavioral development were assessed by Chinese version of Wechsler Preschool and Primary Scale of Intelligence-Fourth Edition and Achenbach Child Behavior Checklist 1.5-5. Then generalized linear models were performed for analyses.
    Results: In the field of children's cognitive development, excessive GWGR in the second trimester was associated with increased visual space index (VSI), fluid reasoning index (FRI) and full scale intelligence quotient (FSIQ) scores, while excessive GWGR in the third trimester was associated with decreased VSI, working memory index (WMI) and FSIQ scores. In the field of children's behavioral development, excessive GWGR in the second trimester was associated with decreased aggressive behaviors and externalizing problems scores.
    Limitations: Children's behavioral development was assessed by main caregivers and might cause a certain degree of bias. There might be other potential confounders that we did not take into account.
    Conclusions: A high GWGR in the second trimester might be beneficial for children's cognitive and behavioral development, while a high GWGR in the third trimester might be harmful.
    MeSH term(s) Child, Preschool ; Female ; Humans ; Pregnancy ; Cohort Studies ; Pregnant Women ; Gestational Weight Gain ; Pregnancy Trimester, Third ; Cognition
    Language English
    Publishing date 2024-01-19
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 135449-8
    ISSN 1573-2517 ; 0165-0327
    ISSN (online) 1573-2517
    ISSN 0165-0327
    DOI 10.1016/j.jad.2024.01.154
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