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Article ; Online: Neonatologists and non-vigorous newborns with meconium-stained amniotic fluid (MSAF) in the delivery room: time for hands off? : Comment on: Kumar A, Kumar P, Basu S. "Endotracheal Suctioning for Prevention of Meconium Aspiration Syndrome: A Randomized Controlled Trial." European Journal of Pediatrics 2019.

Lista, Gianluca

2019 Volume 178, Issue 12, Page(s) 1823–1824

MeSH term(s)	Amniotic Fluid ; Child ; Delivery Rooms ; Humans ; Infant, Newborn ; Meconium ; Meconium Aspiration Syndrome ; Neonatologists ; Pediatrics ; Pregnancy
Language	English
Publishing date	2019-10-30
Publishing country	Germany
Document type	Editorial ; Comment
ZDB-ID	194196-3
ISSN	1432-1076 ; 0340-6199 ; 0943-9676
ISSN (online)	1432-1076
ISSN	0340-6199 ; 0943-9676
DOI	10.1007/s00431-019-03501-w
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Article ; Online: Clinical features of neonatal COVID-19.

Galderisi, Alfonso / Lista, Gianluca / Cavigioli, Francesco / Trevisanuto, Daniele

Seminars in fetal & neonatal medicine

2023 Volume 28, Issue 2, Page(s) 101430

Abstract: The COVID-19 (SARS-Cov-2) pandemic has put a strain on healthcare systems around the world from December 2019 in China, and then rapidly spreading worldwide. The impact of the virus on the entire population and its differential effect on various age ... ...

Abstract	The COVID-19 (SARS-Cov-2) pandemic has put a strain on healthcare systems around the world from December 2019 in China, and then rapidly spreading worldwide. The impact of the virus on the entire population and its differential effect on various age groups was unknown at the outset, specifically its severity in elders, children or those living with other comorbidities, thus defining the syndemic, rather than pandemic, character of the infection. The effort of clinicians was initially to organize differential paths to isolate cases or contacts. This impacted the maternal-neonatal care adding an additional burden to this dyad and raising several questions. Can SARS-Cov-2 infection in the first days of life put the health of the newborn at risk? Could the separation of a healthy newborn from an infected mother create further physical and psychological health problems in the dyad? The rapid and massive research effort in these three years of the pandemic has provided wide answers to these initial questions. In this review, we report epidemiological data, clinical features, complications, and management of the neonates affected by SARS-Cov-2 infection.
MeSH term(s)	Infant, Newborn ; Child ; Humans ; Aged ; Pregnancy ; Female ; COVID-19/epidemiology ; SARS-CoV-2 ; Pandemics ; Family ; China ; Pregnancy Complications, Infectious/diagnosis ; Pregnancy Complications, Infectious/epidemiology ; Infectious Disease Transmission, Vertical
Language	English
Publishing date	2023-03-24
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	2174416-6
ISSN	1878-0946 ; 1744-165X
ISSN (online)	1878-0946
ISSN	1744-165X
DOI	10.1016/j.siny.2023.101430
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Article ; Online: Fatherhood during the COVID-19 pandemic: an unexpected turnaround.

Lista, Gianluca / Bresesti, Ilia

Early human development

2020 Volume 144, Page(s) 105048

MeSH term(s)	Attitude ; COVID-19 ; Coronavirus Infections/psychology ; Fathers/psychology ; Female ; Humans ; Infant, Newborn ; Male ; Pandemics ; Parenting/psychology ; Parturition/psychology ; Pneumonia, Viral/psychology ; Pregnancy
Keywords	covid19
Language	English
Publishing date	2020-04-24
Publishing country	Ireland
Document type	Letter
ZDB-ID	752532-1
ISSN	1872-6232 ; 0378-3782
ISSN (online)	1872-6232
ISSN	0378-3782
DOI	10.1016/j.earlhumdev.2020.105048
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Article ; Online: Management of the CDH patient on ECLS.

Martino, Alice / Lista, Gianluca / Guner, Yigit S

Seminars in fetal & neonatal medicine

2022 Volume 27, Issue 6, Page(s) 101407

Abstract: Congenital diaphragmatic hernia (CDH) is the most common indication for respiratory extracorporeal life support (ECLS) in neonates. The survival rate of CDH neonates treated with ECLS is 50%, and this figure has remained relatively stable over the last ... ...

Abstract	Congenital diaphragmatic hernia (CDH) is the most common indication for respiratory extracorporeal life support (ECLS) in neonates. The survival rate of CDH neonates treated with ECLS is 50%, and this figure has remained relatively stable over the last few decades. This is likely because the current population of CDH neonates who require ECLS have a higher risk profile [1]. The management of neonates with CDH has evolved over time to emphasize postnatal stabilization, gentle ventilation, and multi-modal treatment of pulmonary hypertension. In order to minimize practice variation, many centers have adopted CDH-specific clinical practice guidelines, however care is not standardized between different centers and outcomes vary [3]. The purpose of this review is to summarize our current understanding of issues central to the care of neonates with CDH treated with ECLS and specifically highlight how the use of the Extracorporeal Life Support Organization (ELSO) data have added to our understanding of CDH.
MeSH term(s)	Infant, Newborn ; Humans ; Hernias, Diaphragmatic, Congenital/surgery ; Extracorporeal Membrane Oxygenation ; Survival Rate ; Hypertension, Pulmonary ; Retrospective Studies
Language	English
Publishing date	2022-11-17
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	2174416-6
ISSN	1878-0946 ; 1744-165X
ISSN (online)	1878-0946
ISSN	1744-165X
DOI	10.1016/j.siny.2022.101407
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Article: Staphylococcus capitis

Sala, Anna / Pivetti, Valentina / Vittorini, Alessandra / Viggiano, Claudia / Castoldi, Francesca / Fabiano, Valentina / Lista, Gianluca / Cavigioli, Francesco

Pathogens (Basel, Switzerland)

2024 Volume 13, Issue 3

Abstract: Coagulase-negative staphylococci (CoNS) are reportedly responsible for 50-60% of bloodstream infections in very preterm (<1500 g) infants in neonatal intensive care units (NICUs). ...

Abstract	Coagulase-negative staphylococci (CoNS) are reportedly responsible for 50-60% of bloodstream infections in very preterm (<1500 g) infants in neonatal intensive care units (NICUs).
Language	English
Publishing date	2024-03-07
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2695572-6
ISSN	2076-0817
ISSN	2076-0817
DOI	10.3390/pathogens13030234
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Article ; Online: Respiratory Support of Neonate Affected by Bronchiolitis in Neonatal Intensive Care Unit.

Bresesti, Ilia / Lista, Gianluca

American journal of perinatology

2020 Volume 37, Issue S 02, Page(s) S10–S13

Abstract: Acute respiratory infections are very common medical emergency in early infancy, often requiring hospitalization. The most frequent respiratory infection at this stage of life is bronchiolitis, with a benign course in the majority of cases. However, ... ...

Abstract	Acute respiratory infections are very common medical emergency in early infancy, often requiring hospitalization. The most frequent respiratory infection at this stage of life is bronchiolitis, with a benign course in the majority of cases. However, especially during neonatal period, infants are at higher risk for developing complications, and ventilatory support of various degrees is needed. The two most widespread methods to provide noninvasive respiratory support are heated humidified high-flow nasal cannula and nasal continuous positive airway pressure. They are both used in neonatal intensive care unit to treat respiratory distress syndrome of the premature infants, and the main concept of recruiting and distending alveoli is valid also for respiratory failure occurring during bronchiolitis. However, there is still ongoing debate about the superiority of one method, and their real efficacy still need to be confirmed. Once respiratory failure does not respond to noninvasive ventilation, more intensive care must be provided in the form of conventional mechanical ventilation or high-frequency ventilation. There is currently no evidence of the optimal ventilation strategy to use, and a deeper comprehension of the pulmonary mechanics during bronchiolitis would be desirable to tailor ventilation according to the degree of severity. Further research is then urgently needed to better clarify these aspects. KEY POINTS: · Guidelines on the management of bronchiolitis in neonatal population are lacking.. · Noninvasive respiratory support is mostly delivered with HHHFNC and nCPAP.. · A deeper comprehension of the pulmonary mechanics during bronchiolitis is crucial to tailor invasive ventilation..
MeSH term(s)	Bronchiolitis/therapy ; Humans ; Infant, Newborn ; Intensive Care Units, Neonatal ; Oxygen Inhalation Therapy/adverse effects ; Oxygen Inhalation Therapy/methods ; Respiration, Artificial/adverse effects ; Respiration, Artificial/methods ; Respiratory Distress Syndrome, Newborn/therapy ; Respiratory Insufficiency/therapy
Language	English
Publishing date	2020-09-08
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	605671-4
ISSN	1098-8785 ; 0735-1631
ISSN (online)	1098-8785
ISSN	0735-1631
DOI	10.1055/s-0040-1713604
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Article: Preterm Birth and Maternal Mood States: What Is the Impact on Bonding?

Ionio, Chiara / Ciuffo, Giulia / Colombo, Caterina / Melani, Olivia / Figlino, Maria Francesca / Landoni, Marta / Castoldi, Francesca / Cavigioli, Francesco / Lista, Gianluca

Pediatric reports

2024 Volume 16, Issue 1, Page(s) 35–45

Abstract: Preterm birth is a significant global health issue affecting millions of infants each year, with potential implications for their developmental outcomes. This study investigated the impact of preterm birth on maternal mood states during the early ... ...

Abstract	Preterm birth is a significant global health issue affecting millions of infants each year, with potential implications for their developmental outcomes. This study investigated the impact of preterm birth on maternal mood states during the early postpartum period and its subsequent effects on mother-infant bonding. Mothers of 90 preterm infants were involved in the assessment of maternal mood states, examined with the Profile of Mood States (POMS) questionnaire and the evaluation of mother-infant bonding, carried out through the Postpartum Bonding Questionnaire (PBQ). Contrary to expectations, there was no significant correlation between preterm birth characteristics and maternal mood states. On the other hand, significant correlations emerged between specific maternal mood states and the quality of mother-child bonding. More specifically, regression analyses showed that feelings of tension, anger, and confusion experienced by the mother tend to negatively affect the quality of her bond with her child. These findings emphasize the crucial role of maternal mental well-being in shaping the mother-infant relationship in the early postpartum period. The study highlights the importance of identifying and addressing maternal mood disorders to promote positive mother-infant bonding and child development, further underlining the need for comprehensive support and interventions for mothers of preterm infants.
Language	English
Publishing date	2024-01-05
Publishing country	Switzerland
Document type	Journal Article
ISSN	2036-749X
ISSN	2036-749X
DOI	10.3390/pediatric16010004
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Article ; Online: Preterm Infants' Airway Microbiome: A Scoping Review of the Current Evidence.

Colombo, Sofia Fatima Giuseppina / Nava, Chiara / Castoldi, Francesca / Fabiano, Valentina / Meneghin, Fabio / Lista, Gianluca / Cavigioli, Francesco

Nutrients

2024 Volume 16, Issue 4

Abstract: The aim of this scoping review was to investigate and synthesize existing evidence on the airway microbiome of preterm infants to outline the prognostic and therapeutic significance of these microbiomes within the preterm population and identify gaps in ... ...

Abstract	The aim of this scoping review was to investigate and synthesize existing evidence on the airway microbiome of preterm infants to outline the prognostic and therapeutic significance of these microbiomes within the preterm population and identify gaps in current knowledge, proposing avenues for future research. We performed a scoping review of the literature following the Arskey and O'Malley framework. In accordance with our inclusion criteria and the intended purpose of this scoping review, we identified a total of 21 articles. The investigation of the airway microbiome in preterm infants has revealed new insights into its unique characteristics, highlighting distinct dynamics when compared to term infants. Perinatal factors, such as the mode of delivery, chorioamnionitis, the respiratory support, and antibiotic treatment, could impact the composition of the airway microbiome. The 'gut-lung axis', examining the link between the lung and gut microbiome as well as modifications in respiratory microbiome across different sites and over time, has also been explored. Furthermore, correlations between the airway microbiome and adverse outcomes, such as bronchopulmonary dysplasia (BPD), have been established. Additional research in neonatal care is essential to understand the early colonization of infants' airways and explore methods for its optimization. The critical opportunity to shape long-term health through microbiome-mediated effects likely lies within the neonatal period.
MeSH term(s)	Infant ; Pregnancy ; Female ; Infant, Newborn ; Humans ; Infant, Premature ; Lung ; Bronchopulmonary Dysplasia ; Microbiota ; Gastrointestinal Microbiome
Language	English
Publishing date	2024-02-06
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu16040465
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Article ; Online: Synchronized Invasive Mechanical Ventilation.

Bresesti, Ilia / Agosti, Massimo / Lakshminrusimha, Satyan / Lista, Gianluca

Clinics in perinatology

2021 Volume 48, Issue 4, Page(s) 813–824

Abstract: Respiratory care of premature neonates has witnessed substantial advances in the last two decades and has played a crucial role in decreasing early mortality in this population. This review outlines advances in techniques of synchronization and modes of ... ...

Abstract	Respiratory care of premature neonates has witnessed substantial advances in the last two decades and has played a crucial role in decreasing early mortality in this population. This review outlines advances in techniques of synchronization and modes of synchronized invasive mechanical ventilation in neonates. The use of synchronized ventilation in the neonatal population was delayed as compared to adults, mainly because of technical reasons. Coordinating the infant's respiratory effort and the onset of mechanical ventilation in the neonatal population has requested high sensitivity instruments.
MeSH term(s)	Humans ; Infant ; Infant, Newborn ; Infant, Premature ; Lung ; Respiration, Artificial
Language	English
Publishing date	2021-10-02
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	193116-7
ISSN	1557-9840 ; 0095-5108
ISSN (online)	1557-9840
ISSN	0095-5108
DOI	10.1016/j.clp.2021.07.008
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Article ; Online: Umbilical cord stump medication with a topical dermo protective powder compared to dry care in healthy full-term and near-term newborns: a two-center prospective cohort study.

Barilli, Francesca / Basile, Cecilia / DE Bernardo, Giuseppe / Morlino, Francesca / Manganelli, Giulia / Giordano, Maurizio / Bastrenta, Petrina / Zuccotti, Gian V / Lista, Gianluca

Minerva pediatrics

2024

Abstract: Background: Proper umbilical cord stump care during the first days of life (both in hospital and at home) should not be overlooked to prevent possible complications (e.g., purulent discharge, granulomas, or periumbilical erythema or omphalitis). Despite ...

Abstract	Background: Proper umbilical cord stump care during the first days of life (both in hospital and at home) should not be overlooked to prevent possible complications (e.g., purulent discharge, granulomas, or periumbilical erythema or omphalitis). Despite the known benefits of its correct execution, the care of umbilical cord stump remains controversial, and many different approaches are described. The World Health Organization suggests the use of dry cord stump care (easy and economic technique) in developed countries, but in many cases in the real life various topical antiseptics are used in combination with dry cord stump. The extracts of Arnica Montana (AM) have been reported to possess antibacterial, anti-inflammatory, antifungal, and immunomodulatory activities, very useful in the management of cord stump in full term infants. Methods: In our study we evaluated the efficacy of a powder containing AM (study group- GrA) versus dry cord stump (control group-GrB) in a population of healthy newborn >35 weeks of gestational age (GA). Results: Three hundred twenty-six neonates (mean GA 39±1 in both groups and body weight 3200 g and 3400±448 g respectively in GrA and GrB) were enrolled in two standard neonatal care units (163 neonates in GrA and 163 in GrB). At T1 (48 hours after discharge) GrA showed significantly reduced incidence of mild complications in toto, in particular a lower rate of wet umbilical cord stump). No differences between the two groups at T2 (1 week after discharge). Conclusions: The use of a natural topical dermo-protective powder containing AM reduces the risk of minor complications, both nurse and parental workload in the first days after discharge, but does not have an impact on cord detachment and other complications in neonates >35 weeks GA.
Language	English
Publishing date	2024-02-06
Publishing country	Italy
Document type	Journal Article
ZDB-ID	3062664-X
ISSN	2724-5780
ISSN (online)	2724-5780
DOI	10.23736/S2724-5276.23.07411-6
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