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  1. Article ; Online: Activated sludge microbiome with H

    Oh, Seungdae / Nguyen, Hiep T

    Environmental research

    2023  Volume 236, Issue Pt 2, Page(s) 116832

    Abstract: The widespread presence of oxytetracycline (OTC) in aquatic ecosystems poses both health risks and ecological concerns. The present study revealed the beneficial role of hydrogen peroxide ( ... ...

    Abstract The widespread presence of oxytetracycline (OTC) in aquatic ecosystems poses both health risks and ecological concerns. The present study revealed the beneficial role of hydrogen peroxide (H
    Language English
    Publishing date 2023-08-04
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2023.116832
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 726: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Strain-induced phase transitions and high carrier mobility in two-dimensional Janus MGeSN

    Nhan, Le C / Hiep, Nguyen T / Nguyen, Cuong Q / Hieu, Nguyen N

    Physical chemistry chemical physics : PCCP

    2023  Volume 25, Issue 27, Page(s) 18075–18085

    Abstract: In this study, we construct new 2D Janus ... ...

    Abstract In this study, we construct new 2D Janus MGeSN
    Language English
    Publishing date 2023-07-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d3cp01647a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Relationship of Recurrence Rate with some Characteristics in Patients with Thyroid Carcinoma.

    Tri, Bui D M / Chi, Bui D P / Hiep, Bui T / Trung, Nguyen H / Minh, Tong D / Dung, Nguyen T N / Bui, Thanh D / Tran, Viet Q / Nguyen, Hiep T

    Indian journal of endocrinology and metabolism

    2024  Volume 27, Issue 6, Page(s) 544–551

    Abstract: Background: Determining the clinical and subclinical characteristics related to the recurrence status in patients with a thyroid carcinoma has great significance for prognosis, prediction of recurrence and monitoring of treatment outcomes. This study ... ...

    Abstract Background: Determining the clinical and subclinical characteristics related to the recurrence status in patients with a thyroid carcinoma has great significance for prognosis, prediction of recurrence and monitoring of treatment outcomes. This study aimed to determine the association between recurrence rate and some characteristics in patients with thyroid carcinoma.
    Patients and methods: The study was conducted by descriptive method with longitudinal follow-up on 102 thyroid carcinoma patients at 103 Military Hospital, Hanoi, Vietnam, from July 2013 to December 2016.
    Results: Univariate analysis showed that there was a relationship between the recurrence characteristics in the studied patients and the characteristics of lymph node metastasis (
    Conclusion: There is a positive correlation between recurrence and masculinity, lymph node metastasis and the occurrence of BRAF V600E mutations in thyroid carcinoma patients.
    Language English
    Publishing date 2024-01-11
    Publishing country India
    Document type Journal Article
    ZDB-ID 2600211-5
    ISSN 2230-9500 ; 2230-8210
    ISSN (online) 2230-9500
    ISSN 2230-8210
    DOI 10.4103/ijem.ijem_134_23
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  4. Article ; Online: Activated sludge microbiome with H2O2-modified biochar enhances the treatment resilience and detoxification of oxytetracycline and its toxic byproducts

    Oh, Seungdae / Nguyen, Hiep T.

    Environmental Research. 2023 Nov., v. 236 p.116832-

    2023  

    Abstract: The widespread presence of oxytetracycline (OTC) in aquatic ecosystems poses both health risks and ecological concerns. The present study revealed the beneficial role of hydrogen peroxide (H₂O₂)-pretreated biochar (BC) derived from agricultural hardwood ... ...

    Abstract The widespread presence of oxytetracycline (OTC) in aquatic ecosystems poses both health risks and ecological concerns. The present study revealed the beneficial role of hydrogen peroxide (H₂O₂)-pretreated biochar (BC) derived from agricultural hardwood waste in an activated sludge (AS) bioprocess. The BC addition significantly enhanced the removal and detoxification of OTC and its byproducts. BC was initially modified using H₂O₂ to improve its OTC adsorption. Two AS reactors were then established, one with H₂O₂-modified BC and one without, and both were exposed to OTC. The BC-added reactor exhibited significantly higher OTC removal rates during both the start-up (0.97 d⁻¹) and steady-state (0.98 d⁻¹) phases than the reactor without BC (0.54 d⁻¹ and 0.83 d⁻¹, respectively). Two novel transformation pathways for OTC were proposed, with four byproducts originating from OTC identified, some of which were found to be more toxic than OTC itself. The BC-added reactor had significantly higher system functioning in terms of its heterotrophic activity and the reduction of the toxicity of OTC and its byproducts, as illustrated by structure-based toxicity simulations, antimicrobial susceptibility experiments, analytical chemistry, and bioinformatics analysis. Bioinformatics revealed two novel bacterial populations closely related to the known OTC-degrader Pandoraea. The ecophysiology and selective enrichment of these populations suggested their role in the enzymatic breakdown and detoxification of OTC (e.g., via demethylation and hydrogenation). Overall, the present study highlighted the beneficial role of H₂O₂-modified BC in combination with the AS microbiome in terms of enhancing treatment performance and resilience, reducing the toxicological disruption to biodiversity, and detoxifying micropollutants.
    Keywords Pandoraea ; activated sludge ; adsorption ; analytical chemistry ; antibiotic resistance ; biochar ; biodiversity ; bioinformatics ; bioprocessing ; demethylation ; ecophysiology ; hardwood ; hydrogen peroxide ; hydrogenation ; microbiome ; oxytetracycline ; pollutants ; research ; toxicity ; toxicology ; Biodegradation ; Detoxification
    Language English
    Dates of publication 2023-11
    Publishing place Elsevier Inc.
    Document type Article ; Online
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2023.116832
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 726: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Crystal lattice and electronic and transport properties of Janus ZrSiSZ

    Anh, Nguyen P Q / Hiep, Nguyen T / Lu, D V / Nguyen, Cuong Q / Hieu, Nguyen N / Vi, Vo T T

    Nanoscale advances

    2023  Volume 5, Issue 23, Page(s) 6705–6713

    Abstract: From the extending requirements for using innovative materials in advanced technologies, it is necessary to explore new materials for relevant applications. In this work, we design new two-dimensional (2D) Janus ... ...

    Abstract From the extending requirements for using innovative materials in advanced technologies, it is necessary to explore new materials for relevant applications. In this work, we design new two-dimensional (2D) Janus ZrSiSZ
    Language English
    Publishing date 2023-10-24
    Publishing country England
    Document type Journal Article
    ISSN 2516-0230
    ISSN (online) 2516-0230
    DOI 10.1039/d3na00631j
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Environmental consequences of transformation products from an antibiotic mixture and their mitigation in a wastewater microbiome using an HCl-modified adsorbent.

    Nguyen, Hiep T / Maeng, Sung Kyu / Lee, Tae Kwon / Oh, Seungdae

    Bioresource technology

    2024  Volume 395, Page(s) 130402

    Abstract: This study enhanced our understanding of antibiotic mixtures' occurrence, transformation, toxicity, and ecological risks. The role of acid-modified biochar (BC) in treating antibiotic residues was explored, shedding light on how BC influences the fate, ... ...

    Abstract This study enhanced our understanding of antibiotic mixtures' occurrence, transformation, toxicity, and ecological risks. The role of acid-modified biochar (BC) in treating antibiotic residues was explored, shedding light on how BC influences the fate, mobility, and environmental impact of antibiotics and transformation products (TPs) in an activated sludge (AS) microbiome. A mixture of oxytetracycline and sulfamethoxazole was found to synergistically (or additively) inhibit cell growth of AS and disrupt the microbiome structure, species richness/diversity, and function. The formation of TPs with potentially higher toxicity and persistence than the original compounds was identified, explaining the microbiome disruption. Agricultural waste-derived BC was optimized for contaminant adsorption, leading to a reduction in toxicity when added to AS by sequestering TPs on its surface. This work highlighted adsorbents as a practical engineering strategy for mitigating liquid-phase contaminants' toxicological consequences, proactively controlling the fate and effects of antibiotics and TPs.
    MeSH term(s) Anti-Bacterial Agents/chemistry ; Wastewater ; Water Pollutants, Chemical/metabolism ; Sewage ; Sulfamethoxazole ; Charcoal
    Chemical Substances Anti-Bacterial Agents ; Wastewater ; Water Pollutants, Chemical ; Sewage ; Sulfamethoxazole (JE42381TNV) ; biochar ; Charcoal (16291-96-6)
    Language English
    Publishing date 2024-01-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 1065195-0
    ISSN 1873-2976 ; 0960-8524
    ISSN (online) 1873-2976
    ISSN 0960-8524
    DOI 10.1016/j.biortech.2024.130402
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 3258: Show issues

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  7. Article ; Online: Two-dimensional Janus MGeSiP

    Hiep, Nguyen T / Anh, Nguyen P Q / Phuc, Huynh V / Nguyen, Cuong Q / Hieu, Nguyen N / Vi, Vo T T

    Physical chemistry chemical physics : PCCP

    2023  Volume 25, Issue 12, Page(s) 8779–8788

    Abstract: Novel Janus materials have attracted broad interest due to the outstanding properties created by their out-of-plane asymmetry, with increasing theoretical exploration and more reports of successful fabrication in recent years. Here, we construct and ... ...

    Abstract Novel Janus materials have attracted broad interest due to the outstanding properties created by their out-of-plane asymmetry, with increasing theoretical exploration and more reports of successful fabrication in recent years. Here, we construct and explore the crystal structures, stabilities, electronic band structures, and transport properties - including carrier mobilities - of two-dimensional Janus MGeSiP
    Language English
    Publishing date 2023-03-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d3cp00188a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Moderate direct band-gap energies and high carrier mobilities of Janus XWSiP

    Nguyen, Hiep T / Cuong, Nguyen Q / Vi, Vo T T / Hieu, Nguyen N / Tran, Linh P T

    Physical chemistry chemical physics : PCCP

    2023  Volume 25, Issue 32, Page(s) 21468–21478

    Abstract: Two-dimensional (2D) Janus materials with extraordinary properties are promising candidates for utilization in advanced technologies. In this study, new 2D Janus ... ...

    Abstract Two-dimensional (2D) Janus materials with extraordinary properties are promising candidates for utilization in advanced technologies. In this study, new 2D Janus XWSiP
    Language English
    Publishing date 2023-08-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d3cp02037a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Accurate dilated renal pelvis measurement: reply to Mihmanli.

    Nguyen, Hiep T / Phelps, Andrew / Coley, Brian / Darge, Kassa / Rhee, Audrey / Chow, Jeanne S

    Pediatric radiology

    2023  Volume 53, Issue 6, Page(s) 1217

    MeSH term(s) Humans ; Kidney Diseases ; Kidney Pelvis/diagnostic imaging
    Language English
    Publishing date 2023-02-28
    Publishing country Germany
    Document type Letter
    ZDB-ID 124459-0
    ISSN 1432-1998 ; 0301-0449
    ISSN (online) 1432-1998
    ISSN 0301-0449
    DOI 10.1007/s00247-023-05609-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 927: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  10. Article ; Online: Differential requirement for IL-2 and IL-23 in the differentiation and effector functions of Th17/ILC3-like cells in a human T cell line.

    Sarah, Momtazkari / Anahita, Dev Choudhury / Zachary, Wei Ern Yong / Thanh, Dong Le / Hiep, Nguyen Canh / Kenichi, Harada / Hori, Toshiyuki / Motomi, Osato / Chiaki, Takahashi / Koh, Cai Ping / Dominic, Chih-Cheng Voon

    Journal of leukocyte biology

    2024  

    Abstract: A well-documented Achilles heel of current cancer immunotherapy approaches is T cell exhaustion ... chimeric antigen receptor (CAR)-T cells survival and tumor immunity. However, in-depth interrogation ... differentiation of the IL-23 responsive Kit225 T-cell line. We observed that IL-23 enhanced cellular fitness and ...

    Abstract A well-documented Achilles heel of current cancer immunotherapy approaches is T cell exhaustion within solid tumor tissues. The pro-inflammatory cytokine interleukin-23 (IL-23) has been utilised to augment chimeric antigen receptor (CAR)-T cells survival and tumor immunity. However, in-depth interrogation of molecular events downstream of IL-23/IL23R signaling is hampered by a paucity of suitable cell models. The current study investigates the differential contribution of IL-2 and IL-23 to the maintenance and differentiation of the IL-23 responsive Kit225 T-cell line. We observed that IL-23 enhanced cellular fitness and survival but was insufficient to drive proliferation. IL-23 rapidly induced phosphorylation of STAT1, 3 and 4, and mRNA expression of IL17A, the archetypal effector cytokine of Th17 cells, but not their lineage markers RORC and NCR1. These observations suggest that IL-23 endowed Th17/ILC3-like effector function but did not promote their differentiation. In contrast, spontaneous differentiation of Kit225 cells towards a Th17/ILC3-like phenotype was induced by prolonged IL-2 withdrawal. This was marked by strongly elevated basal IL17A and IL17F expression and the secretion of IL-17. Together, our data present Kit225 cells as a valuable model for studying the interplay between cytokines and their contribution to T cell survival, proliferation, and differentiation.
    Language English
    Publishing date 2024-02-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 605722-6
    ISSN 1938-3673 ; 0741-5400
    ISSN (online) 1938-3673
    ISSN 0741-5400
    DOI 10.1093/jleuko/qiae034
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    Zs.A 603: Show issues Location:
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