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  1. Article ; Online: Y

    Tai, Yuehui / Zhang, Yu / Sun, Jinlong / Liu, Fuyue / Tian, Haoran / Liu, Qifeng / Li, Caihong

    RSC advances

    2021  Volume 11, Issue 39, Page(s) 24044–24053

    Abstract: Endowing photocatalytic materials with a broader range of light responses is important for improving their performance and solar energy utilization. In this study, a simple sol-gel method was used to prepare ... ...

    Abstract Endowing photocatalytic materials with a broader range of light responses is important for improving their performance and solar energy utilization. In this study, a simple sol-gel method was used to prepare Yb
    Language English
    Publishing date 2021-07-07
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d1ra03066c
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Y

    Li, Xue / Li, Chen / Gao, Linhui / Zhu, Hongliang / Wang, Longcheng / Chen, Jing / Li, Yongtao / Zheng, Jinsheng

    Applied optics

    2020  Volume 59, Issue 27, Page(s) 8205–8210

    Abstract: At present, the most common materials for solar-blind UV light detectors are wide band-gap semiconductors, which generally have high requirements and complex methods for preparation. Ordinary semiconductor materials such as silicon, ...

    Abstract At present, the most common materials for solar-blind UV light detectors are wide band-gap semiconductors, which generally have high requirements and complex methods for preparation. Ordinary semiconductor materials such as silicon,
    Language English
    Publishing date 2020-09-25
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4522
    ISSN (online) 1539-4522
    DOI 10.1364/AO.400961
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Y

    Li, Juan / Du, Yang / Jiang, Zhenqi / Tian, Yuchen / Qiu, Nianxiang / Wang, Yinjie / Lqbal, Muhammad Zubair / Hu, Menying / Zou, Ruifen / Luo, Lijia / Du, Shiyu / Tian, Jie / Wu, Aiguo

    Nanoscale

    2018  Volume 10, Issue 13, Page(s) 5845–5851

    Abstract: ... ligands for glioma imaging and therapy remains challenging. Neuropeptide Y (NPY) Y1 receptors (Y1Rs) are ...

    Abstract Due to the molecular and cellular heterogeneity of glioma, discovery of novel targeted sites and ligands for glioma imaging and therapy remains challenging. Neuropeptide Y (NPY) Y1 receptors (Y1Rs) are highly over expressed in various brain tumors including glioma, and can serve as potential targeting sites for glioma imaging and therapy. Here, we show by in vivo fluorescent imaging that a highly selective Y1R ligand, [Asn6, Pro34] NPY (AP-NPY), facilitated circumvention of the blood brain barrier (BBB) by nanomicelles specifically targeting glioma. Modification with AP-NPY stabilized doxorubicin-loaded nanomicelles in the normal physiological state and promoted drug release in the acidic tumor microenvironment. Furthermore, targeted delivery of AP-NPY nanomicelles improved the therapeutic efficacy of doxorubicin for glioma, producing a prolonged survival rate. These results suggest that Y1R is a novel targeted receptor, and its selective ligand AP-NPY improves BBB permeability and glioma targeting. Our study paves the way for developing a novel delivery system for diagnosis and treatment of glioma in which Y1Rs are over expressed.
    MeSH term(s) Animals ; Blood-Brain Barrier ; Brain Neoplasms/diagnostic imaging ; Brain Neoplasms/drug therapy ; Cell Line, Tumor ; Doxorubicin/administration & dosage ; Endothelial Cells ; Glioma/diagnostic imaging ; Glioma/drug therapy ; Humans ; Ligands ; Mice ; Mice, Nude ; Micelles ; Nanoparticles ; Neoplasms, Experimental/diagnostic imaging ; Neoplasms, Experimental/drug therapy ; Optical Imaging ; Protein Binding ; Receptors, Neuropeptide Y/metabolism
    Chemical Substances Ligands ; Micelles ; Receptors, Neuropeptide Y ; neuropeptide Y-Y1 receptor ; Doxorubicin (80168379AG)
    Language English
    Publishing date 2018-03-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2515664-0
    ISSN 2040-3372 ; 2040-3364
    ISSN (online) 2040-3372
    ISSN 2040-3364
    DOI 10.1039/c8nr00148k
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Y

    Yu, Zhangsen / Xia, Yuanzhi / Xing, Jie / Li, Zihou / Zhen, Jianjun / Jin, Yinhua / Tian, Yuchen / Liu, Chuang / Jiang, Zhenqi / Li, Juan / Wu, Aiguo

    Nanoscale

    2018  Volume 10, Issue 36, Page(s) 17038–17052

    Abstract: Achieving efficient photodynamic therapy (PDT) in deeper biological tissue is still the biggest bottleneck that limits its widespread application in clinic. Although deeper biological tissue PDT could be realized through a combination of upconversion ... ...

    Abstract Achieving efficient photodynamic therapy (PDT) in deeper biological tissue is still the biggest bottleneck that limits its widespread application in clinic. Although deeper biological tissue PDT could be realized through a combination of upconversion nanoparticles with a photosensitizer, issues with particle-size-induced upconversion fluorescence (UF) reduction and the related in vivo toxicity still cannot be solved properly. In this study, we synthesized Y1Rs-ligand [Pro30, Nle31, Bpa32, Leu34]NPY(28-36) (NPY)-modified and photosensitizer MC540-loaded LiLuF4:Yb,Er@nLiGdF4@mSiO2 multifunctional nanocomposites (MNPs) with a core-multishell structure and ultrasmall size. Their in vitro and in vivo breast tumor targeting, trimodality imaging performance, PDT therapeutic efficacy, and acute toxicity were evaluated. Our results demonstrated that the core-multishell MNPs(MC540) could achieve excellent UF imaging, and that doping with Gd3+ and Lu3+ rare earth ions could enhance the MR and CT imaging performance. In addition, the mSiO2 shell provided a higher loading rate for the photosensitizer MC540, and the DSPE-PEG thin layer coating outside the MNPs(MC540) further improved the water solubility and biocompatibility, reducing the acute toxicity of the nanocomposites. Finally, the NPY modification enhanced the targetability of MNPs(MC540)/DSPE-PEG-NPY to breast tumors, improving the trimodality UF, CT, and MR imaging performance and PDT efficacy for Y1-receptor-overexpressed breast cancer. In general, our developed multifunctional nanocomposites can serve as a theranostic agent with low toxicity, providing great potential for their use in clinical breast cancer diagnosis and therapy.
    MeSH term(s) Animals ; Cell Line, Tumor ; Female ; Humans ; MCF-7 Cells ; Mice, Inbred BALB C ; Mice, Inbred ICR ; Nanocomposites/chemistry ; Nanoparticles/chemistry ; Neoplasms, Experimental/drug therapy ; Photochemotherapy ; Photosensitizing Agents/pharmacology ; Xenograft Model Antitumor Assays
    Chemical Substances Photosensitizing Agents
    Language English
    Publishing date 2018-04-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2515664-0
    ISSN 2040-3372 ; 2040-3364
    ISSN (online) 2040-3372
    ISSN 2040-3364
    DOI 10.1039/c8nr02387e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Y

    Yang, Zhou / Sheng, Jiangyuan / Lv, Ke / Ren, Li / Zhang, Di

    Plant science : an international journal of experimental plant biology

    2019  Volume 284, Page(s) 143–160

    Abstract: Two dehydrins from Agapanthus praecox ( ... ...

    Abstract Two dehydrins from Agapanthus praecox (ApY
    MeSH term(s) Amaryllidaceae/genetics ; Amaryllidaceae/metabolism ; Amaryllidaceae/physiology ; Escherichia coli ; Gene Expression Regulation, Plant ; Hydroxyl Radical/metabolism ; Organisms, Genetically Modified ; Phylogeny ; Plant Proteins/genetics ; Plant Proteins/physiology ; Plants, Genetically Modified ; Sequence Analysis, DNA ; Stress, Physiological/physiology
    Chemical Substances Plant Proteins ; dehydrin proteins, plant (134711-03-8) ; Hydroxyl Radical (3352-57-6)
    Language English
    Publishing date 2019-03-20
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 742010-9
    ISSN 1873-2259 ; 0168-9452
    ISSN (online) 1873-2259
    ISSN 0168-9452
    DOI 10.1016/j.plantsci.2019.03.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 77/717: Show issues

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  6. Article ; Online: Correction: A Y

    Wang, Yinjie / Jiang, Zhenqi / Yuan, Bo / Tian, Yuchen / Xiang, Lingchao / Li, Yanying / Yang, Yong / Li, Juan / Wu, Aiguo

    Biomaterials science

    2024  Volume 12, Issue 8, Page(s) 2165–2166

    Abstract: Correction for 'A Y1 receptor ligand synergized with a P-glycoprotein inhibitor improves the therapeutic efficacy of multidrug resistant breast cancer' by Yinjie ... ...

    Abstract Correction for 'A Y1 receptor ligand synergized with a P-glycoprotein inhibitor improves the therapeutic efficacy of multidrug resistant breast cancer' by Yinjie Wang
    Language English
    Publishing date 2024-04-16
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2693928-9
    ISSN 2047-4849 ; 2047-4830
    ISSN (online) 2047-4849
    ISSN 2047-4830
    DOI 10.1039/d4bm90022g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Kinetic analysis of the crystallization of Y

    Zheng, Tao / Li, Minghan / Ma, Yanping / Jiang, Hong

    RSC advances

    2024  Volume 14, Issue 10, Page(s) 7052–7060

    Abstract: ... ...

    Abstract Li
    Language English
    Publishing date 2024-02-27
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d3ra07239h
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A Y

    Wang, Yinjie / Jiang, Zhenqi / Yuan, Bo / Tian, Yuchen / Xiang, Lingchao / Li, Yanying / Yang, Yong / Li, Juan / Wu, Aiguo

    Biomaterials science

    2019  Volume 7, Issue 11, Page(s) 4748–4757

    Abstract: ... to develop a novel strategy for its treatment. Based on the high overexpression of Y ...

    Abstract Multidrug resistance (MDR) is one of the main reasons for the inefficiency of cancer chemotherapy. As a consequence of MDR, the expression level of membrane proteins might be changed, which can thus be used to develop a novel strategy for its treatment. Based on the high overexpression of Y
    MeSH term(s) ATP Binding Cassette Transporter, Subfamily B, Member 1/antagonists & inhibitors ; ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism ; Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Breast Neoplasms/diagnostic imaging ; Breast Neoplasms/drug therapy ; Breast Neoplasms/metabolism ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Doxorubicin/chemistry ; Doxorubicin/pharmacology ; Drug Resistance, Multiple/drug effects ; Drug Resistance, Neoplasm/drug effects ; Drug Screening Assays, Antitumor ; Female ; Humans ; Ligands ; MCF-7 Cells ; Mammary Neoplasms, Experimental/diagnostic imaging ; Mammary Neoplasms, Experimental/drug therapy ; Mammary Neoplasms, Experimental/metabolism ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Micelles ; Nanoparticles/chemistry ; Optical Imaging ; Quinolines/chemistry ; Quinolines/pharmacology ; Receptors, Neuropeptide Y/antagonists & inhibitors ; Receptors, Neuropeptide Y/metabolism
    Chemical Substances ATP Binding Cassette Transporter, Subfamily B, Member 1 ; Antineoplastic Agents ; Ligands ; Micelles ; Quinolines ; Receptors, Neuropeptide Y ; Doxorubicin (80168379AG) ; tariquidar (J58862DTVD)
    Language English
    Publishing date 2019-09-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2693928-9
    ISSN 2047-4849 ; 2047-4830
    ISSN (online) 2047-4849
    ISSN 2047-4830
    DOI 10.1039/c9bm00337a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The pivotal role of bromine in FeMnKBr/Y

    Cui, Wenjie / Xia, Yudong / Zhang, Peipei / Fu, Yajie / Ye, Xue / Li, Jie / Tan, Li

    iScience

    2024  Volume 27, Issue 5, Page(s) 109621

    Abstract: ... on catalysts, we present the synthesis of FeMnKBr/Y ...

    Abstract Light olefins are key intermediates in the synthesis of petrochemicals, and the conversion of stabilized carbon dioxide to light olefins using catalysts containing halogenated elements such as chlorine is a major challenge. Building on previous reports emphasizing the toxic effects of halogen elements on catalysts, we present the synthesis of FeMnKBr/Y
    Language English
    Publishing date 2024-03-28
    Publishing country United States
    Document type Journal Article
    ISSN 2589-0042
    ISSN (online) 2589-0042
    DOI 10.1016/j.isci.2024.109621
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Preparation of Y

    Ren, Yu / Zhao, Ziyao / Jiang, Wenwen / Zhang, Guangyu / Tan, Yuxin / Guan, Yongyin / Zhou, Long / Cui, Li / Choi, Sung Woong / Li, Mei-Xian

    Polymers

    2022  Volume 14, Issue 14

    Abstract: In this study, Y ...

    Abstract In this study, Y
    Language English
    Publishing date 2022-07-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym14142760
    Database MEDical Literature Analysis and Retrieval System OnLINE

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