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Article ; Online: The diagnostic conundrum in necrotizing otitis externa.

Ahmed, Abiya A / Rashid, Shaan / Gupta, Vinay K / Molony, Neil C / Gupta, Keshav K

World journal of otorhinolaryngology - head and neck surgery

2023 Volume 10, Issue 1, Page(s) 59–65

Abstract: Necrotizing otitis externa (NOE) is an aggressive and fast-evolving infection of the external auditory canal. Late diagnoses and untreated cases can lead to severe, even fatal consequences and so early diagnosis and treatment are paramount. NOE is a ... ...

Abstract	Necrotizing otitis externa (NOE) is an aggressive and fast-evolving infection of the external auditory canal. Late diagnoses and untreated cases can lead to severe, even fatal consequences and so early diagnosis and treatment are paramount. NOE is a notoriously challenging diagnosis to make. It is therefore important to understand what diagnostic modalities are available and how otolaryngologists can use them to accurately treat such an aggressive disease. This review aims to evaluate the different diagnostic options available in NOE and discuss their advantages and limitations, thus, providing an up-to-date picture of the multimodal approach required in the diagnosis of this disease.
Language	English
Publishing date	2023-06-28
Publishing country	United States
Document type	Journal Article ; Review
ISSN	2589-1081
ISSN (online)	2589-1081
DOI	10.1002/wjo2.100
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Ovarian endometriosis with borderline serous tumor

Safia Rana / Arushi Gupta / Shaan Khetrapal / Zeeba Shamim Jairajpuri / Sujata Jetley / Aruna Nigam

Archives of Medicine and Health Sciences, Vol 11, Iss 2, Pp 271-

A rare occurrence

2023 Volume 273

Abstract: Endometriosis is a prevalent benign condition arising from the female reproductive system and affects about 7%–10% of females. The association of endometriosis with serous borderline ovarian tumors has been a matter of interest in gynecology. Sampson ... ...

Abstract	Endometriosis is a prevalent benign condition arising from the female reproductive system and affects about 7%–10% of females. The association of endometriosis with serous borderline ovarian tumors has been a matter of interest in gynecology. Sampson first described the association between endometriosis and carcinoma. The endometriosis-associated ovarian malignancies are clear cell adenocarcinoma and endometrioid adenocarcinoma, whereas serous and mucinous are rare malignancies associated with endometriosis. Here, we present the case report of a 45-year-old female in which endometriosis was associated with borderline serous tumor, since there is a lack of enough confident criteria for diagnosing endometriosis-associated ovarian tumors.
Keywords	endometriosis ; ovary ; serous ; Medicine ; R
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Wolters Kluwer Medknow Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Convenience as a dimension of food environments: A systematic scoping review of its definition and measurement.

Bogard, Jessica R / Downs, Shauna / Casey, Elodie / Farrell, Penny / Gupta, Adyya / Miachon, Lais / Naughton, Shaan / Staromiejska, Wiktoria / Reeve, Erica

Appetite

2024 Volume 194, Page(s) 107198

Abstract: Convenience is a major driver of food choice throughout the world, yet it is often inconsistently conceptualised, defined and measured. This limits the scope for food systems policy and interventions to leverage convenience to improve diet and nutrition ... ...

Abstract	Convenience is a major driver of food choice throughout the world, yet it is often inconsistently conceptualised, defined and measured. This limits the scope for food systems policy and interventions to leverage convenience to improve diet and nutrition outcomes. We conducted a systematic literature review to determine how convenience is both defined and measured in food environment and nutrition research. Six databases were systematically searched and studies were screened by two independent reviewers based on pre-defined eligibility criteria, yielding 243 studies for inclusion in the final review. 77% of studies did not explicitly define convenience. Among those that did, the dimensions and components within definitions varied. 83% of studies used perceived measures of convenience rather than objective measures. Convenience was most commonly measured in high income countries (64%) and in relation to the home food environment (53%), followed by formal retail (40%). Very few studies measured convenience in relation to the informal retail or cultivated food environments, and no studies considered convenience in relation to wild food environments. The vast majority of studies did not consider the validity or reliability of the measures of convenience. Based on our findings we propose a definition of convenience as a characteristic that results in reduced requirement for resources including time, physical effort, mental effort and skills by the consumer in relation to the planning, acquisition, preparation, storage, transport, consumption or clean-up of food. This definition can be used to help guide the development of measurement tools that can be used to assess convenience across different dimensions and contexts in a more comprehensive way. We also propose a framework for considering convenience as an entry point in food systems to improve diets and nutrition outcomes.
MeSH term(s)	Humans ; Reproducibility of Results ; Food ; Diet ; Food Preferences ; Marketing
Language	English
Publishing date	2024-01-02
Publishing country	England
Document type	Systematic Review ; Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	1461347-5
ISSN	1095-8304 ; 0195-6663
ISSN (online)	1095-8304
ISSN	0195-6663
DOI	10.1016/j.appet.2023.107198
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Article ; Online: Study of histochemical and immunohistochemical profile in grading of squamous cell carcinoma of the oral cavity

Arushi Gupta / Shaan Khetrapal / Safia Rana / Sujata Jetley / Seema Monga / Zeeba Shamim Jairajpuri

Archives of Medicine and Health Sciences, Vol 11, Iss 2, Pp 223-

2023 Volume 228

Abstract: Background and Aim: Head-and-neck cancers (HNCs) are significant causes of morbidity and mortality in both the developed and developing worlds. One of the most common types of HNC is oral squamous cell carcinoma (OSCC). The rationale behind the present ... ...

Abstract	Background and Aim: Head-and-neck cancers (HNCs) are significant causes of morbidity and mortality in both the developed and developing worlds. One of the most common types of HNC is oral squamous cell carcinoma (OSCC). The rationale behind the present study is to analyze the effectiveness of nuclear proliferative markers in comparison to the various grades of OSCC. This study utilizes Anneroth's histopathological multifactorial grading system for squamous cell carcinoma and further tends to compare this histological grading with nuclear proliferative indices of p53 and argyrophilic nucleolar organizer region (AgNOR). The aim of this study was to establish and develop a correlation between the proliferative markers, AgNOR and p53, and the histologic grade of the tumor (Anneroth's grading). Materials and Methods: A total of 60 cases of oral squamous cell carcinoma were taken from October 2020 to September 2022. The histological grading was done according to Anneroth's grading, and a score was given. P53 expression was graded according to the percentage of cells showing p53-positive immunostaining, and scoring was done from 0 to 3. The AgNOR score was calculated by examining 100 nuclei and calculating the mean AgNOR score per nucleus. Results: A significant linear correlation was obtained between the histological grading of OSCC and the proliferative markers (p53 and AgNOR). Conclusion: The analysis of the NOR count provides invaluable assistance in determining tumor aggressiveness and cellular proliferation rates. They can prove to be efficient tools to procure information on the malignant potential of different premalignant lesions. Elevated p53 expression implies greater clinical severity, a higher histological grade, and a poor prognosis for oral squamous cell carcinoma. Hence, the proliferative markers can be used as adjuncts to the histological grading system of OSCC.
Keywords	anneroth's grading ; argyrophilic nucleolar organizer regions ; oral squamous cell carcinoma ; p53 ; Medicine ; R
Subject code	616
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Wolters Kluwer Medknow Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Telemedicine, safe medication stewardship, and COVID-19: Digital transformation during a global pandemic.

Kulchar, Rachel J / Chen, Kaitlyn / Moon, Christina / Srinivas, Shaan / Gupta, Anita

Journal of interprofessional education & practice

2022 Volume 29, Page(s) 100524

Abstract: Telemedicine may provide equitable, accessible, and affordable healthcare to individuals globally. Recently tele-medicine has emerged as a vital resource for interdisciplinary healthcare professionals to provide critical medical care on the frontlines ... ...

Abstract	Telemedicine may provide equitable, accessible, and affordable healthcare to individuals globally. Recently tele-medicine has emerged as a vital resource for interdisciplinary healthcare professionals to provide critical medical care on the frontlines during the combined COVID-19 pandemic and the drug and opioid crisis. With the recent 2020 expansion of insurance coverage of telemedicine services by the United States Centers for Medicare & Medicaid Services, there has been an uptick in the need to understand how to comprehensively train physicians and health care professionals on telemedicine during a public health crisis. This study gathered 98 survey responses from interdisciplinary healthcare professionals regarding their telemedicine experience, focusing on trends of use with the drug and opioid crisis during the COVID-19 pandemic. The results demonstrate that during the COVID-19 pandemic, telemedicine provided a novel, innovative way to address an unmet need in healthcare and may aid to improve safe medication stewardship (SaMS) practice guidelines. Further expanded population-based research and randomized clinical trials are necessary to confirm these preliminary recommendations and form best practices for use in digital health and telemedicine. In addition, further studies will confirm the benefits of interdisciplinary healthcare professionals' engagement in harm reduction strategies via telemedicine to address improving safe medication use.
Language	English
Publishing date	2022-08-01
Publishing country	United States
Document type	Journal Article
ISSN	2405-4526
ISSN	2405-4526
DOI	10.1016/j.xjep.2022.100524
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Article ; Online: Insight into the gas phase dissociation of CF

Ameer, Shaan / Tomar, Monika / Jha, Pradip Kumar / Gupta, Vinay

Journal of molecular modeling

2018 Volume 24, Issue 11, Page(s) 315

Abstract: The Arrhenius kinetic parameters of dissociation reactions and reactions of ... ...

Abstract	The Arrhenius kinetic parameters of dissociation reactions and reactions of CF
Language	English
Publishing date	2018-10-17
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1284729-x
ISSN	0948-5023 ; 1610-2940
ISSN (online)	0948-5023
ISSN	1610-2940
DOI	10.1007/s00894-018-3847-9
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Article ; Online: The role of an unintentional carbon dopant in resolving the controversial conductivity aspects in BiFeO

Ameer, Shaan / Jindal, Kajal / Tomar, Monika / Jha, Pradip K / Gupta, Vinay

Physical chemistry chemical physics : PCCP

2020 Volume 22, Issue 18, Page(s) 10010–10026

Abstract: Light elements like carbon may enter unintentionally into a material during material processing owing to their ubiquitous nature, and may significantly influence its observed electronic and magnetic properties. In the present work, the energetics and ... ...

Abstract	Light elements like carbon may enter unintentionally into a material during material processing owing to their ubiquitous nature, and may significantly influence its observed electronic and magnetic properties. In the present work, the energetics and kinetics of carbon impurity related defects in BiFeO
Language	English
Publishing date	2020-04-27
Publishing country	England
Document type	Journal Article
ZDB-ID	1476244-4
ISSN	1463-9084 ; 1463-9076
ISSN (online)	1463-9084
ISSN	1463-9076
DOI	10.1039/c9cp06614d
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Article ; Online: Low Socioeconomic Status but Resilient: Panacea or Double Trouble? John Henryism in the International IMIAS Study of Older Adults.

Gupta, Shaan / Bélanger, Emmanuelle / Phillips, Susan P

Journal of cross-cultural gerontology

2018 Volume 34, Issue 1, Page(s) 15–24

Abstract: John Henry (JH) theory provides a framework for understanding the physiological toll exerted on low socioeconomic status (SES) individuals as they overcome psychosocial stressors imposed by their environments. This theory suggests that resilience, a ... ...

Abstract	John Henry (JH) theory provides a framework for understanding the physiological toll exerted on low socioeconomic status (SES) individuals as they overcome psychosocial stressors imposed by their environments. This theory suggests that resilience, a seemingly positive social adaptation, may in fact be physically deleterious. JH theory has been well-described in low-SES rural male African Americans, however it is currently unclear whether validity of this theory extends to women, other races and outside the rural US. We assessed whether, in individuals with low income, there is an association between self-mastery/resilience and either blood pressure or depressive symptoms that is different from the association seen in individuals with higher income. Data were obtained from 1353 older men and women participants of the International Mobility in Aging Study (IMIAS). Across 3 countries and 4 sites, higher self-mastery/resilience was associated with lower depressive symptoms in both low and high income groups. In low income individuals from Saint-Hyacinthe, Québec, higher self-mastery/resilience was associated with both higher mean systolic blood pressure (n = 240, β = 0.135, p ≤ 0.05) and higher mean diastolic blood pressure (n = 240, β = 0.241, p ≤ 0.0001). In the high income group of Saint-Hyacinthe, no such associations were observed. The findings in the Saint-Hyacinthe cohort (but not the other settings), are consistent with the John Henry hypothesis, and demonstrates this effect extends beyond a rural African American population. This finding indicates that in certain populations, the positive psychological effects of resilience come with a cost to physical health.
MeSH term(s)	Adaptation, Psychological ; Aged ; Aging/physiology ; Aging/psychology ; Blood Pressure Determination/methods ; Blood Pressure Determination/statistics & numerical data ; Canada ; Depression/physiopathology ; Female ; Health Status ; Humans ; Male ; Middle Aged ; Poverty/psychology ; Poverty/statistics & numerical data ; Psychological Theory ; Psychology ; Resilience, Psychological ; Self-Control/psychology ; Social Adjustment ; Socioeconomic Factors ; Stress, Psychological/physiopathology
Language	English
Publishing date	2018-12-04
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	644348-5
ISSN	1573-0719 ; 0169-3816
ISSN (online)	1573-0719
ISSN	0169-3816
DOI	10.1007/s10823-018-9362-8
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Article: Fecal microbiota transplantation: in perspective.

Gupta, Shaan / Allen-Vercoe, Emma / Petrof, Elaine O

Therapeutic advances in gastroenterology

2016 Volume 9, Issue 2, Page(s) 229–239

Abstract: There has been increasing interest in understanding the role of the human gut microbiome to elucidate the therapeutic potential of its manipulation. Fecal microbiota transplantation (FMT) is the administration of a solution of fecal matter from a donor ... ...

Abstract	There has been increasing interest in understanding the role of the human gut microbiome to elucidate the therapeutic potential of its manipulation. Fecal microbiota transplantation (FMT) is the administration of a solution of fecal matter from a donor into the intestinal tract of a recipient in order to directly change the recipient's gut microbial composition and confer a health benefit. FMT has been used to successfully treat recurrent Clostridium difficile infection. There are preliminary indications to suggest that it may also carry therapeutic potential for other conditions such as inflammatory bowel disease, obesity, metabolic syndrome, and functional gastrointestinal disorders.
Language	English
Publishing date	2016-02-23
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2440710-0
ISSN	1756-2848 ; 1756-283X
ISSN (online)	1756-2848
ISSN	1756-283X
DOI	10.1177/1756283X15607414
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Book ; Online: What sets Verified Users apart? Insights, Analysis and Prediction of Verified Users on Twitter

Paul, Indraneil / Khattar, Abhinav / Chopra, Shaan / Kumaraguru, Ponnurangam / Gupta, Manish

2019

Abstract: Social network and publishing platforms, such as Twitter, support the concept of a secret proprietary verification process, for handles they deem worthy of platform-wide public interest. In line with significant prior work which suggests that possessing ... ...

Abstract	Social network and publishing platforms, such as Twitter, support the concept of a secret proprietary verification process, for handles they deem worthy of platform-wide public interest. In line with significant prior work which suggests that possessing such a status symbolizes enhanced credibility in the eyes of the platform audience, a verified badge is clearly coveted among public figures and brands. What are less obvious are the inner workings of the verification process and what being verified represents. This lack of clarity, coupled with the flak that Twitter received by extending aforementioned status to political extremists in 2017, backed Twitter into publicly admitting that the process and what the status represented needed to be rethought. With this in mind, we seek to unravel the aspects of a user's profile which likely engender or preclude verification. The aim of the paper is two-fold: First, we test if discerning the verification status of a handle from profile metadata and content features is feasible. Second, we unravel the features which have the greatest bearing on a handle's verification status. We collected a dataset consisting of profile metadata of all 231,235 verified English-speaking users (as of July 2018), a control sample of 175,930 non-verified English-speaking users and all their 494 million tweets over a one year collection period. Our proposed models are able to reliably identify verification status (Area under curve AUC > 99%). We show that number of public list memberships, presence of neutral sentiment in tweets and an authoritative language style are the most pertinent predictors of verification status. To the best of our knowledge, this work represents the first attempt at discerning and classifying verification worthy users on Twitter.
Keywords	Computer Science - Social and Information Networks ; Computer Science - Computers and Society ; Computer Science - Machine Learning
Subject code	005
Publishing date	2019-03-12
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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