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  1. Article ; Online: Correction: Conserved amphipathic helices mediate lipid droplet targeting of perilipins 1-3.

    Rowe, Emily R / Mimmack, Michael L / Barbosa, Antonio D / Haider, Afreen / Isaac, Iona / Ouberai, Myriam M / Thiam, Abdou Rachid / Patel, Satish / Saudek, Vladimir / Siniossoglou, Symeon / Savage, David B

    The Journal of biological chemistry

    2021  Volume 298, Issue 1, Page(s) 101490

    Language English
    Publishing date 2021-12-20
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 2997-x
    ISSN 1083-351X ; 0021-9258
    ISSN (online) 1083-351X
    ISSN 0021-9258
    DOI 10.1016/j.jbc.2021.101490
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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.108: Show issues Location:
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  2. Article ; Online: Detection and genetic identification of

    Selmi, Rachid / Abdi, Khaoula / Belkahia, Hanène / Abdallah, Meriem Ben / Mamlouk, Aymen / Kratou, Myriam / Said, Mourad Ben / Messadi, Lilia

    Infectious medicine

    2024  Volume 3, Issue 1, Page(s) 100093

    Abstract: Background: Until now, there has been limited information on the prevalence and the phylogeny of : Methods: The present study aimed to determine the prevalence and the phylogeny of : Results: The study revealed a prevalence rate of 28% (28/100) ... ...

    Abstract Background: Until now, there has been limited information on the prevalence and the phylogeny of
    Methods: The present study aimed to determine the prevalence and the phylogeny of
    Results: The study revealed a prevalence rate of 28% (28/100) for
    Conclusion: These findings suggest the involvement of
    Language English
    Publishing date 2024-02-22
    Publishing country China
    Document type Journal Article
    ISSN 2772-431X
    ISSN (online) 2772-431X
    DOI 10.1016/j.imj.2024.100093
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  3. Article ; Online: Management of toxic cyanobacteria for drinking water production of Ain Zada Dam.

    Saoudi, Amel / Brient, Luc / Boucetta, Sabrine / Ouzrout, Rachid / Bormans, Myriam / Bensouilah, Mourad

    Environmental monitoring and assessment

    2017  Volume 189, Issue 7, Page(s) 361

    Abstract: ... in the treated water. On 11 May 2013, MC concentrations were 6.3 μg/L in MC-LR equivalent in the drinking water ...

    Abstract Blooms of toxic cyanobacteria in Algerian reservoirs represent a potential health problem, mainly from drinking water that supplies the local population of Ain Zada (Bordj Bou Arreridj). The objective of this study is to monitor, detect, and identify the existence of cyanobacteria and microcystins during blooming times. Samples were taken in 2013 from eight stations. The results show that three potentially toxic cyanobacterial genera with the species Planktothrix agardhii were dominant. Cyanobacterial biomass, phycocyanin (PC) concentrations, and microcystin (MC) concentrations were high in the surface layer and at 14 m depth; these values were also high in the treated water. On 11 May 2013, MC concentrations were 6.3 μg/L in MC-LR equivalent in the drinking water. This study shows for the first time the presence of cyanotoxins in raw and treated waters, highlighting that regular monitoring of cyanobacteria and cyanotoxins must be undertaken to avoid potential health problems.
    MeSH term(s) Biomass ; Cyanobacteria/classification ; Drinking Water/microbiology ; Environmental Monitoring ; Microcystins/analysis ; Water Purification/methods
    Chemical Substances Drinking Water ; Microcystins ; microcystin (77238-39-2) ; cyanoginosin LR (EQ8332842Y)
    Language English
    Publishing date 2017-07
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 782621-7
    ISSN 1573-2959 ; 0167-6369
    ISSN (online) 1573-2959
    ISSN 0167-6369
    DOI 10.1007/s10661-017-6058-4
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  4. Article: Fetal urine biochemistry in antenatal Bartter syndrome: a case report.

    Rachid, Myriam L / Dreux, Sophie / Czerkiewicz, Isabelle / Deschênes, Georges / Vargas-Poussou, Rosa / Mahieu-Caputo, Dominique / Oury, Jean-François / Muller, Françoise

    Clinical case reports

    2016  Volume 4, Issue 9, Page(s) 876–878

    Abstract: Bartter syndrome is a severe inherited tubulopathy responsible for renal salt wasting, and hence electrolyte disorders and dehydration. Prenatally, it is characterized by severe polyhydramnios caused by fetal polyuria. We studied for the first time fetal ...

    Abstract Bartter syndrome is a severe inherited tubulopathy responsible for renal salt wasting, and hence electrolyte disorders and dehydration. Prenatally, it is characterized by severe polyhydramnios caused by fetal polyuria. We studied for the first time fetal urine in a Bartter syndrome case and demonstrated that the tubulopathy is already present at 24 weeks of gestation.
    Language English
    Publishing date 2016-08-08
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.471
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Diversity and Phylogeny of Cattle Ixodid Ticks and Associated Spotted Fever Group

    Kratou, Myriam / Belkahia, Hanene / Selmi, Rachid / Andolsi, Rihab / Dhibi, Mokhtar / Mhadhbi, Moez / Messadi, Lilia / Ben Said, Mourad

    Pathogens (Basel, Switzerland)

    2023  Volume 12, Issue 4

    Abstract: Tick-borne rickettsioses are mainly caused by obligate intracellular bacteria belonging to the spotted fever group (SFG) of ... ...

    Abstract Tick-borne rickettsioses are mainly caused by obligate intracellular bacteria belonging to the spotted fever group (SFG) of the
    Language English
    Publishing date 2023-04-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens12040552
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  6. Article ; Online: Expanding the phenotype of GTF2E2-associated trichothiodystrophy.

    Sperelakis-Beedham, Brian / Ruaud, Lyse / Vial, Yoann / Rachid, Myriam / Ageorges, Faustine / Goujon, Louise / Verloes, Alain / Tabet, Anne-Claude / Bourrat, Emmanuelle / Lévy, Jonathan

    Journal of the European Academy of Dermatology and Venereology : JEADV

    2023  Volume 38, Issue 3, Page(s) e222–e226

    MeSH term(s) Humans ; Trichothiodystrophy Syndromes/diagnosis ; Trichothiodystrophy Syndromes/genetics ; Xeroderma Pigmentosum Group D Protein/genetics ; DNA Repair ; Phenotype
    Chemical Substances Xeroderma Pigmentosum Group D Protein (EC 3.6.4.12)
    Language English
    Publishing date 2023-10-16
    Publishing country England
    Document type Letter
    ZDB-ID 1128828-0
    ISSN 1468-3083 ; 0926-9959
    ISSN (online) 1468-3083
    ISSN 0926-9959
    DOI 10.1111/jdv.19545
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3492: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 413: Show issues

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  7. Article ; Online: Antimicrobial resistance levels among diarrhoeagenic micro-organisms recovered from children under-5 with acute moderate-to-severe diarrhoea in Rabat, Morocco.

    Benmessaoud, Rachid / Nezha, Mouane / Moraleda, Cinta / Jroundi, Imane / Tligui, Houssain / Seffar, Myriam / Pons, Maria J / Alvarez, Miriam J / Chaacho, Saad / Vila, Jordi / Alonso, Pedro L / Bassat, Quique / Ruiz, Joaquim

    Journal of global antimicrobial resistance

    2016  Volume 7, Page(s) 34–36

    MeSH term(s) Anti-Bacterial Agents ; Child, Preschool ; Diarrhea/microbiology ; Drug Resistance, Bacterial ; Feces ; Female ; Gastrointestinal Diseases/microbiology ; Humans ; Infant ; Male ; Morocco/epidemiology ; Prevalence
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2016-08-16
    Publishing country Netherlands
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 2710046-7
    ISSN 2213-7173 ; 2213-7165
    ISSN (online) 2213-7173
    ISSN 2213-7165
    DOI 10.1016/j.jgar.2016.07.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Prenatal diagnosis of Bartter syndrome: amniotic fluid aldosterone.

    Rachid, Myriam L / Dreux, Sophie / Pean de Ponfilly, Gauthier / Vargas-Poussou, Rosa / Czerkiewicz, Isabelle / Chevenne, Didier / Oury, Jean-François / Deschênes, Georges / Muller, Françoise

    Prenatal diagnosis

    2016  Volume 36, Issue 1, Page(s) 88–91

    Abstract: Objective: Bartter syndrome is a severe inherited tubulopathy characterized by postnatal salt wasting, severe polyuria, dehydration, failure to thrive and secondary hyperaldosteronism. Prenatally, the disease is usually discovered following the onset of ...

    Abstract Objective: Bartter syndrome is a severe inherited tubulopathy characterized by postnatal salt wasting, severe polyuria, dehydration, failure to thrive and secondary hyperaldosteronism. Prenatally, the disease is usually discovered following the onset of severe polyhydramnios in the second trimester. We studied amniotic fluid aldosterone concentration in Bartter syndrome and in controls.
    Methods: Amniotic fluid aldosterone was assayed by radioimmunoassay. We undertook a retrospective case-control study based on 36 cases of prenatally suspected and postnatally confirmed Bartter syndrome (22 with identified mutations): and 72 gestational age matched controls presenting with polyhydramnios and 72 without polyhydramnios. Amniotic fluid aldosterone was compared between the three groups.
    Results: The median amniotic fluid aldosterone concentration in the Bartter syndrome group (90 pg/mL) was not different from that in the controls with polyhydramnios (90 pg/mL, P = 0.33) or without polyhydramnios (87 pg/mL, P = 0.41).
    Conclusion: Amniotic fluid aldosterone assay cannot be used for prenatal diagnosis of Bartter syndrome. © 2015 John Wiley & Sons, Ltd.
    MeSH term(s) Aldosterone/metabolism ; Amniotic Fluid/metabolism ; Bartter Syndrome/diagnosis ; Bartter Syndrome/metabolism ; Biomarkers/metabolism ; Case-Control Studies ; Female ; Humans ; Pregnancy ; Pregnancy Trimester, Second ; Prenatal Diagnosis/methods ; Retrospective Studies
    Chemical Substances Biomarkers ; Aldosterone (4964P6T9RB)
    Language English
    Publishing date 2016-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 82031-3
    ISSN 1097-0223 ; 0197-3851
    ISSN (online) 1097-0223
    ISSN 0197-3851
    DOI 10.1002/pd.4717
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1625: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  9. Article ; Online: Conserved Amphipathic Helices Mediate Lipid Droplet Targeting of Perilipins 1-3.

    Rowe, Emily R / Mimmack, Michael L / Barbosa, Antonio D / Haider, Afreen / Isaac, Iona / Ouberai, Myriam M / Thiam, Abdou Rachid / Patel, Satish / Saudek, Vladimir / Siniossoglou, Symeon / Savage, David B

    The Journal of biological chemistry

    2016  Volume 291, Issue 13, Page(s) 6664–6678

    Abstract: Perilipins (PLINs) play a key role in energy storage by orchestrating the activity of lipases on the surface of lipid droplets. Failure of this activity results in severe metabolic disease in humans. Unlike all other lipid droplet-associated proteins, ... ...

    Abstract Perilipins (PLINs) play a key role in energy storage by orchestrating the activity of lipases on the surface of lipid droplets. Failure of this activity results in severe metabolic disease in humans. Unlike all other lipid droplet-associated proteins, PLINs localize almost exclusively to the phospholipid monolayer surrounding the droplet. To understand how they sense and associate with the unique topology of the droplet surface, we studied the localization of human PLINs inSaccharomyces cerevisiae,demonstrating that the targeting mechanism is highly conserved and that 11-mer repeat regions are sufficient for droplet targeting. Mutations designed to disrupt folding of this region into amphipathic helices (AHs) significantly decreased lipid droplet targetingin vivoandin vitro Finally, we demonstrated a substantial increase in the helicity of this region in the presence of detergent micelles, which was prevented by an AH-disrupting missense mutation. We conclude that highly conserved 11-mer repeat regions of PLINs target lipid droplets by folding into AHs on the droplet surface, thus enabling PLINs to regulate the interface between the hydrophobic lipid core and its surrounding hydrophilic environment.
    MeSH term(s) Amino Acid Sequence ; Animals ; Binding Sites ; Biological Transport ; COS Cells ; Carrier Proteins/chemistry ; Carrier Proteins/genetics ; Carrier Proteins/metabolism ; Chlorocebus aethiops ; Gene Expression ; Humans ; Hydrophobic and Hydrophilic Interactions ; Lipid Droplets/chemistry ; Lipid Droplets/metabolism ; Membrane Proteins/chemistry ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Micelles ; Models, Molecular ; Molecular Sequence Data ; Mutation ; Perilipin-1 ; Perilipin-2 ; Perilipin-3 ; Phosphoproteins/chemistry ; Phosphoproteins/genetics ; Phosphoproteins/metabolism ; Protein Binding ; Protein Interaction Domains and Motifs ; Protein Structure, Secondary ; Protein Transport ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae/ultrastructure ; Sequence Alignment ; Transgenes ; Vesicular Transport Proteins/chemistry ; Vesicular Transport Proteins/genetics ; Vesicular Transport Proteins/metabolism
    Chemical Substances Carrier Proteins ; Membrane Proteins ; Micelles ; PLIN3 protein, human ; Perilipin-1 ; Perilipin-2 ; Perilipin-3 ; Phosphoproteins ; Recombinant Proteins ; Vesicular Transport Proteins
    Language English
    Publishing date 2016-01-07
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2997-x
    ISSN 1083-351X ; 0021-9258
    ISSN (online) 1083-351X
    ISSN 0021-9258
    DOI 10.1074/jbc.M115.691048
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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.108: Show issues Location:
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  10. Article: Screening and Analysis of

    Belkahia, Hanène / Ben Abdallah, Meriem / Andolsi, Rihab / Selmi, Rachid / Zamiti, Sayed / Kratou, Myriam / Mhadhbi, Moez / Darghouth, Mohamed Aziz / Messadi, Lilia / Ben Said, Mourad

    Frontiers in veterinary science

    2021  Volume 8, Page(s) 731200

    Abstract: Bovine anaplasmosis caused ... ...

    Abstract Bovine anaplasmosis caused by
    Language English
    Publishing date 2021-10-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2834243-4
    ISSN 2297-1769
    ISSN 2297-1769
    DOI 10.3389/fvets.2021.731200
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