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Article ; Online: Unusual presentation of miliary tuberculosis in a 12-year-old girl: a case report.

Kamali, Mahsa / Navaeifar, Mohammad Reza / Abbaskhanian, Ali / Hajialibeig, Azin / Godazandeh, Farnaz / Salehpour, Mahsa / Rezai, Mohammad Sadegh

BMC pediatrics

2024 Volume 24, Issue 1, Page(s) 223

Abstract: Background: Miliary tuberculosis (TB) is a lethal hematogenous spread form of mycobacterium tuberculosis with approximately 15-20% mortality rate in children. The present report highlights the clinical manifestations of an unusual presentation of ... ...

Abstract	Background: Miliary tuberculosis (TB) is a lethal hematogenous spread form of mycobacterium tuberculosis with approximately 15-20% mortality rate in children. The present report highlights the clinical manifestations of an unusual presentation of miliary tuberculosis in a 12-year-old girl. Case presentation: In this case, extensive lung involvement was presented despite the absence of respiratory symptoms. Also, some central hypo-intense with hyper-intense rim nodules were detected in the brain's pons, right cerebral peduncles and lentiform nucleus. Conclusion: The results of this study showed that severe miliary TB may occur even in a person who received the Bacille Calmette-Guérin (BCG) vaccine.
MeSH term(s)	Child ; Female ; Humans ; Tuberculosis, Miliary/diagnosis ; Tuberculosis, Miliary/drug therapy ; BCG Vaccine ; Mycobacterium tuberculosis ; Pons
Chemical Substances	BCG Vaccine
Language	English
Publishing date	2024-04-01
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	2041342-7
ISSN	1471-2431 ; 1471-2431
ISSN (online)	1471-2431
ISSN	1471-2431
DOI	10.1186/s12887-023-04427-x
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Article: Developing a National Minimum Data Set for Kawasaki Disease Registry in Iran.

Qazizadeh, Zainab / Shahbaznejad, Leila / Navaeifar, Mohammad Reza / Rezai, Mohammad Sadegh

Frontiers in pediatrics

2022 Volume 10, Page(s) 834306

Abstract: Background: Kawasaki Disease is an acute and self-limited systemic inflammatory and febrile illness, which is the most common cause of acquired heart disease in children in developed countries. The incidence of KD in Asian countries is high. But, data ... ...

Abstract	Background: Kawasaki Disease is an acute and self-limited systemic inflammatory and febrile illness, which is the most common cause of acquired heart disease in children in developed countries. The incidence of KD in Asian countries is high. But, data is not available from the Middle East. So, the aim of this study was to develop an MDS to set up a national registry for KD to estimate the burden of disease in Iran. Materials and methods: This cross-sectional and descriptive study was conducted in 2020. Literature review, data collection from patients medical records, and expert panel approach were used to design this MDS. Data elements with a Content Validity Ratio (CVR) of more than 0.56 were selected as the MDS of the registry. Results: Overall, 99 data elements were recognized. Of which, 51 and 48 data elements were verified and rejected, respectively. Moreover, 17 data elements were added as required by experts. Eventually, 68 data elements were chosen as the MDS of the national KD registry of IRAN; of which, 17 and 51 data elements were classified as administrative and clinical data, respectively. Conclusions: These precise, integrated, and comprehensive developed data elements and the national KD registry will lead to effective disease management and thus, improve the quality of care and, consequently, improve public health.
Language	English
Publishing date	2022-02-28
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2711999-3
ISSN	2296-2360
ISSN	2296-2360
DOI	10.3389/fped.2022.834306
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Article: Compartment syndrome following snakebite in a boy: A case report and literature review.

Navaeifar, Mohammad Reza / Zakariaei, Zakaria / Ghadiri, Abolfazl / Soleymani, Mostafa / Zakariaei, Ashkan

International journal of surgery case reports

2023 Volume 105, Page(s) 108050

Abstract: Introduction and importance: Snake bites represent a significant public health issue worldwide, as venomous snake bites can result in lethal consequences if not treated promptly, including both local and systemic effects. The local symptoms of a snake ... ...

Abstract	Introduction and importance: Snake bites represent a significant public health issue worldwide, as venomous snake bites can result in lethal consequences if not treated promptly, including both local and systemic effects. The local symptoms of a snake bite commonly include tissue necrosis, edema, and compartment syndrome (CS). While CS is a rare complication following a snake bite, it may be more pronounced in children who typically have lower total dilution volume. Currently, the administration of anti-snake venom and prompt fasciotomy are the only specific treatments available for CS. Case presentation: The present report details a case of CS of the right upper extremity in a three-year-old boy who suffered a snake bite on his right hand and was brought to the emergency department of a hospital in northern Iran after a lapse of 14 h. Clinical discussion: Snakebites frequently occur in the extremities, with about two thirds of them happening in the upper extremities. The skin of the dorsum is extremely thin, there is essentially little subcutaneous fat tissue, and there are numerous superficial veins in this area, particularly the hand. Conclusions: Following snake bites, the use of proximal tourniquets should be avoided, and the public's awareness of this need should be encouraged through health education. The prognosis for recovery following fasciotomy and the significance of follow-up and rehabilitation should also be explained to patients.
Language	English
Publishing date	2023-03-24
Publishing country	Netherlands
Document type	Case Reports
ISSN	2210-2612
ISSN	2210-2612
DOI	10.1016/j.ijscr.2023.108050
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Article: COVID-19-Associated Multisystem Inflammatory Syndrome Complicated with Giant Coronary Artery Aneurysm.

Navaeifar, Mohammad Reza / Shahbaznejad, Leila / Sadeghi Lotfabadi, Ali / Rezai, Mohammad Sadegh

Case reports in pediatrics

2021 Volume 2021, Page(s) 8836403

Abstract: In the early stages of the outbreak of the novel coronavirus disease 2019 (COVID-19), it was assumed that this infection is very mild and uncommon in children. However, recent reports have shown that children may also develop the disease and its severe ... ...

Abstract	In the early stages of the outbreak of the novel coronavirus disease 2019 (COVID-19), it was assumed that this infection is very mild and uncommon in children. However, recent reports have shown that children may also develop the disease and its severe complications. These complications included shock, multisystem inflammatory syndrome in children (MIS-C), and pneumonia in children. A previously healthy 14-month-old boy presented with fever, irritability, and skin rash, besides changes in the lips, conjunctiva, and tongue. His medical history, clinical presentations, treatment, laboratory data, and follow-up information were recorded. He was treated according to the diagnosis of Kawasaki disease (KD). He had a history of close contact with a COVID-19 patient. However, the result of reverse transcription-polymerase chain reaction (RT-PCR) assay for COVID-19 was negative. Immunoglobulin M for COVID-19 was positive (1.20), while immunoglobulin G was negative (0.37). Three weeks later, seroconversion of COVID-19 immunoglobulin G (1.42) occurred. Despite treatment with two doses of intravenous immunoglobulin and methylprednisolone, coronary artery ectasia was detected. On the sixth day of hospitalization, the patient experienced hypotension, which necessitated treatment with inotropic drugs and resulted in a change of diagnosis to MIS-C. The later echocardiography showed evidence of coronary artery aneurysm (CAA), which finally changed to giant CAA. Although the patient was treated with infliximab, the size of CAA showed a significant decrease in the one-month follow-up. This is the first report of MIS-C during the COVID-19 pandemic in Iran, accompanied by KD, which was complicated with giant CAA.
Language	English
Publishing date	2021-01-06
Publishing country	United States
Document type	Case Reports
ZDB-ID	2659094-3
ISSN	2090-6811 ; 2090-6803
ISSN (online)	2090-6811
ISSN	2090-6803
DOI	10.1155/2021/8836403
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Article ; Online: Corrigendum to "Brown-Vialetto-Van Laere syndrome and Fazio-Londe syndrome: A novel mutation and in silico analyses" [J. Clin. Neurosci. 72 (2020) 342-349].

Rabbani, Bahareh / Bakhshandeh, Mohammad Kazem / Navaeifar, Mohammad Reza / Abbaskhanian, Ali / Soveizi, Mahdieh / Geravandpoor, Shahpour / Mahdieh, Nejat

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

2022 Volume 106, Page(s) 244

Language	English
Publishing date	2022-08-11
Publishing country	Scotland
Document type	Published Erratum
ZDB-ID	1193674-5
ISSN	1532-2653 ; 0967-5868
ISSN (online)	1532-2653
ISSN	0967-5868
DOI	10.1016/j.jocn.2022.07.026
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Article: Relation between Febrile Seizure Recurrence and Hyponatremia in Children: A Single-center Trial.

Navaeifar, Mohammad Reza / Abbaskhanian, Ali / Farmanbarborji, Akram

Journal of pediatric neurosciences

2020 Volume 15, Issue 1, Page(s) 5–8

Abstract: Background: Febrile seizure (FS) is one of the most common types of seizure in pediatrics.: Objective: The aim of this study was to compare serum sodium in children with simple or recurrent FS and seizure without fever.: Materials and methods: ... ...

Abstract	Background: Febrile seizure (FS) is one of the most common types of seizure in pediatrics. Objective: The aim of this study was to compare serum sodium in children with simple or recurrent FS and seizure without fever. Materials and methods: This was a cross-sectional prospective study conducted between September 2015 and April 2017 in patients aged between 6 months and 6 years, who were admitted to a tertiary educational medical center in the north of Iran. Patients were categorized into three groups, group A: simple FS, group B: recurrent FS, and group C: afebrile seizure. Serum sodium level was measured on admission and/or when the seizure occurred. Results: The study included 248 patients aged 6 months to 6 years. Their mean age was 22.38 ± 1.34 months. Hyponatremia was found in 6% of group A, 7.5% of group B, and 6% of group C. The mean sodium level in group A (134.46 ± 2.3 mEq/L) and group B (134.35 ± 2.06 mEq/L) did not disclose meaningful difference, but it was significantly lower in febrile groups than in the control group. Conclusion: Although the results did not show that the lower level of serum sodium increased the risk of seizure recurrence during the next 24h in febrile illness, lower serum sodium concentration was more common in FS groups.
Language	English
Publishing date	2020-02-18
Publishing country	India
Document type	Journal Article
ISSN	1817-1745
ISSN	1817-1745
DOI	10.4103/JPN.JPN_4_19
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Article: COVID-19 in Coincidence with Transient Distal Renal Tubular Acidosis in an Infant.

Razavi-Amoli, Seyedeh-Kiana / Mohammadjafari, Hamid / Zamanfar, Daniel / Navaeifar, Mohammad Reza / Sadati-Lamradi, Zahra / Rezai, Mohammad Sadegh

Case reports in infectious diseases

2022 Volume 2022, Page(s) 5361305

Abstract: Background: Post-COVID-19 nephropathies have been reported profusely in the literature with diverse pathophysiological mechanisms. To the best of our knowledge, this is the first report of transient distal (type 1) renal tubular acidosis (dRTA) in an ... ...

Abstract	Background: Post-COVID-19 nephropathies have been reported profusely in the literature with diverse pathophysiological mechanisms. To the best of our knowledge, this is the first report of transient distal (type 1) renal tubular acidosis (dRTA) in an infant with confirmed COVID-19. Conclusions: Regarding the various manifestations of COVID-19, the possible association between dRTA and COVID-19 needs further investigation in children.
Language	English
Publishing date	2022-05-27
Publishing country	Egypt
Document type	Case Reports
ZDB-ID	2627642-2
ISSN	2090-6633 ; 2090-6625
ISSN (online)	2090-6633
ISSN	2090-6625
DOI	10.1155/2022/5361305
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Article ; Online: Effective Dose of Radiation in Diagnostic and Interventional Cardiac Angiography among Pediatrics and Adolescents in Hospitals of Shiraz University of Medical Sciences versus Other Radiology Devices

Mohammad reza Edraki / Ehsan Karimi / Hamid Amoozgar / Mohammad reza Navaeifar

Iranian South Medical Journal, Vol 23, Iss 1, Pp 27-

2020 Volume 35

Abstract: Background: Cardiac catheterization and angiography are diagnostic and therapeutic imaging modalities that produce the highest X-ray radiation, which might impose lifelong risks to patients. This study aimed to evaluate radiation burden among children ... ...

Abstract	Background: Cardiac catheterization and angiography are diagnostic and therapeutic imaging modalities that produce the highest X-ray radiation, which might impose lifelong risks to patients. This study aimed to evaluate radiation burden among children and adolescents with congenital heart diseases, who underwent cardiac catheterization and angiography. Then the results were compared with other imaging modalities. Materials and Methods: In this prospective study, children and adolescents with congenital heart diseases were consecutively evaluated from April 2017 till November 2017. This research was designed in Namazi and Faghihi teaching hospitals affiliated to Shiraz University of Medical Sciences, Shiraz, Iran. In addition to the basic data and total radiation time, effective dose and dose area product were assessed for each patient. Results: We enrolled 148 consecutive patients under 18 years old, who underwent 36 diagnostic and 112 interventional cardiac catheterizations. Effective dose was 50.23 mGy in the diagnostic catheterizations, and 48.39 mGy in the interventional angiographies. Also the dose area product was 427/28 mGy.cm2 in the diagnostic catheterizations, and 476.62 mGy.cm2 in the interventional angiography. The most time-consuming cine fluoroscopy pertained to ventricular septal defect closure and (11.67 seconds) and the most effective dose and dose area product pertained to the same procedure, as well (68,514 mGy and 623,843 mGy.cm2 respectively). Conclusion: Effective dose and dose area product in cardiac catheterization were desirable, and some previous studies revealed that carcinogenic effect of X-ray radiation is more prominent when effective dose is more than 70-100 mGy. Thus the effective dose might not cause hazardous outcomes if other x ray modalities are not frequently requested for them in future.
Keywords	cardiac angiography ; pediatrics ; fluoroscopy ; effective dose ; radiation ; Medicine (General) ; R5-920
Subject code	610
Language	English
Publishing date	2020-03-01T00:00:00Z
Publisher	Bushehr University of Medical Sciences
Document type	Article ; Online
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Article: Clinical Characteristics and Outcomes of COVID-19 in Children in Northern Iran.

Shahbaznejad, Leila / Rouhanizadeh, Hamed / Navaeifar, Mohammad Reza / Hosseinzadeh, Fatemeh / Movahedi, Faeze Sadat / Rezai, Mohammad Sadegh

International journal of pediatrics

2021 Volume 2021, Page(s) 5558287

Abstract: Objective: Since December 2019, the coronavirus disease 2019 (COVID-19) has been spread rapidly all over the world, infecting all age groups with this novel virus. In this manuscript, we report characteristics of children with COVID-19 in Mazandaran ... ...

Abstract	Objective: Since December 2019, the coronavirus disease 2019 (COVID-19) has been spread rapidly all over the world, infecting all age groups with this novel virus. In this manuscript, we report characteristics of children with COVID-19 in Mazandaran province, northern Iran. Method: From 12 February to 28 July 2020, medical records of 100 children diagnosed with COVID-19 admitted to the hospitals of Mazandaran province were collected. Patients' age, gender, clinical symptoms, and signs, in addition to therapeutic management and outcomes, were reported. Results: 57 (57%) boys and 43 girls with the mean age of 104.63 ± 79.14 months were evaluated. 20 patients (20%) were transferred to the PICU (pediatric intensive care unit), and 13 children experienced a severe form of the disease, pediatric inflammatory multisystem syndrome (PIMS). The mean duration of hospitalization was 5.3 ± 4.7 days. Fever (81%), respiratory (79%), gastrointestinal (47%), and neurologic complaints (29%) were experienced by the patients in addition to skin rash (14%). Sixty-two patients needed supplemental oxygen, and 6 of them underwent endotracheal intubation. Leukopenia was reported in 7, anemia in 24, and thrombocytopenia in 12 patients. 4 patients with underlying diseases including chronic renal failure, Down syndrome with cerebral palsy, and morbid obesity died. Conclusion: COVID-19 can cause symptoms in children in two stages. In the first week, upper and lower respiratory symptoms can occur which has lower severity and prevalence compared to adults. But after 2-3 weeks following infection, symptoms of MIS-C or multisystem involvement can occur and COVID-19 should be considered. The most common indication for admission is fever, rash, and respiratory problems.
Language	English
Publishing date	2021-04-28
Publishing country	Egypt
Document type	Journal Article
ZDB-ID	2495026-9
ISSN	1687-9759 ; 1687-9740
ISSN (online)	1687-9759
ISSN	1687-9740
DOI	10.1155/2021/5558287
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Article ; Online: Response to Letter Regarding Article, "Effects of Ivermectin in Patients With COVID-19: A Multicenter, Double-Blind, Randomized, Controlled Clinical Trial".

Shahbaznejad, Leila / Davoudi, Alireza / Eslami, Gohar / Markowitz, John S / Navaeifar, Mohammad Reza / Hosseinzadeh, Fatemeh / Movahedi, Faeze Sadat / Rezai, Mohammad Sadegh

Clinical therapeutics

2021 Volume 43, Issue 9, Page(s) 1624–1626

MeSH term(s)	COVID-19 ; Double-Blind Method ; Humans ; Ivermectin ; SARS-CoV-2 ; Treatment Outcome
Chemical Substances	Ivermectin (70288-86-7)
Language	English
Publishing date	2021-08-05
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	603113-4
ISSN	1879-114X ; 0149-2918
ISSN (online)	1879-114X
ISSN	0149-2918
DOI	10.1016/j.clinthera.2021.07.006
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Zs.A 1435: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 404: Show issues

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