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  1. Article ; Online: Could Phosphate Provide a Second Chance for Statin Therapy in Kidney Failure?

    Gutiérrez, Orlando M

    Clinical journal of the American Society of Nephrology : CJASN

    2022  Volume 17, Issue 4, Page(s) 478–480

    MeSH term(s) Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects ; Phosphates ; Renal Insufficiency ; Renal Insufficiency, Chronic ; Risk Factors
    Chemical Substances Hydroxymethylglutaryl-CoA Reductase Inhibitors ; Phosphates
    Language English
    Publishing date 2022-03-02
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural
    ZDB-ID 2226665-3
    ISSN 1555-905X ; 1555-9041
    ISSN (online) 1555-905X
    ISSN 1555-9041
    DOI 10.2215/CJN.02210222
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6584: Show issues Location:
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  2. Article ; Online: Treatment of Iron Deficiency Anemia in CKD and End-Stage Kidney Disease.

    Gutiérrez, Orlando M

    Kidney international reports

    2021  Volume 6, Issue 9, Page(s) 2261–2269

    Abstract: Iron deficiency is common in individuals with chronic kidney disease and plays a major role in the development of anemia. Oral and intravenous iron agents are both available to replete iron in patients with chronic kidney disease diagnosed with iron ... ...

    Abstract Iron deficiency is common in individuals with chronic kidney disease and plays a major role in the development of anemia. Oral and intravenous iron agents are both available to replete iron in patients with chronic kidney disease diagnosed with iron deficiency. The choice of which agent to use is most often dictated by goals of therapy, tolerability, convenience, and response to prior therapy. Diminished absorption of iron in the gastrointestinal tract and a high incidence of gastrointestinal adverse effects can reduce the efficacy of oral iron agents, necessitating the use of i.v. iron formulations to treat iron deficiency anemia, particularly in patients requiring kidney replacement therapy. Newer oral agents may help to overcome these limitations and help treat iron deficiency in those not requiring kidney replacement therapy. Recent studies have provided new evidence that more aggressive repletion of iron in patients with chronic kidney disease requiring kidney replacement therapy may provide benefits with respect to anemia management and hard clinical outcomes such as cardiovascular disease and survival.
    Language English
    Publishing date 2021-06-05
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2468-0249
    ISSN (online) 2468-0249
    DOI 10.1016/j.ekir.2021.05.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Recent Advances in the Role of Diet in Bone and Mineral Disorders in Chronic Kidney Disease.

    Gutiérrez, Orlando M

    Current osteoporosis reports

    2021  Volume 19, Issue 6, Page(s) 574–579

    Abstract: Purpose of review: Chronic kidney disease mineral and bone disease (CKD-MBD) is a common complication of kidney disease and is strongly influenced by diet. The purpose of this manuscript is to review recent advances in the role of diet in CKD-MBD over ... ...

    Abstract Purpose of review: Chronic kidney disease mineral and bone disease (CKD-MBD) is a common complication of kidney disease and is strongly influenced by diet. The purpose of this manuscript is to review recent advances in the role of diet in CKD-MBD over the last 5 years.
    Recent findings: Many of the recent studies examining the role of diet in CKD-MBD have focused on the adverse effects of high phosphorus consumption on bone health and metabolism. In general, the studies have shown that high phosphorus consumption worsens markers of bone and mineral metabolism but that eating a diet with a calcium to phosphorus ratio closer to 1:1 can attenuate some of these effects. Recent studies also showed that dietary counseling is efficacious for improving markers of CKD-MBD. High consumption of phosphorus aggravates CKD-MBD. Dietary counseling may ameliorate these effects, for example, by consuming diets with higher calcium to phosphorus ratios.
    MeSH term(s) Chronic Kidney Disease-Mineral and Bone Disorder/diet therapy ; Humans
    Language English
    Publishing date 2021-11-03
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 2186581-4
    ISSN 1544-2241 ; 1544-1873
    ISSN (online) 1544-2241
    ISSN 1544-1873
    DOI 10.1007/s11914-021-00710-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Fibroblast Growth Factor 23 and the Last Mile.

    Gutiérrez, Orlando M

    Clinical journal of the American Society of Nephrology : CJASN

    2020  Volume 15, Issue 9, Page(s) 1355–1357

    MeSH term(s) Animals ; Biomarkers/blood ; Chronic Kidney Disease-Mineral and Bone Disorder/blood ; Chronic Kidney Disease-Mineral and Bone Disorder/diagnosis ; Chronic Kidney Disease-Mineral and Bone Disorder/drug therapy ; Chronic Kidney Disease-Mineral and Bone Disorder/physiopathology ; Fibroblast Growth Factor-23/blood ; Humans ; Hyperparathyroidism, Secondary/blood ; Hyperparathyroidism, Secondary/diagnosis ; Hyperparathyroidism, Secondary/drug therapy ; Hyperparathyroidism, Secondary/physiopathology ; Kidney/drug effects ; Kidney/metabolism ; Kidney/physiopathology ; Phosphorus/blood ; Renal Agents/therapeutic use ; Renal Insufficiency, Chronic/blood ; Renal Insufficiency, Chronic/diagnosis ; Renal Insufficiency, Chronic/drug therapy ; Renal Insufficiency, Chronic/physiopathology ; Vitamin D/analogs & derivatives ; Vitamin D/blood
    Chemical Substances Biomarkers ; FGF23 protein, human ; Renal Agents ; Vitamin D (1406-16-2) ; Phosphorus (27YLU75U4W) ; 1,25-dihydroxyvitamin D (66772-14-3) ; Fibroblast Growth Factor-23 (7Q7P4S7RRE)
    Language English
    Publishing date 2020-04-10
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2226665-3
    ISSN 1555-905X ; 1555-9041
    ISSN (online) 1555-905X
    ISSN 1555-9041
    DOI 10.2215/CJN.13631119
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Risks of anticoagulation in patients with chronic kidney disease and atrial fibrillation: More than just bleeding?

    Gutiérrez, Orlando M

    Research and practice in thrombosis and haemostasis

    2019  Volume 3, Issue 2, Page(s) 147–148

    Language English
    Publishing date 2019-03-05
    Publishing country United States
    Document type Journal Article
    ISSN 2475-0379
    ISSN (online) 2475-0379
    DOI 10.1002/rth2.12188
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  6. Article ; Online: Connecting the dots on fibroblast growth factor 23 and left ventricular hypertrophy.

    Gutiérrez, Orlando M

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    2016  Volume 31, Issue 7, Page(s) 1031–1033

    Language English
    Publishing date 2016-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 90594-x
    ISSN 1460-2385 ; 0931-0509
    ISSN (online) 1460-2385
    ISSN 0931-0509
    DOI 10.1093/ndt/gfv445
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2198: Show issues Location:
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    Zs.MO 329: Show issues

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  7. Article ; Online: Fibroblast growth factor 23 and heart failure: the plot thickens.

    Gutiérrez, Orlando M

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    2016  Volume 31, Issue 5, Page(s) 688–690

    Language English
    Publishing date 2016-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 90594-x
    ISSN 1460-2385 ; 0931-0509
    ISSN (online) 1460-2385
    ISSN 0931-0509
    DOI 10.1093/ndt/gfv401
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 329: Show issues

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  8. Article ; Online: Transplant Nephrology.

    Chonchol, Michel / Gutierrez, Orlando M / Rahman, Mahboob / Charytan, David M / Rosner, Mitchell

    Clinical journal of the American Society of Nephrology : CJASN

    2022  Volume 17, Issue 9, Page(s) 1272–1274

    MeSH term(s) Humans ; Nephrology ; Kidney Transplantation
    Language English
    Publishing date 2022-08-01
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2226665-3
    ISSN 1555-905X ; 1555-9041
    ISSN (online) 1555-905X
    ISSN 1555-9041
    DOI 10.2215/CJN.08710722
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6584: Show issues Location:
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  9. Article ; Online: Response to letter regarding article, "fibroblast growth factor 23 and risk of incident stroke in community-living adults".

    Gutiérrez, Orlando M

    Stroke

    2015  Volume 46, Issue 5, Page(s) e124

    MeSH term(s) Female ; Fibroblast Growth Factors/blood ; Humans ; Male ; Population Surveillance ; Stroke/blood ; Stroke/epidemiology
    Chemical Substances Fibroblast Growth Factors (62031-54-3)
    Language English
    Publishing date 2015-05
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.115.008910
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 448: Show issues Location:
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  10. Article ; Online: Associations of FGF23 with 10-Year Change in eGFR and UACR and with Incident CKD in the CARDIA Cohort.

    Sunderraj, Ashwin / Wong, Mandy / Gutiérrez, Orlando M / Wolf, Myles / Akhabue, Ehimare / Carnethon, Mercedes R / Yancy, Clyde W / Isakova, Tamara

    Kidney360

    2023  Volume 4, Issue 9, Page(s) e1236–e1244

    MeSH term(s) Humans ; Renal Insufficiency, Chronic/epidemiology ; Renal Insufficiency, Chronic/complications ; Risk Factors
    Language English
    Publishing date 2023-06-02
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ISSN 2641-7650
    ISSN (online) 2641-7650
    DOI 10.34067/KID.0000000000000172
    Database MEDical Literature Analysis and Retrieval System OnLINE

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