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  1. Article: Editorial: Pulmonary fibrosis and lung carcinogenesis: do myofibroblasts and cancer-associated fibroblasts share a common identity?

    de Totero, Daniela / Barisione, Emanuela / Clini, Enrico

    Frontiers in oncology

    2024  Volume 14, Page(s) 1389532

    Language English
    Publishing date 2024-03-11
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2024.1389532
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  2. Article ; Online: Blood clot 'coral' of the tracheobronchial tree.

    Barisione, Emanuela / Robba, Chiara / Tagliabue, Elena / Pelosi, Paolo

    BMJ case reports

    2021  Volume 14, Issue 6

    MeSH term(s) Animals ; Anthozoa ; Bronchi/diagnostic imaging ; Humans ; Respiration, Artificial ; Thrombosis ; Trachea/diagnostic imaging
    Language English
    Publishing date 2021-06-29
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2021-242533
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  3. Article ; Online: Primary endobronchial melanoma: a case report and clinical management indications.

    Barisione, Emanuela / Boutros, Andrea / Mora, Marco / Spagnolo, Francesco / Tanda, Enrica Teresa / Genova, Carlo / Tagliabue, Elena

    BMC pulmonary medicine

    2024  Volume 24, Issue 1, Page(s) 97

    Abstract: Background: While cutaneous melanomas are well-documented, primary melanoma of the lung (PMML), particularly with endobronchial origin, remains rare and poorly characterized. This case report addresses gaps in understanding by presenting a comprehensive ...

    Abstract Background: While cutaneous melanomas are well-documented, primary melanoma of the lung (PMML), particularly with endobronchial origin, remains rare and poorly characterized. This case report addresses gaps in understanding by presenting a comprehensive case of a 71-year-old male with primary endobronchial melanoma and conducting a systematic review of PMML cases.
    Case presentation: The patient, a former smoker, presented with dyspnea, cough, and hemoptysis. Imaging revealed left lung atelectasis and a suspicious nodule. Bronchoscopy identified an endobronchial mass, subsequently treated with argon plasma coagulation and resection. Biopsy confirmed melanoma. Extensive examinations ruled out a primary skin lesion. Despite initial treatment, recurrence led to pneumonectomy. Histopathology confirmed melanoma. The patient received treatment with pembrolizumab and ipilimumab, but with poor clinical benefit.
    Conclusions: Primary endobronchial melanoma is a rare entity, comprising 0.01% of lung tumors. This case underscores diagnostic challenges and emphasizes histological criteria to distinguish primary from metastatic lesions. The pathogenesis remains unclear, with theories proposing foetal melanocyte migration or squamous metaplasia. Prognosis varies, necessitating radical surgical extirpation. A systematic review revealed diverse outcomes, supporting the need for further research. In conclusion, endobronchial melanoma involves an endoscopic and surgical management, but evolving therapies, such as immunotherapy, may reshape treatment paradigms. This case contributes to our understanding of PMML, guiding future research and clinical management. As therapeutic options evolve, continued research is crucial to refine our understanding and improve outcomes for this rare malignancy.
    MeSH term(s) Male ; Humans ; Aged ; Melanoma/diagnosis ; Melanoma/therapy ; Melanoma/pathology ; Skin Neoplasms/pathology ; Lung Neoplasms/diagnosis ; Lung Neoplasms/therapy ; Lung Neoplasms/pathology ; Lung/pathology ; Biopsy
    Language English
    Publishing date 2024-02-24
    Publishing country England
    Document type Systematic Review ; Case Reports ; Journal Article
    ZDB-ID 2059871-3
    ISSN 1471-2466 ; 1471-2466
    ISSN (online) 1471-2466
    ISSN 1471-2466
    DOI 10.1186/s12890-024-02904-2
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  4. Article ; Online: Pulmonary hypertension in systemic sclerosis with usual interstitial pneumonia.

    Carbone, Roberto G / Monselise, Assaf / Barisione, Emanuela / Fontana, Vincenzo / Paredi, Paolo / Puppo, Francesco

    Internal and emergency medicine

    2023  Volume 18, Issue 4, Page(s) 1087–1093

    Abstract: Retrospective study comparing pulmonary hypertension risk in systemic sclerosis (SSc) and non-SSc interstitial lung disease patients with usual interstitial pneumonia (UIP) and non-specific interstitial pneumonia (NSIP). Retrospective analysis of 144 ... ...

    Abstract Retrospective study comparing pulmonary hypertension risk in systemic sclerosis (SSc) and non-SSc interstitial lung disease patients with usual interstitial pneumonia (UIP) and non-specific interstitial pneumonia (NSIP). Retrospective analysis of 144 interstitial lung disease patients, 53 SSc (32 UIP and 21 NSIP) and 91 non-SSc (47 UIP and 44 NSIP). Pulmonary hypertension was diagnosed as pulmonary systolic artery pressure (PAPs) > 25 mmHg. All SSc and non-SSc patients with pulmonary hypertension were classified WHO Group 3. Pulmonary hypertension was identified in 21/32 (65.6%), 9/21 (42.8%), 14/47 (29.7%), and 28/44 (45.4%) SSc-UIP, SSc-NSIP, control-UIP, and control-NSIP groups, respectively. PAPs mean of SSc-UIP group was higher than control-UIP group (32.6 ± 9.8 vs 28.5 ± 6.6, p-value = 0.02). PAPs mean of SSc-NSIP group was lower than control-NSIP group (27.0 ± 7.1 vs 33.9 ± 8.8, p = 0.002). Frequency of patients with PAP > 25 mmHg in SSc-UIP group was 60% higher in comparison to control-UIP (OR = 1.62, 95% CI 0.51-5.16) and SSc-NSIP (OR = 1.60, 95% CI 0.45-5.70) groups. Logistic regression analysis estimating the linear trend per ten-unit increase in PAPs levels demonstrated an increment for the SSc-UIP group compared to the control-UIP (OR = 2.64, 95% CI 1.25-5.58, p = 0.01) and the control-NSIP (OR = 6.34, 95% CI 2.82-14.3, p < 0.001) groups. The case-control study confirms that pulmonary hypertension is frequently found in SSc patients and demonstrates, for the first time, a significant increased risk of pulmonary hypertension among SSc-UIP patients.
    MeSH term(s) Humans ; Retrospective Studies ; Hypertension, Pulmonary/epidemiology ; Hypertension, Pulmonary/etiology ; Case-Control Studies ; Idiopathic Pulmonary Fibrosis ; Lung Diseases, Interstitial/complications ; Lung Diseases, Interstitial/epidemiology ; Lung ; Scleroderma, Systemic/complications
    Language English
    Publishing date 2023-04-17
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2454173-4
    ISSN 1970-9366 ; 1828-0447
    ISSN (online) 1970-9366
    ISSN 1828-0447
    DOI 10.1007/s11739-023-03267-y
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  5. Article ; Online: Lung fibrosis: an undervalued finding in COVID-19 pathological series.

    Grillo, Federica / Barisione, Emanuela / Ball, Lorenzo / Mastracci, Luca / Fiocca, Roberto

    The Lancet. Infectious diseases

    2020  Volume 21, Issue 4, Page(s) e72

    MeSH term(s) Autopsy ; COVID-19 ; Humans ; Italy ; Pulmonary Fibrosis ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-28
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(20)30582-X
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    Zs.A 5743: Show issues Location:
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  6. Article ; Online: Response to the letter of Gemignani et al.

    Grisanti, Stefano Giuseppe / Bellucci, Margherita / Germano, Francesco / Schenone, Cristina / Barisione, Emanuela / Garbarino, Sara / Piana, Michele / Pardini, Matteo / Benedetti, Luana

    Journal of the neurological sciences

    2022  Volume 444, Page(s) 120491

    Language English
    Publishing date 2022-11-24
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 80160-4
    ISSN 1878-5883 ; 0022-510X ; 0374-8642
    ISSN (online) 1878-5883
    ISSN 0022-510X ; 0374-8642
    DOI 10.1016/j.jns.2022.120491
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    Zs.A 308: Show issues Location:
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  7. Article ; Online: Beyond Covid-19 vaccination-associated pitfalls on [

    Bauckneht, Matteo / Aloè, Teresita / Tagliabue, Elena / Cittadini, Giuseppe / Guadagno, Antonio / Morbelli, Silvia / Barisione, Emanuela

    European journal of nuclear medicine and molecular imaging

    2021  Volume 48, Issue 8, Page(s) 2661–2662

    MeSH term(s) COVID-19 ; COVID-19 Vaccines ; Fluorodeoxyglucose F18 ; Humans ; Positron-Emission Tomography ; Radiopharmaceuticals ; SARS-CoV-2 ; Sarcoidosis/diagnostic imaging ; Vaccination
    Chemical Substances COVID-19 Vaccines ; Radiopharmaceuticals ; Fluorodeoxyglucose F18 (0Z5B2CJX4D)
    Language English
    Publishing date 2021-04-20
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 8236-3
    ISSN 1619-7089 ; 0340-6997 ; 1619-7070
    ISSN (online) 1619-7089
    ISSN 0340-6997 ; 1619-7070
    DOI 10.1007/s00259-021-05360-w
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    Zs.A 1227: Show issues Location:
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  8. Article ; Online: High prevalence of olfactory and taste disorder during SARS-CoV-2 infection in outpatients.

    De Maria, Andrea / Varese, Paola / Dentone, Chiara / Barisione, Emanuela / Bassetti, Matteo

    Journal of medical virology

    2020  Volume 92, Issue 11, Page(s) 2310–2311

    MeSH term(s) COVID-19 ; Humans ; Outpatients ; Pandemics ; Prevalence ; SARS-CoV-2 ; Taste Disorders/epidemiology
    Keywords covid19
    Language English
    Publishing date 2020-05-17
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.25995
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    Zs.A 1320: Show issues Location:
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  9. Article: A lymph node mediastinal foreign body reaction mimicking nodal metastasis: A case series.

    Zuccatosta, Lina / Latini, Maria Agnese / Mei, Federico / Bonifazi, Martina / Barisione, Emanuela / Salio, Mario / Gasparini, Stefano / Gonnelli, Francesca

    Frontiers in medicine

    2022  Volume 9, Page(s) 1014617

    Abstract: Introduction: In the last decades, many haemostatic substances included oxidized cellulose topically applied have been used during surgery and their use have become a common practice. Oxidized cellulose (OC) is one of the most used haemostatic ... ...

    Abstract Introduction: In the last decades, many haemostatic substances included oxidized cellulose topically applied have been used during surgery and their use have become a common practice. Oxidized cellulose (OC) is one of the most used haemostatic substances. However, different studies have shown the persistence of OC deposits after surgical procedures that may simulate recurrent malignancies and abscesses. We present a case series of patients with enlarged on CT and PET-FDG positive lymphadenopathies due to foreign body inflammatory reaction to OC after lung surgery for pulmonary malignancies.
    Methods: Retrospective chart review of patients from 2021 to 2022 who underwent EBUS-TBNA for the characterization of hilar and/or mediastinal lymphadenopathies and a histopathological diagnosis of foreign body inflammatory reaction to OC.
    Results: Eight
    Conclusion: In patients who underwent surgery for lung cancer, especially within few months, the development of lymph node foreign body reaction due to surgical material retention should always be considered.
    Language English
    Publishing date 2022-09-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2022.1014617
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  10. Article: Pneumomediastinum after transbronchial cryobiopsy.

    Barisione, Emanuela / Bianchi, Rita / Fiocca, Roberto / Salio, Mario

    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace

    2018  Volume 88, Issue 2, Page(s) 909

    Abstract: Pneumomediastinum is defined as the presence of air or gas within the mediastinum and it rarely complicates bronchoscopy. We report, to our best knowledge, the first case of pneumomediastinum following a transbronchial cryobiopsy (TBLC). TBLC is ... ...

    Abstract Pneumomediastinum is defined as the presence of air or gas within the mediastinum and it rarely complicates bronchoscopy. We report, to our best knowledge, the first case of pneumomediastinum following a transbronchial cryobiopsy (TBLC). TBLC is considered a safe procedure as compared with both transbronchial biopsy and surgical lung biopsy. Systematic reviews, metanalysis and a Pubmed research, revealed that in literature no pneumomediastinum has been mentioned after TBLC. We report this case for to make it known to interventional pulmonologists the possibility that a pneumomediastinum can follow a TBLC. In our case the spontaneous resolution in few days did not require any intervention.
    Language English
    Publishing date 2018-06-22
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 1160940-0
    ISSN 1122-0643 ; 1120-0391
    ISSN 1122-0643 ; 1120-0391
    DOI 10.4081/monaldi.2018.909
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