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Article ; Online: Pneumococcal induced thrombotic thrombocytopenic purpura with features of purpura fulminans.

Walsh, Laura Frances / Sherbuk, Jacqueline E / Wispelwey, Brian

BMJ case reports

2021 Volume 14, Issue 1

Abstract: A 42-year-old woman with a history of acute myeloid leukaemia status postallogeneic stem cell transplant presented with fevers, altered mental status, pulmonary infiltrates and septic shock that further progressed to thrombocytopenia and purpura ... ...

Abstract	A 42-year-old woman with a history of acute myeloid leukaemia status postallogeneic stem cell transplant presented with fevers, altered mental status, pulmonary infiltrates and septic shock that further progressed to thrombocytopenia and purpura fulminans. Laboratory studies were consistent with a diagnosis of thrombotic thrombocytopenic purpura (TTP). Blood cultures grew
MeSH term(s)	Adult ; Anti-Bacterial Agents/therapeutic use ; Bacteremia/blood ; Bacteremia/complications ; Bacteremia/therapy ; Ceftriaxone/therapeutic use ; Diagnosis, Differential ; Female ; Fibrinolytic Agents/therapeutic use ; Fingers/pathology ; Fingers/surgery ; Gangrene ; Glucocorticoids/therapeutic use ; Graft vs Host Disease/drug therapy ; Humans ; Immunologic Factors/therapeutic use ; Leukemia, Myeloid, Acute/therapy ; Nose/pathology ; Plasma Exchange ; Pneumococcal Infections/blood ; Pneumococcal Infections/complications ; Pneumococcal Infections/therapy ; Purpura Fulminans/blood ; Purpura Fulminans/diagnosis ; Purpura, Thrombotic Thrombocytopenic/blood ; Purpura, Thrombotic Thrombocytopenic/etiology ; Purpura, Thrombotic Thrombocytopenic/therapy ; Rituximab/therapeutic use ; Shock, Septic/blood ; Shock, Septic/complications ; Shock, Septic/therapy ; Single-Domain Antibodies/therapeutic use ; Stem Cell Transplantation ; Toes/pathology ; Toes/surgery
Chemical Substances	Anti-Bacterial Agents ; Fibrinolytic Agents ; Glucocorticoids ; Immunologic Factors ; Single-Domain Antibodies ; caplacizumab (2R27AB6766) ; Rituximab (4F4X42SYQ6) ; Ceftriaxone (75J73V1629)
Language	English
Publishing date	2021-01-26
Publishing country	England
Document type	Case Reports ; Journal Article
ISSN	1757-790X
ISSN (online)	1757-790X
DOI	10.1136/bcr-2020-235580
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Training the next generation of HIV providers: impact of trainees on patient satisfaction in an urban HIV clinic.

Sherbuk, Jacqueline E / Barakat, Lydia Aoun

AIDS care

2018 Volume 31, Issue 1, Page(s) 41–44

Abstract: For persons living with HIV and AIDS (PLWHA), care by an HIV-specialist improves outcomes and satisfaction with one's HIV primary care provider (PCP) promotes engagement with care. In the United States, we are facing a workforce shortage of HIV providers. ...

Abstract	For persons living with HIV and AIDS (PLWHA), care by an HIV-specialist improves outcomes and satisfaction with one's HIV primary care provider (PCP) promotes engagement with care. In the United States, we are facing a workforce shortage of HIV providers. As we aim to train a new generation of HIV providers, it is unclear how PLWHA perceive their experience when cared for by trainees compared to experienced providers. Therefore we assessed patient satisfaction with HIV providers, both trainees in an HIV Primary Care residency program and HIV-specialists. A secondary objective was to evaluate providers' performance in adhering to standard management guidelines for HIV-associated and non-HIV-associated conditions. We surveyed 75 PLWHA, including 51 (68%) assigned to an HIV-specialist PCP and 24 (32%) to a trainee PCP. Overall patient satisfaction on a 10-point scale was similar (mean 9.6 HIV-specialist vs 9.7 trainee, p = 0.71) and remained similar in multivariate logistic regression analysis when controlling for patient age, gender, race, and recently establishing care (Odds Ratio 1.1, 95% Confidence Interval 0.3-5.0). Participants in the trainee group were more likely to feel their provider "always" spent enough time with them (100% vs 81%, p = 0.03). Adherence to HIV guidelines was similar, though trainees were more likely to document counseling on risk reduction (83% vs 47%, p = 0.005) and adherence to antiretroviral therapy (100% vs 66%, p = 0.001). In conclusion, in a structured HIV-training program, residents can provide subspecialty level care in an HIV continuity clinic with levels of performance and patient satisfaction equivalent to those of experienced specialists.
MeSH term(s)	Adult ; Ambulatory Care Facilities ; Capacity Building ; Connecticut ; Counseling ; Female ; HIV Infections/psychology ; HIV Infections/therapy ; Health Occupations/education ; Health Workforce/statistics & numerical data ; Humans ; Internship and Residency ; Male ; Middle Aged ; Patient Satisfaction ; Physicians ; Physicians, Primary Care/education ; Primary Health Care/organization & administration ; Surveys and Questionnaires ; United States
Language	English
Publishing date	2018-05-21
Publishing country	England
Document type	Journal Article
ZDB-ID	1012651-x
ISSN	1360-0451 ; 0954-0121
ISSN (online)	1360-0451
ISSN	0954-0121
DOI	10.1080/09540121.2018.1476663
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Article: Financial, Food, and Housing Insecurity Due to Coronavirus Disease 2019 Among At-Risk People With Human Immunodeficiency Virus in a Nonurban Ryan White HIV/AIDS Program Clinic.

Sherbuk, Jacqueline E / Williams, Brooke / McManus, Kathleen A / Dillingham, Rebecca

Open forum infectious diseases

2020 Volume 7, Issue 10, Page(s) ofaa423

Abstract: Coronavirus disease 2019 negatively impacts social determinants of health that contribute to disparities for people with human immunodeficiency virus (HIV). Insecurity of food, housing, and employment increased significantly in April 2020 among patients ... ...

Abstract	Coronavirus disease 2019 negatively impacts social determinants of health that contribute to disparities for people with human immunodeficiency virus (HIV). Insecurity of food, housing, and employment increased significantly in April 2020 among patients with lower incomes at a Ryan White HIV/AIDS program clinic in the Southern United States.
Language	English
Publishing date	2020-09-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	2757767-3
ISSN	2328-8957
ISSN	2328-8957
DOI	10.1093/ofid/ofaa423
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Article ; Online: Knowledge of Hepatitis C Risk Factors is Lower in High Incidence Regions.

Knick, Terry / Sherbuk, Jacqueline E / Dillingham, Rebecca

Journal of community health

2019 Volume 44, Issue 1, Page(s) 12–15

Abstract: Despite ambitious goals to eliminate hepatitis C virus (HCV) in the United States by 2030, the majority of those infected are not aware of their diagnosis, and only a small minority have been cured. A lack of knowledge regarding risk factors and ... ...

Abstract	Despite ambitious goals to eliminate hepatitis C virus (HCV) in the United States by 2030, the majority of those infected are not aware of their diagnosis, and only a small minority have been cured. A lack of knowledge regarding risk factors and treatment may contribute to low cure rates. We aimed to evaluate HCV knowledge and the association of risk factor knowledge with HCV incidence. In fall 2017, a survey regarding HCV knowledge was disseminated through social media, web link, and in person throughout the state of Virginia. The survey was completed by 613 individuals. Residents of high-incidence counties identified fewer risk factors (5.6 vs 6.1 of 9, p = 0.04), a difference that remained significant when controlling for education and age (p = 0.03). Fewer participants in the high-incidence group recognized snorting drugs to be a risk factor (25% vs 36%, p = 0.01). Only 38% of all respondents correctly identified HCV to be curable. Knowledge of HCV risk factors is lower in high incidence regions. These results identify a critical knowledge gap in the general population at a time of ongoing HCV transmission. Public health interventions must target these gaps in high-incidence regions as part of comprehensive disease prevention programs.
MeSH term(s)	Health Knowledge, Attitudes, Practice ; Hepacivirus ; Hepatitis C/complications ; Hepatitis C/epidemiology ; Humans ; Incidence ; Risk Factors ; Substance-Related Disorders/complications ; Substance-Related Disorders/epidemiology ; Virginia/epidemiology
Language	English
Publishing date	2019-04-23
Publishing country	Netherlands
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	426631-6
ISSN	1573-3610 ; 0094-5145
ISSN (online)	1573-3610
ISSN	0094-5145
DOI	10.1007/s10900-018-0545-6
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Article ; Online: Improved mortality in Staphylococcus aureus bacteremia with the involvement of antimicrobial stewardship team and infectious disease consultation.

Sherbuk, Jacqueline E / McManus, Dayna / Topal, Jeffrey E / Malinis, Maricar

Infection control and hospital epidemiology

2019 Volume 40, Issue 8, Page(s) 932–935

Abstract: A retrospective study was conducted to evaluate the value of the antimicrobial stewardship team (AST) combined with infectious diseases consultation (IDC) on management and outcomes of Staphylococcus aureus bacteremia (SAB) in a tertiary-care academic ... ...

Abstract	A retrospective study was conducted to evaluate the value of the antimicrobial stewardship team (AST) combined with infectious diseases consultation (IDC) on management and outcomes of Staphylococcus aureus bacteremia (SAB) in a tertiary-care academic center. Involvement of AST or IDC was associated with reduced mortality of SAB.
MeSH term(s)	Aged ; Antimicrobial Stewardship ; Bacteremia/drug therapy ; Databases, Factual ; Female ; Humans ; Male ; Middle Aged ; Referral and Consultation ; Retrospective Studies ; Staphylococcal Infections/drug therapy ; Staphylococcus aureus/drug effects
Language	English
Publishing date	2019-06-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	639378-0
ISSN	1559-6834 ; 0195-9417 ; 0899-823X
ISSN (online)	1559-6834
ISSN	0195-9417 ; 0899-823X
DOI	10.1017/ice.2019.136
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Article: Financial, food, and housing insecurity due to COVID-19 among at risk people living with HIV in a non-urban Ryan White HIV/AIDS program clinic

Sherbuk, Jacqueline E. / Williams, Brooke / McManus, Kathleen A. / Dillingham, Rebecca

Open Forum Infectious Diseases

Abstract: COVID-19 negatively impacts social determinants of health that contribute to disparities for people living with HIV Insecurity of food, housing, and employment increased significantly in April 2020 among patients with lower incomes at a Ryan White HIV/ ... ...

Abstract	COVID-19 negatively impacts social determinants of health that contribute to disparities for people living with HIV Insecurity of food, housing, and employment increased significantly in April 2020 among patients with lower incomes at a Ryan White HIV/AIDS program clinic in the Southern United States
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #787253
Database	COVID19

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Article ; Online: Adapting an m-Health Intervention for Spanish-Speaking Latinx People Living with HIV in the Nonurban Southern United States.

Flickinger, Tabor E / Sherbuk, Jacqueline E / Petros de Guex, Kristen / Añazco Villarreal, Diego / Hilgart, Michelle / McManus, Kathleen A / Ingersoll, Karen / Dillingham, Rebecca

Telemedicine reports

2021 Volume 2, Issue 1, Page(s) 46–55

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2021-02-03
Document type	Journal Article
ISSN	2692-4366
ISSN (online)	2692-4366
DOI	10.1089/tmr.2020.0018
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Article: Disparities in Hepatitis C Linkage to Care in the Direct Acting Antiviral Era: Findings From a Referral Clinic With an Embedded Nurse Navigator Model.

Sherbuk, Jacqueline E / McManus, Kathleen A / Kemp Knick, Terry / Canan, Chelsea E / Flickinger, Tabor / Dillingham, Rebecca

Frontiers in public health

2019 Volume 7, Page(s) 362

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2019-11-27
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2711781-9
ISSN	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2019.00362
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Article ; Online: A qualitative study of perceived barriers to hepatitis C care among people who did not attend appointments in the non-urban US South.

Sherbuk, Jacqueline E / Tabackman, Alexa / McManus, Kathleen A / Kemp Knick, Terry / Schexnayder, Julie / Flickinger, Tabor E / Dillingham, Rebecca

Harm reduction journal

2020 Volume 17, Issue 1, Page(s) 64

Abstract: Background: Most people diagnosed with hepatitis C virus (HCV) have not linked to care, despite the availability of safe and effective treatment. We aimed to understand why people diagnosed with HCV have not pursued care in the non-urban Southern United ...

Abstract	Background: Most people diagnosed with hepatitis C virus (HCV) have not linked to care, despite the availability of safe and effective treatment. We aimed to understand why people diagnosed with HCV have not pursued care in the non-urban Southern United States. Methods: We conducted a survey and semi-structured interview with participants referred to an HCV clinic who did not attend an appointment between 2014 and 2018. Our clinic is located in a non-urban region of Virginia at a university hospital. Qualitative data collection was guided by the Health Belief Model (HBM). Data was analyzed using qualitative content analysis to identify key factors influencing patient perceptions regarding HCV and pursuit of care. Results: Over half of previously referred patients (N = 200) could not be reached by phone. Eleven participants enrolled, including 7 men and 4 women. Based on survey responses, unreliable transportation, unstable housing, substance use, and lack of insurance were common. Participants demonstrated good knowledge of HCV disease, complications, and treatment. On qualitative analysis of semi-structured interviews, final themes emerged from within and between HBM constructs. Emerging themes influencing patient perceptions included (1) structural barriers, (2) stigma, (3) prior experiences of HCV disease and treatment, (4) discordance between the recognized severity of HCV and expected impacts on one's own health, and (5) patient-provider relationship. Substance use was not identified to be a barrier to care. Conclusions: Participants perceived individual and structural barriers to linking to care. A strong HCV knowledge base was not sufficient to motivate pursuit of care. Efforts to improve linkage to care must address barriers at multiple levels, and system-level changes are needed. As the majority of previously referred patients could not be contacted by phone, current approaches to patient engagement are not effective for reaching these populations. Expansion of HCV care to primary care settings with an established patient-provider relationship or co-located treatment within substance use treatment programs may serve to increase access to HCV treatment.
MeSH term(s)	Aged ; Female ; Health Belief Model ; Health Knowledge, Attitudes, Practice ; Health Services Accessibility ; Hepacivirus ; Hepatitis C/psychology ; Hepatitis C/therapy ; Humans ; Interviews as Topic ; Male ; Medicare ; Patient Acceptance of Health Care ; Qualitative Research ; Referral and Consultation ; Social Stigma ; Suburban Population ; United States
Language	English
Publishing date	2020-09-18
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2146691-9
ISSN	1477-7517 ; 1477-7517
ISSN (online)	1477-7517
ISSN	1477-7517
DOI	10.1186/s12954-020-00409-9
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Article ; Online: Beyond Interpretation: The Unmet Need for Linguistically and Culturally Competent Care for Latinx People Living with HIV in a Southern Region with a Low Density of Spanish Speakers.

Sherbuk, Jacqueline E / Petros de Guex, Kristen / Anazco Villarreal, Diego / Knight, Sarah / McManus, Kathleen A / Flickinger, Tabor / Dillingham, Rebecca

AIDS research and human retroviruses

2020 Volume 36, Issue 11, Page(s) 933–941

Abstract: Latinx people living with HIV (PLWH) experience disparities in health outcomes and face unique barriers to care related to language, intersectional stigma, and immigration status. We aimed to explore the lived experience of Spanish-speaking Latinx PLWH ... ...

Abstract	Latinx people living with HIV (PLWH) experience disparities in health outcomes and face unique barriers to care related to language, intersectional stigma, and immigration status. We aimed to explore the lived experience of Spanish-speaking Latinx PLWH in the nonurban South to better understand how to improve care for this minority language population. We conducted semistructured interviews with 22 participants (10 men, 10 women, 2 transgender women) who were recruited from a Ryan White HIV/AIDS program (RWHAP) and a community-based organization. Almost all participants were foreign born. Emerging themes included language barriers, cultural differences, inadequate interpreter services, HIV-related and intersectional stigma, isolation, and relationships as a source of support. These barriers may contribute to disparities in outcomes for Latinx PLWH. New interventions are needed to overcome barriers, foster community, and ensure culturally tailored models of care. Potential clinic-level interventions include the development of specialized training for RWHAP interpreters and inclusion of interpreters in care teams.
MeSH term(s)	Culturally Competent Care ; Diagnostic Tests, Routine ; Female ; HIV Infections ; Humans ; Language ; Male ; Social Stigma
Language	English
Publishing date	2020-09-02
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	639130-8
ISSN	1931-8405 ; 0889-2229
ISSN (online)	1931-8405
ISSN	0889-2229
DOI	10.1089/AID.2020.0088
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