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  1. Article ; Online: Bleeding in COVID-19 severe pneumonia: The other side of abnormal coagulation pattern?

    Conti, Clara Benedetta / Henchi, Sonia / Coppeta, Giovanni Paolo / Testa, Sophie / Grassia, Roberto

    European journal of internal medicine

    2020  Volume 77, Page(s) 147–149

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; Prognosis ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-07
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2020.05.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Bleeding in COVID-19 severe pneumonia: The other side of abnormal coagulation pattern?

    Conti, Clara Benedetta / Henchi, Sonia / Coppeta, Giovanni Paolo / Testa, Sophie / Grassia, Roberto

    Eur J Intern Med

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #197714
    Database COVID19

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  3. Article ; Online: Bleeding in COVID-19 severe pneumonia

    Conti, Clara Benedetta / Henchi, Sonia / Coppeta, Giovanni Paolo / Testa, Sophie / Grassia, Roberto

    European Journal of Internal Medicine

    The other side of abnormal coagulation pattern?

    2020  Volume 77, Page(s) 147–149

    Keywords Internal Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 1038679-8
    ISSN 0953-6205
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2020.05.002
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Antibiotic therapy, supportive treatment and management of immunomodulation-inflammation response in community acquired pneumonia: review of recommendations.

    Mantero, Marco / Tarsia, Paolo / Gramegna, Andrea / Henchi, Sonia / Vanoni, Nicolò / Di Pasquale, Marta

    Multidisciplinary respiratory medicine

    2017  Volume 12, Page(s) 26

    Abstract: Community-acquired pneumonia is a common and serious disease, with high rates of morbidity and mortality. Management and treatment of community-acquired pneumonia are described in three main documents: the 2007 American Thoracic Society guidelines, the ... ...

    Abstract Community-acquired pneumonia is a common and serious disease, with high rates of morbidity and mortality. Management and treatment of community-acquired pneumonia are described in three main documents: the 2007 American Thoracic Society guidelines, the 2011 European Respiratory Society guidelines, and the 2009 British Thoracic Society guidelines, updated by the NICE in 2015. Despite the validity of current guidelines in improving prognosis and management of patients with community-acquired pneumonia, not all recommendations have high levels of evidence and there are still some controversial issues. In particular, there are some areas of low evidence such as the efficacy of an antibiotic molecule or scheme in patients with same risk factors; duration of antibiotic treatment, supportive therapy for acute respiratory failure and immunomodulation molecules. This review will summarize the main recommendations with high level of evidence and discuss the recommendations with lower evidence, analyzing the studies published after the guidelines' release.
    Language English
    Publishing date 2017-10-05
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 2677839-7
    ISSN 2049-6958 ; 1828-695X
    ISSN (online) 2049-6958
    ISSN 1828-695X
    DOI 10.1186/s40248-017-0106-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: First COVID-19 sub-intensive respiratory unit in Europe: the Italian experience.

    Henchi, Sonia / Conti, Clara Benedetta / Vanoni, Nicolò / Repossi, Alice Claudia / Cipolla, Giuseppe / Marra, Mirko / Esposti, Elena / Fiini, Michela / Raimondi Cominesi, Irene / Crepaldi, Monica / Scozzafava, Mariano

    Multidisciplinary respiratory medicine

    2020  Volume 15, Issue 1, Page(s) 682

    Abstract: European SARS-CoV-2 pandemic epicenter was detected in Northern Italy, in a little Italian town of Lodi province, the Lodi Hospital was therefore rapidly saturated, and in particularly the departments of respiratory diseases and Intensive Care Unit had ... ...

    Abstract European SARS-CoV-2 pandemic epicenter was detected in Northern Italy, in a little Italian town of Lodi province, the Lodi Hospital was therefore rapidly saturated, and in particularly the departments of respiratory diseases and Intensive Care Unit had been largely involved. In this paper, we describe how the first Sub-intensive Respiratory Unit in Europe completely dedicated to COVID-19 patients was organized and managed in our hospital. From February 25
    Keywords covid19
    Language English
    Publishing date 2020-06-23
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2677839-7
    ISSN 2049-6958 ; 1828-695X
    ISSN (online) 2049-6958
    ISSN 1828-695X
    DOI 10.4081/mrm.2020.682
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Utility and safety of bronchoscopy during the SARS-CoV-2 outbreak in Italy: a retrospective, multicentre study.

    Mondoni, Michele / Sferrazza Papa, Giuseppe Francesco / Rinaldo, Rocco / Faverio, Paola / Marruchella, Almerico / D'Arcangelo, Francesca / Pesci, Alberto / Pasini, Simone / Henchi, Sonia / Cipolla, Giuseppe / Tarantini, Francesco / Giuliani, Lisa / Di Marco, Fabiano / Saracino, Laura / Tomaselli, Stefano / Corsico, Angelo / Gasparini, Stefano / Bonifazi, Martina / Zuccatosta, Lina /
    Saderi, Laura / Pellegrino, Giulia / Davì, Matteo / Carlucci, Paolo / Centanni, Stefano / Sotgiu, Giovanni

    The European respiratory journal

    2020  Volume 56, Issue 4

    MeSH term(s) Betacoronavirus/isolation & purification ; Bronchoalveolar Lavage Fluid/virology ; Bronchoscopy/adverse effects ; Bronchoscopy/methods ; Bronchoscopy/statistics & numerical data ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques/methods ; Coinfection/diagnosis ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/physiopathology ; Coronavirus Infections/virology ; Disease Transmission, Infectious/prevention & control ; Early Diagnosis ; Female ; Humans ; Infection Control/methods ; Italy/epidemiology ; Male ; Middle Aged ; Outcome Assessment, Health Care ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/physiopathology ; Pneumonia, Viral/virology ; Procedures and Techniques Utilization ; SARS-CoV-2 ; Symptom Assessment/methods ; Symptom Assessment/statistics & numerical data
    Keywords covid19
    Language English
    Publishing date 2020-10-15
    Publishing country England
    Document type Letter ; Multicenter Study ; Observational Study
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.02767-2020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2322: Show issues Location:
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    Zs.MO 292: Show issues

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  7. Article ; Online: Assessment of acute bronchodilator effects from specific airway resistance changes in stable COPD patients.

    Santus, Pierachille / Radovanovic, Dejan / Henchi, Sonia / Di Marco, Fabiano / Centanni, Stefano / D'Angelo, Edgardo / Pecchiari, Matteo

    Respiratory physiology & neurobiology

    2014  Volume 197, Page(s) 36–45

    Abstract: Background: In COPD patients, reversibility is currently evaluated from the changes of forced expiratory volume at 1s (ΔFEV1) and forced vital capacity (ΔFVC). By lowering peripheral airway smooth muscle tone, bronchodilators should decrease dynamic ... ...

    Abstract Background: In COPD patients, reversibility is currently evaluated from the changes of forced expiratory volume at 1s (ΔFEV1) and forced vital capacity (ΔFVC). By lowering peripheral airway smooth muscle tone, bronchodilators should decrease dynamic hyperinflation, gas trapping, and possibly dyspnea at rest. Hence, we hypothesize that specific airway resistance changes (ΔsRAW) should better characterize the acute response to bronchodilators.
    Methods: On two days, 60 COPD patients underwent dyspnea evaluation (VAS score) and pulmonary function testing at baseline and one hour after placebo or 300μg indacaterol administration.
    Results: Spirographic and ΔsRAW-based criteria identified as responders 24 and 45 patients, respectively. ΔsRAW correlated with changes of intrathoracic gas volume (ΔITGV) (r=0.61; p<0.001), residual volume (ΔRV) (r=0.60; p<0.001), ΔFVC (r=0.44; p=0.001), and ΔVAS (r=0.73; p<0.001), while ΔFEV1 correlated only with ΔFVC (r=0.34; p=0.008). Significant differences in terms of ΔITGV (p=0.002), ΔRV (p=0.023), and ΔVAS (p<0.001) occurred only if patients were stratified according to ΔsRAW.
    Conclusions: In assessing the acute functional effect of bronchodilators, ΔsRAW-based criterion is preferable to FEV1-FVC-based criteria, being more closely related to bronchodilator-induced improvements of lung mechanics and dyspnea at rest.
    MeSH term(s) Adrenergic beta-Agonists/therapeutic use ; Aged ; Airway Resistance/drug effects ; Bronchodilator Agents/therapeutic use ; Cross-Over Studies ; Double-Blind Method ; Dyspnea/drug therapy ; Dyspnea/physiopathology ; Female ; Humans ; Indans/therapeutic use ; Lung Volume Measurements ; Male ; Plethysmography ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Pulmonary Disease, Chronic Obstructive/physiopathology ; Quinolones/therapeutic use ; Respiratory Function Tests ; Time Factors ; Treatment Outcome
    Chemical Substances Adrenergic beta-Agonists ; Bronchodilator Agents ; Indans ; Quinolones ; indacaterol (8OR09251MQ)
    Language English
    Publishing date 2014-06-15
    Publishing country Netherlands
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2077867-3
    ISSN 1878-1519 ; 1569-9048
    ISSN (online) 1878-1519
    ISSN 1569-9048
    DOI 10.1016/j.resp.2014.03.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 519: Show issues Location:
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  8. Article: Role of Bronchoscopy During SARS-CoV-2 Outbreak in Italy: A Retrospective, Multicenter Study

    Mondoni, Michele Sferrazza Papa Giuseppe Francesco Rinaldo Rocco Faverio Paola Marruchella Almerico Arcangelo Francesca Pesci Alberto Pasini Simone Henchi Sonia Cipolla Giuseppe Tarantini Francesco Giuliani Lisa Di Marco Fabiano Saracino Laura Tomaselli Stefano Corsico Angelo Gasparini Stefano Bonifazi Martina Zuccatosta Lina Saderi Laura Pellegrino Giulia Davà Matteo Carlucci Paolo Centanni Stefano Sotgiu Giovanni

    Abstract: Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been spreading throughout Italy since February 2020 Limited data are ... ...

    Abstract Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been spreading throughout Italy since February 2020 Limited data are ava
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #1672
    Database COVID19

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  9. Article: Utility and safety of bronchoscopy during the SARS-CoV-2 outbreak in Italy: a retrospective, multicentre study

    Mondoni, Michele / Sferrazza Papa, Giuseppe Francesco / Rinaldo, Rocco / Faverio, Paola / Marruchella, Almerico / D039, / Arcangelo, Francesca / Pesci, Alberto / Pasini, Simone / Henchi, Sonia / Cipolla, Giuseppe / Tarantini, Francesco / Giuliani, Lisa / Di Marco, Fabiano / Saracino, Laura / Tomaselli, Stefano / Corsico, Angelo / Gasparini, Stefano / Bonifazi, Martina /
    Zuccatosta, Lina / Saderi, Laura / Pellegrino, Giulia / Davì, Matteo / Carlucci, Paolo / Centanni, Stefano / Sotgiu, Giovanni

    Eur. respir. j

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #733053
    Database COVID19

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  10. Article ; Online: Role of Bronchoscopy During SARS-CoV-2 Outbreak in Italy

    Mondoni, Michele / Sferrazza Papa, Giuseppe Francesco / Rinaldo, Rocco / Faverio, Paola / Marruchella, Almerico / D’Arcangelo, Francesca / Pesci, Alberto / Pasini, Simone / Henchi, Sonia / Cipolla, Giuseppe / Tarantini, Francesco / Giuliani, Lisa / Di Marco, Fabiano / Saracino, Laura / Tomaselli, Stefano / Corsico, Angelo / Gasparini, Stefano / Bonifazi, Martina / Zuccatosta, Lina /
    Saderi, Laura / Pellegrino, Giulia / Davì, Matteo / Carlucci, Paolo / Centanni, Stefano / Sotgiu, Giovanni

    SSRN Electronic Journal ; ISSN 1556-5068

    A Retrospective, Multicenter Study

    2020  

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.2139/ssrn.3608140
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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