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  1. Article ; Online: Is a Potassium-Competitive Acid Blocker Truly Superior to Proton Pump Inhibitors in Terms of

    Sue, Soichiro / Maeda, Shin

    Gut and liver

    2021  Volume 15, Issue 6, Page(s) 799–810

    Abstract: Vonoprazan (VPZ), a new potassium-competitive acid blocker, has been approved and used ... ...

    Abstract Vonoprazan (VPZ), a new potassium-competitive acid blocker, has been approved and used for
    MeSH term(s) Amoxicillin/therapeutic use ; Anti-Bacterial Agents/therapeutic use ; Clarithromycin/therapeutic use ; Drug Therapy, Combination ; Helicobacter Infections/drug therapy ; Helicobacter pylori ; Humans ; Metronidazole/therapeutic use ; Potassium/therapeutic use ; Proton Pump Inhibitors/therapeutic use ; Treatment Outcome
    Chemical Substances Anti-Bacterial Agents ; Proton Pump Inhibitors ; Metronidazole (140QMO216E) ; Amoxicillin (804826J2HU) ; Clarithromycin (H1250JIK0A) ; Potassium (RWP5GA015D)
    Language English
    Publishing date 2021-04-13
    Publishing country Korea (South)
    Document type Journal Article ; Review
    ZDB-ID 2399010-7
    ISSN 2005-1212 ; 1976-2283
    ISSN (online) 2005-1212
    ISSN 1976-2283
    DOI 10.5009/gnl20242
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6610: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Prospective Study of Vonoprazan-Based First-Line Triple Therapy with Amoxicillin and Metronidazole for Clarithromycin-Resistant

    Sue, Soichiro / Suzuki, Yuichi / Sasaki, Tomohiko / Kaneko, Hiroaki / Irie, Kuniyasu / Komatsu, Kazuto / Maeda, Shin

    Journal of clinical medicine

    2023  Volume 12, Issue 17

    Abstract: Aim: This was a prospective, multicenter, single-arm intervention, against historical controls, study of the efficacy of a vonoprazan-based 7-day triple regimen with metronidazole (VPZ-AMPC-MNZ) as a first-line therapy for eradicating clarithromycin- ... ...

    Abstract Aim: This was a prospective, multicenter, single-arm intervention, against historical controls, study of the efficacy of a vonoprazan-based 7-day triple regimen with metronidazole (VPZ-AMPC-MNZ) as a first-line therapy for eradicating clarithromycin-resistant
    Methods: We enrolled 35 patients positive for clarithromycin-resistant
    Results: The intention-to-treat (ITT) and per-protocol (PP) eradication rates of VPZ-AMPC-MNZ were both 100% (95% confidence interval (95% CI) 90.0-100%,
    Conclusions: The findings suggest that 7-day VPZ-AMPC-MNZ was superior to 7-day VPZ-AMPC-CAM as a first-line regimen for eradicating clarithromycin-resistant
    Language English
    Publishing date 2023-08-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12175443
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The usefulness of texture and color enhancement imaging to identify the minor papilla orifice.

    Goda, Yoshihiro / Irie, Kuniyasu / Anan, Hideyuki / Suzuki, Yuichi / Ikeda, Aya / Ikeda, Ryosuke / Kaneko, Hiroaki / Sue, Soichiro / Miwa, Haruo / Maeda, Shin

    DEN open

    2024  Volume 4, Issue 1, Page(s) e358

    Abstract: In clinical cases of pancreas divisum, endoscopic retrograde cholangiopancreatography often necessitates cannulation of the pancreatic duct through the minor papilla. Nevertheless, this procedure can be challenging because of the small size of the minor ... ...

    Abstract In clinical cases of pancreas divisum, endoscopic retrograde cholangiopancreatography often necessitates cannulation of the pancreatic duct through the minor papilla. Nevertheless, this procedure can be challenging because of the small size of the minor papilla and the difficulty in visualizing the ductal orifice. A new image-enhanced endoscopy technique called texture and color enhancement imaging (TXI) has been developed, which enhances texture, brightness, and color compared with white-light imaging, resulting in subtle differences in the surface mucosa. Herein, we describe the case of a 73-year-old man with pancreas divisum in whom TXI was useful in identifying the orifice of the minor papilla. He was referred to our hospital with repetitive acute exacerbation of chronic pancreatitis. Since contrast-enhanced computed tomography revealed a pancreatic stone in the main pancreatic duct, endoscopic retrograde cholangoepancreatography was performed as a therapeutic intervention. Despite the initial difficulty in identifying the orifice of the minor papilla on white-light imaging, TXI enhanced its visibility successfully, enabling dorsal pancreatic duct cannulation via the minor papilla. Subsequently, endoscopic pancreatic sphincterotomy was performed and a 6Fr plastic stent was placed. Post-endoscopic therapy, the patient's abdominal pain was relieved. TXI was useful in identifying the minor papilla orifice and led to successful cannulation.
    Language English
    Publishing date 2024-04-04
    Publishing country Australia
    Document type Case Reports
    ISSN 2692-4609
    ISSN (online) 2692-4609
    DOI 10.1002/deo2.358
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Comparison of metronidazole

    Sue, Soichiro / Oka, Hiroyuki / Kunishi, Yosuke / Suzuki, Yuichi / Suzuki, Shingo / Kaneko, Takashi / Komatsu, Kazuo / Naito, Makoto / Kato, Yoshio / Sasaki, Tomohiko / Kaneko, Hiroaki / Irie, Kuniyasu / Kondo, Masaaki / Maeda, Shin

    JGH open : an open access journal of gastroenterology and hepatology

    2024  Volume 8, Issue 4, Page(s) e13069

    Abstract: Background and aim: To date, no randomized trials have compared the efficacy of 7-day vonoprazan, amoxicillin, and metronidazole triple therapy (VAM) : Methods: This prospective multicenter randomized trial was performed in Japan and involved 124 : ...

    Abstract Background and aim: To date, no randomized trials have compared the efficacy of 7-day vonoprazan, amoxicillin, and metronidazole triple therapy (VAM)
    Methods: This prospective multicenter randomized trial was performed in Japan and involved 124
    Results: The intention-to-treat and per-protocol eradication rates of VAM were 91.3% (95% confidence interval [CI], 82.0-96.7%) and 92.6% (95% CI, 83.7-97.6%), respectively, and those of VAC were 89.1% (95% CI, 77.8-95.9%) and 96.1% (95% CI, 86.5-99.5%), respectively. No significant difference was observed between VAM and VAC in either analysis (
    Conclusions: These findings suggest that VAM as a first-line treatment in Japan can be categorized as grade B (intention-to-treat cure rate of 90-95%) and have potential as a first-line national insurance -approved regimen.
    Language English
    Publishing date 2024-04-22
    Publishing country Australia
    Document type Journal Article
    ISSN 2397-9070
    ISSN (online) 2397-9070
    DOI 10.1002/jgh3.13069
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Risk assessment of metachronous gastric cancer after endoscopic submucosal dissection based on endoscopic intestinal metaplasia.

    Iizuka, Chino / Sue, Soichiro / Onodera, Sho / Ikeda, Aya / Ikeda, Ryosuke / Goda, Yoshihiro / Irie, Kuniyasu / Kaneko, Hiroaki / Maeda, Shin

    JGH open : an open access journal of gastroenterology and hepatology

    2023  Volume 7, Issue 11, Page(s) 783–789

    Abstract: Background and aim: The incidence of metachronous gastric cancer (MGC) after endoscopic treatment for early gastric cancer (EGC) is high, but a method of risk assessment for MGC based on endoscopic findings has not been established. In this study, we ... ...

    Abstract Background and aim: The incidence of metachronous gastric cancer (MGC) after endoscopic treatment for early gastric cancer (EGC) is high, but a method of risk assessment for MGC based on endoscopic findings has not been established. In this study, we focused on endoscopic intestinal metaplasia (IM) and investigated the risk for MGC after endoscopic submucosal dissection (ESD) for EGC.
    Methods: This retrospective observational study involved patients who underwent curative ESD for EGC from April 2015 to January 2021. We assessed endoscopic IM using the pretreatment endoscopic examination images. The severity of endoscopic IM was classified into four levels: 0 (none), 1 (mild), 2 (moderate), and 3 (severe). Four different gastric areas were evaluated. We divided the patients into a low-score group and a high-score group, and compared the cumulative incidence of MGC.
    Results: In total, 156 patients who met the inclusion criteria were followed up for at least 12 months after ESD, and MGC developed in 14 patients during a mean period oof 41.5 months. The endoscopic IM scores in the lesser curvature of the antrum, lesser curvature of the corpus, and greater curvature of the corpus were higher in patients with MGC than in those without MGC. In the corpus, the 5-year cumulative incidence of MGC was significantly higher in the high-score group than in the low-score group (29.8%
    Conclusion: The severity of endoscopic corpus IM was associated with MGC. Thus, patients with severe corpus IM at the time of ESD require careful examination and intensive follow-up.
    Language English
    Publishing date 2023-10-28
    Publishing country Australia
    Document type Journal Article
    ISSN 2397-9070
    ISSN (online) 2397-9070
    DOI 10.1002/jgh3.12989
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Helicobacter pylori

    Sue, Soichiro / Sasaki, Tomohiko / Kaneko, Hiroaki / Irie, Kuniyasu / Kondo, Masaaki / Maeda, Shin

    JGH open : an open access journal of gastroenterology and hepatology

    2021  Volume 5, Issue 2, Page(s) 307–311

    Abstract: Background and aim: To assess the efficacy and safety of 7-day : Methods: This was a registered prospective intervention study. Patients with penicillin allergy who were diagnosed with : Results: The eradication rate of 7-day VPZ-MNZ-SFTX therapy ... ...

    Abstract Background and aim: To assess the efficacy and safety of 7-day
    Methods: This was a registered prospective intervention study. Patients with penicillin allergy who were diagnosed with
    Results: The eradication rate of 7-day VPZ-MNZ-SFTX therapy was 88.2% (95% confidence interval: 63.6-98.5%;
    Conclusion: Rescue
    Language English
    Publishing date 2021-01-23
    Publishing country Australia
    Document type Journal Article
    ISSN 2397-9070
    ISSN (online) 2397-9070
    DOI 10.1002/jgh3.12492
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Vonoprazan and high-dose amoxicillin dual therapy for

    Sue, Soichiro / Kondo, Masaaki / Sato, Takeshi / Oka, Hiroyuki / Sanga, Katsuyuki / Ogashiwa, Tsuyoshi / Matsubayashi, Mao / Kaneko, Hiroaki / Irie, Kuniyasu / Maeda, Shin

    JGH open : an open access journal of gastroenterology and hepatology

    2022  Volume 7, Issue 1, Page(s) 55–60

    Abstract: Background: To date, no interventional trial has assessed the efficacy and safety of vonoprazan and high-dose (500 mg four times daily, 2000 mg/day) amoxicillin dual therapy in terms of : Methods: This prospective, dual-center, single-arm ... ...

    Abstract Background: To date, no interventional trial has assessed the efficacy and safety of vonoprazan and high-dose (500 mg four times daily, 2000 mg/day) amoxicillin dual therapy in terms of
    Methods: This prospective, dual-center, single-arm interventional study was performed in Japan. Twenty
    Results: The intention-to-treat and per-protocol eradication rates were 90% (95% confidence interval [CI] 68.3-98.8%,
    Conclusion: Vonoprazan/high-dose amoxicillin dual therapy can be a safe standard first-line therapy. We are now undergoing a randomized controlled trial comparing dual therapy and vonoprazan-based triple therapy.
    Language English
    Publishing date 2022-12-08
    Publishing country Australia
    Document type Journal Article
    ISSN 2397-9070
    ISSN (online) 2397-9070
    DOI 10.1002/jgh3.12852
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Response to: Comment on "First-Line

    Sue, Soichiro / Suzuki, Nobumi / Shibata, Wataru / Sasaki, Tomohiko / Yamada, Hiroaki / Kaneko, Hiroaki / Tamura, Toshihide / Ishii, Tomohiro / Kondo, Masaaki / Maeda, Shin

    Gastroenterology research and practice

    2018  Volume 2018, Page(s) 8046838

    Language English
    Publishing date 2018-03-22
    Publishing country Egypt
    Document type Journal Article ; Comment
    ZDB-ID 2435460-0
    ISSN 1687-630X ; 1687-6121
    ISSN (online) 1687-630X
    ISSN 1687-6121
    DOI 10.1155/2018/8046838
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Helicobacter pylori-Induced Signaling Pathways Contribute to Intestinal Metaplasia and Gastric Carcinogenesis

    Soichiro Sue / Wataru Shibata / Shin Maeda

    BioMed Research International, Vol

    2015  Volume 2015

    Abstract: Helicobacter pylori (H. pylori) induces chronic gastric inflammation, atrophic gastritis, intestinal metaplasia, and cancer. Although the risk of gastric cancer increases exponentially with the extent of atrophic gastritis, the precise mechanisms of ... ...

    Abstract Helicobacter pylori (H. pylori) induces chronic gastric inflammation, atrophic gastritis, intestinal metaplasia, and cancer. Although the risk of gastric cancer increases exponentially with the extent of atrophic gastritis, the precise mechanisms of gastric carcinogenesis have not been fully elucidated. H. pylori induces genetic and epigenetic changes in gastric epithelial cells through activating intracellular signaling pathways in a cagPAI-dependent manner. H. pylori eventually induces gastric cancer with chromosomal instability (CIN) or microsatellite instability (MSI), which are classified as two major subtypes of gastric cancer. Elucidation of the precise mechanisms of gastric carcinogenesis will also be important for cancer therapy.
    Keywords Medicine ; R
    Language English
    Publishing date 2015-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Helicobacter pylori-Induced Signaling Pathways Contribute to Intestinal Metaplasia and Gastric Carcinogenesis.

    Sue, Soichiro / Shibata, Wataru / Maeda, Shin

    BioMed research international

    2015  Volume 2015, Page(s) 737621

    Abstract: Helicobacter pylori (H. pylori) induces chronic gastric inflammation, atrophic gastritis, intestinal metaplasia, and cancer. Although the risk of gastric cancer increases exponentially with the extent of atrophic gastritis, the precise mechanisms of ... ...

    Abstract Helicobacter pylori (H. pylori) induces chronic gastric inflammation, atrophic gastritis, intestinal metaplasia, and cancer. Although the risk of gastric cancer increases exponentially with the extent of atrophic gastritis, the precise mechanisms of gastric carcinogenesis have not been fully elucidated. H. pylori induces genetic and epigenetic changes in gastric epithelial cells through activating intracellular signaling pathways in a cagPAI-dependent manner. H. pylori eventually induces gastric cancer with chromosomal instability (CIN) or microsatellite instability (MSI), which are classified as two major subtypes of gastric cancer. Elucidation of the precise mechanisms of gastric carcinogenesis will also be important for cancer therapy.
    MeSH term(s) Carcinogenesis/genetics ; Epithelial Cells/microbiology ; Epithelial Cells/pathology ; Helicobacter pylori/pathogenicity ; Humans ; Intestines/microbiology ; Intestines/pathology ; Metaplasia/genetics ; Metaplasia/microbiology ; Metaplasia/pathology ; Microsatellite Instability ; Signal Transduction ; Stomach Neoplasms/genetics ; Stomach Neoplasms/microbiology ; Stomach Neoplasms/pathology
    Language English
    Publishing date 2015
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2698540-8
    ISSN 2314-6141 ; 2314-6133
    ISSN (online) 2314-6141
    ISSN 2314-6133
    DOI 10.1155/2015/737621
    Database MEDical Literature Analysis and Retrieval System OnLINE

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