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  1. Article ; Online: Opinion "POLE": Considering All Factors in Early-Stage Endometrial Cancer.

    Han, Kathy / Leung, Eric

    International journal of radiation oncology, biology, physics

    2023  Volume 117, Issue 2, Page(s) 299–300

    MeSH term(s) Humans ; Female ; Endometrial Neoplasms/radiotherapy
    Language English
    Publishing date 2023-08-31
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 197614-x
    ISSN 1879-355X ; 0360-3016
    ISSN (online) 1879-355X
    ISSN 0360-3016
    DOI 10.1016/j.ijrobp.2023.07.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Controlling avian influenza.

    Leung, Kathy / Lam, Tommy T Y / Wu, Joseph T

    BMJ (Clinical research ed.)

    2023  Volume 380, Page(s) 560

    MeSH term(s) Animals ; Humans ; Influenza in Birds/epidemiology ; Influenza in Birds/prevention & control ; Influenza, Human/epidemiology ; Influenza, Human/prevention & control ; Disease Outbreaks
    Language English
    Publishing date 2023-03-14
    Publishing country England
    Document type Editorial
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.p560
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Quantifying the uncertainty of CovidSim.

    Leung, Kathy / Wu, Joseph T

    Nature computational science

    2021  Volume 1, Issue 2, Page(s) 98–99

    Language English
    Publishing date 2021-02-22
    Publishing country United States
    Document type Journal Article
    ISSN 2662-8457
    ISSN (online) 2662-8457
    DOI 10.1038/s43588-021-00031-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Crowdsourcing data to mitigate epidemics.

    Leung, Gabriel M / Leung, Kathy

    The Lancet. Digital health

    2020  Volume 2, Issue 4, Page(s) e156–e157

    MeSH term(s) COVID-19 ; Crowdsourcing ; Disease Outbreaks/prevention & control ; Humans ; Pandemics ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-02-20
    Publishing country England
    Document type Journal Article ; Comment
    ISSN 2589-7500
    ISSN (online) 2589-7500
    DOI 10.1016/S2589-7500(20)30055-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Estimating the Epidemic Size of Superspreading Coronavirus Outbreaks in Real Time: Quantitative Study.

    Lau, Kitty Y / Kang, Jian / Park, Minah / Leung, Gabriel / Wu, Joseph T / Leung, Kathy

    JMIR public health and surveillance

    2024  Volume 10, Page(s) e46687

    Abstract: Background: Novel coronaviruses have emerged and caused major epidemics and pandemics in the past 2 decades, including SARS-CoV-1, MERS-CoV, and SARS-CoV-2, which led to the current COVID-19 pandemic. These coronaviruses are marked by their potential to ...

    Abstract Background: Novel coronaviruses have emerged and caused major epidemics and pandemics in the past 2 decades, including SARS-CoV-1, MERS-CoV, and SARS-CoV-2, which led to the current COVID-19 pandemic. These coronaviruses are marked by their potential to produce disproportionally large transmission clusters from superspreading events (SSEs). As prompt action is crucial to contain and mitigate SSEs, real-time epidemic size estimation could characterize the transmission heterogeneity and inform timely implementation of control measures.
    Objective: This study aimed to estimate the epidemic size of SSEs to inform effective surveillance and rapid mitigation responses.
    Methods: We developed a statistical framework based on back-calculation to estimate the epidemic size of ongoing coronavirus SSEs. We first validated the framework in simulated scenarios with the epidemiological characteristics of SARS, MERS, and COVID-19 SSEs. As case studies, we retrospectively applied the framework to the Amoy Gardens SARS outbreak in Hong Kong in 2003, a series of nosocomial MERS outbreaks in South Korea in 2015, and 2 COVID-19 outbreaks originating from restaurants in Hong Kong in 2020.
    Results: The accuracy and precision of the estimation of epidemic size of SSEs improved with longer observation time; larger SSE size; and more accurate prior information about the epidemiological characteristics, such as the distribution of the incubation period and the distribution of the onset-to-confirmation delay. By retrospectively applying the framework, we found that the 95% credible interval of the estimates contained the true epidemic size after 37% of cases were reported in the Amoy Garden SARS SSE in Hong Kong, 41% to 62% of cases were observed in the 3 nosocomial MERS SSEs in South Korea, and 76% to 86% of cases were confirmed in the 2 COVID-19 SSEs in Hong Kong.
    Conclusions: Our framework can be readily integrated into coronavirus surveillance systems to enhance situation awareness of ongoing SSEs.
    MeSH term(s) Humans ; Pandemics ; Retrospective Studies ; COVID-19/epidemiology ; SARS-CoV-2 ; Disease Outbreaks/prevention & control ; Cross Infection
    Language English
    Publishing date 2024-02-12
    Publishing country Canada
    Document type Journal Article
    ISSN 2369-2960
    ISSN (online) 2369-2960
    DOI 10.2196/46687
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Managing waning vaccine protection against SARS-CoV-2 variants.

    Leung, Kathy / Wu, Joseph T

    Lancet (London, England)

    2021  Volume 399, Issue 10319, Page(s) 2–3

    MeSH term(s) Antibodies, Neutralizing ; COVID-19 ; Humans ; SARS-CoV-2 ; Vaccines
    Chemical Substances Antibodies, Neutralizing ; Vaccines
    Language English
    Publishing date 2021-12-20
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(21)02841-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Mixing patterns and the spread of pandemics.

    Leung, Kathy / Jia, Jayson S / Wu, Joseph T

    Nature computational science

    2022  Volume 2, Issue 9, Page(s) 561–562

    MeSH term(s) Humans ; Pandemics ; Models, Statistical ; Influenza, Human/epidemiology
    Language English
    Publishing date 2022-09-15
    Publishing country United States
    Document type Journal Article
    ISSN 2662-8457
    ISSN (online) 2662-8457
    DOI 10.1038/s43588-022-00312-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Cervical screening among Chinese females in the era of HPV vaccination: a population-based survey on screening uptake and regular screening following an 18-year organized screening program.

    Choi, Horace Cw / Leung, Kathy / Wu, Joseph T

    Journal of gynecologic oncology

    2023  Volume 35, Issue 2, Page(s) e20

    Abstract: Objective: China has a substantial disease burden of cervical cancer. To further understand preventive measures for reducing cervical cancer in China, this study aimed to correlate screening attendance and regular screening with human papillomavirus ( ... ...

    Abstract Objective: China has a substantial disease burden of cervical cancer. To further understand preventive measures for reducing cervical cancer in China, this study aimed to correlate screening attendance and regular screening with human papillomavirus (HPV) vaccination among Chinese females.
    Methods: This prospective questionnaire-based survey recruited Chinese females aged 25 or above in Hong Kong by random digit dialing telephone interviews in 2022. The survey studied women's practice of cervical screening and adherence to regular screening. Variables including HPV vaccination status and attendance of physical check-ups were involved in the questionnaire. Screening uptake and screening adherence were the main outcomes, which were measured as the proportion of women who reported having attended a cervical screening and screened regularly, respectively.
    Results: Out of 906 valid respondents, the reported cervical screening uptake was over 70% among females aged 30 or above and particularly over 80% among women aged 35-59; however, the uptake was only 46% among those aged 25-29. Adherence to regular screening was 50%-60% across ages 25-59 years and dropped to approximately 40% for women older than 60 years. Both screening uptake and adherence were associated with HPV vaccination, with adjusted odds ratios of 2.37 and 2.23, respectively. A large proportion of regularly screened women may be overscreened for screening more frequently than recommended.
    Conclusion: Responded Chinese females showed good cervical screening uptake but were moderately adherent to regular screening. Policymakers should emphasize the importance of regular screening and the recommended screening frequency by HPV vaccination status for better healthcare resource use.
    MeSH term(s) Female ; Humans ; Uterine Cervical Neoplasms/diagnosis ; Uterine Cervical Neoplasms/prevention & control ; Papillomavirus Infections/diagnosis ; Papillomavirus Infections/prevention & control ; Early Detection of Cancer ; Prospective Studies ; China/epidemiology ; Vaccination ; Papillomavirus Vaccines
    Chemical Substances Papillomavirus Vaccines
    Language English
    Publishing date 2023-10-18
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2478405-9
    ISSN 2005-0399 ; 2005-0380
    ISSN (online) 2005-0399
    ISSN 2005-0380
    DOI 10.3802/jgo.2024.35.e20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Estimating the transmission dynamics of SARS-CoV-2 Omicron BF.7 in Beijing after adjustment of the zero-COVID policy in November-December 2022.

    Leung, Kathy / Lau, Eric H Y / Wong, Carlos K H / Leung, Gabriel M / Wu, Joseph T

    Nature medicine

    2023  Volume 29, Issue 3, Page(s) 579–582

    Abstract: We tracked the effective reproduction number ( ... ...

    Abstract We tracked the effective reproduction number (R
    MeSH term(s) Humans ; Beijing/epidemiology ; SARS-CoV-2 ; COVID-19/epidemiology ; China/epidemiology ; Policy
    Language English
    Publishing date 2023-01-13
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1220066-9
    ISSN 1546-170X ; 1078-8956
    ISSN (online) 1546-170X
    ISSN 1078-8956
    DOI 10.1038/s41591-023-02212-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The gradual release exit strategy after lockdown against COVID-19.

    Leung, Kathy / Wu, Joseph T

    The Lancet regional health. Western Pacific

    2020  Volume 1, Page(s) 100008

    Language English
    Publishing date 2020-08-06
    Document type Journal Article
    ISSN 2666-6065
    ISSN (online) 2666-6065
    DOI 10.1016/j.lanwpc.2020.100008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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