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Article ; Online: Canadian medical student knowledge and attitudes toward female genital mutilation.

Market, Marisa / Grondin, Melanie / Boucher, Dominique M / Malic, Claudia

Education for health (Abingdon, England)

2023 Volume 36, Issue 1, Page(s) 38–46

Abstract: Background: Despite female genital mutilation/cutting (FGM/C) practices being an illegal form of gender-based violence in Canada, this practice impacts many Canadians. Lack of education and training among Canadian health-care providers has resulted in ... ...

Abstract	Background: Despite female genital mutilation/cutting (FGM/C) practices being an illegal form of gender-based violence in Canada, this practice impacts many Canadians. Lack of education and training among Canadian health-care providers has resulted in systematic barriers to care. Awareness and FGM/C-related education among Canadian health-care providers must be urgently assessed. Methods: Canadian medical students were recruited to complete an anonymous survey via E-mails distributed through their schools' student organization between January and March 2021. We evaluated student understanding of FGM/C, attitudes toward medicalization and legislation, and prior clinical experience using multiple choice, Likert scale, and open-response questions. Results: Respondents (n = 135) performed poorly on knowledge assessment questions (mean percent correct <50%). Only 10.4% of respondents indicated knowing how to involve appropriate authorities when necessary, and most never evaluate FGM/C in patient history (86.7%) or clinical examination (57.1%). Subgroup analysis revealed that prior education significantly improved knowledge scores and influenced students' behaviors and attitudes. About 92.2% of respondents supported the integration of FGM/C curricula in undergraduate medical education. Discussion: This study reveals that Canadian medical students have a poor understanding of FGM/C and are not prepared to identify affected patients or intervene when necessary. These results provide rationale for the implementation of FGM/C-learning modules in undergraduate medicine.
MeSH term(s)	Humans ; Female ; Circumcision, Female/methods ; Students, Medical ; Health Knowledge, Attitudes, Practice ; Canada ; Learning
Language	English
Publishing date	2023-12-04
Publishing country	India
Document type	Journal Article
ZDB-ID	1318454-4
ISSN	1469-5804 ; 1357-6283
ISSN (online)	1469-5804
ISSN	1357-6283
DOI	10.4103/efh.efh_18_22
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Article ; Online: Assessing the quality of reporting on quality improvement initiatives in plastic surgery: A systematic review.

Daniel Pereira, D / Market, Marisa R / Bell, Stephanie A / Malic, Claudia C

Journal of plastic, reconstructive & aesthetic surgery : JPRAS

2023 Volume 79, Page(s) 101–110

Abstract: Background: There has been a recent increase in the number and complexity of quality improvement studies in plastic surgery. To assist with the development of thorough quality improvement reporting practices, with the goal of improving the ... ...

Abstract	Background: There has been a recent increase in the number and complexity of quality improvement studies in plastic surgery. To assist with the development of thorough quality improvement reporting practices, with the goal of improving the transferability of these initiatives, we conducted a systematic review of studies describing the implementation of quality improvement initiatives in plastic surgery. We used the SQUIRE 2.0 (Standards for Quality Improvement Reporting Excellence) guideline to appraise the quality of reporting of these initiatives. Methods: English-language articles published in Embase, MEDLINE, CINAHL, and the Cochrane databases were searched. Quantitative studies evaluating the implementation of quality improvement initiatives in plastic surgery were included. The primary endpoint of interest in this review was the distribution of studies per SQUIRE 2.0 criteria scores in proportions. Abstract screening, full-text screening, and data extraction were completed independently and in duplicate by the review team. Results: We screened 7046 studies, of which 103 full texts were assessed, and 50 met inclusion criteria. In our assessment, only 7 studies (14%) met all 18 SQUIRE 2.0 criteria. SQUIRE 2.0 criteria that were met most frequently were abstract, problem description, rationale, and specific aims. The lowest SQUIRE 2.0 scores appeared in funding, conclusion, and interpretation criteria. Conclusions: Improvements in QI reporting in plastic surgery, especially in the realm of funding, costs, strategic trade-offs, project sustainability, and potential for spread to other contexts, will further advance the transferability of QI initiatives, which could lead to significant strides in improving patient care.
MeSH term(s)	Humans ; Quality Improvement ; Surgery, Plastic ; Plastic Surgery Procedures
Language	English
Publishing date	2023-02-08
Publishing country	Netherlands
Document type	Systematic Review ; Journal Article ; Review
ZDB-ID	2217750-4
ISSN	1878-0539 ; 1748-6815 ; 0007-1226
ISSN (online)	1878-0539
ISSN	1748-6815 ; 0007-1226
DOI	10.1016/j.bjps.2023.01.036
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Article ; Online: Postoperative Natural Killer Cell Dysfunction: The Prime Suspect in the Case of Metastasis Following Curative Cancer Surgery.

Market, Marisa / Tennakoon, Gayashan / Auer, Rebecca C

International journal of molecular sciences

2021 Volume 22, Issue 21

Abstract: Surgical resection is the foundation for the curative treatment of solid tumors. However, metastatic recurrence due to the difficulty in eradicating micrometastases remain a feared outcome. Paradoxically, despite the beneficial effects of surgical ... ...

Abstract	Surgical resection is the foundation for the curative treatment of solid tumors. However, metastatic recurrence due to the difficulty in eradicating micrometastases remain a feared outcome. Paradoxically, despite the beneficial effects of surgical removal of the primary tumor, the physiological stress resulting from surgical trauma serves to promote cancer recurrence and metastasis. The postoperative environment suppresses critical anti-tumor immune effector cells, including Natural Killer (NK) cells. The literature suggests that NK cells are critical mediators in the formation of metastases immediately following surgery. The following review will highlight the mechanisms that promote the formation of micrometastases by directly or indirectly inducing NK cell suppression following surgery. These include tissue hypoxia, neuroendocrine activation, hypercoagulation, the pro-inflammatory phase, and the anti-inflammatory phase. Perioperative therapeutic strategies designed to prevent or reverse NK cell dysfunction will also be examined for their potential to improve cancer outcomes by preventing surgery-induced metastases.
MeSH term(s)	Animals ; Humans ; Hypoxia ; Inflammation ; Killer Cells, Natural/pathology ; Neoplasms/physiopathology ; Neoplasms/surgery ; Postoperative Period
Language	English
Publishing date	2021-10-21
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms222111378
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Article ; Online: Multifaceted quality improvement initiatives improve rate of pediatric hand injury reduction.

Market, Marisa / Zhu-Pawlowsky, Julia / Bhatt, Maala / Cheung, Kevin

CJEM

2022 Volume 24, Issue 4, Page(s) 426–433

Abstract: Background: Hand fractures account for a significant proportion of all fractures seen in pediatric emergency departments (ED). It is essential for initial interventions to be successful to avoid unnecessary repeat interventions/complications. We sought ... ...

Abstract	Background: Hand fractures account for a significant proportion of all fractures seen in pediatric emergency departments (ED). It is essential for initial interventions to be successful to avoid unnecessary repeat interventions/complications. We sought to assess whether quality improvement interventions could decrease the rate of repeat reductions by plastic surgeons in our tertiary centre. Methods: We included patients ≤ 18 years of age who presented to ED with a hand injury from January 2014 to May 2019. Data were collected and presented over two plan-do-study-act cycles. The interventions comprised the dissemination of previous research identifying hand injuries requiring repeat reduction at our centre and commencement of a quality improvement initiative that coincided with hiring of a fellowship-trained pediatric hand surgeon and the implementation of an electronic medical record. In the second plan-do-study-act cycle, we implemented formal educational workshops for ED physicians and a standardized flowsheet in our electronic medical record to track patients with hand injuries. Results: We identified 272 hand injuries (136 in cycle 1, 136 in cycle 2) from January 2014 to May 2019. As a result of the implemented quality improvement initiatives, the proportion of hand injuries requiring repeat reduction decreased from 8.7% (n = 8) to 3.0% (n = 2) during cycle 1. This improvement was sustained during the 17-month-long (November 2017-May 2019) second cycle (3.0%, n = 6). Conclusion: This study highlights the importance of multifaceted interventions to achieve improved patient care, specifically the potential impact of specialized physicians, informal feedback and education, formal teaching workshops, and electronic medical records.
MeSH term(s)	Child ; Emergency Service, Hospital ; Fractures, Bone/epidemiology ; Fractures, Bone/therapy ; Hand Injuries/epidemiology ; Humans ; Quality Improvement
Language	English
Publishing date	2022-03-29
Publishing country	England
Document type	Journal Article
ISSN	1481-8043
ISSN (online)	1481-8043
DOI	10.1007/s43678-022-00279-z
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Article ; Online: Postoperative Natural Killer Cell Dysfunction

Marisa Market / Gayashan Tennakoon / Rebecca C. Auer

International Journal of Molecular Sciences, Vol 22, Iss 11378, p

The Prime Suspect in the Case of Metastasis Following Curative Cancer Surgery

2021 Volume 11378

Abstract	Surgical resection is the foundation for the curative treatment of solid tumors. However, metastatic recurrence due to the difficulty in eradicating micrometastases remain a feared outcome. Paradoxically, despite the beneficial effects of surgical removal of the primary tumor, the physiological stress resulting from surgical trauma serves to promote cancer recurrence and metastasis. The postoperative environment suppresses critical anti-tumor immune effector cells, including Natural Killer (NK) cells. The literature suggests that NK cells are critical mediators in the formation of metastases immediately following surgery. The following review will highlight the mechanisms that promote the formation of micrometastases by directly or indirectly inducing NK cell suppression following surgery. These include tissue hypoxia, neuroendocrine activation, hypercoagulation, the pro-inflammatory phase, and the anti-inflammatory phase. Perioperative therapeutic strategies designed to prevent or reverse NK cell dysfunction will also be examined for their potential to improve cancer outcomes by preventing surgery-induced metastases.
Keywords	surgery ; natural killer cells ; immune suppression ; cellular immunity ; cancer ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
Subject code	610 ; 616
Language	English
Publishing date	2021-10-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Hands-On Workshops Improve Emergency Department Physicians' Self-Reported Understanding of Pediatric Hand Injuries.

Market, Marisa / Zhu-Pawlowsky, Julia / Bhatt, Maala / Cheung, Kevin

Pediatric emergency care

2021 Volume 38, Issue 2, Page(s) e493–e496

Abstract: Objectives: The aims of this study were to assess emergency department (ED) physician perception of hand injuries and improve their understanding and confidence in treating these injuries.: Methods: Combined didactic and hands-on workshops for ED ... ...

Abstract	Objectives: The aims of this study were to assess emergency department (ED) physician perception of hand injuries and improve their understanding and confidence in treating these injuries. Methods: Combined didactic and hands-on workshops for ED physicians were developed and run by a team of medical students, plastic surgeons, and ED physicians. The workshops consisted of a short review by a hand surgeon followed by hands-on sessions involving radiograph assessment, administration of local anesthetic, closed reduction, and splinting. Two sessions, 6 months apart, were provided. The workshops were evaluated using preworkshop and postworkshop questionnaires to assess the following domains: confidence and competence in treating hand injuries, knowledge of basic hand injury care, and feedback on the intervention itself. Results: Fifty physicians participated in the workshops. After the workshops, physician recognition of hand fracture reduction as a critical skill increased. Self-efficacy ratings of fracture assessment, administration of local anesthetic, performing a reduction, and applying postreduction immobilization increased. Median scores on knowledge-testing questions also increased postintervention from 73.3% (95% confidence interval, 70.2-78.5) to 86.7% (95% confidence interval, 79.3-86.2) (P < 0.05). Finally, physicians reported that they found the intervention educational, useful, and important, and approximately 90% of participants indicated they intended to change their practice based on this intervention. Conclusions: Knowledge sharing between specialists and generalists through combined didactic and hands-on workshops is an effective and well-received method of refining physician knowledge and increasing confidence in treating subspecialty-specific clinical presentations.
MeSH term(s)	Child ; Emergency Service, Hospital ; Hand Injuries/therapy ; Humans ; Knowledge ; Physicians ; Self Report
Language	English
Publishing date	2021-06-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	632588-9
ISSN	1535-1815 ; 0749-5161
ISSN (online)	1535-1815
ISSN	0749-5161
DOI	10.1097/PEC.0000000000002459
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Article ; Online: Pediatric Hand Injuries Requiring Closed Reduction at a Tertiary Pediatric Care Center.

Market, Marisa / Bhatt, Maala / Agarwal, Amisha / Cheung, Kevin

Hand (New York, N.Y.)

2019 Volume 16, Issue 2, Page(s) 235–240

Abstract: Background: ...

Abstract	Background:
MeSH term(s)	Child ; Fractures, Bone/surgery ; Hand Injuries/surgery ; Humans ; Joint Dislocations ; Metacarpal Bones ; Retrospective Studies
Language	English
Publishing date	2019-06-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	2277325-3
ISSN	1558-9455 ; 1558-9447
ISSN (online)	1558-9455
ISSN	1558-9447
DOI	10.1177/1558944719850635
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Article ; Online: Assessing the Quality of Reporting on Quality Improvement Initiatives in Breast Reconstruction: A Systematic Review.

Daniel Pereira, Diego / Cormier, Nicholas S / Market, Marisa R / Frank, Simon G

Plastic and reconstructive surgery

2022 Volume 151, Issue 4, Page(s) 552e–562e

Abstract: Background: There has been a recent increase in the number and complexity of quality improvement (QI) studies in breast reconstruction. To assist with the development of thorough QI reporting practices, with the goal of improving the transferability of ... ...

Abstract	Background: There has been a recent increase in the number and complexity of quality improvement (QI) studies in breast reconstruction. To assist with the development of thorough QI reporting practices, with the goal of improving the transferability of these initiatives, the authors conducted a systematic review of studies describing the implementation of QI initiatives in breast reconstruction. The authors used the Standards for Quality Improvement Reporting Excellence (SQUIRE) 2.0 guideline to appraise the quality of reporting of these initiatives. Methods: English language articles published in Embase, MEDLINE, CINAHL, and the Cochrane databases were searched. Quantitative studies evaluating the implementation of QI initiatives in breast reconstruction were included. The primary endpoint of interest in this review was the distribution of studies according to SQUIRE 2.0 criteria scores in proportions. Abstracts and full-text screening, and data extraction were completed independently and in duplicate by the review team. Results: The authors screened 1107 studies, of which 53 full texts were assessed and 35 met inclusion criteria. In our assessment, only three studies (9%) met all 18 SQUIRE 2.0 criteria. SQUIRE 2.0 criteria that were met most frequently were abstract, problem description, rationale, and analysis. The lowest SQUIRE 2.0 scores appeared in the interpretation criteria. Conclusions: Significant opportunity exists to improve QI reporting in breast reconstruction, especially in the realm of costs, strategic tradeoffs, ethical considerations, project sustainability, and potential for spread to other contexts. Improvements in these areas will help to further advance the transferability of QI initiatives in breast reconstruction.
MeSH term(s)	Humans ; Quality Improvement ; Mammaplasty/standards
Language	English
Publishing date	2022-12-05
Publishing country	United States
Document type	Systematic Review ; Journal Article
ZDB-ID	208012-6
ISSN	1529-4242 ; 0032-1052 ; 0096-8501
ISSN (online)	1529-4242
ISSN	0032-1052 ; 0096-8501
DOI	10.1097/PRS.0000000000009983
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Article ; Online: Is innate immunity our best weapon for flattening the curve?

Angka, Leonard / Market, Marisa / Ardolino, Michele / Auer, Rebecca C

The Journal of clinical investigation

2020 Volume 130, Issue 8, Page(s) 3954–3956

MeSH term(s)	Animals ; Betacoronavirus/immunology ; Coronavirus Infections/epidemiology ; Coronavirus Infections/immunology ; Coronavirus Infections/prevention & control ; Humans ; Immunity, Innate ; Viral Zoonoses/epidemiology ; Viral Zoonoses/immunology ; Viral Zoonoses/prevention & control
Keywords	covid19
Language	English
Publishing date	2020-04-28
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	3067-3
ISSN	1558-8238 ; 0021-9738
ISSN (online)	1558-8238
ISSN	0021-9738
DOI	10.1172/JCI140530
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Article: Is innate immunity our best weapon for flattening the curve?

Angka, Leonard / Market, Marisa / Ardolino, Michele / Auer, Rebecca C

J Clin Invest

Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #574933
Database	COVID19

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