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  1. Article: Recommandations du Comité de transplantation et d’insuffisance rénale chronique (CTAFU) : revue narrative ou revue systématique ? Éditorial.

    Timsit, M O

    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie

    2021  Volume 31, Issue 1, Page(s) 1–3

    Title translation Editorial: The French Guidelines from CTAFU, narrative or systematic review?
    MeSH term(s) France ; Humans ; Kidney Failure, Chronic ; Kidney Transplantation ; Practice Guidelines as Topic ; Professional Staff Committees ; Systematic Reviews as Topic
    Language French
    Publishing date 2021-01-09
    Publishing country France
    Document type Comparative Study ; Editorial
    ZDB-ID 1186190-3
    ISSN 1166-7087
    ISSN 1166-7087
    DOI 10.1016/j.purol.2020.03.016
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  2. Article: Commentaire à la néphrectomie laparoscopique pour rein polykystique est faisable et reproductible.

    Timsit, M-O

    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie

    2013  Volume 23, Issue 6, Page(s) 425–426

    Title translation Comment to the laparoscopic nephrectomy for polycystic kidney is feasible and reproducible.
    MeSH term(s) Humans ; Laparoscopy ; Nephrectomy/methods ; Polycystic Kidney, Autosomal Dominant/surgery
    Language French
    Publishing date 2013-05
    Publishing country France
    Document type Journal Article
    ZDB-ID 1186190-3
    ISSN 1166-7087
    ISSN 1166-7087
    DOI 10.1016/j.purol.2012.10.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: End-to-side versus end-to-end uretero-ureteral anastomosis in preemptive kidney transplantation from living donors: A monocentric experience.

    Thillou, D / Timsit, M-O / Panthier, F / Hurel, S / Amrouche, L / Anglicheau, D / Méjean, A / Audenet, F

    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie

    2023  Volume 33, Issue 3, Page(s) 118–124

    Abstract: Purpose: End-to-end (ETE) pyeloureterostomy is an alternative to ureteroneocystostomy for urinary anastomosis during kidney transplantation (KT). In preemptive KT from living donors (PKT-LD), end-to-side (ETS) uretero-ureteral anastomosis could have the ...

    Abstract Purpose: End-to-end (ETE) pyeloureterostomy is an alternative to ureteroneocystostomy for urinary anastomosis during kidney transplantation (KT). In preemptive KT from living donors (PKT-LD), end-to-side (ETS) uretero-ureteral anastomosis could have the benefits of pyeloureterostomy without ligation of the native kidney ureter. This study aimed to compare ETS to ETE uretero-ureteral anastomosis in PKT-LD.
    Methods: A monocentric retrospective 8-year study included all consecutive cases of PKT-LD, excluding ureteroneocystomy anastomosis and homolateral nephrectomy. Two groups were compared: ETS and ETE. Perioperative data on graft function and urological complications were collected.
    Results: One hundred and six patients were included: 48 patients in the ETS group and 58 patients in the ETE group. Median follow-up was 37.5 months [17.3; 57.5]. The estimated glomerular filtration rate at postoperative day ten and 3 months was similar in both groups. The overall complication rate was 16%, with no significant difference between the 2 groups. There was one ureteral stenosis in each group. None of the patients in the ETS group presented urinary fistula, whereas it occurred in one (1.7%) in the ETE group. Back pain due to native kidney obstruction occurred in 5 patients in the ETE group (8.6%), but not in the ETS group.
    Conclusion: In preemptive kidney transplantation from living donors, urinary anastomosis can safely be performed as an end-to-side uretero-ureteral anastomosis, with low urological complications. It could prevent symptoms and complications due to native kidney obstruction.
    Level of evidence: IV.
    MeSH term(s) Humans ; Ureter/surgery ; Kidney Transplantation/adverse effects ; Retrospective Studies ; Living Donors ; Anastomosis, Surgical/adverse effects ; Postoperative Complications/etiology
    Language English
    Publishing date 2023-02-09
    Publishing country France
    Document type Journal Article
    ZDB-ID 1186190-3
    ISSN 1166-7087
    ISSN 1166-7087
    DOI 10.1016/j.purol.2023.01.003
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  4. Article: Posterior transperitoneal robot-assisted partial nephrectomy in the treatment of renal tumors: Feasibility of a hybrid approach.

    Timsit, M-O / Terrier, N / Toinet, T / Dariane, C / Debedde, E / Panthier, F / Thiounn, N / Audenet, F / Méjean, A

    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie

    2022  Volume 32, Issue 3, Page(s) 217–225

    Abstract: Purpose: Robot-assisted partial nephrectomy (RAPN) for posterior renal tumors may be performed through anterior (transperitoneal) or posterior (retroperitoneal) approach depending on surgeon's expertise. We propose herein a surgical artifice using ... ...

    Abstract Purpose: Robot-assisted partial nephrectomy (RAPN) for posterior renal tumors may be performed through anterior (transperitoneal) or posterior (retroperitoneal) approach depending on surgeon's expertise. We propose herein a surgical artifice using daVinci Xi system to combine advantages of both approaches.
    Materials and methods: From November 2019 to November 2020, patients with posterior renal mass, candidate for RAPN were prospectively included after informed consent. After positioning patient in lateral position, daVinci Xi system was docked on tumor side, to initiate transperitoneal procedure. Posterolateral dissection of perinephric space along fascia retrorenalis was conducted until psoas major muscle was exposed. Three additional robotic ports were then inserted in lumbar space, and RAPN was resumed after rotating daVinci Xi boom. Demographics, tumor characteristics, perioperative outcomes, estimated glomerular filtration rate (eGFR) and follow-up data were analyzed.
    Results: Ten consecutive patients underwent RAPN with the modified technique. All cases were performed robotically, without modification of port placement. Median (range) tumor diameter was 37 (21-48mm) with median RENAL score of 8 (4-10) Median operative time and warm ischemia time were respectively 128min (70-180min) and 19min (14-22). One patient had a Clavien-Dindo grade II complication. At median follow-up of 13 months (6-18), all patients had eGFR comparable to baseline.
    Conclusions: We report the feasibility and safety of a new hybrid posterior transperitoneal approach for RAPN using daVinci Xi system. Limitations include the absence of RENAL score>10 and pT2 tumors. Greater experience is needed to assess learning curve for surgeons untrained to robotic lomboscopy.
    MeSH term(s) Feasibility Studies ; Humans ; Kidney Neoplasms/pathology ; Nephrectomy/methods ; Robotic Surgical Procedures/methods ; Robotics/methods ; Treatment Outcome
    Language English
    Publishing date 2022-02-04
    Publishing country France
    Document type Journal Article
    ZDB-ID 1186190-3
    ISSN 1166-7087
    ISSN 1166-7087
    DOI 10.1016/j.purol.2022.01.002
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  5. Article: Ischemia-reperfusion in the renal allograft: new clues in a cold-case.

    Timsit, M-O / Kleinclauss, F

    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie

    2014  Volume 24 Suppl 1, Page(s) S1–3

    MeSH term(s) Allografts/blood supply ; Humans ; Kidney/blood supply ; Kidney Transplantation ; Reperfusion Injury
    Language English
    Publishing date 2014-06
    Publishing country France
    Document type Editorial
    ZDB-ID 1186190-3
    ISSN 1166-7087
    ISSN 1166-7087
    DOI 10.1016/S1166-7087(14)70056-9
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  6. Article: Recommandations françaises du Comité de transplantation de l’association française d’urologie (CTAFU) : agents antiplaquettaires et anticoagulants oraux directs en transplantation rénale.

    Timsit, M-O / Branchereau, J / Matillon, X / Verhoest, G / Bessede, T / LeQuintrec, M / Boissier, R / Badet, L / Smadja, D M

    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie

    2021  Volume 31, Issue 1, Page(s) 39–44

    Abstract: Objective: To define guidelines for the use of antiplatelet therapy (AT) and direct oral anticoagulants (DOAC) in candidates for kidney allotransplantation.: Method: A review of the medical literature following a systematic approach was conducted by ... ...

    Title translation Use of antiplatelet therapy and direct oral anticoagulants in candidates for renal transplantation: The French guidelines from the CTAFU.
    Abstract Objective: To define guidelines for the use of antiplatelet therapy (AT) and direct oral anticoagulants (DOAC) in candidates for kidney allotransplantation.
    Method: A review of the medical literature following a systematic approach was conducted by the CTAFU to report the use of AT and DOAC before major surgery and in the setting of advanced chronic kidney disease, defining their managment prior to kidney transplantation with the corresponding level of evidence.
    Results: DOAC are not recommended in patients under dialysis. Aspirin therapy, but not anti-P2Y
    Conclusion: These French recommendations should contribute to improve surgical management of kidney transplant candidates exposed to AT or DOA.
    MeSH term(s) Factor Xa Inhibitors/therapeutic use ; Humans ; Kidney Transplantation ; Platelet Aggregation Inhibitors/therapeutic use ; Preoperative Period
    Chemical Substances Factor Xa Inhibitors ; Platelet Aggregation Inhibitors
    Language French
    Publishing date 2021-01-09
    Publishing country France
    Document type Journal Article ; Practice Guideline ; Systematic Review
    ZDB-ID 1186190-3
    ISSN 1166-7087
    ISSN 1166-7087
    DOI 10.1016/j.purol.2020.03.015
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  7. Article: [No title information]

    Kleinclauss, F / Thuret, R / Timsit, M-O

    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie

    2016  Volume 26, Issue 15, Page(s) 872–873

    Title translation Éditorial.
    MeSH term(s) Humans ; Kidney Transplantation
    Language French
    Publishing date 2016-11
    Publishing country France
    Document type Editorial
    ZDB-ID 1186190-3
    ISSN 1166-7087
    ISSN 1166-7087
    DOI 10.1016/j.purol.2016.09.071
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  8. Article: Rendre l’âme ? D’accord, mais à qui ? disait Gainsbourg.

    Timsit, M-O / Kleinclauss, F / Thuret, R

    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie

    2016  Volume 26, Issue 15, Page(s) 871

    Title translation Give up the spirit? Fine, but whose? As Gainsbourg used to say.
    Language French
    Publishing date 2016-11
    Publishing country France
    Document type Editorial
    ZDB-ID 1186190-3
    ISSN 1166-7087
    ISSN 1166-7087
    DOI 10.1016/j.purol.2016.09.072
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  9. Article: Recommandations françaises du Comité de transplantation de l’association française d’urologie (CTAFU) : symptômes du bas appareil urinaire et incontinence urinaire chez le patient transplanté ou en attente de transplantation rénale.

    Drouin, S / Defortescu, G / Prudhomme, T / Culty, T / Verhoest, G / Doerfler, A / Goujon, A / Branchereau, J / Timsit, M-O

    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie

    2021  Volume 31, Issue 1, Page(s) 45–49

    Abstract: Objective: To propose surgical recommendations for the management of lower urinary tract symptoms (LUTS) and urinary incontinence in kidney transplant recipients and candidates.: Method: Following a systematic approach, a review of the literature ( ... ...

    Title translation Lower urinary tract symptoms and urinary incontinence in renal transplant recipients and candidates: The French guidelines from CTAFU.
    Abstract Objective: To propose surgical recommendations for the management of lower urinary tract symptoms (LUTS) and urinary incontinence in kidney transplant recipients and candidates.
    Method: Following a systematic approach, a review of the literature (Medline) was conducted by the CTAFU focusing on medical and surgical treatment of LUTS and urinary incontinence in kidney transplant recipients and candidates. References were assessed according to a predefined process to propose recommendations with levels of evidence.
    Results: Functional bladder capacity and bladder compliance are impaired during dialysis. LUTS, related to pre-kidney transplantion alterations, frequently improve spontaneously after kidney transplantation. LUTS secondary to benign prostatic hyperplasia (BPH) may be underestimated before kidney transplantation due to oliguria, low bladder compliance and low bladder capacity. In LUTS associated with BPH, anticholinergics require dosage adjustment with creatinine clearance. If surgery is indicated after kidney transplantation, procedure can be safely performed in the early post-transplant course after removal of ureteral stent. Surgical management of urinary incontinence does not seem to be associated with an icreased risk for infectious complications in kidney transplant recipients. Particular attention should be paid to the management of postvoid residual and bladder pressures in case of neurological bladder disease. Optimal care of neurological bladder should be provided prior to transplantation: with a cautious management, and despite an increased occurrence of febrile urinary tract infections, transplant survival is not compromised.
    Conclusion: These recommendations must contribute to improve the management of lower urinary tract symptoms and urinary incontinence in kidney transplant patients and kidney transplant candidates.
    MeSH term(s) Humans ; Kidney Transplantation ; Lower Urinary Tract Symptoms/complications ; Lower Urinary Tract Symptoms/surgery ; Postoperative Complications/surgery ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/surgery ; Urinary Incontinence/complications ; Urinary Incontinence/surgery
    Language French
    Publishing date 2021-01-09
    Publishing country France
    Document type Journal Article ; Practice Guideline ; Systematic Review
    ZDB-ID 1186190-3
    ISSN 1166-7087
    ISSN 1166-7087
    DOI 10.1016/j.purol.2020.03.013
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  10. Article: Sexualité, fertilité et grossesse après transplantation rénale.

    Kleinclauss, F / Timsit, M-O / Thuret, R

    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie

    2016  Volume 26, Issue 15, Page(s) 1122–1131

    Abstract: Aims: To describe sexuality and fertility alterations secondary to chronic kidney disease and their outcomes after renal transplantation.: Material and methods: An exhaustive systematic review of the scientific literature was performed in the Medline ...

    Title translation Sexuality, fertility and pregnancy after kidney transplantation.
    Abstract Aims: To describe sexuality and fertility alterations secondary to chronic kidney disease and their outcomes after renal transplantation.
    Material and methods: An exhaustive systematic review of the scientific literature was performed in the Medline database (http://www.ncbi.nlm.nih.gov) and Embase (http://www.embase.com) using different associations of the following keywords: erectile dysfunction; impotence; sexuality; pregnancy; fertility; renal transplantation. Publications obtained were selected based on methodology, language, date of publication (last 10 years) and relevance. Prospective and retrospective studies, in English or French, review articles; meta-analysis and guidelines were selected and analyzed. This search found 706 articles. After reading titles and abstracts, 76 were included in the text, based on their relevance.
    Results: The observed prevalence of erectile dysfunction is high in men with chronic kidney disease. The causes of erectile dysfunction are numbers and its origin is often multifactorial. Most of the time, kidney transplantation improves sexuality and the management of erectile dysfunction in transplanted men is similar to the general population. Improvement in sexuality in men and women after kidney transplantation may conduct to pregnancy. The outcomes of pregnancy after transplantation are quite good in absence of risk factors such as time to pregnancy less than 1 year after transplantation, uncontrolled high blood pressure, and decreased renal function of the graft. Adaptation of immunosuppression may be required to avoid any teratogenicity for the fetus.
    Conclusion: Kidney transplantation improves sexuality and fertility in men and women with chronic kidney disease.
    MeSH term(s) Female ; Humans ; Infertility/etiology ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/surgery ; Kidney Transplantation ; Male ; Pregnancy/statistics & numerical data ; Sexual Dysfunction, Physiological/etiology ; Treatment Outcome
    Language French
    Publishing date 2016-11
    Publishing country France
    Document type Journal Article ; Review
    ZDB-ID 1186190-3
    ISSN 1166-7087
    ISSN 1166-7087
    DOI 10.1016/j.purol.2016.08.014
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