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Article: Y

Zhao, Rui-Qiang / Wen, Yan / Gupta, Pranav / Lei, Zi-Ning / Cai, Chao-Yun / Liang, Gang / Yang, Dong-Hua / Chen, Zhe-Sheng / Xie, Yu-An

Frontiers in pharmacology

2019 Volume 9, Page(s) 1545

Abstract: ... Y ...

Abstract	Multidrug resistance is reported to be related to the transmembrane transportation of chemotherapeutic drugs by adenosine triphosphate-binding cassette (ABC) transporters. ABC subfamily G member 2 (ABCG2) is a member of the ABC transporter superfamily proteins, which have been implicated as a key contributor to the development of multidrug resistance in cancers. A new epigallocatechin gallate derivative, Y
Language	English
Publishing date	2019-01-10
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2587355-6
ISSN	1663-9812
ISSN	1663-9812
DOI	10.3389/fphar.2018.01545
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Correction: A Y

Wang, Yinjie / Jiang, Zhenqi / Yuan, Bo / Tian, Yuchen / Xiang, Lingchao / Li, Yanying / Yang, Yong / Li, Juan / Wu, Aiguo

Biomaterials science

2024 Volume 12, Issue 8, Page(s) 2165–2166

Abstract: Correction for 'A Y1 receptor ligand synergized with a P-glycoprotein inhibitor improves the therapeutic efficacy of multidrug resistant breast cancer' by Yinjie ... ...

Abstract	Correction for 'A Y1 receptor ligand synergized with a P-glycoprotein inhibitor improves the therapeutic efficacy of multidrug resistant breast cancer' by Yinjie Wang
Language	English
Publishing date	2024-04-16
Publishing country	England
Document type	Published Erratum
ZDB-ID	2693928-9
ISSN	2047-4849 ; 2047-4830
ISSN (online)	2047-4849
ISSN	2047-4830
DOI	10.1039/d4bm90022g
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Article ; Online: A Y

Wang, Yinjie / Jiang, Zhenqi / Yuan, Bo / Tian, Yuchen / Xiang, Lingchao / Li, Yanying / Yang, Yong / Li, Juan / Wu, Aiguo

Biomaterials science

2019 Volume 7, Issue 11, Page(s) 4748–4757

Abstract: ... to develop a novel strategy for its treatment. Based on the high overexpression of Y ...

Abstract	Multidrug resistance (MDR) is one of the main reasons for the inefficiency of cancer chemotherapy. As a consequence of MDR, the expression level of membrane proteins might be changed, which can thus be used to develop a novel strategy for its treatment. Based on the high overexpression of Y
MeSH term(s)	ATP Binding Cassette Transporter, Subfamily B, Member 1/antagonists & inhibitors ; ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism ; Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Breast Neoplasms/diagnostic imaging ; Breast Neoplasms/drug therapy ; Breast Neoplasms/metabolism ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Doxorubicin/chemistry ; Doxorubicin/pharmacology ; Drug Resistance, Multiple/drug effects ; Drug Resistance, Neoplasm/drug effects ; Drug Screening Assays, Antitumor ; Female ; Humans ; Ligands ; MCF-7 Cells ; Mammary Neoplasms, Experimental/diagnostic imaging ; Mammary Neoplasms, Experimental/drug therapy ; Mammary Neoplasms, Experimental/metabolism ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Micelles ; Nanoparticles/chemistry ; Optical Imaging ; Quinolines/chemistry ; Quinolines/pharmacology ; Receptors, Neuropeptide Y/antagonists & inhibitors ; Receptors, Neuropeptide Y/metabolism
Chemical Substances	ATP Binding Cassette Transporter, Subfamily B, Member 1 ; Antineoplastic Agents ; Ligands ; Micelles ; Quinolines ; Receptors, Neuropeptide Y ; Doxorubicin (80168379AG) ; tariquidar (J58862DTVD)
Language	English
Publishing date	2019-09-11
Publishing country	England
Document type	Journal Article
ZDB-ID	2693928-9
ISSN	2047-4849 ; 2047-4830
ISSN (online)	2047-4849
ISSN	2047-4830
DOI	10.1039/c9bm00337a
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The Neuropeptide Y

Wang, Yinjie / Cao, Yi / Jiang, Zhenqi / Li, Yanying / Yuan, Bo / Xing, Jie / Li, Mingli / Gao, Qianqian / Xu, Kaiwei / Akakuru, Ozioma Udochukwu / Wu, Aiguo / Li, Juan

The journal of physical chemistry letters

2021 Volume 12, Issue 46, Page(s) 11280–11287

Abstract: ... nanovehicles, a neuropeptide Y ...

Abstract	Zeolitic imidazolate frameworks (ZIFs), widely regarded as promising materials for application in catalysis and separation, hold an increasingly significant position in drug delivery systems for their high drug loading capacity. Focused specifically on the rational design of targeting and bioresponsive nanovehicles, a neuropeptide Y
MeSH term(s)	Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Breast Neoplasms/drug therapy ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Cell Membrane/drug effects ; Cerium/chemistry ; Cerium/pharmacology ; Humans ; Imidazoles/chemistry ; Imidazoles/pharmacology ; Ligands ; MCF-7 Cells ; Photochemotherapy ; Photosensitizing Agents/chemistry ; Photosensitizing Agents/pharmacology ; Receptors, Neuropeptide Y/antagonists & inhibitors ; Receptors, Neuropeptide Y/metabolism ; Zeolites/chemistry ; Zeolites/pharmacology
Chemical Substances	Antineoplastic Agents ; Imidazoles ; Ligands ; Photosensitizing Agents ; Receptors, Neuropeptide Y ; neuropeptide Y-Y1 receptor ; Zeolites (1318-02-1) ; Cerium (30K4522N6T)
Language	English
Publishing date	2021-11-12
Publishing country	United States
Document type	Journal Article
ISSN	1948-7185
ISSN (online)	1948-7185
DOI	10.1021/acs.jpclett.1c03562
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Reply to Y. Yu et al.

Raghav, Kanwal / Kopetz, Scott / Yuan, Ying

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

2023 Volume 41, Issue 7, Page(s) 1495–1496

Language	English
Publishing date	2023-01-03
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Comment
ZDB-ID	604914-x
ISSN	1527-7755 ; 0732-183X
ISSN (online)	1527-7755
ISSN	0732-183X
DOI	10.1200/JCO.22.02588
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Zs.A 1847: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 650: Show issues

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Article ; Online: Polycrystalline Er-doped Y

Yu, Zhimin / Yuan, Kang / Yang, Yang / Sun, Jiaming

Nanoscale

2022 Volume 14, Issue 29, Page(s) 10540–10548

Abstract: Polycrystalline erbium-doped Y ...

Abstract	Polycrystalline erbium-doped Y
Language	English
Publishing date	2022-07-28
Publishing country	England
Document type	Journal Article
ZDB-ID	2515664-0
ISSN	2040-3372 ; 2040-3364
ISSN (online)	2040-3372
ISSN	2040-3364
DOI	10.1039/d2nr03118c
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Article ; Online: Leptospira-specific immunoglobulin Y (IgY) is protective in infected hamsters.

Lv, Tianbao / Xie, Xufeng / Diao, Luteng / Jiang, Shuang / Ding, Yue / Yuan, Xin / Gong, Lingling / Chen, Xi / Zhang, Wenlong / Cao, Yongguo

Vaccine

2024 Volume 42, Issue 13, Page(s) 3220–3229

Abstract: Leptospirosis, a globally significant zoonotic disease caused by pathogenic Leptospira, continues to threaten the health and public safety of both humans and animals. Current clinical treatment of leptospirosis mainly relies on antibiotics but their ... ...

Abstract	Leptospirosis, a globally significant zoonotic disease caused by pathogenic Leptospira, continues to threaten the health and public safety of both humans and animals. Current clinical treatment of leptospirosis mainly relies on antibiotics but their efficacy in severe cases is controversial. Passive immunization has a protective effect in the treatment of infectious diseases. In addition, chicken egg yolk antibody (IgY) has gained increasing attention as a safe passive immunization agent. This study aimed to investigate whether hens produce specific IgY after immunization with inactivated Leptospira and the protective effect of specific IgY against leptospirosis. First, it was demonstrated that specific IgY could be extracted from the eggs of hens vaccinated with inactivated Leptospira and that specific IgY can specifically recognize and bind homotypic Leptospira with a high titre, as shown by MAT and ELISA. Next, we tested the therapeutic effects of IgY in early and late leptospirosis using a hamster model. The results showed that early specific IgY treatment increased the survival rate of hamsters to 100%, alleviated pathological damage to the liver, kidney, and lung, reduced leptospiral burden, and restored haematological indices as well as functional indicators of the liver and kidney. The therapeutic effect of early specific IgY was comparable to that of doxycycline. Late IgY treatment also enhanced the survival rate of hamsters and improved the symptoms of leptospirosis similar to early IgY treatment. However, the therapeutic effect of late IgY treatment was better when combined with doxycycline. Furthermore, no Leptospira colonization was observed in the kidneys, livers, or lungs of the surviving hamsters treated with specific IgY. Mechanistically, IgY was found to inhibit the growth and adhesion to cells of Leptospira. In conclusion, passive immunotherapy with specific IgY can be considered an effective treatment for leptospirosis, and may replace antibiotics regarding its therapeutic effects.
MeSH term(s)	Animals ; Leptospirosis/immunology ; Leptospirosis/prevention & control ; Leptospirosis/therapy ; Immunoglobulins/immunology ; Immunoglobulins/administration & dosage ; Leptospira/immunology ; Cricetinae ; Chickens/immunology ; Immunization, Passive/methods ; Antibodies, Bacterial/immunology ; Female ; Disease Models, Animal ; Kidney/pathology ; Kidney/immunology ; Kidney/microbiology ; Doxycycline/therapeutic use ; Doxycycline/administration & dosage ; Doxycycline/pharmacology ; Vaccines, Inactivated/immunology ; Vaccines, Inactivated/administration & dosage ; Mesocricetus ; Egg Yolk/immunology ; Liver/immunology ; Liver/pathology ; Liver/microbiology
Chemical Substances	IgY ; Immunoglobulins ; Antibodies, Bacterial ; Doxycycline (N12000U13O) ; Vaccines, Inactivated
Language	English
Publishing date	2024-04-18
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	605674-x
ISSN	1873-2518 ; 0264-410X
ISSN (online)	1873-2518
ISSN	0264-410X
DOI	10.1016/j.vaccine.2024.04.010
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Zs.A 1930: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 458: Show issues

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Article ; Online: Defect Regulation of Terbium-Doped Y

Lu, Kailei / Ye, Yucheng / Han, Wenhan / Zhang, Cong / Liang, Lexing / Yuan, Haifeng / Shi, Yanli / Qi, Jianqi / Lu, Tiecheng

The journal of physical chemistry letters

2022 Volume 13, Issue 34, Page(s) 8097–8103

Abstract: ... their applications. Herein, a transparent Y ...

Abstract	In the most promising new window materials, the light-blocking property of the state-of-the-art transparent polycrystalline ceramics is still located in the UV range, which undoubtedly limits their applications. Herein, a transparent Y
Language	English
Publishing date	2022-08-23
Publishing country	United States
Document type	Journal Article
ISSN	1948-7185
ISSN (online)	1948-7185
DOI	10.1021/acs.jpclett.2c02177
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Article ; Online: A D-Y Shaped Neuropeptide Y Mimetic Peptide-Dye Self-Assembly with Maximal Emission Beyond 1300 nm and Glioma Mitochondrial Activity Modulation.

Li, Yanying / He, Xuelu / Wang, Pin / Yuan, Bo / Pan, Yuanbo / Hu, Xueyin / Lu, Liheng / Wu, Aiguo / Li, Juan

Small (Weinheim an der Bergstrasse, Germany)

2023 Volume 20, Issue 13, Page(s) e2308621

Abstract: Neuropeptide Y (NPY), as one of the most abundant neuropeptides known, is widely distributed ...

Abstract	Neuropeptide Y (NPY), as one of the most abundant neuropeptides known, is widely distributed in the central and peripheral nervous system. However, most of the reported NPY-mimetic peptides are hard to cross the blood-brain barrier, target glioma mitochondria, and achieve self-assembly nanostructure in situ. Here, based on the α-helix structure of the novel chiral NPY-mimetic peptides
MeSH term(s)	Neuropeptide Y ; Receptors, Neuropeptide Y/metabolism ; Blood-Brain Barrier/metabolism
Chemical Substances	Neuropeptide Y ; Receptors, Neuropeptide Y
Language	English
Publishing date	2023-12-18
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2168935-0
ISSN	1613-6829 ; 1613-6810
ISSN (online)	1613-6829
ISSN	1613-6810
DOI	10.1002/smll.202308621
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Article ; Online: The composition of Tibetan kefir grain TKG-Y and the antibacterial potential and milk fermentation ability of

Guo, Xing / He, Yining / Cheng, Yifan / Liang, Jingyimei / Xu, Pandi / He, Wenwen / Che, Jiayin / Men, Jiexing / Yuan, Yahong / Yue, Tianli

Food & function

2024

Abstract: ... composition of a Tibetan herder's homemade kefir grain named TKG-Y. Subsequently, ...

Abstract	This study utilized high-throughput sequencing and SEM observation to elucidate the microbial composition of a Tibetan herder's homemade kefir grain named TKG-Y. Subsequently,
Language	English
Publishing date	2024-04-23
Publishing country	England
Document type	Journal Article
ZDB-ID	2612033-1
ISSN	2042-650X ; 2042-6496
ISSN (online)	2042-650X
ISSN	2042-6496
DOI	10.1039/d4fo00112e
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Z 7872: Show issues

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