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  1. Article ; Online: Tracking

    Morrison, Blair H / Jones, Jessica L / Dzwonkowski, Brian / Krause, Jeffrey W

    Microbiology spectrum

    2024  , Page(s) e0367423

    Abstract: Vibrio: Importance: ... ...

    Abstract Vibrio
    Importance: Vibrio
    Language English
    Publishing date 2024-04-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.03674-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Development of trofinetide for the treatment of Rett syndrome: from bench to bedside.

    Kennedy, Melissa / Glass, Larry / Glaze, Daniel G / Kaminsky, Steve / Percy, Alan K / Neul, Jeffrey L / Jones, Nancy E / Tropea, Daniela / Horrigan, Joseph P / Nues, Paige / Bishop, Kathie M / Youakim, James M

    Frontiers in pharmacology

    2024  Volume 14, Page(s) 1341746

    Abstract: Rett syndrome (RTT) is rare neurodevelopmental disorder caused by mutations in ... ...

    Abstract Rett syndrome (RTT) is rare neurodevelopmental disorder caused by mutations in the
    Language English
    Publishing date 2024-01-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1341746
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Characterization of disease burden, treatment and comorbidities in a large, real-world cohort of patients with atopic dermatitis: The CorEvitas Atopic Dermatitis Registry.

    Silverberg, Jonathan I / Cronin, Angel / Jones, Eric A / Dave, Swapna S / McLean, Robert R / Greenberg, Jeffrey / Strober, Bruce / Bieber, Thomas / Gooderham, Melinda / Paller, Amy S / Simpson, Eric L

    JAAD international

    2024  Volume 15, Page(s) 127–130

    Language English
    Publishing date 2024-02-12
    Publishing country United States
    Document type Journal Article
    ISSN 2666-3287
    ISSN (online) 2666-3287
    DOI 10.1016/j.jdin.2023.11.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Elucidating the Mode of Action of Hybrid Nanoparticles of Cu/Zn against Copper Tolerant

    Carvalho, Renato / Tapia, Jose H / Minsavage, Gerald V / Jones, Jeffrey B / Paret, Mathews L

    Phytopathology

    2024  

    Abstract: The widespread presence of tolerance to copper in Xanthomonas species has resulted in the need to develop alternative approaches to control plant diseases caused by xanthomonads. In recent years, nanotechnological approaches have resulted in the ... ...

    Abstract The widespread presence of tolerance to copper in Xanthomonas species has resulted in the need to develop alternative approaches to control plant diseases caused by xanthomonads. In recent years, nanotechnological approaches have resulted in the identification of novel materials to control plant pathogens. While many metal-based nanomaterials have shown promise for disease control, an important question relates to the mode of action of these new materials. In this study we used several approaches such as SEM, propidium monoazide qPCR, epifluorescence microscopy and RNA sequencing to elucidate the mode of action of a Cu/Zn hybrid nanoparticle against copper tolerant strains of Xanthomonas euvesicatoria. We demonstrate that Cu/Zn, unlike Kocide 3000, did not activate copper resistance genes (i.e. copA and copB) in the copper-tolerant bacterium, but functioned by disrupting the bacterial cell structure and perturbing important biological processes such as cell respiration and chemical homeostasis.
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208889-7
    ISSN 1943-7684 ; 0031-949X
    ISSN (online) 1943-7684
    ISSN 0031-949X
    DOI 10.1094/PHYTO-09-23-0339-R
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 698: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: A curious case to keep you awake at night.

    Lynch, Joseph D / Lancaster, Jeffrey / Jones, Yemisi O / Andrews, Annie L

    Journal of hospital medicine

    2022  Volume 18, Issue 3, Page(s) 262–266

    Language English
    Publishing date 2022-09-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2233783-0
    ISSN 1553-5606 ; 1553-5592
    ISSN (online) 1553-5606
    ISSN 1553-5592
    DOI 10.1002/jhm.12970
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6276: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 542: Show issues

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  6. Article: Whole-Genome-Sequence-Based Classification of

    Choudhary, Manoj / Minsavage, Gerald V / Goss, Erica M / Timilsina, Sujan / Coutinho, Teresa A / Vallad, Gary E / Paret, Mathews L / Jones, Jeffrey B

    Phytopathology

    2024  Volume 114, Issue 1, Page(s) 47–60

    Abstract: ... ...

    Abstract Xanthomonas
    MeSH term(s) Type III Secretion Systems ; Phylogeny ; Eucalyptus ; Plant Diseases/microbiology ; Xanthomonas
    Chemical Substances Type III Secretion Systems
    Language English
    Publishing date 2024-02-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208889-7
    ISSN 1943-7684 ; 0031-949X
    ISSN (online) 1943-7684
    ISSN 0031-949X
    DOI 10.1094/PHYTO-05-23-0150-R
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 698: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Non-coding deep learning models for tomato biotic and abiotic stress classification using microscopic images.

    Choudhary, Manoj / Sentil, Sruthi / Jones, Jeffrey B / Paret, Mathews L

    Frontiers in plant science

    2023  Volume 14, Page(s) 1292643

    Abstract: Plant disease classification is quite complex and, in most cases, requires trained plant pathologists and sophisticated labs to accurately determine the cause. Our group for the first time used microscopic images (×30) of tomato plant diseases, for which ...

    Abstract Plant disease classification is quite complex and, in most cases, requires trained plant pathologists and sophisticated labs to accurately determine the cause. Our group for the first time used microscopic images (×30) of tomato plant diseases, for which representative plant samples were diagnostically validated to classify disease symptoms using non-coding deep learning platforms (NCDL). The mean F1 scores (SD) of the NCDL platforms were 98.5 (1.6) for Amazon Rekognition Custom Label, 93.9 (2.5) for Clarifai, 91.6 (3.9) for Teachable Machine, 95.0 (1.9) for Google AutoML Vision, and 97.5 (2.7) for Microsoft Azure Custom Vision. The accuracy of the NCDL platform for Amazon Rekognition Custom Label was 99.8% (0.2), for Clarifai 98.7% (0.5), for Teachable Machine 98.3% (0.4), for Google AutoML Vision 98.9% (0.6), and for Apple CreateML 87.3 (4.3). Upon external validation, the model's accuracy of the tested NCDL platforms dropped no more than 7%. The potential future use for these models includes the development of mobile- and web-based applications for the classification of plant diseases and integration with a disease management advisory system. The NCDL models also have the potential to improve the early triage of symptomatic plant samples into classes that may save time in diagnostic lab sample processing.
    Language English
    Publishing date 2023-01-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2023.1292643
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Erratum for Foxall et al., "

    Foxall, Randi L / Means, Jillian / Marcinkiewicz, Ashley L / Schillaci, Christopher / DeRosia-Banick, Kristin / Xu, Feng / Hall, Jeffrey A / Jones, Stephen H / Cooper, Vaughn S / Whistler, Cheryl A

    mBio

    2024  , Page(s) e0102024

    Language English
    Publishing date 2024-04-22
    Publishing country United States
    Document type Journal Article ; Published Erratum
    ZDB-ID 2557172-2
    ISSN 2150-7511 ; 2161-2129
    ISSN (online) 2150-7511
    ISSN 2161-2129
    DOI 10.1128/mbio.01020-24
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Quantitative Analysis of Autophagy in Single Cells: Differential Response to Amino Acid and Glucose Starvation.

    Martin, Katie R / Celano, Stephanie L / Sheldon, Ryan D / Jones, Russell G / MacKeigan, Jeffrey P

    bioRxiv : the preprint server for biology

    2023  

    Abstract: Autophagy is a highly conserved, intracellular recycling process by which cytoplasmic contents are degraded in the lysosome. This process occurs at a low level constitutively; however, it is induced robustly in response to stressors, in particular, ... ...

    Abstract Autophagy is a highly conserved, intracellular recycling process by which cytoplasmic contents are degraded in the lysosome. This process occurs at a low level constitutively; however, it is induced robustly in response to stressors, in particular, starvation of critical nutrients such as amino acids and glucose. That said, the relative contribution of these inputs is ambiguous and many starvation medias are poorly defined or devoid of multiple nutrients. Here, we sought to generate a quantitative catalog of autophagy across multiple stages and in single, living cells under normal growth conditions as well as in media starved specifically of amino acids or glucose. We found that autophagy is induced by starvation of amino acids, but not glucose, in U2OS cells, and that MTORC1-mediated ULK1 regulation and autophagy are tightly linked to amino acid levels. While autophagy is engaged immediately during amino acid starvation, a heightened response occurs during a period marked by transcriptional upregulation of autophagy genes during sustained starvation. Finally, we demonstrated that cells immediately return to their initial, low-autophagy state when nutrients are restored, highlighting the dynamic relationship between autophagy and environmental conditions. In addition to sharing our findings here, we provide our data as a high-quality resource for others interested in mathematical modeling or otherwise exploring autophagy in individual cells across a population.
    Language English
    Publishing date 2023-12-03
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.12.01.569679
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Limited evidence that asymmetries of multiple Whiskered Auklet (Aethia pygmaea) feather ornaments could serve a display function

    Jones, Ian L. / Hunter, Fiona M. / Seneviratne, Sampath S. / Williams, Jeffrey C. / Montgomerie, Robert

    Ibis. 2023 Oct., v. 165, no. 4 p.1343-1358

    2023  

    Abstract: ... but variation in asymmetries was large and differences between left (L) and right (R) sides in most birds were ... probably too small to be detected visually. Marginal mean absolute asymmetries (|L–R|) of super‐ and ...

    Abstract Elaborate avian feather ornaments have proven to be enigmatic because their function is often unclear, even though they are used in courtship and social displays. Male and female Whiskered Auklets Aethia pygmaea display on their faces four elaborate feather ornaments that serve both courtship and mechanosensory functions: three bilateral pairs of white facial plume tracts (superorbital, suborbital and auricular) and a slender black forehead crest, each consisting of several filoplumes. We studied left–right symmetry in the three antenna‐like bilateral white head plumes of 721 wild‐caught marked individuals (162 of known sex, 94 of known age that were 1–16 years old) during 1992–2009. Auricular and suborbital plumes were slightly more asymmetric in subadults (1‐year‐olds) than in adults (≥ 2 years old) but the opposite was true for superorbital plumes. Ornament asymmetries were not sexually dimorphic, nor were they significantly related to individual body condition, body size or age, except that superorbital plume asymmetry decreased significantly with tarsus length. Relative asymmetry (scaled for ornament size) of all three ornaments was negatively correlated with plume size, as predicted by some sexual selection models, but variation in asymmetries was large and differences between left (L) and right (R) sides in most birds were probably too small to be detected visually. Marginal mean absolute asymmetries (|L–R|) of super‐ and suborbital plumes were correlated with ocean climate during the preceding year when the birds would have been moulting, suggesting that fluctuating asymmetry at the population level might be a useful index of environmental stress in this seabird. The spectacular bilaterally expressed facial plumes displayed by Whiskered Auklets provide an interesting test case for questions about asymmetry in sexually and naturally selected traits.
    Keywords asymmetry ; body condition ; body size ; climate ; courtship ; females ; head ; males ; seabirds ; sexual dimorphism ; sexual selection
    Language English
    Dates of publication 2023-10
    Size p. 1343-1358.
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 2071870-6
    ISSN 1474-919X ; 0019-1019
    ISSN (online) 1474-919X
    ISSN 0019-1019
    DOI 10.1111/ibi.13214
    Database NAL-Catalogue (AGRICOLA)

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