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Article: Comparative assessment of two circularity indicators for the case of reusable versus single-use secondary packages for fresh foods in Spain.

Sazdovski, Ilija / Batlle-Bayer, Laura / Bala, Alba / Margallo, Maria / Azarkamand, Sahar / Aldaco, Ruben / Fullana-I-Palmer, Pere

Heliyon

2024 Volume 10, Issue 6, Page(s) e27922

Abstract: Sustainable packaging is a crucial focus in the context of circular economy efforts. This study evaluates the circularity of two secondary packaging systems used in Spanish fresh food produces: Reusable Plastic Crates and Single-use Cardboard Boxes. A ... ...

Abstract	Sustainable packaging is a crucial focus in the context of circular economy efforts. This study evaluates the circularity of two secondary packaging systems used in Spanish fresh food produces: Reusable Plastic Crates and Single-use Cardboard Boxes. A Mass Flow Analysis was performed to assess the material flows in the production and use phases of both systems and two circular indicators were applied: the Material Circularity Indicator and Product Circular Indicator. While most previous studies for single-use packaging use these indicators at the product level, this study applies a system approach since the Reusable Plastic Crates can be reused 100 times. The functional unit was defined as the distribution of 1000 tonnes of fresh products, resulting in the distribution of 6,666,700 packages with 15 kg of products. The Material Circularity Indicator and Product Circular Indicator results show that Reusable Plastic Crates are more circular than Single-use Cardboard Boxes. The Product Circular Indicator provides a more comprehensive assessment of circularity by considering multiple life cycle stages, efficiency, and unrecoverable waste, resulting in a difference in circularity evaluations. The indicators used have limitations as they do not consider the resource stock. Further research is needed to explore this aspect.
Language	English
Publishing date	2024-03-12
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2024.e27922
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Article ; Online: Carbon accounting of negative emissions technologies integrated in the life cycle of spirulina supplements.

Fernández-Ríos, Ana / Butnar, Isabela / Margallo, María / Laso, Jara / Borrion, Aiduan / Aldaco, Rubén

The Science of the total environment

2023 Volume 890, Page(s) 164362

Abstract: Carbon dioxide removal (CDR) technologies are considered essential to accomplish the Paris Agreement targets. Given the important contribution of the food sector to climate change, this study aims to investigate the role of two carbon capture and ... ...

Abstract	Carbon dioxide removal (CDR) technologies are considered essential to accomplish the Paris Agreement targets. Given the important contribution of the food sector to climate change, this study aims to investigate the role of two carbon capture and utilization (CCU) technologies in decarbonizing the production of spirulina, an algae product commonly consumed for its nutritional characteristics. The proposed scenarios considered the replacement of synthetic food-grade CO
MeSH term(s)	Animals ; Carbon Dioxide/analysis ; Spirulina ; Greenhouse Gases ; Dietary Supplements ; Life Cycle Stages ; Greenhouse Effect
Chemical Substances	Carbon Dioxide (142M471B3J) ; Greenhouse Gases
Language	English
Publishing date	2023-05-23
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2023.164362
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Article ; Online: Environmental assessment of food and beverage under a NEXUS Water-Energy-Climate approach: Application to the spirit drinks.

Leivas, R / Laso, J / Abejón, R / Margallo, M / Aldaco, R

The Science of the total environment

2020 Volume 720, Page(s) 137576

Abstract: The energy-water nexus is a concept widely established but rarely applied to product and, in particular, to food and beverage products, which have a great influence on greenhouse gases emissions. The proposed method considers the main nexus aspects in ... ...

Abstract	The energy-water nexus is a concept widely established but rarely applied to product and, in particular, to food and beverage products, which have a great influence on greenhouse gases emissions. The proposed method considers the main nexus aspects in addition to other relevant aspects such as climate change, which is deeply linked with energy and water systems, and assessing process as well as product. In this framework, this study develops an integrated index (I
MeSH term(s)	Beverages ; Climate Change ; Food ; Water ; Water Supply
Chemical Substances	Water (059QF0KO0R)
Language	English
Publishing date	2020-02-26
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2020.137576
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Article: Differential distribution of gene polymorphisms associated with hypercholesterolemia, hypertriglyceridemia, and hypoalphalipoproteinemia among Native American and Mestizo Mexicans.

Torres-Valadez, Rafael / Roman, Sonia / Ojeda-Granados, Claudia / Gonzalez-Aldaco, Karina / Panduro, Arturo

World journal of hepatology

2022 Volume 14, Issue 7, Page(s) 1408–1420

Abstract: Background: Dyslipidemias are metabolic abnormalities associated with chronic diseases caused by genetic and environmental factors. The Mexican population displays regional differences according to ethnicity with an impact on the type of dyslipidemia.!## ...

Abstract	Background: Dyslipidemias are metabolic abnormalities associated with chronic diseases caused by genetic and environmental factors. The Mexican population displays regional differences according to ethnicity with an impact on the type of dyslipidemia. Aim: To define the main dyslipidemias, the frequency of lipid-related risk alleles, and their association with hyperlipidemic states among different ethnic groups in West Mexico. Methods: In a retrospective study, 1324 adults were selected to compare dyslipidemias and lipid-related gene polymorphisms. Demographic, clinical, and laboratory data were collected. A subgroup of 196 normal weight subjects without impaired glucose was selected for the association analyses. Genotyping was determined by allelic discrimination assay. Results: Hypercholesterolemia was the most prevalent dyslipidemia (42.3%). The frequency of the risk alleles associated with hypoalphalipoproteinemia ( Conclusion: Gene polymorphisms and dyslipidemias showed a differential distribution. Regional primary health care strategies are required to mitigate their prevalence considering the genetic and environmental features which could have important implications for personalized medicine within the new era of precision medicine.
Language	English
Publishing date	2022-09-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	2573703-X
ISSN	1948-5182
ISSN	1948-5182
DOI	10.4254/wjh.v14.i7.1408
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Article ; Online: Environmental performance of Cantabrian (Northern Spain) pelagic fisheries: Assessment of purse seine and minor art fleets under a life cycle approach.

Ceballos-Santos, Sandra / Laso, Jara / Ulloa, Laura / Ruiz Salmón, Israel / Margallo, María / Aldaco, Rubén

The Science of the total environment

2022 Volume 855, Page(s) 158884

Abstract: The perpetuation of fishing activity from an environmentally, socially and economically sustainable approach is essential to guarantee not only the future of coastal populations, but also the supply of high-value seafood for society and the safeguarding ... ...

Abstract	The perpetuation of fishing activity from an environmentally, socially and economically sustainable approach is essential to guarantee not only the future of coastal populations, but also the supply of high-value seafood for society and the safeguarding of cultural heritage. This article aims to assess the environmental performance associated with fishing fleet operations in Cantabria (northern Spain) under a life cycle thinking from a holistic approach. Thus, the Life Cycle Assessment (LCA) methodology was applied under a 'cradle-to-port' approach, setting the functional unit as 1 kg of fresh fish landed. Inventory data on the main inputs and outputs were collected from a sample of 57 vessels covering for the first time the main techniques, purse seine and minor art fisheries. The results identified that the vessel use stage was the responsible of most of the impacts. In line with the literature, diesel consumption stood as the chief hotspot in six of the seven impact categories analysed. Purse seiners got a value of 0.25 kg of fuel per kg of fish landed, while the performance of the minor art fleet showed significantly lower consumption (0.07). Regarding impacts on climate change, this study found a quantity of 1.00 and 0.34 kg CO
MeSH term(s)	Animals ; Fisheries ; Spain ; Life Cycle Stages
Language	English
Publishing date	2022-09-20
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2022.158884
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Article: Environmental and Yield Comparison of Quick Extraction Methods for Caffeine and Chlorogenic Acid from Spent Coffee Grounds.

Bouhzam, Ibtissam / Cantero, Rosa / Balcells, Mercè / Margallo, María / Aldaco, Rubén / Bala, Alba / Fullana-I-Palmer, Pere / Puig, Rita

Foods (Basel, Switzerland)

2023 Volume 12, Issue 4

Abstract: This study aims to provide an overview of different extraction methods to obtain chlorogenic acid (CA) and caffeine (Caf) from spent coffee grounds (SCG). This overview shows that the quantity extracted is highly dependent on the type of SCG, so ... ...

Abstract	This study aims to provide an overview of different extraction methods to obtain chlorogenic acid (CA) and caffeine (Caf) from spent coffee grounds (SCG). This overview shows that the quantity extracted is highly dependent on the type of SCG, so experiments using the same SCG are needed to compare different methods. Three easy and simple extraction methods will be tested at a laboratory scale and environmentally compared. All three experiments were of 1 min duration: first, using supramolecular solvent; second, with water and vortex; and third, with water assisted by ultrasound. Water extraction assisted by ultrasound at room temperature yielded the greatest quantity of chlorogenic acid and caffeine, with 1.15 mg CA/g and 0.972 mg Caf/g, respectively. Extraction using supra-solvent leads to a lower content of CA in the supra-phase since it has more affinity for the water-based inferior phase. An environmental assessment using life cycle assessment has been carried out to compare water and supra extraction methods for the manufacture of two different commercial products: a face cream and an eye contour serum. Results show that the type of solvent and the amount of active substance extracted have a great influence on the environmental results. The results presented here are important for companies willing to obtain these active substances at an industrial scale.
Language	English
Publishing date	2023-02-10
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2704223-6
ISSN	2304-8158
ISSN	2304-8158
DOI	10.3390/foods12040779
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Article: Extraction of Bioactive Compounds from Spent Coffee Grounds Using Ethanol and Acetone Aqueous Solutions.

Bouhzam, Ibtissam / Cantero, Rosa / Margallo, María / Aldaco, Rubén / Bala, Alba / Fullana-I-Palmer, Pere / Puig, Rita

Foods (Basel, Switzerland)

2023 Volume 12, Issue 24

Abstract: Given global coffee consumption, substantial quantities of spent coffee grounds (SCGs) are generated annually as a by-product of brewing coffee. SCG, although rich in bioactive compounds, is nowadays disposed of. The objective of this study is to compare, ...

Abstract	Given global coffee consumption, substantial quantities of spent coffee grounds (SCGs) are generated annually as a by-product of brewing coffee. SCG, although rich in bioactive compounds, is nowadays disposed of. The objective of this study is to compare, for the first time and from the same SCG, the efficiency of ethanol-water mixtures and acetone-water mixtures for the recovery of total polyphenols, chlorogenic acid, and caffeine. Acetone at 20% (m/m) was the most convenient solvent to extract all three bioactive compounds simultaneously, yielding 4.37 mg of GAE/g SCG for total polyphenols, chlorogenic acid (0.832 mg 5-CQA/g SCG), and caffeine (1.47 mg/g SCG). Additionally, this study aims to address some challenges associated with the industrial-scale utilization of SCG as a raw material, encompassing factors such as pre-treatment conditions (natural drying and oven drying), storage duration, and the kinetics of the extraction process. No significant difference was observed between the natural drying and oven drying of SCG. In terms of storage duration, it is advisable to process the SCG within less than 3-4 months of storage time. A significant decline of 82% and 70% in chlorogenic acid (5-CQA) and caffeine contents, respectively, was observed after eight months of storage. Furthermore, the kinetic study for the recovery of total polyphenols revealed that the optimal extraction times were 10 min for acetone at 20% and 40 min for water, with a yield increase of 28% and 34%, respectively. What is remarkable from the present study is the approach considered, using the simplest operating conditions (minimal time and solvent-to-solid ratio, and ambient temperature); hence, at an industrial scale, energy and resource consumption and equipment dimensions can be together reduced, leading to a more industrially sustainable extraction process.
Language	English
Publishing date	2023-12-07
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2704223-6
ISSN	2304-8158
ISSN	2304-8158
DOI	10.3390/foods12244400
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Article ; Online: TDP2 is a regulator of estrogen-responsive oncogene expression.

Manguso, Nicholas / Kim, Minhyung / Joshi, Neeraj / Al Mahmud, Md Rasel / Aldaco, Juan / Suzuki, Ryusuke / Cortes-Ledesma, Felipe / Cui, Xiaojiang / Yamada, Shintaro / Takeda, Shunichi / Giuliano, Armando / You, Sungyong / Tanaka, Hisashi

NAR cancer

2024 Volume 6, Issue 2, Page(s) zcae016

Abstract: With its ligand estrogen, the estrogen receptor (ER) initiates a global transcriptional program, promoting cell growth. This process involves topoisomerase 2 (TOP2), a key protein in resolving topological issues during transcription by cleaving a DNA ... ...

Abstract	With its ligand estrogen, the estrogen receptor (ER) initiates a global transcriptional program, promoting cell growth. This process involves topoisomerase 2 (TOP2), a key protein in resolving topological issues during transcription by cleaving a DNA duplex, passing another duplex through the break, and repairing the break. Recent studies revealed the involvement of various DNA repair proteins in the repair of TOP2-induced breaks, suggesting potential alternative repair pathways in cases where TOP2 is halted after cleavage. However, the contribution of these proteins in ER-induced transcriptional regulation remains unclear. We investigated the role of tyrosyl-DNA phosphodiesterase 2 (TDP2), an enzyme for the removal of halted TOP2 from the DNA ends, in the estrogen-induced transcriptome using both targeted and global transcription analyses.
Language	English
Publishing date	2024-04-08
Publishing country	England
Document type	Journal Article
ISSN	2632-8674
ISSN (online)	2632-8674
DOI	10.1093/narcan/zcae016
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Article ; Online: The fishing and seafood sector in the time of COVID-19: Considerations for local and global opportunities and responses.

Ruiz-Salmón, Israel / Fernández-Ríos, Ana / Campos, Cristina / Laso, Jara / Margallo, María / Aldaco, Rubén

Current opinion in environmental science & health

2021 Volume 23, Page(s) 100286

Abstract: This article provides an overview of the impact of the COVID-19 pandemic on the fishing sector over the world, including several economic, social, environmental, and health challenges that the fisheries have had to face during the early days of the ... ...

Abstract	This article provides an overview of the impact of the COVID-19 pandemic on the fishing sector over the world, including several economic, social, environmental, and health challenges that the fisheries have had to face during the early days of the health crisis, and some of them still continue today. These problems, in short, are translated into a decrease in seafood demand, loss of jobs, changes in food consumption habits, economic losses, or increased vulnerability of the industry. As a consequence, governments have been forced to implement regulations and measures in support of this sector. However, a positive aspect of the pandemic also stands out, the opportunity to transform the food system to be greener, more inclusive, and resilient against future shocks.
Language	English
Publishing date	2021-06-24
Publishing country	Netherlands
Document type	Journal Article ; Review
ISSN	2468-5844
ISSN (online)	2468-5844
DOI	10.1016/j.coesh.2021.100286
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Article ; Online: Techno-economic and environmental assessment of methane oxidation layer measures through small-scale clean development mechanism - The case of the Seychelles.

Cristóbal, Jorge / Sierra, Luis / Margallo, María / Kannengießer, Jan / Aldaco, Rubén / Schebek, Liselotte / Irabien, Ángel

Waste management (New York, N.Y.)

2021 Volume 124, Page(s) 244–253

Abstract: Unclosed coastal landfills in small island developing states are major sources of greenhouse gases and other environmental impacts. This is a major problem for sustainable waste management systems mainly due to the lack of economic resources. The clean ... ...

Abstract	Unclosed coastal landfills in small island developing states are major sources of greenhouse gases and other environmental impacts. This is a major problem for sustainable waste management systems mainly due to the lack of economic resources. The clean development mechanism (CDM) appears as a possibility to facilitate sustainable financing. Implementing a methane oxidation layer (MOL) emerges as a feasible technical option for this kind of small landfills since landfill gas extraction is usually not viable. This paper presents a techno-economic and environmental assessment of MOL implementation in the Providence landfill (Seychelles) as a small-scale CDM measure. Results show that the MOL measure could avoid by 2030 between 94 and 20 kt CO
MeSH term(s)	Air Pollutants/analysis ; Environmental Monitoring ; Methane/analysis ; Paris ; Refuse Disposal ; Seychelles ; Waste Disposal Facilities
Chemical Substances	Air Pollutants ; Methane (OP0UW79H66)
Language	English
Publishing date	2021-02-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	2001471-5
ISSN	1879-2456 ; 0956-053X
ISSN (online)	1879-2456
ISSN	0956-053X
DOI	10.1016/j.wasman.2021.02.005
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