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  1. Book ; Online: Freezing Fertility

    van de Wiel, Lucy

    Oocyte Cryopreservation and the Gender Politics of Aging

    (Biopolitics: medicine, technoscience, and health in the twenty-first century series)

    2020  

    Series title Biopolitics: medicine, technoscience, and health in the twenty-first century series
    Keywords Health & personal development ; Human reproduction, growth & development ; human reporductive technology; Cryopreservation of organs; Cryopreservation of tissues; political aspects; human reproduction; age factors; feminism
    Language 0|e
    Size 1 electronic resource (344 pages)
    Publisher New York University Press
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021610635
    ISBN 9781479803620 ; 1479803626
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Disrupting the biological clock: Fertility benefits, egg freezing and proactive fertility management.

    van de Wiel, Lucy

    Reproductive biomedicine & society online

    2021  Volume 14, Page(s) 239–250

    Abstract: In the last decade, the in-vitro fertilization (IVF) sector has witnessed a shift from so-called 'reactive IVF' to a new model of proactive fertility care. Whereas IVF was traditionally developed to treat people who found they were unable to conceive, ... ...

    Abstract In the last decade, the in-vitro fertilization (IVF) sector has witnessed a shift from so-called 'reactive IVF' to a new model of proactive fertility care. Whereas IVF was traditionally developed to treat people who found they were unable to conceive, the indication for IVF has broadened significantly to include a much wider group of potential patients through a new focus on proactive treatment of future (in)fertilities. This shift combines a number of new trends pertaining to preservation, prediction, private equity and platformization, all of which have gained influence in contemporary assisted reproduction. This article focuses on the emergence of company-sponsored fertility benefits, which combines each of these trends. Whereas fertility benefits - especially egg freezing insurance - have primarily been discussed in terms of women's empowerment or disenfranchisement, this article instead calls attention to the discursive, clinical and infrastructural shifts in contemporary assisted reproduction that have emerged with the rising popularity of these benefits. The analysis addresses these underdiscussed aspects of fertility benefits by focusing on the dynamics of demand; the shifts in the rationalization of intensified treatment pathways in the face of new reimbursement practices; and the online, platform-based infrastructures that are built to provide these treatments. In doing so, it analyses how this remaking of fertility towards an ethos of proactive fertility management reflects broader capitalist tailwinds.
    Language English
    Publishing date 2021-12-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835432-1
    ISSN 2405-6618 ; 2405-6618
    ISSN (online) 2405-6618
    ISSN 2405-6618
    DOI 10.1016/j.rbms.2021.11.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Disrupting the biological clock

    Lucy van de Wiel

    Reproductive Biomedicine & Society Online, Vol 14, Iss , Pp 239-

    Fertility benefits, egg freezing and proactive fertility management

    2022  Volume 250

    Abstract: In the last decade, the in-vitro fertilization (IVF) sector has witnessed a shift from so-called ‘reactive IVF’ to a new model of proactive fertility care. Whereas IVF was traditionally developed to treat people who found they were unable to conceive, ... ...

    Abstract In the last decade, the in-vitro fertilization (IVF) sector has witnessed a shift from so-called ‘reactive IVF’ to a new model of proactive fertility care. Whereas IVF was traditionally developed to treat people who found they were unable to conceive, the indication for IVF has broadened significantly to include a much wider group of potential patients through a new focus on proactive treatment of future (in)fertilities. This shift combines a number of new trends pertaining to preservation, prediction, private equity and platformization, all of which have gained influence in contemporary assisted reproduction. This article focuses on the emergence of company-sponsored fertility benefits, which combines each of these trends.Whereas fertility benefits – especially egg freezing insurance – have primarily been discussed in terms of women’s empowerment or disenfranchisement, this article instead calls attention to the discursive, clinical and infrastructural shifts in contemporary assisted reproduction that have emerged with the rising popularity of these benefits. The analysis addresses these underdiscussed aspects of fertility benefits by focusing on the dynamics of demand; the shifts in the rationalization of intensified treatment pathways in the face of new reimbursement practices; and the online, platform-based infrastructures that are built to provide these treatments. In doing so, it analyses how this remaking of fertility towards an ethos of proactive fertility management reflects broader capitalist tailwinds.
    Keywords Fertility benefits ; Egg freezing ; IVF ; Insurance ; Fertility ; Add-ons ; Reproduction ; QH471-489 ; Social sciences (General) ; H1-99
    Subject code 331
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: The datafication of reproduction: time-lapse embryo imaging and the commercialisation of IVF.

    van de Wiel, Lucy

    Sociology of health & illness

    2019  Volume 41 Suppl 1, Page(s) 193–209

    Abstract: The 21st century has witnessed the emergence of in silico reproduction alongside the familiar in vitro reproduction (e.g. IVF), as increasingly large and automatically-generated data sets have come to play an instrumental role in assisted reproduction. ... ...

    Abstract The 21st century has witnessed the emergence of in silico reproduction alongside the familiar in vitro reproduction (e.g. IVF), as increasingly large and automatically-generated data sets have come to play an instrumental role in assisted reproduction. The article addresses this datafication of reproduction by analysing time-lapse embryo imaging, a key data-driven technology for embryo selection in IVF cycles. It discusses the new forms of knowledge and value creation enabled by data-driven embryo selection and positions this technology as a harbinger of a wider datafication of (reproductive) health. By analysing the new ways of seeing embryos with 'in silico vision,' the 'data generativity' of developing embryos and the patenting of embryo selection algorithms, I argue that this datafied method of embryo selection may not just result in more or less 'IVF success,' but also affects the conceptualisation and commercialisation of the assisted reproductive process. In doing so, I highlight how the datafication of reproduction both reflects and reinforces a consolidating trend in the fertility sector-characterised by mergers resulting in larger fertility chains, online platforms organising fertility care and expanded portfolios of companies aiming to cover each step of the IVF cycle.
    MeSH term(s) Algorithms ; Embryonic Development/physiology ; Fertilization in Vitro/methods ; Humans ; Medicalization ; Microscopy/methods ; Patents as Topic ; Time-Lapse Imaging/methods
    Language English
    Publishing date 2019-12-22
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 795552-2
    ISSN 1467-9566 ; 0141-9889
    ISSN (online) 1467-9566
    ISSN 0141-9889
    DOI 10.1111/1467-9566.12881
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Passion, pressure and pragmatism: how fertility clinic medical directors view IVF add-ons.

    Iacoponi, Olivia / van de Wiel, Lucy / Wilkinson, Jack / Harper, Joyce C

    Reproductive biomedicine online

    2022  Volume 45, Issue 1, Page(s) 169–179

    Abstract: Research question: What are the views of the medical directors of fertility clinics on IVF add-ons?: Design: A total of 93 UK clinics were emailed with an invitation for their medical director to participate. Ten IVF clinic medical directors were ... ...

    Abstract Research question: What are the views of the medical directors of fertility clinics on IVF add-ons?
    Design: A total of 93 UK clinics were emailed with an invitation for their medical director to participate. Ten IVF clinic medical directors were interviewed to discuss their views on the use of IVF add-ons. Some of the interviewees were medical directors of an IVF clinic with multiple branches across the UK, meaning the total number of clinics accounted for in this study was 35 out of the 93 contacted. Thematic analysis was used to analyse the data.
    Results: The participants consisted of seven males and three females, with six from solely private clinics and four with NHS and private patients. Four themes were identified: clinical decision-making and the patient-doctor relationship; regulations and the add-on traffic light system; research and evidence; and commercialization and financialization of the IVF sector.
    Conclusions: UK IVF medical directors had a wide variety of views and experienced different pressures to offer IVF add-ons. The add-on discussion touches on core aspects of professional identity and the meaning of medical practice. The add-on debate points to broader changes in the organization of the IVF sector, which affect key aspects of practising (reproductive) medicine, including the patient-doctor relationship and responsibility for clinical decision-making, and the relationship between regulator and IVF clinic and between scientific evidence and clinical practice.
    MeSH term(s) Emotions ; Female ; Fertility Clinics ; Fertilization in Vitro ; Humans ; Male ; Physician Executives
    Language English
    Publishing date 2022-03-04
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2113823-0
    ISSN 1472-6491 ; 1472-6483
    ISSN (online) 1472-6491
    ISSN 1472-6483
    DOI 10.1016/j.rbmo.2022.02.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The prevalence, promotion and pricing of three IVF add-ons on fertility clinic websites.

    van de Wiel, Lucy / Wilkinson, Jack / Athanasiou, Pantelitsa / Harper, Joyce

    Reproductive biomedicine online

    2020  Volume 41, Issue 5, Page(s) 801–806

    Abstract: Research question: How are IVF clinic websites advertising three common IVF add-ons: assisted hatching, time-lapse embryo imaging and preimplantation genetic testing for aneuploidies (PGT-A)?: Design: The Human Fertilisation and Embryology Authority ' ...

    Abstract Research question: How are IVF clinic websites advertising three common IVF add-ons: assisted hatching, time-lapse embryo imaging and preimplantation genetic testing for aneuploidies (PGT-A)?
    Design: The Human Fertilisation and Embryology Authority 'Choose a fertility clinic' website service was used to identify IVF clinics and their websites. Assisted hatching, time-lapse embryo imaging and PGT-A were examined to determine which websites advertised them, what price they charged and what claims they made in relation to the add-ons.
    Results: Eighty-seven eligible clinics were identified, with 72 unique websites; 37 (43%) clinics were part of one of nine groups of IVF clinics, of sizes ranging from two to eight clinics in the UK. Time-lapse imaging (TLI) was the most frequently advertised of the three add-ons (67% of clinics), followed by PGT-A (47%) and assisted hatching (28%). Very few websites stated that the effectiveness of the add-on was in doubt or unclear (four, two and one websites for TLI, PGT-A and assisted hatching, respectively), and none raised the possibility that an add-on might have negative effects. Claims of efficacy were often based on upstream outcomes (e.g. implantation, pregnancy). Some claims that PGT-A and TLI improved live birth rates were found. There was substantial variation in pricing.
    Conclusions: IVF clinic websites provide valuable information for patients seeking fertility treatment so it is key that the information is accurate and complete. There is a need for transparent information on interventions, including uncertainties and risks, to be made available by IVF clinics to support well-informed treatment decisions. The selected add-ons are widely advertised, and there is wide variation in pricing.
    MeSH term(s) Commerce ; Female ; Fertility Clinics/economics ; Fertilization in Vitro/economics ; Fertilization in Vitro/methods ; Humans ; Pregnancy ; Preimplantation Diagnosis/economics ; Preimplantation Diagnosis/methods
    Language English
    Publishing date 2020-07-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2113823-0
    ISSN 1472-6491 ; 1472-6483
    ISSN (online) 1472-6491
    ISSN 1472-6483
    DOI 10.1016/j.rbmo.2020.07.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Cycles and circulation: a theme in the history of biology and medicine.

    Hopwood, Nick / Müller-Wille, Staffan / Browne, Janet / Groeben, Christiane / Kuriyama, Shigehisa / van der Lugt, Maaike / Giglioni, Guido / Nyhart, Lynn K / Rheinberger, Hans-Jörg / Dröscher, Ariane / Anderson, Warwick / Anker, Peder / Grote, Mathias / van de Wiel, Lucy

    History and philosophy of the life sciences

    2021  Volume 43, Issue 3, Page(s) 89

    Abstract: We invite systematic consideration of the metaphors of cycles and circulation as a long-term theme in the history of the life and environmental sciences and medicine. Ubiquitous in ancient religious and philosophical traditions, especially in ... ...

    Abstract We invite systematic consideration of the metaphors of cycles and circulation as a long-term theme in the history of the life and environmental sciences and medicine. Ubiquitous in ancient religious and philosophical traditions, especially in representing the seasons and the motions of celestial bodies, circles once symbolized perfection. Over the centuries cyclic images in western medicine, natural philosophy, natural history and eventually biology gained independence from cosmology and theology and came to depend less on strictly circular forms. As potent 'canonical icons', cycles also interacted with representations of linear and irreversible change, including arrows, arcs, scales, series and trees, as in theories of the Earth and of evolution. In modern times life cycles and reproductive cycles have often been held to characterize life, in some cases especially female life, while human efforts selectively to foster and disrupt these cycles have harnessed their productivity in medicine and agriculture. But strong cyclic metaphors have continued to link physiology and climatology, medicine and economics, and biology and manufacturing, notably through the relations between land, food and population. From the grand nineteenth-century transformations of matter to systems ecology, the circulation of molecules through organic and inorganic compartments has posed the problem of maintaining identity in the face of flux and highlights the seductive ability of cyclic schemes to imply closure where no original state was in fact restored. More concerted attention to cycles and circulation will enrich analyses of the power of metaphors to naturalize understandings of life and their shaping by practical interests and political imaginations.
    MeSH term(s) Biology/history ; History of Medicine ; History, 15th Century ; History, 16th Century ; History, 17th Century ; History, 18th Century ; History, 19th Century ; History, 20th Century ; History, 21st Century ; History, Ancient ; History, Medieval ; Philosophy/history
    Language English
    Publishing date 2021-07-12
    Publishing country Switzerland
    Document type Historical Article ; Journal Article
    ZDB-ID 2094240-0
    ISSN 1742-6316 ; 0391-9714
    ISSN (online) 1742-6316
    ISSN 0391-9714
    DOI 10.1007/s40656-021-00425-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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