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  1. Article ; Online: Revolution in echocardiography: From M-mode to printing.

    Lafitte, Stéphane

    Archives of cardiovascular diseases

    2018  Volume 111, Issue 6-7, Page(s) 389–391

    MeSH term(s) Diffusion of Innovation ; Echocardiography, Three-Dimensional/history ; Echocardiography, Three-Dimensional/trends ; Forecasting ; Heart Diseases/diagnostic imaging ; Heart Diseases/history ; Heart Diseases/physiopathology ; Heart Diseases/therapy ; History, 20th Century ; History, 21st Century ; Humans ; Models, Cardiovascular ; Predictive Value of Tests ; Printing, Three-Dimensional/trends ; Prognosis
    Language English
    Publishing date 2018-07-04
    Publishing country Netherlands
    Document type Editorial ; Historical Article
    ZDB-ID 2408778-6
    ISSN 1875-2128 ; 1875-2136
    ISSN (online) 1875-2128
    ISSN 1875-2136
    DOI 10.1016/j.acvd.2018.02.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui IV Zs 8: Show issues Location:
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  2. Article ; Online: Pinpointing gravitational waves via astrometric gravitational wave antennas.

    Crosta, Mariateresa / Lattanzi, Mario Gilberto / Le Poncin-Lafitte, Christophe / Gai, Mario / Zhaoxiang, Qi / Vecchiato, Alberto

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 5074

    Abstract: The direct detection of gravitational waves by ground-based optical interferometers has opened a new window in astronomy. Besides, the sensitivity of these linear detectors to the direction of arrival of an incoming gravitational wave is limited compared ...

    Abstract The direct detection of gravitational waves by ground-based optical interferometers has opened a new window in astronomy. Besides, the sensitivity of these linear detectors to the direction of arrival of an incoming gravitational wave is limited compared to current prospects of high-precision, space-based, astrometry. Indeed, advanced methods of differential relativistic astrometry offer a unique opportunity to overcome that situation. Here, we present a novel concept for a gravitational wave antenna that uses angles between close pairs of point-like sources as natural (angular) "arms" to characterise the very tiny variations in angular separations induced by a passing gravitational wave. The proposed new astrometric gravitational wave observable proves to be a powerful tool to substantially enhance the effect of gravitational waves of different strengths by exploiting optical resolution to the fullest. Then, by optically multiplexing three (or more) of such astrometric "arms", it would be also possible to pinpoint source directions to unprecedented levels.
    Language English
    Publishing date 2024-03-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-55671-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Percutaneous irreversible electroporation for the treatment of pancreatic insulinoma.

    Tasu, Jean-Pierre / Vionnet, Mathilde / Velasco, Stéphane / Lafitte, Luc / Poignard, Clair

    Diagnostic and interventional imaging

    2023  Volume 104, Issue 6, Page(s) 307–308

    MeSH term(s) Humans ; Insulinoma/diagnostic imaging ; Insulinoma/surgery ; Pancreatic Neoplasms/diagnostic imaging ; Pancreatic Neoplasms/therapy ; Pancreas ; Electroporation ; Treatment Outcome
    Language English
    Publishing date 2023-03-28
    Publishing country France
    Document type Letter
    ZDB-ID 2648283-6
    ISSN 2211-5684 ; 2211-5684
    ISSN (online) 2211-5684
    ISSN 2211-5684
    DOI 10.1016/j.diii.2023.03.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Occurrence and distribution of PAHs in stranded dolphin tissues from the Northwestern Mediterranean.

    Dron, Julien / Wafo, Emmanuel / Boissery, Pierre / Dhermain, Frank / Bouchoucha, Marc / Chamaret, Philippe / Lafitte, Daniel

    Marine pollution bulletin

    2023  Volume 191, Page(s) 114898

    Abstract: There are few cetacean tissue-specific polycyclic aromatic hydrocarbon (PAH) concentration studies in the Mediterranean, despite this region is among the most subjected to chemical contamination. PAH analyses were conducted in different tissues of ... ...

    Abstract There are few cetacean tissue-specific polycyclic aromatic hydrocarbon (PAH) concentration studies in the Mediterranean, despite this region is among the most subjected to chemical contamination. PAH analyses were conducted in different tissues of striped dolphins (Stenella coeruleoalba, N = 64) and bottlenose dolphins (Tursiops truncatus, N = 9) stranded along the French Mediterranean coastline from 2010 to 2016. Comparable levels were measured in S. coeruleoalba and T. trucantus (1020 and 981 ng g
    MeSH term(s) Animals ; Male ; Stenella ; Bottle-Nosed Dolphin ; Cetacea ; Mediterranean Sea
    Language English
    Publishing date 2023-04-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2001296-2
    ISSN 1879-3363 ; 0025-326X
    ISSN (online) 1879-3363
    ISSN 0025-326X
    DOI 10.1016/j.marpolbul.2023.114898
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  5. Article: Collagen Kinase Receptors as Potential Therapeutic Targets in Metastatic Colon Cancer.

    Lafitte, Marie / Sirvent, Audrey / Roche, Serge

    Frontiers in oncology

    2020  Volume 10, Page(s) 125

    Abstract: Colorectal cancer (CRC) is one of the leading causes of tumor-related death worldwide. While surgery can cure patients with early stage CRC, the 5-year survival rate is only 10% for patients with metastatic disease. Therefore, new anti-metastatic ... ...

    Abstract Colorectal cancer (CRC) is one of the leading causes of tumor-related death worldwide. While surgery can cure patients with early stage CRC, the 5-year survival rate is only 10% for patients with metastatic disease. Therefore, new anti-metastatic therapies are needed for this cancer. Metastatic spread defines the dissemination of cancer cells with tumor-initiating capacities from the primary tumor and their colonization of distinct organs, mainly the liver, for secondary tumor formation. Although the underlying mechanisms are not fully understood, components of the tumor microenvironment have gained strong interest. Among the known metastatic-promoting factors, collagens are extracellular matrix components that are deposited within the tumor, the tumor microenvironment, and at metastatic site(s), and are recognized to play essential roles during metastasis development. Here, we review recent findings on the metastatic role of the collagen receptors Discoidin Domain Receptors 1 and 2 (DDR1 and DDR2) in CRC and discuss the therapeutic value of targeting these receptor tyrosine kinases in this cancer.
    Language English
    Publishing date 2020-02-12
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2020.00125
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Valve-in-Valve After Transcatheter Mitral Valve Replacement: Anticipate the Future!

    Leroux, Lionel / Ternacle, Julien / Bonnet, Guillaume / Dijos, Marina / Jonveaux, Melchior / Pernot, Mathieu / Lafitte, Stéphane / Labrousse, Louis / Modine, Thomas

    JACC. Cardiovascular interventions

    2023  Volume 16, Issue 12, Page(s) 1531–1536

    MeSH term(s) Humans ; Mitral Valve/diagnostic imaging ; Mitral Valve/surgery ; Treatment Outcome ; Catheters
    Language English
    Publishing date 2023-05-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2452157-7
    ISSN 1876-7605 ; 1936-8798
    ISSN (online) 1876-7605
    ISSN 1936-8798
    DOI 10.1016/j.jcin.2023.03.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6669: Show issues Location:
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  7. Article ; Online: Long-term outcomes of concomitant suture bicuspidization technique to treat mild or moderate tricuspid regurgitation in patients undergoing mitral valve surgery.

    Piperata, Antonio / Van Den Eynde, Jef / Pernot, Mathieu / Busuttil, Olivier / Avesani, Martina / Bottio, Tomaso / Lafitte, Stephane / Modine, Thomas / Labrousse, Louis

    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

    2023  Volume 63, Issue 6

    Abstract: Objectives: The aim of this study was to investigate the long-term outcomes of concomitant suture bicuspidization to treat mild or moderate tricuspid regurgitation at the time of mitral valve (MV) surgery.: Methods: Data from patients who underwent ... ...

    Abstract Objectives: The aim of this study was to investigate the long-term outcomes of concomitant suture bicuspidization to treat mild or moderate tricuspid regurgitation at the time of mitral valve (MV) surgery.
    Methods: Data from patients who underwent MV surgery for degenerative MV regurgitation with mild or moderate tricuspid regurgitation and annular dilatation between January 2009 and December 2017 were analysed. The cohort was divided into 2 groups: mitral valve surgery alone (MVA) and MV surgery with concomitant tricuspid valve (TV) repair.
    Results: A total of 196 patients were included in the study. MVA and MV surgery with concomitant TV repair were performed in 91 (46.4%) and 105 (53.6%) patients, respectively. Propensity score matching analysis identified 54 pairs. In the matched cohort, 30-day mortality (0.0% vs 1.9%, P = 1.0) and new permanent pacemaker implantation (11.1% vs 7.4%, P = 0.740) did not differ significantly between groups. After a mean follow-up of 6.0 (2.8) years, MV surgery with concomitant TV repair was not associated with increased mortality risk compared to MVA (hazard ratio 1.04, 95% confidence interval 0.47-2.28, P = 0.927) with 10-year overall survival rates of 69.9% and 77.2%, respectively. Furthermore, MV surgery with concomitant TV repair was associated with a significantly reduced progression of TV regurgitation (P < 0.001).
    Conclusions: Patients undergoing MV surgery with concomitant TV repair had similar 30-day and long-term survival, similar permanent pacemaker implantation rate and reduced progression of TV regurgitation compared to those undergoing MVA.
    MeSH term(s) Humans ; Tricuspid Valve Insufficiency/complications ; Mitral Valve/surgery ; Heart Valve Prosthesis Implantation/methods ; Treatment Outcome ; Mitral Valve Insufficiency ; Sutures ; Retrospective Studies
    Language English
    Publishing date 2023-06-19
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 639293-3
    ISSN 1873-734X ; 1010-7940 ; 1567-4258
    ISSN (online) 1873-734X
    ISSN 1010-7940 ; 1567-4258
    DOI 10.1093/ejcts/ezad201
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2303: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  8. Article: Venous dysfunction in obstructive hypertrophic cardiomyopathies: Results from the "HCM-Vein" pilot study.

    Réant, Patricia / Bonnet, Guillaume / Massie, Charles / Dezellus, Alexandre / Reynaud, Amélie / Michaud, Matthieu / James, Chloé / Constans, Joël / Lafitte, Stéphane

    International journal of cardiology. Heart & vasculature

    2023  Volume 45, Page(s) 101198

    Abstract: Background: Hypertrophic cardiomyopathies (HCM) can be complicated by left ventricular outflow-tract obstruction (LVOTO) responsible for disabling exercise symptoms, a phenomenon influenced by hemodynamic factors including venous return.: Methods: We ...

    Abstract Background: Hypertrophic cardiomyopathies (HCM) can be complicated by left ventricular outflow-tract obstruction (LVOTO) responsible for disabling exercise symptoms, a phenomenon influenced by hemodynamic factors including venous return.
    Methods: We aimed to evaluate venous dysfunction in obstructive HCM patients compared to healthy controls, and to investigate the relationship between venous dysfunction parameters and LVOTO in HCM. This is a clinical, monocentric, prospective, pilot study, in a tertiary care center. We investigated venous function using venous air plethysmography, and endothelial function.
    Results: Among the 30 symptomatic obstructive HCM patients, 30% (n = 9) presented abnormal venous residual volume fraction (RVFv) which translates in elevated ambulatory venous pressure
    Conclusions: In this pilot monocentric study, venous insufficiency was observed in about 30% of symptomatic obstructive HCM patients. Patients with venous insufficiency had more frequently a smaller LV cavity volume. Due to the small sample size, this study is only hypothesis-generating, and further investigations are needed.
    Language English
    Publishing date 2023-03-21
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 2818464-6
    ISSN 2352-9067
    ISSN 2352-9067
    DOI 10.1016/j.ijcha.2023.101198
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  9. Article ; Online: Colloidal Self-Assembly of Silver Nanoparticle Clusters for Optical Metasurfaces.

    Lafitte, Maeva / Dwivedi, Ranjeet / Elancheliyan, Rajam / Lagugné-Labarthet, François / Buisson, Lionel / Ly, Isabelle / Barois, Philippe / Baron, Alexandre / Mondain-Monval, Olivier / Ponsinet, Virginie

    Langmuir : the ACS journal of surfaces and colloids

    2024  Volume 40, Issue 5, Page(s) 2601–2615

    Abstract: Optical metasurfaces are two-dimensional assemblies of nanoscale optical resonators and could constitute the next generation of ultrathin optical components. The development of methods to manufacture these nanostructures on a large scale is still a ... ...

    Abstract Optical metasurfaces are two-dimensional assemblies of nanoscale optical resonators and could constitute the next generation of ultrathin optical components. The development of methods to manufacture these nanostructures on a large scale is still a challenge, while most performance demonstrations were obtained with lithographically fabricated metasurfaces that are restricted to small scales. Self-assembly fabrication routes are promising alternatives and have been used to produce original nanoresonators. Reports of self-assembled metasurface fabrication, however, are still scarce. Here, we show that an emulsion-based formulation approach can be used both for the fabrication of complex colloidal resonators, presenting a strong interaction with light, in particular due to simultaneous magnetic and electric modes of resonance, and for their deposition in homogeneous films. This fabrication technique involves emulsification of an aqueous suspension of silver nanoparticles in an oil phase, followed by controlled drying of the emulsion, and produces silver colloidal clusters. We show that the drying process can be controlled in a liquid emulsion, producing a metafluid, as well as in a sedimented emulsion, producing a metasurface. The structural control of the synthesized colloidal clusters is demonstrated with electron microscopy and X-ray scattering techniques. Using a polarization-resolved multiangle light scattering setup in the visible wavelength range, we conduct a comprehensive angular and spectroscopic study of the optical resonant scattering of the nanoresonators in a metafluid and show that they present strong optical magnetic resonances and directional forward-scattering patterns, with scattering efficiencies of up to 4. The metasurfaces consist of homogeneous films, of variable surface density, of colloidal clusters that have the same extinction properties on the surface and in the fluid. This experimental approach allows for large-scale production of metasurfaces.
    Language English
    Publishing date 2024-01-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.3c02900
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Roles of exosomes in metastatic colorectal cancer.

    Lafitte, Marie / Lecointre, Céline / Roche, Serge

    American journal of physiology. Cell physiology

    2019  Volume 317, Issue 5, Page(s) C869–C880

    Abstract: Metastases remain a major cause of cancer morbidity and mortality. This is a multistep process that involves aberrant cell communication, leading to tumor cell dissemination from the primary tumor and colonization of distinct organs for secondary tumor ... ...

    Abstract Metastases remain a major cause of cancer morbidity and mortality. This is a multistep process that involves aberrant cell communication, leading to tumor cell dissemination from the primary tumor and colonization of distinct organs for secondary tumor formation. The mechanisms promoting this pathological process are not fully understood, although they may be of obvious therapeutic interest. Exosomes are small cell-secreted vesicles that contain a large variety of proteins, lipids, and nucleic acids with important signaling activities, and that represent an evolutionarily conserved mechanism for cell-to-cell communication. Not surprisingly, exosome activities have gained strong interest in cancer biology and might play essential roles in metastasis development. Here, we will describe recent findings on the role of exosomes in cancer metastasis formation, particularly in colorectal cancer (CRC). We will also discuss the potential therapeutic value of these vesicles in metastatic cancer.
    MeSH term(s) Animals ; Biomarkers, Tumor/metabolism ; Cancer Vaccines/administration & dosage ; Cancer Vaccines/metabolism ; Colorectal Neoplasms/drug therapy ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/pathology ; Exosomes/metabolism ; Exosomes/pathology ; Humans ; Neoplasm Invasiveness/pathology ; Neoplasm Invasiveness/prevention & control ; Tumor Microenvironment/physiology
    Chemical Substances Biomarkers, Tumor ; Cancer Vaccines
    Language English
    Publishing date 2019-07-10
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 392098-7
    ISSN 1522-1563 ; 0363-6143
    ISSN (online) 1522-1563
    ISSN 0363-6143
    DOI 10.1152/ajpcell.00218.2019
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    Uc I Zs.89: Show issues Location:
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