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  1. Article ; Online: COVID-19 and the unseen pandemic of child abuse.

    Park, Wesley J / Walsh, Kristen A

    BMJ paediatrics open

    2022  Volume 6, Issue 1

    MeSH term(s) Child ; Humans ; COVID-19/epidemiology ; Pandemics ; Child Abuse/prevention & control
    Language English
    Publishing date 2022-09-30
    Publishing country England
    Document type Journal Article
    ISSN 2399-9772
    ISSN (online) 2399-9772
    DOI 10.1136/bmjpo-2022-001553
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  2. Article: Periocular irritation in elderly Asian patient.

    Park, Kristen E / Saber, Maria Sibug / Rao, Narsing A / Zhang-Nunes, Sandy

    JAAD case reports

    2023  Volume 35, Page(s) 19–21

    Language English
    Publishing date 2023-03-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2834220-3
    ISSN 2352-5126
    ISSN 2352-5126
    DOI 10.1016/j.jdcr.2023.02.013
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  3. Article: Updated Review Article: Cyclin-Dependent Kinase 4/6 Inhibitor Impact, FDA Approval, and Resistance Pathways.

    Hunter, Rodney J / Park, Jooyoung / Asprer, Kristen J / Doan, Andrew H

    The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians

    2023  Volume 39, Issue 6, Page(s) 298–308

    Abstract: Objective: ...

    Abstract Objective:
    Language English
    Publishing date 2023-10-24
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 54478-4
    ISSN 8755-1225
    ISSN 8755-1225
    DOI 10.1177/87551225231205153
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3673: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
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  4. Article ; Online: Alleviating Financial Hardships Associated with High-Deductible Health Plans for Adults with Chronic Conditions Through Health Savings Accounts.

    Park, Kristen E / Saluja, Sonali / Kaplan, Cameron M

    Journal of general internal medicine

    2023  Volume 38, Issue 7, Page(s) 1593–1598

    Abstract: Background: High-deductible health plans (HDHPs) are becoming increasingly common, but their financial implications for enrollees with and without chronic conditions and the mitigating effects of health savings accounts (HSAs) are relatively unknown.: ...

    Abstract Background: High-deductible health plans (HDHPs) are becoming increasingly common, but their financial implications for enrollees with and without chronic conditions and the mitigating effects of health savings accounts (HSAs) are relatively unknown.
    Objective: Our aim was to compare financial hardship between non-HDHPs and HDHPs with and without HSAs, stratified by enrollees' number of chronic conditions.
    Design: We used data from 2015 to 2018 Medical Expenditure Panels Surveys (MEPS) to compare rates of financial hardship across individuals with HDHPs and non-HDHPs using linear and logistic regression models.
    Participants: A nationally representative sample of 30,981 adults aged 18-64 enrolled in HDHPs and non-HDHPs.
    Main measures: We examined several measures of financial hardship, including total yearly out-of-pocket medical spending as well as rates of delaying medical care or prescriptions in the past year due to cost, forgoing medical care or prescriptions in the past year due to cost, paying medical bills over time, or having problems paying medical bills. We compared rates using the non-HDHP as the control.
    Key results: On most measures, HDHPs are associated with greater financial hardship compared to non-HDHPs, including average annual out-of-pocket spending of $637 for non-HDHPs, $939 for HDHPs with HSAs, and $825 for HDHPs without HSAs (p < 0.01). However, for HDHP enrollees with multiple chronic conditions, having an HSA was associated with less financial hardship (p < 0.05).
    Conclusions: Our findings suggest that HSAs may be most beneficial for those with chronic conditions, in part due to the tax benefits they offer as well as the fact that those with chronic conditions are more likely to take advantage of their HSAs than their younger, healthier counterparts. However, as HDHPs are more likely to be correlated with worse financial outcomes regardless of health status, recent trends of increasing participation may be a reason for concern.
    MeSH term(s) Adult ; Humans ; United States/epidemiology ; Medical Savings Accounts ; Deductibles and Coinsurance ; Financial Stress ; Health Expenditures ; Chronic Disease
    Language English
    Publishing date 2023-01-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639008-0
    ISSN 1525-1497 ; 0884-8734
    ISSN (online) 1525-1497
    ISSN 0884-8734
    DOI 10.1007/s11606-022-07985-5
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2205: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  5. Article ; Online: Introduction. Surgery for sacroiliac joint dysfunction: emerging techniques and assistive technologies.

    Park, Paul / Jones, Kristen E / Saadeh, Yamaan S / Menezes, Cristiano M / Uribe, Juan S

    Neurosurgical focus

    2023  Volume 55, Issue 1, Page(s) E1

    MeSH term(s) Humans ; Sacroiliac Joint/surgery ; Self-Help Devices
    Language English
    Publishing date 2023-07-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2026589-X
    ISSN 1092-0684 ; 1092-0684
    ISSN (online) 1092-0684
    ISSN 1092-0684
    DOI 10.3171/2023.4.FOCUS23250
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  6. Article ; Online: Atrial fibrillation induced by gabapentin: a case report.

    Park, Sung Hwan / Hunter, Kristen / Berry, Hugh / Martins, Yuri Chaves

    Journal of medical case reports

    2023  Volume 17, Issue 1, Page(s) 236

    Abstract: Background: Gabapentin is commonly prescribed for the treatment of neuropathic pain, restless leg syndrome, and partial-onset seizures. Although the most frequent side effects of gabapentin are associated with the central nervous system, gabapentin can ... ...

    Abstract Background: Gabapentin is commonly prescribed for the treatment of neuropathic pain, restless leg syndrome, and partial-onset seizures. Although the most frequent side effects of gabapentin are associated with the central nervous system, gabapentin can also affect the cardiovascular system. Case reports and observational studies have showed that gabapentin can be associated with increased risk of atrial fibrillation. However, all the evidence is concentrated in patients older than 65 years old with comorbidities that predispose them to the development of arrhythmias.
    Case presentation: We describe a case of an African American male in his 20s that presented to our chronic pain clinic with lumbar radiculitis and developed atrial fibrillation 4 days after being started on gabapentin. Laboratory workup did not show significant abnormalities, including normal complete blood count, comprehensive metabolic panel, toxicology screen, and thyroid-stimulating hormone. Transthoracic and transesophageal echocardiography showed a patent foramen ovale with right-to-left shunt. The patient was initially treated with diltiazem for heart rate control and apixaban. Direct current cardioversion with successful conversion to sinus rhythm was performed 24 hours after admission. The patient was then discharged on apixaban and diltiazem. Apixaban was changed to low-dose aspirin 1 month after discharge.
    Conclusion: With rapidly increasing usage of gabapentin for approved and off-label indications, it is important to identify unintended adverse effects of this drug as they are considered safe alternatives to opioids. New-onset atrial fibrillation could be induced by gabapentin in young individuals.
    MeSH term(s) Humans ; Male ; Aged ; Atrial Fibrillation/drug therapy ; Atrial Fibrillation/complications ; Gabapentin/adverse effects ; Diltiazem/therapeutic use ; Echocardiography, Transesophageal ; Electric Countershock
    Chemical Substances Gabapentin (6CW7F3G59X) ; Diltiazem (EE92BBP03H)
    Language English
    Publishing date 2023-06-09
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2269805-X
    ISSN 1752-1947 ; 1752-1947
    ISSN (online) 1752-1947
    ISSN 1752-1947
    DOI 10.1186/s13256-023-03975-1
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  7. Article ; Online: Sense of community and mental health: a cross-sectional analysis from a household survey in Wisconsin.

    Park, Eunice Y / Oliver, Thomas R / Peppard, Paul E / Malecki, Kristen C

    Family medicine and community health

    2023  Volume 11, Issue 2

    Abstract: Background: In the USA, one in five adults live with a mental illness, and researchers have estimated that nearly half of the population will have a mental illness over the course of their lifetime. Research has shown significant associations between ... ...

    Abstract Background: In the USA, one in five adults live with a mental illness, and researchers have estimated that nearly half of the population will have a mental illness over the course of their lifetime. Research has shown significant associations between social relationships and mental health outcomes at the individual and population levels. This study aims to examine whether sense of community, a type of social capital, is associated with mental health.
    Methods: In a cross-sectional analysis, multiple logistic regression models were used to examine whether sense of community was associated with symptoms of depression, anxiety and stress reported over the last week. The analysis used data from the Survey of the Health of Wisconsin collected between 2014 and 2016. A total of 1647 observations are included in the analyses.
    Results: Compared with those who report a positive sense of community, those with a negative sense of community had a significantly higher odds of reporting depression, anxiety and stress symptoms. Socioeconomic status is negatively associated with depression and anxiety, but not with stress. Women were more likely to experience moderate, severe, or extremely severe anxiety and stress, compared with men.
    Conclusion: This study extends current understanding of health benefits of social capital and found that individuals' sense of community is associated with reduced symptoms of depression, anxiety and stress. Further research examining mechanisms to support improved sense of community and other types of social capital could benefit health equity research.
    MeSH term(s) Adult ; Male ; Humans ; Female ; Mental Health ; Cross-Sectional Studies ; Depression/epidemiology ; Wisconsin ; Social Cohesion
    Language English
    Publishing date 2023-07-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2986753-8
    ISSN 2009-8774 ; 2305-6983
    ISSN (online) 2009-8774
    ISSN 2305-6983
    DOI 10.1136/fmch-2022-001971
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  8. Article ; Online: Safety of medications for hereditary angioedema during pregnancy and lactation.

    Yeich, Andrew / Elhatw, Ahmed / Ashoor, Zaynab / Park, Kristen / Craig, Timothy

    Expert opinion on drug safety

    2023  Volume 22, Issue 1, Page(s) 17–24

    Abstract: Introduction: Hereditary Angioedema (HAE) attacks show an increased frequency and severity for pregnant and lactating females secondary to the hormonal changes. The diagnosis and management of HAE in pregnant and lactating females pose a challenge for ... ...

    Abstract Introduction: Hereditary Angioedema (HAE) attacks show an increased frequency and severity for pregnant and lactating females secondary to the hormonal changes. The diagnosis and management of HAE in pregnant and lactating females pose a challenge for physicians due to the rarity of the disease and the paucity of the data for specific management.
    Areas covered: In this manuscript, we discuss the diagnosis and special presentation of HAE types 1 and 2 in pregnant and lactating females, including acute management, short-term prophylaxis, long-term prophylaxis, and drugs that should be avoided. Relevant publications were found through key word search of papers indexed in both Google Scholar and PubMed on 1 July 2022.
    Expert opinion: Treatment of HAE in the past has been mainly provided by experts; however, with more medications and an increasing number of patients, knowledge of how to care for HAE patients during pregnancy and lactation is important to review. Despite approval of additional medications in many countries, plasma-derived C1-inhibitor remains the drug of first choice for treatment in this unique population. Additional research is needed to increase safe access to other therapy options. We hope that future clinical studies, registries, and databases will shed additional light on this subject.
    MeSH term(s) Pregnancy ; Female ; Humans ; Angioedemas, Hereditary/diagnosis ; Angioedemas, Hereditary/drug therapy ; Lactation ; Complement C1 Inhibitor Protein/therapeutic use ; Breast Feeding ; Excipients
    Chemical Substances Complement C1 Inhibitor Protein ; Excipients
    Language English
    Publishing date 2023-02-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2088728-0
    ISSN 1744-764X ; 1474-0338
    ISSN (online) 1744-764X
    ISSN 1474-0338
    DOI 10.1080/14740338.2023.2177269
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6096: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Atrial fibrillation induced by gabapentin

    Sung Hwan Park / Kristen Hunter / Hugh Berry / Yuri Chaves Martins

    Journal of Medical Case Reports, Vol 17, Iss 1, Pp 1-

    a case report

    2023  Volume 5

    Abstract: Abstract Background Gabapentin is commonly prescribed for the treatment of neuropathic pain, restless leg syndrome, and partial-onset seizures. Although the most frequent side effects of gabapentin are associated with the central nervous system, ... ...

    Abstract Abstract Background Gabapentin is commonly prescribed for the treatment of neuropathic pain, restless leg syndrome, and partial-onset seizures. Although the most frequent side effects of gabapentin are associated with the central nervous system, gabapentin can also affect the cardiovascular system. Case reports and observational studies have showed that gabapentin can be associated with increased risk of atrial fibrillation. However, all the evidence is concentrated in patients older than 65 years old with comorbidities that predispose them to the development of arrhythmias. Case presentation We describe a case of an African American male in his 20s that presented to our chronic pain clinic with lumbar radiculitis and developed atrial fibrillation 4 days after being started on gabapentin. Laboratory workup did not show significant abnormalities, including normal complete blood count, comprehensive metabolic panel, toxicology screen, and thyroid-stimulating hormone. Transthoracic and transesophageal echocardiography showed a patent foramen ovale with right-to-left shunt. The patient was initially treated with diltiazem for heart rate control and apixaban. Direct current cardioversion with successful conversion to sinus rhythm was performed 24 hours after admission. The patient was then discharged on apixaban and diltiazem. Apixaban was changed to low-dose aspirin 1 month after discharge. Conclusion With rapidly increasing usage of gabapentin for approved and off-label indications, it is important to identify unintended adverse effects of this drug as they are considered safe alternatives to opioids. New-onset atrial fibrillation could be induced by gabapentin in young individuals.
    Keywords Gabapentin ; Atrial fibrillation ; Adverse side effects ; Case report ; Medicine ; R
    Subject code 616
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: TDP-43 impairs sleep in

    Perlegos, Alexandra E / Durkin, Jaclyn / Belfer, Samuel J / Rodriguez, Anyara / Shcherbakova, Oksana / Park, Kristen / Luong, Jenny / Bonini, Nancy M / Kayser, Matthew S

    Science advances

    2024  Volume 10, Issue 2, Page(s) eadj4457

    Abstract: Neurodegenerative diseases such as amyotrophic lateral sclerosis and frontotemporal dementia are associated with substantial sleep disruption, which may accelerate cognitive decline and brain degeneration. Here, we define a role for trans-activation ... ...

    Abstract Neurodegenerative diseases such as amyotrophic lateral sclerosis and frontotemporal dementia are associated with substantial sleep disruption, which may accelerate cognitive decline and brain degeneration. Here, we define a role for trans-activation response element (TAR) DNA binding protein 43 (TDP-43), a protein associated with human neurodegenerative disease, in regulating sleep using
    MeSH term(s) Animals ; Humans ; Amyotrophic Lateral Sclerosis ; Ataxin-2 ; DNA-Binding Proteins/genetics ; Drosophila ; Neurodegenerative Diseases
    Chemical Substances Ataxin-2 ; DNA-Binding Proteins ; ATX2 protein, Drosophila ; TBPH protein, Drosophila
    Language English
    Publishing date 2024-01-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2810933-8
    ISSN 2375-2548 ; 2375-2548
    ISSN (online) 2375-2548
    ISSN 2375-2548
    DOI 10.1126/sciadv.adj4457
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