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  1. Article ; Online: Uvular Necrosis: A Rare Complication After Esophagogastroduodenoscopy.

    Mohamed, Mouhand F H / Shah, Samir A

    The American journal of gastroenterology

    2023  Volume 118, Issue 10, Page(s) 1732

    MeSH term(s) Humans ; Necrosis/etiology ; Endoscopy, Digestive System/adverse effects ; Uvula
    Language English
    Publishing date 2023-06-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 390122-1
    ISSN 1572-0241 ; 0002-9270
    ISSN (online) 1572-0241
    ISSN 0002-9270
    DOI 10.14309/ajg.0000000000002377
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The Utility of Ultrasound Extends Beyond Interstitial Pneumonia Assessment in COVID-19 Patients.

    Mohamed, Mouhand F H

    Academic radiology

    2020  Volume 27, Issue 9, Page(s) 1332–1333

    Keywords covid19
    Language English
    Publishing date 2020-07-07
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1355509-1
    ISSN 1878-4046 ; 1076-6332
    ISSN (online) 1878-4046
    ISSN 1076-6332
    DOI 10.1016/j.acra.2020.06.025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Caution Is Needed When Reporting or Pooling the Prevalence of Venous Thromboembolism in Critically Ill Coronavirus Disease 2019 Patients.

    Mohamed, Mouhand F H

    Critical care medicine

    2020  Volume 49, Issue 1, Page(s) e114–e115

    MeSH term(s) Anticoagulants ; COVID-19 ; Critical Illness ; Humans ; Incidence ; Prevalence ; SARS-CoV-2 ; Venous Thromboembolism
    Chemical Substances Anticoagulants
    Keywords covid19
    Language English
    Publishing date 2020-11-05
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000004693
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Cold snare endoscopic mucosal resection for colonic polyps: addressing methodological critiques and enhancing future discussions.

    Mohamed, Mouhand F H / Abdallah, Mohamed / Ahmed, Khalid / Jaber, Fouad / Bilal, Mohammad

    Endoscopy

    2023  Volume 56, Issue 1, Page(s) 79–80

    MeSH term(s) Humans ; Colonic Polyps/surgery ; Colonoscopy ; Endoscopic Mucosal Resection ; Colorectal Neoplasms/surgery ; Microsurgery
    Language English
    Publishing date 2023-12-21
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/a-2162-7890
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Efficacy, Safety, and Cost-effectiveness of Bezlotoxumab in Preventing Recurrent Clostridioides difficile Infection : Systematic Review and Meta-analysis.

    Mohamed, Mouhand F H / Ward, Christopher / Beran, Azizullah / Abdallah, Mohamed A / Asemota, Joseph / Kelly, Colleen R

    Journal of clinical gastroenterology

    2024  Volume 58, Issue 4, Page(s) 389–401

    Abstract: Introduction: Clostridioides difficile infection (CDI) remains a global health challenge. Bezlotoxumab (BEZ) is a monoclonal antibody against C. difficile toxin B. Two randomized controlled trials (RCTs), MODIFY I and II, confirmed BEZ efficacy in ... ...

    Abstract Introduction: Clostridioides difficile infection (CDI) remains a global health challenge. Bezlotoxumab (BEZ) is a monoclonal antibody against C. difficile toxin B. Two randomized controlled trials (RCTs), MODIFY I and II, confirmed BEZ efficacy in preventing recurrent Clostridioides difficile infection (rCDI). However, there are safety concerns about its use in patients with a history of congestive heart failure. Observational studies have since been conducted, and it is important to explore the consistency of BEZ efficacy, cost-effectiveness, and its safety utilizing these real-world data.
    Methods: We performed a systematic review and meta-analysis to pool the rate of rCDI in patients receiving BEZ and explore its efficacy and safety in preventing rCDI compared with control. We searched PubMed, EMBASE, Cochrane Library, and Google Scholar from inception through April 2023 for relevant RCTs or observational studies assessing BEZ in preventing rCDI. Single-arm studies describing experience with BEZ in preventing rCDI were also included for proportion meta-analysis. A proportion meta-analysis with a random-effects model was used to pool the rCDI rate with its corresponding 95% CI. In a meta-analysis of efficacy, we generated the relative risk (RR) to compare BEZ versus control in preventing rCDI.
    Results: Thirteen studies including 2 RCTs and 11 observational studies totaling 2337 patients, of which 1472 received BEZ, were included in the analysis. Of the constituent studies, 5 (1734 patients) compared BEZ versus standard-of-care (SOC). Pooled rate of rCDI in patients receiving BEZ was 15.8% (95% CI: 14%-17.8%), and was 28.9% (95% CI: 24%-34.4%) in the SOC. BEZ significantly reduced rCDI risk compared with SOC [RR=0.57 (95% CI: 0.45-0.72, I2 =16%)]. There was no difference in the overall mortality or heart failure risk. Of the 9 included cost-effectiveness analyses, 8 demonstrated BEZ+SOC cost-effectiveness compared with SOC alone.
    Discussion: Our meta-analysis comprising real-world data revealed lower rCDI in patients receiving BEZ and supported its efficacy and safety when added to SOC therapy. The results were consistent across various subgroups. Available cost-effectiveness analyses mostly support BEZ+SOC cost-effectiveness compared with SOC alone.
    MeSH term(s) Humans ; Anti-Bacterial Agents/adverse effects ; Cost-Benefit Analysis ; Clostridioides difficile ; Recurrence ; Clostridium Infections ; Antibodies, Monoclonal/adverse effects ; Broadly Neutralizing Antibodies
    Chemical Substances bezlotoxumab (4H5YMK1H2E) ; Anti-Bacterial Agents ; Antibodies, Monoclonal ; Broadly Neutralizing Antibodies
    Language English
    Publishing date 2024-04-01
    Publishing country United States
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 448460-5
    ISSN 1539-2031 ; 0192-0790
    ISSN (online) 1539-2031
    ISSN 0192-0790
    DOI 10.1097/MCG.0000000000001875
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Acute abdomen is not always surgical amid the COVID-19 pandemic.

    Ahmed, Khalid / Mohamed, Mouhand F H

    The British journal of surgery

    2020  Volume 107, Issue 10, Page(s) e434–e435

    MeSH term(s) Abdomen, Acute/etiology ; COVID-19/complications ; COVID-19/epidemiology ; Digestive System Diseases/complications ; Digestive System Diseases/virology ; Humans ; Pandemics ; SARS-CoV-2 ; Thrombosis/complications ; Thrombosis/virology
    Keywords covid19
    Language English
    Publishing date 2020-08-05
    Publishing country England
    Document type Letter
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1002/bjs.11883
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The Utility of Ultrasound Extends Beyond Interstitial Pneumonia Assessment in COVID-19 Patients

    Mohamed, Mouhand F.H.

    Academic Radiology

    2020  Volume 27, Issue 9, Page(s) 1332–1333

    Keywords Radiology Nuclear Medicine and imaging ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 1355509-1
    ISSN 1076-6332
    ISSN 1076-6332
    DOI 10.1016/j.acra.2020.06.025
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Severe COVID-19 Pneumonia Complicated by Pneumothorax, Pneumomediastinum, and Pneumoperitoneum.

    Ahmed, Ashraf O E / Mohamed, Mouhand F H / Ahmed, Khalid

    The American journal of tropical medicine and hygiene

    2021  Volume 104, Issue 6, Page(s) 1951–1952

    MeSH term(s) COVID-19/complications ; COVID-19/pathology ; COVID-19/therapy ; Humans ; Male ; Mediastinal Emphysema/etiology ; Middle Aged ; Pneumoperitoneum/etiology ; Pneumothorax/etiology ; SARS-CoV-2
    Language English
    Publishing date 2021-04-05
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2942-7
    ISSN 1476-1645 ; 0002-9637
    ISSN (online) 1476-1645
    ISSN 0002-9637
    DOI 10.4269/ajtmh.21-0092
    Database MEDical Literature Analysis and Retrieval System OnLINE

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