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  1. Article ; Online: Simpson's Paradox: Meta-Analysis Comparing Torsemide Versus Furosemide in Patients With Heart Failure.

    Baduashvili, Amiran

    The American journal of cardiology

    2020  Volume 125, Issue 8, Page(s) 1285

    MeSH term(s) Furosemide ; Heart Failure ; Humans ; Sodium Potassium Chloride Symporter Inhibitors ; Torsemide
    Chemical Substances Sodium Potassium Chloride Symporter Inhibitors ; Furosemide (7LXU5N7ZO5) ; Torsemide (W31X2H97FB)
    Language English
    Publishing date 2020-02-03
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2020.01.031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Considerations for Clinician-Educators Developing Online Educational Content: A Narrative Review.

    Baduashvili, Amiran / Fainstad, Brandon / Kudron, Elizabeth L

    Cureus

    2024  Volume 16, Issue 2, Page(s) e55048

    Abstract: In modern medical education, clinician-educators are increasingly called upon to develop online education to complement or replace in-person instruction. Despite a growing need for online curricula, many medical professionals lack training and experience ...

    Abstract In modern medical education, clinician-educators are increasingly called upon to develop online education to complement or replace in-person instruction. Despite a growing need for online curricula, many medical professionals lack training and experience in digital content development, deployment, assessment, and maintenance. Previous studies offer guidance on some aspects of online education development but often overlook key components, such as accessibility, legal considerations, financial implications, and sustainability challenges. This review offers medical professionals a broad overview of these important issues. We discuss various pedagogical considerations, including aligning educational goals and objectives with the digital content, choosing the appropriate online interface, and employing strategies to mitigate cognitive load while maximizing accessibility to create an inclusive online learning environment. We offer practical tips for creating effective, high-quality, and enduring audio-visual content and reflect on initial content deployment, testing, assessment, and revision. We discuss the intricacies of obtaining continuing medical education credits when the target audience includes faculty members. We address several legal issues online educators must consider, such as copyright laws, intellectual property rights, and medical liability. The review concludes with a discussion of sustainability mechanisms and financial considerations to ensure the long-term success of the educational program. Our recommendations aim to equip medical professionals embarking on a digital education journey with practical tools to produce effective, inclusive, and sustainable online content while considering legal implications.
    Language English
    Publishing date 2024-02-27
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.55048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Understanding the Shades of Gray in Diagnosis-An Online Course in Bayesian Reasoning.

    Baduashvili, Amiran / McBeth, Lauren / Baird, Andrew / Burden, Marisha

    Journal of graduate medical education

    2022  Volume 14, Issue 3, Page(s) 349–350

    MeSH term(s) Bayes Theorem ; Humans ; Internship and Residency ; Problem Solving
    Language English
    Publishing date 2022-06-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2578612-X
    ISSN 1949-8357 ; 1949-8357
    ISSN (online) 1949-8357
    ISSN 1949-8357
    DOI 10.4300/JGME-D-21-01029.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Dual Antithrombotic Therapy with Dabigatran after PCI in Atrial Fibrillation.

    Baduashvili, Amiran / Evans, Arthur T

    The New England journal of medicine

    2018  Volume 378, Issue 5, Page(s) 485

    MeSH term(s) Anticoagulants ; Atrial Fibrillation ; Dabigatran ; Fibrinolytic Agents ; Humans ; Percutaneous Coronary Intervention ; Stroke ; Warfarin
    Chemical Substances Anticoagulants ; Fibrinolytic Agents ; Warfarin (5Q7ZVV76EI) ; Dabigatran (I0VM4M70GC)
    Language English
    Publishing date 2018-03-22
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc1715183
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Cardiac Point-of-Care Ultrasound for the Diagnosis of Infective Endocarditis in a Patient with Non-Specific Rheumatologic Symptoms and Glomerulonephritis.

    Fischer, Brett G / Baduashvili, Amiran

    The American journal of case reports

    2019  Volume 20, Page(s) 542–547

    Abstract: BACKGROUND Point-of-care ultrasound (POCUS) is performed at the bedside by a healthcare professional who is directly caring for the patient. Subacute infective endocarditis can be challenging to diagnose, as patients often present with non-specific ... ...

    Abstract BACKGROUND Point-of-care ultrasound (POCUS) is performed at the bedside by a healthcare professional who is directly caring for the patient. Subacute infective endocarditis can be challenging to diagnose, as patients often present with non-specific symptoms. The modified Duke criteria include echocardiographic findings as a major criterion, but the role of POCUS has not been established. This report is of a case of infective endocarditis diagnosed using POCUS. CASE REPORT A 57-year-old man was admitted to hospital with a presumptive diagnosis of rapidly progressive glomerulonephritis secondary to vasculitis associated with a non-specific rheumatologic condition that had developed during the previous three months. Several specialist physicians had previously examined him. On hospital admission, POCUS was performed by the internal medicine physician, which showed mitral valve endocarditis resulting in a change in clinical management from steroid therapy to antibiotic therapy. Blood cultures were performed, which grew Streptococcus mutans. CONCLUSIONS To our knowledge, this is the first reported case of infective endocarditis diagnosed by an internist using POCUS in a patient admitted to hospital with an alternative diagnosis and management plan in place. This case highlights the potential role of POCUS in the acute hospital setting and supports the need for studies to compare the diagnostic performance of POCUS with transthoracic echocardiography for the detection of valvular vegetations. POCUS may be considered for patients with a possible diagnosis of infective endocarditis that cannot be excluded using the modified Duke criteria, potentially resulting in earlier diagnosis and management, with an improved clinical outcome.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Conservative Treatment ; Echocardiography, Doppler/methods ; Emergency Service, Hospital ; Endocarditis, Bacterial/complications ; Endocarditis, Bacterial/diagnostic imaging ; Follow-Up Studies ; Glomerulonephritis/complications ; Glomerulonephritis/diagnosis ; Humans ; Male ; Middle Aged ; Mitral Valve Stenosis/diagnostic imaging ; Mitral Valve Stenosis/drug therapy ; Mitral Valve Stenosis/microbiology ; Multimorbidity ; Point-of-Care Systems ; Rheumatic Diseases/complications ; Rheumatic Diseases/diagnosis ; Risk Assessment ; Streptococcal Infections/diagnosis ; Streptococcal Infections/drug therapy ; Streptococcus mutans/isolation & purification ; Stroke/etiology ; Stroke/therapy ; Treatment Outcome
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2019-04-18
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2517183-5
    ISSN 1941-5923 ; 1941-5923
    ISSN (online) 1941-5923
    ISSN 1941-5923
    DOI 10.12659/AJCR.914708
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Evaluation for Fibrosis After Cure of Hepatitis C.

    Fischer, Brett G / Baduashvili, Amiran / Evans, Arthur T

    JAMA

    2019  Volume 321, Issue 15, Page(s) 1534

    MeSH term(s) Elasticity Imaging Techniques ; Fibrosis ; Hepatitis C ; Humans ; Liver Cirrhosis ; Vibration
    Language English
    Publishing date 2019-04-19
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2019.0865
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: How to understand and teach P values: a diagnostic test framework.

    Baduashvili, Amiran / Evans, Arthur T / Cutler, Todd

    Journal of clinical epidemiology

    2020  Volume 122, Page(s) 49–55

    Abstract: Objectives: The aim of the tutorial is to help educators address misconceptions about P values and provide a tool that can be used to teach a more contemporary interpretation.: Study design and setting: A scripted tutorial using problem-based ... ...

    Abstract Objectives: The aim of the tutorial is to help educators address misconceptions about P values and provide a tool that can be used to teach a more contemporary interpretation.
    Study design and setting: A scripted tutorial using problem-based learning and a diagnostic test analogy to deconstruct the misunderstandings about P values and develop a more Bayesian approach to study interpretation.
    Results: A diagnostic test analogy is an effective teaching tool. Learners' understanding of Bayes' theorem in diagnostic testing can be used as a bridge to the realization that the prestudy probability of a true difference is crucial for study interpretation. The analogy has several caveats and shortcomings. The limitations of this analogy and the conceptual difficulties with the Bayesian study analyses are addressed.
    Conclusion: P values do not provide the information many assume they do-they are not equivalent to a probability of a chance finding. This tutorial helps move learners from these incorrect notions to new insights.
    MeSH term(s) Adult ; Bayes Theorem ; Biomedical Research/standards ; Clinical Decision-Making ; Data Interpretation, Statistical ; Diagnostic Tests, Routine/standards ; Female ; Guidelines as Topic ; Humans ; Male ; Middle Aged ; Probability ; Research Personnel/education
    Language English
    Publishing date 2020-03-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 639306-8
    ISSN 1878-5921 ; 0895-4356
    ISSN (online) 1878-5921
    ISSN 0895-4356
    DOI 10.1016/j.jclinepi.2020.03.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Frequency of Continuous Renal Replacement Therapy Use Early in Coronavirus Disease 2019 Pandemic.

    Baduashvili, Amiran / Oberle, Lauren P / Devitt, Jessica

    Critical care explorations

    2020  Volume 2, Issue 5, Page(s) e0129

    Abstract: Objectives: A subset of patients with coronavirus disease 2019 develop renal failure and require continuous renal replacement therapy. We reviewed the available literature to understand the frequency of continuous renal replacement therapy use among ... ...

    Abstract Objectives: A subset of patients with coronavirus disease 2019 develop renal failure and require continuous renal replacement therapy. We reviewed the available literature to understand the frequency of continuous renal replacement therapy use among patients with coronavirus disease 2019 who required intensive care.
    Data sources: The authors reviewed PubMed and Google Scholar for published studies and MedRxiv.com for unpublished studies.
    Study selection: Observational and randomized studies that report the frequency of continuous renal replacement therapy use in adult patients with coronavirus disease 2019.
    Data extraction: Data from the eligible studies were extracted independently by two authors into Microsoft Excel.
    Data synthesis: We identified 12 eligible studies (eight published, four unpublished). We found that up to 20% of patients admitted to ICUs may require continuous renal replacement therapy.
    Conclusions: Given the high utilization of continuous renal replacement therapy by critically ill patients with coronavirus disease 2019, there may be an urgent need to mobilize inpatient dialysis resources to cope with the anticipated increase in the demand.
    Keywords covid19
    Language English
    Publishing date 2020-05-14
    Publishing country United States
    Document type Journal Article
    ISSN 2639-8028
    ISSN (online) 2639-8028
    DOI 10.1097/CCE.0000000000000129
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Cold Agglutinins in Mycoplasma Infection.

    Fischer, Brett G / Baduashvili, Amiran / Evans, Arthur T

    JAMA

    2018  Volume 320, Issue 10, Page(s) 1038–1039

    MeSH term(s) Cold Temperature ; Cryoglobulins ; Humans ; Mycoplasma Infections
    Chemical Substances Cryoglobulins ; cold agglutinins
    Language English
    Publishing date 2018-09-11
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2018.9249
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Resident Burnout, Wellness, Professional Development, and Engagement Before and After New Training Schedule Implementation.

    Heppe, Daniel / Baduashvili, Amiran / Limes, Julia E / Suddarth, Katie / Mann, Adrienne / Gottenborg, Emily / Sacro, Yasmin / Davis, Lisa / Chacko, Karen / Connors, Geoffrey

    JAMA network open

    2024  Volume 7, Issue 2, Page(s) e240037

    Abstract: Importance: Burnout is a work-related syndrome of depersonalization (DP), emotional exhaustion (EE), and low personal achievement (PA) that is prevalent among internal medicine resident trainees. Prior interventions have had modest effects on resident ... ...

    Abstract Importance: Burnout is a work-related syndrome of depersonalization (DP), emotional exhaustion (EE), and low personal achievement (PA) that is prevalent among internal medicine resident trainees. Prior interventions have had modest effects on resident burnout. The association of a new 4 + 4 block schedule (4 inpatient weeks plus 4 outpatient weeks) with resident burnout has not previously been evaluated.
    Objective: To evaluate the association of a 4 + 4 block schedule, compared with a 4 + 1 schedule, with burnout, wellness, and self-reported professional engagement and clinical preparedness among resident physicians.
    Design, setting, and participants: This nonrandomized preintervention and postintervention survey study was conducted in a single academic-based internal medicine residency program from June 2019 to June 2021. The study included residents in the categorical, hospitalist, and primary care tracks in postgraduate years 1 and 2 (PGY1 and PGY2). Data analysis was conducted from October to December 2022.
    Intervention: In the 4 + 4 structure, resident schedules alternated between 4-week inpatient call-based rotations and 4-week ambulatory non-call-based rotations.
    Main outcomes and measures: The primary outcome was burnout, assessed using the Maslach Burnout Inventory subcategories of EE (range, 0-54), DP (range, 0-30), and PA (range, 0-48), adjusted for sex and PGY. Secondary outcomes included In-Training Examination (ITE) scores and a questionnaire on professional, educational, and health outcomes. Multivariable logistic regression was used to assess the primary outcome, 1-way analysis of variance was used to compare ITE percentiles, and a Bonferroni-adjusted Kruskal Wallis test was used for the remaining secondary outcomes. The findings were reexamined with several sensitivity analyses, and Cohen's D was used to estimate standardized mean differences (SMDs).
    Results: Of the 313 eligible residents, 216 completed the surveys. A total of 107 respondents (49.5%) were women and 109 (50.5%) were men; 119 (55.1%) were PGY1 residents. The survey response rates were 78.0% (85 of 109) in the preintervention cohort and 60.6% (63 of 104) and 68.0% (68 of 100) in the 2 postintervention cohorts. The PGY1 residents had higher response rates than the PGY2 residents (119 of 152 [78.2%] vs 97 of 161 [60.2%]; P < .001). Adjusted EE scores (mean difference [MD], -6.78 [95% CI, -9.24 to -4.32]) and adjusted DP scores (MD, -3.81 [95% CI, -5.29 to -2.34]) were lower in the combined postintervention cohort. The change in PA scores was not statistically significant (MD, 1.4 [95% CI, -0.49 to 3.29]). Of the 15 items exploring professional, educational, and health outcomes, a large positive association was observed for 11 items (SMDs >1.0). No statistically significant change in ITE percentile ranks was noted.
    Conclusions and relevance: In this survey study of internal medicine resident physicians, a positive association was observed between a 4 + 4 block training schedule and internal medicine resident burnout scores and improved self-reported professional, educational, and health outcomes. These results suggest that specific 4 + 4 block combinations may better improve resident burnout than a 4 + 1 combination used previously.
    MeSH term(s) Male ; Humans ; Female ; Burnout, Psychological ; Self Report ; Inservice Training ; Emotional Exhaustion ; Hospitalists ; Psychological Tests
    Language English
    Publishing date 2024-02-05
    Publishing country United States
    Document type Journal Article
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2024.0037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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