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  1. Article: Equity and Diversity in Behavior Analysis: Lessons From Skinner (1945).

    Szabo, Thomas G

    Behavior analysis in practice

    2020  Volume 13, Issue 2, Page(s) 375–386

    Abstract: Several authors have written about the disparity between our values statements concerning gender equity and diversity and the behavior of our professional organizations. In this article, I argue that this is a predictable by-product of our collective ... ...

    Abstract Several authors have written about the disparity between our values statements concerning gender equity and diversity and the behavior of our professional organizations. In this article, I argue that this is a predictable by-product of our collective cultural learning histories, that we have access to the variables that must be manipulated to alter this behavioral trajectory, and that now is the time to apply the principles of behavior toward changing our current repertoire. As a case in point, I provide evidence regarding the current state of the efforts within psychology and behavior analysis to ensure gender equity, and end with a series of recommendations for institutions and individual leaders to enact toward the presumably valued outcomes of equity and, more broadly speaking, diversity.
    Language English
    Publishing date 2020-03-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2583900-7
    ISSN 2196-8934 ; 1998-1929
    ISSN (online) 2196-8934
    ISSN 1998-1929
    DOI 10.1007/s40617-020-00414-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: First experience with the new extracorporeal membrane oxygenation system Colibrì.

    Saemann, Lars / Stiller, Markus / Willsch, Jan / Schultze, Thomas / Matin, Meradjoddin / Veres, Gábor / Szabó, Gábor

    Artificial organs

    2023  Volume 48, Issue 1, Page(s) 103–109

    Abstract: Introduction: Extracorporeal membrane oxygenation (ECMO) is increasingly used for circulatory or pulmonary support not only in-hospital but also out-of-hospital. Small dimensions and a lightweight design are important, especially for out-of-hospital use ...

    Abstract Introduction: Extracorporeal membrane oxygenation (ECMO) is increasingly used for circulatory or pulmonary support not only in-hospital but also out-of-hospital. Small dimensions and a lightweight design are important, especially for out-of-hospital use but also for intra-hospital transportation of patients who require ECMO support. We share our first experience with the new Colibrì ECMO system.
    Patients and methods: From December 2022 to January 2023, we used the new Colibrì extracorporeal circulation (ECC) system in six patients with cardiac or pulmonary failure.
    Results: The Colibrì system was used in-hospital in six patients with post-cardiac surgery low output syndrome, respiratory failure due to influenza or acute respiratory distress syndrome, cardiogenic shock, pulmonary embolism, and failed weaning from cardiopulmonary bypass. The system was implanted in venovenous (VV) and venoarterial (VA) fashion in 3 patients, respectively. In one patient, the configuration was switched from VA to VV after cardiac recovery. One patient received left-ventricular unloading using the IMPELLA®5.5. ECMO run time was 1 to 13 days. We did not notice any ECC system-associated complications. No ECMO system changes were required.
    Conclusion: Our case series concludes that the new Colibrì system is safe and effective for in-hospital ECMO indications. The small dimensions and lightweight design are very beneficial for the transportation of patients. It might be especially helpful for out-of-hospital situations.
    MeSH term(s) Humans ; Extracorporeal Membrane Oxygenation/adverse effects ; Extracorporeal Membrane Oxygenation/methods ; Shock, Cardiogenic/therapy ; Respiratory Distress Syndrome/therapy ; Respiratory Insufficiency/therapy ; Heart ; Retrospective Studies
    Language English
    Publishing date 2023-11-23
    Publishing country United States
    Document type Case Reports
    ZDB-ID 441812-8
    ISSN 1525-1594 ; 0160-564X
    ISSN (online) 1525-1594
    ISSN 0160-564X
    DOI 10.1111/aor.14671
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Online ACT Matrix Parent Training for Japanese-Speaking Mothers with Distress in the United States.

    Kurumiya, Yukie / Garcia, Yors / Griffith, Annette K / Szabo, Thomas G

    Journal of child and family studies

    2022  Volume 31, Issue 12, Page(s) 3514–3532

    Abstract: Cultural stigma, shame, self-concealment, and language and socio-economic barriers often keep Asian immigrant parents and children away from mental and behavioral services in the United States. Research shows that increased levels of parent distress ... ...

    Abstract Cultural stigma, shame, self-concealment, and language and socio-economic barriers often keep Asian immigrant parents and children away from mental and behavioral services in the United States. Research shows that increased levels of parent distress suggest a negative impact on parenting practices and correlate child-maltreatment. Therefore, this study aimed to test one functionally contextual strategy to address such issues. The current study evaluated the effects of an online Acceptance and Commitment Training (ACT) Matrix for Japanese-speaking mothers living the United States. A nonconcurrent multiple baseline single-subject design across four mothers was used to assess the effect of ACT Matrix on value-driven behaviors, parental engagement (session attendance and daily assignment completion), parental distress, and psychological flexibility. The study consisted of a baseline, treatment (three ACT Matrix treatment sessions adapted from the six-step protocol), maintenance, and follow-up phases. A visual analysis reporting level, trend, variability, immediacy of change and overlap was used to identify a functional relation between the treatment and observable overt behaviors of value-driven behaviors and daily assignment completion. In addition, a non-overlap of all pairs was used to measure effect sizes for these behaviors. For psychological flexibility and parental distress, we used the reliable change index to assess whether clinically significant improvement occurred or not. The results revealed that the online ACT Matrix parent training program was effective in improving all four dependent variables. Mothers reported that the training was culturally sensitive, effective, and acceptable. The details of findings and the implications for future research as preventive science are discussed.
    Language English
    Publishing date 2022-11-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2016750-7
    ISSN 1573-2843 ; 1062-1024
    ISSN (online) 1573-2843
    ISSN 1062-1024
    DOI 10.1007/s10826-022-02477-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Acceptance and Commitment Training Within the Scope of Practice of Applied Behavior Analysis.

    Tarbox, Jonathan / Szabo, Thomas G / Aclan, Megan

    Behavior analysis in practice

    2020  Volume 15, Issue 1, Page(s) 11–32

    Abstract: Acceptance and commitment therapy (ACT) is a contemporary behavior-analytic approach to intervening on verbal behavior for the purposes of bringing about socially meaningful overt behavior change. Although originally developed as a behavior-analytic ... ...

    Abstract Acceptance and commitment therapy (ACT) is a contemporary behavior-analytic approach to intervening on verbal behavior for the purposes of bringing about socially meaningful overt behavior change. Although originally developed as a behavior-analytic approach to psychotherapy, the conceptual functional analyses and procedures that form the core of ACT have been disseminated broadly outside of clinical psychology, including within the field of applied behavior analysis (ABA). This article discusses the use of ACT within mainstream ABA practice and provides preliminary conceptual functional analyses and practical guidelines for incorporating ACT within the scope of practice of applied behavior analysts.
    Language English
    Publishing date 2020-08-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2583900-7
    ISSN 2196-8934 ; 1998-1929
    ISSN (online) 2196-8934
    ISSN 1998-1929
    DOI 10.1007/s40617-020-00466-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The miR-15a/16-1 and miR-15b/16-2 clusters regulate early B cell development by limiting IL-7 receptor expression.

    Hutter, Katharina / Rülicke, Thomas / Szabo, Tamas G / Andersen, Lill / Villunger, Andreas / Herzog, Sebastian

    Frontiers in immunology

    2022  Volume 13, Page(s) 967914

    Abstract: MicroRNAs are small non-coding RNAs that have emerged as post-transcriptional regulators involved in development and function of different types of immune cells, and aberrant miRNA expression has often been linked to cancer. One prominent miRNA family in ...

    Abstract MicroRNAs are small non-coding RNAs that have emerged as post-transcriptional regulators involved in development and function of different types of immune cells, and aberrant miRNA expression has often been linked to cancer. One prominent miRNA family in the latter setting is the miR-15 family, consisting of the three clusters miR-15a/16-1, miR-15b/16-2 and miR-497/195, which is best known for its prominent tumor suppressive role in chronic lymphocytic leukemia (CLL). However, little is known about the physiological role of the miR-15 family. In this study, we provide a comprehensive
    MeSH term(s) Cell Proliferation/genetics ; MicroRNAs/metabolism ; Phosphatidylinositol 3-Kinases ; Proto-Oncogene Proteins c-akt ; Receptors, Interleukin-7/genetics
    Chemical Substances MicroRNAs ; Receptors, Interleukin-7 ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1)
    Language English
    Publishing date 2022-08-25
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2022.967914
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The effects of fumonisin B

    Szabó, András / Omeralfaroug, Ali / Bjellaas, Thomas / Kövér, György / Turbók, Janka / Kovács, Melinda

    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

    2022  , Page(s) 113333

    Abstract: Fumonisin ... ...

    Abstract Fumonisin B
    Language English
    Publishing date 2022-08-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 782617-5
    ISSN 1873-6351 ; 0278-6915
    ISSN (online) 1873-6351
    ISSN 0278-6915
    DOI 10.1016/j.fct.2022.113333
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Investigation of the Variability of Alkaloids in Buxus sempervirens L. Using Multivariate Data Analysis of LC/MS Profiles

    Lara U. Szabó / Thomas J. Schmidt

    Molecules, Vol 27, Iss 82, p

    2022  Volume 82

    Abstract: ... their organs (leaf vs. twig) of B . sempervirens . Thus, the results of this study allow, e.g ...

    Abstract Buxus sempervirens L. is a common ornamental plant in southern and central Europe, and has been used ethopharmacologically against a wide variety of diseases due to it containing nor -triterpene alkaloids of the nor -cycloartane type. Recently, we demonstrated the interesting antiprotozoal potential of some of these compounds. To characterize the temporal variability in the alkaloid profile of two different varieties and their leaves and twigs, 30 different extracts of B . sempervirens were evaluated by Ultra High Performance Liquid Chromatography/positive Mode-Electrospray Ionization Quadrupole Time-of-Flight-Tandem Mass Spectrometry (UHPLC/+ESI-QqTOF-MS/MS). The analytical profiles were thoroughly investigated by various methods of multivariate data analysis (MVDA). A principal component analysis (PCA) model elucidates the seasonal variation in the phytochemical composition of B . sempervirens var. arborescens and suffruticosa along with differences between the varieties. Analysis of a volcano plot illustrated the differences between the two organs, the leaf and twig. Eighteen compounds were highlighted by the models as constituents of the plant characteristic for a season, variety or organ. These compounds were dereplicated based on their chromatographic and +ESI-QqTOF-MS and –MS/MS data. In addition, mass spectral fragmentation pathways for already known alkaloids as well as new natural products could be postulated for the first time. In conclusion, the MVDA models give detailed information on the temporal variability in the alkaloid profile of two different varieties and their organs (leaf vs. twig) of B . sempervirens . Thus, the results of this study allow, e.g., the identification of characteristic compounds for the different varieties, plant organs, seasons, and the optimal harvesting time for the isolation of particular Buxus -alkaloids of interest for subsequent studies.
    Keywords Buxus sempervirens L ; nor -cycloartane alkaloids ; seasonal variability ; optimal harvesting time ; multivariate data analysis ; principal component analysis ; Organic chemistry ; QD241-441
    Subject code 540
    Language English
    Publishing date 2022-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: From Helpless to Hero: Promoting Values-Based Behavior and Positive Family Interaction in the Midst of COVID-19.

    Szabo, Thomas G / Richling, Sarah / Embry, Dennis D / Biglan, Anthony / Wilson, Kelly G

    Behavior analysis in practice

    2020  Volume 13, Issue 3, Page(s) 568–576

    Abstract: Parents managing their home environments during government-ordered stay-at-home periods are likely to need new skills for occupying their children's time with activities that promote health and emotional well-being. Moreover, parents and children know ... ...

    Abstract Parents managing their home environments during government-ordered stay-at-home periods are likely to need new skills for occupying their children's time with activities that promote health and emotional well-being. Moreover, parents and children know they need help managing these circumstances. Perhaps for the first time, behavior analysts hold the reinforcers for increasing parental involvement in effective child-rearing practices. In fact, behavior analysts can help parents enlist their children in managing the household by framing their behavior in terms of hidden superpowers. In the current article, we argue that behavior analysts have a range of tools to offer that are grounded in evidence-based principles, strategies, and kernels-or essential units of behavioral influence. When combined into scheduled daily practices and invoked by children taught to see their use of the tools as nothing short of heroic, these practices function as "vaccinations" that inoculate families against toxic and unsafe behaviors.
    Keywords covid19
    Language English
    Publishing date 2020-04-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2583900-7
    ISSN 2196-8934 ; 1998-1929
    ISSN (online) 2196-8934
    ISSN 1998-1929
    DOI 10.1007/s40617-020-00431-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Prevention of Chronic Morbidities in Extremely Premature Newborns with LISA-nCPAP Respiratory Therapy and Adjuvant Perinatal Strategies.

    Balázs, Gergely / Balajthy, András / Seri, István / Hegyi, Thomas / Ertl, Tibor / Szabó, Tamás / Röszer, Tamás / Papp, Ágnes / Balla, József / Gáll, Tamás / Balla, György

    Antioxidants (Basel, Switzerland)

    2023  Volume 12, Issue 6

    Abstract: Less invasive surfactant administration techniques, together with nasal continuous airway pressure (LISA-nCPAP) ventilation, an emerging noninvasive ventilation (NIV) technique in neonatology, are gaining more significance, even in extremely premature ... ...

    Abstract Less invasive surfactant administration techniques, together with nasal continuous airway pressure (LISA-nCPAP) ventilation, an emerging noninvasive ventilation (NIV) technique in neonatology, are gaining more significance, even in extremely premature newborns (ELBW), under 27 weeks of gestational age. In this review, studies on LISA-nCPAP are compiled with an emphasis on short- and long-term morbidities associated with prematurity. Several perinatal preventative and therapeutic investigations are also discussed in order to start integrated therapies as numerous organ-saving techniques in addition to lung-protective ventilations. Two thirds of immature newborns can start their lives on NIV, and one third of them never need mechanical ventilation. With adjuvant intervention, these ratios are expected to be increased, resulting in better outcomes. Optimized cardiopulmonary transition, especially physiologic cord clamping, could have an additively beneficial effect on patient outcomes gained from NIV. Organ development and angiogenesis are strictly linked not only in the immature lung and retina, but also possibly in the kidney, and optimized interventions using angiogenic growth factors could lead to better morbidity-free survival. Corticosteroids, caffeine, insulin, thyroid hormones, antioxidants, N-acetylcysteine, and, moreover, the immunomodulatory components of mother's milk are also discussed as adjuvant treatments, since immature newborns deserve more complex neonatal interventions.
    Language English
    Publishing date 2023-05-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2704216-9
    ISSN 2076-3921
    ISSN 2076-3921
    DOI 10.3390/antiox12061149
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Beyond the three P's: adrenal involvement in MEN1.

    Clemente-Gutierrez, Uriel / Pieterman, Carolina R C / Lui, Michael S / Yamashita, Thomas Szabo / Tame-Elorduy, Andrés / Huang, Bernice L / Shirali, Aditya S / Erstad, Derek J / Lee, Jeffrey E / Fisher, Sarah B / Graham, Paul H / Grubbs, Elizabeth G / Waguespack, Steven G / Ng, Chaan S / Perrier, Nancy

    Endocrine-related cancer

    2024  Volume 31, Issue 2

    Abstract: Adrenal lesions (ALs) are often detected in patients with multiple endocrine neoplasia type 1 (MEN1). However, they are not well described in MEN1, making their clinical management unclear. This study examined the prevalence and outcomes of ALs found in ... ...

    Abstract Adrenal lesions (ALs) are often detected in patients with multiple endocrine neoplasia type 1 (MEN1). However, they are not well described in MEN1, making their clinical management unclear. This study examined the prevalence and outcomes of ALs found in MEN1. We performed a retrospective chart review of patients diagnosed with MEN1 from 1990 to 2021. ALs were diagnosed using abdominal or thoracic imaging and classified as being unilateral or bilateral, having single or multiple nodules, and as having diffuse enlargement or not. Measurable nodular lesions were analyzed for their size and growth over time. Patients' clinical and radiographic characteristics were collected. We identified 382 patients with MEN1, 89 (23.3%) of whom had ALs. The mean age at detection was 47 ± 11.9 years. We documented 101 measurable nodular lesions (mean size, 17.5 mm; range, 3-123 mm). Twenty-seven nodules (26.7%) were smaller than 1 cm. Watchful waiting was indicated in 79 (78.2%) patients, of whom 28 (35.4%) had growing lesions. Functional lesions were diagnosed in 6 (15.8%) of 38 that had functional work-up (diagnoses: pheochromocytoma (n = 2), adrenocorticotropic hormone-dependent hypercortisolism (n = 2), hyperandrogenism (n = 1), hyperaldosteronism (n = 1)); surgery was indicated for 5 (83.3%; n = 12 nodules), 2 of whom had bilateral, diffuse adrenal enlargement. Two patients were diagnosed with adrenocortical carcinoma and two with neoplasms of uncertain malignant potential. Radiographic or clinical progression of ALs is uncommon. Malignancy should be suspected on the basis of a lesion's growth rate and size. A baseline hormonal work-up is recommended, and no further biochemical work-up is suggested when the initial assessment shows nonfunctioning lesions.
    MeSH term(s) Humans ; Adult ; Middle Aged ; Multiple Endocrine Neoplasia Type 1/pathology ; Retrospective Studies ; Adrenal Gland Neoplasms/epidemiology ; Adrenocortical Carcinoma ; Adrenal Cortex Neoplasms
    Language English
    Publishing date 2024-01-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 1218450-0
    ISSN 1479-6821 ; 1351-0088
    ISSN (online) 1479-6821
    ISSN 1351-0088
    DOI 10.1530/ERC-23-0162
    Database MEDical Literature Analysis and Retrieval System OnLINE

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