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  1. Article: Drug-Induced Acute Pancreatitis and Pseudoaneurysms: An Ominous Combination.

    Branquinho, Diogo / Ramos-Andrade, Daniel / Elvas, Luís / Amaro, Pedro / Ferreira, Manuela / Sofia, Carlos

    GE Portuguese journal of gastroenterology

    2016  Volume 23, Issue 6, Page(s) 309–313

    Abstract: Rupture of pseudoaneurysms is rare but can be life-threatening complications of acute or chronic pancreatitis, usually due to enzymatic digestion of vessel walls crossing peripancreatic fluid collections. We report the case of a 40 year-old female, with ... ...

    Abstract Rupture of pseudoaneurysms is rare but can be life-threatening complications of acute or chronic pancreatitis, usually due to enzymatic digestion of vessel walls crossing peripancreatic fluid collections. We report the case of a 40 year-old female, with multisystemic lupus and anticoagulated for prior thrombotic events, admitted for probable cyclosporine-induced acute pancreatitis. Hemodynamic instability occurred due to abdominal hemorrhage from two pseudoaneurysms inside an acute peri-pancreatic collection. Selective angiography successfully embolized the gastroduodenal and pancreatoduodenal arteries. The hemorrhage recurred two weeks later and another successful embolization was performed and the patient remains well to date. The decision to restart anticoagulants and to suspend cyclosporine was challenging and required a multidisciplinary approach. Despite rare, bleeding from a pseudoaneurysm should be considered when facing a patient with pancreatitis and sudden signs of hemodynamic instability.
    Language English
    Publishing date 2016-08-12
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2835774-7
    ISSN 2387-1954 ; 2341-4545
    ISSN (online) 2387-1954
    ISSN 2341-4545
    DOI 10.1016/j.jpge.2016.06.002
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  2. Article ; Online: From past sailors' eras to the present day: scurvy as a surprising manifestation of an uncommon gastrointestinal disease.

    Branquinho, Diogo Ferreira / Pinto-Gouveia, Miguel / Mendes, Sofia / Sofia, Carlos

    BMJ case reports

    2015  Volume 2015

    Abstract: A 45-year-old man presented with follicular exanthema in his lower limbs, alternating bowel habits and significant weight loss. His medical history included seronegative arthritis, bipolar disease and an inconclusive diagnostic laparoscopy. Diagnostic ... ...

    Abstract A 45-year-old man presented with follicular exanthema in his lower limbs, alternating bowel habits and significant weight loss. His medical history included seronegative arthritis, bipolar disease and an inconclusive diagnostic laparoscopy. Diagnostic work up revealed microcytic anaemia and multivitamin deficiency. Skin biopsy of the exanthema suggested scurvy. Owing to these signs of malabsorption, upper endoscopy with duodenal biopsies was performed, exhibiting villous atrophy and extensive periodic acid-Schiff-positive material in the lamina propria, therefore diagnosing Whipple's disease (WD). After starting treatment with ceftriaxone and co-trimoxazole, an impressive recovery was noted, as the wide spectrum of malabsorption signs quickly disappeared. After a year of antibiotics, articular and cutaneous manifestations improved, allowing the patient to stop taking corticosteroids and antidepressants. This truly unusual presentation reflects the multisystemic nature of WD, often leading to misdiagnosis of other entities. Scurvy is a rare finding in developed countries, but its presence should raise suspicion for small bowel disease.
    MeSH term(s) Anti-Bacterial Agents/administration & dosage ; Biopsy ; Ceftriaxone/administration & dosage ; Diagnostic Errors ; Exanthema/pathology ; Follow-Up Studies ; Humans ; Middle Aged ; Scurvy/diagnosis ; Scurvy/drug therapy ; Scurvy/pathology ; Skin/pathology ; Treatment Outcome ; Trimethoprim, Sulfamethoxazole Drug Combination/administration & dosage ; Tropheryma/isolation & purification ; Whipple Disease/diagnosis ; Whipple Disease/drug therapy ; Whipple Disease/microbiology ; Whipple Disease/pathology
    Chemical Substances Anti-Bacterial Agents ; Ceftriaxone (75J73V1629) ; Trimethoprim, Sulfamethoxazole Drug Combination (8064-90-2)
    Language English
    Publishing date 2015-09-16
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2015-210744
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  3. Article ; Online: The Association between Training Frequency, Symptoms of Overtraining and Injuries in Young Men Soccer Players.

    Rodrigues, Filipe / Monteiro, Diogo / Ferraz, Ricardo / Branquinho, Luís / Forte, Pedro

    International journal of environmental research and public health

    2023  Volume 20, Issue 8

    Abstract: Overtraining is a prevalent issue among young men soccer players, particularly those who are driven to enhance their skills. While an intense training volume and effort might contribute to athletic growth, it can also have negative implications, ... ...

    Abstract Overtraining is a prevalent issue among young men soccer players, particularly those who are driven to enhance their skills. While an intense training volume and effort might contribute to athletic growth, it can also have negative implications, including injury. The current study aimed at examining the association between training frequency, symptoms of overtraining and injuries in young men soccer players. A path analysis approach was used to examine the causal relationships between variables. The sample consisted of 189 young men soccer players aged 13-17 years old (age = 14.81, SD = 1.37). Participants reported that they were training, on average, 5.77 days (SD = 1.53) per week. Athletes were competing at a regional (n = 100) or national (n = 89) level. Concerning injuries, participants indicated, on average, 2.03 (SD = 1.16) injuries since they started practicing soccer. The results displayed a significant association, as theoretically expected, namely: (i) training frequency was significantly associated with overtraining symptoms (β = 0.15 [IC95% = 0.01, 0.29]); (ii) overtraining symptoms were significantly associated with the number of injuries (β = 0.19 [IC95% = 0.02, 0.35]). An indirect effect between training frequency and injuries was also observed (β = 0.15 [IC95% = 0.01, 0.29]). Thus, there is preliminary evidence that overtraining symptoms could play a mediating role. In conclusion, investigating the links between overtraining symptoms and injury in young men soccer players is critical, as it can assist in identifying overtraining warning signs, promote young players' health and safety, customize training regimens to individual needs, and contribute to a better understanding of sports-related injuries.
    MeSH term(s) Male ; Humans ; Adolescent ; Soccer/injuries ; Athletic Injuries/epidemiology ; Athletes
    Language English
    Publishing date 2023-04-11
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph20085466
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  4. Article ; Online: Mediastinitis by Actinomyces meyeri after oesophageal stent placement.

    Branquinho, Diogo Ferreira / Andrade, Daniel Ramos / Almeida, Nuno / Sofia, Carlos

    BMJ case reports

    2014  Volume 2014

    Abstract: Actinomyces meyeri is a Gram-positive anaerobic forming bacterium of the genus Actinomyces, part of the oral cavity's flora, and its classification remains an unresolved issue. It is an extremely rare cause of disease, occurring in middle-aged ... ...

    Abstract Actinomyces meyeri is a Gram-positive anaerobic forming bacterium of the genus Actinomyces, part of the oral cavity's flora, and its classification remains an unresolved issue. It is an extremely rare cause of disease, occurring in middle-aged immunocompetent patients and frequently misdiagnosed as malignancy or lung abscess. A 56-year-old man diagnosed with oesophageal squamous cell carcinoma had an endoscopically placed stent to palliate his dysphagia. Two weeks later he presented with thoracalgia and fever, interpreted as a common lung infection. Owing to lack of improvement, additional examinations were undertaken revealing mediastinum involvement. Unlike the good prognosis usually associated with this infection, the patient eventually died, reflecting the aggressive nature of his underlying condition. To our knowledge, this is the first report of mediastinitis by A. meyeri, supporting the described propensity of this agent to disseminate, particularly to the thoracic cavity, although probably in this case with an iatrogenic contribution.
    MeSH term(s) Actinomyces ; Actinomycosis/etiology ; Carcinoma, Squamous Cell/surgery ; Esophageal Diseases/etiology ; Esophageal Diseases/microbiology ; Esophageal Neoplasms/surgery ; Fatal Outcome ; Humans ; Male ; Mediastinitis/etiology ; Mediastinitis/microbiology ; Middle Aged ; Prosthesis-Related Infections/etiology ; Prosthesis-Related Infections/microbiology ; Stents/adverse effects
    Language English
    Publishing date 2014-06-05
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2014-204499
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  5. Article ; Online: Comparison of force variables and dynamic strength index between age groups in elite young Brazilian football goalkeepers.

    Portella, Daniel L / Jatene, Pedro / Da Silva, Alex O / Dos Santos, Gustavo S / Monteiro, Diogo / Teixeira, José E / Branquinho, Luís / Ferraz, Ricardo / Forte, Pedro

    Frontiers in sports and active living

    2024  Volume 6, Page(s) 1282214

    Abstract: Introduction: The application of muscle force is a determinant of football success as it is inherent to the motor control and sport. The aims of this study are: (1) to describe force variables Isometric Maximal Force (IMF), Concentric Peak Force (CPPF), ...

    Abstract Introduction: The application of muscle force is a determinant of football success as it is inherent to the motor control and sport. The aims of this study are: (1) to describe force variables Isometric Maximal Force (IMF), Concentric Peak Force (CPPF), and Dynamic Strength Index (DSI) in football goalkeepers from different age groups; (2) to compare these variables' behavior between those groups.
    Methods: The sample was formed by 19 youth players (15.97 ± 1.55 years old) from a first-division Brazilian football team. The CPPF and IMF variables were obtained through the Countermovement jump and isometric squat tests, respectively. For data collection, a force plate (Cefise, Brazil) was used with an acquisition frequency of 600 Hz and mono-axial. The DSI was calculated using the ratio between CPPF and IMF. For data analysis, the sample was separated into clusters by age. After the grouping, a descriptive analysis of the data and a comparison between the groups with
    Results: The sample was grouped into three groups (GA, GB, and GC) and one of the individuals did not enter the group, totaling 18 individuals in the analyzed sample. The comparison between the ages of the groups showed a significant difference and small and moderate effect size (ES), validating the cluster strategy. The CPPF and IMF variables showed increased values according to chronological age. CPPF showed a significant difference between GA-GB, (ES = very large) GA-GC (ES = very large), and GB-GC (ES = moderate). The IMF variable had significant differences between GA-GB (ES = moderate) and GA-GC (ES = very large). However, DSI showed significant differences only between GA GB (ES = small) and GB-GC (ES = very large).
    Conclusions: The CPPF and IMF variables had constant increases and distinct values with an increase according to age, and this did not occur for DSI. The difference between CPPF and IMF compared to DSI bring to light the variability in dynamics and proportionality between muscular force in the concentric phase and maximal force in the isometric regime during the developmental process over chronological age in soccer goalkeepers.
    Language English
    Publishing date 2024-01-26
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2624-9367
    ISSN (online) 2624-9367
    DOI 10.3389/fspor.2024.1282214
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  6. Article ; Online: Acute Effects of Heavy Strength Training on Mechanical, Hemodynamic, Metabolic, and Psychophysiological Parameters in Young Adult Males.

    Andrade, João / Esteves, Dulce / Ferraz, Ricardo / Marques, Diogo Luís / Branquinho, Luís / Marinho, Daniel Almeida / Marques, Mário Cardoso / Neiva, Henrique Pereira

    Sports (Basel, Switzerland)

    2022  Volume 10, Issue 12

    Abstract: This study analyzed the acute effects of heavy strength training on mechanical, hemodynamic, metabolic, and psychophysiological responses in adult males. Thirteen recreational level males (23.3 ± 1.5 years) randomly performed two heavy strength training ... ...

    Abstract This study analyzed the acute effects of heavy strength training on mechanical, hemodynamic, metabolic, and psychophysiological responses in adult males. Thirteen recreational level males (23.3 ± 1.5 years) randomly performed two heavy strength training sessions (3 sets of 8 repetitions at 80% of one repetition maximum [1RM]) using the bench press (HST-BP) or full squat (HST-FS)). The repetition velocity was recorded in both sessions. Moreover, before and after the sessions, the velocity attained against the ~1.00 m·s−1 load (V1Load) in the HST-BP, countermovement jump (CMJ) height in the HST-FS, blood pressure, heart rate, blood lactate, and psychophysiological responses (OMNI Perceived Exertion Scale for Resistance Exercise) were measured. There were differences between exercises in the number of repetitions performed in the first and third sets (both <8 repetitions). The velocity loss was higher in the HST-BP than in the HST-FS (50.8 ± 10.0% vs. 30.7 ± 9.5%; p < 0.001). However, the mechanical fatigue (V1Load vs. CMJ height) and the psychophysiological response did not differ between sessions (p > 0.05). The HST-FS caused higher blood pressure and heart rate responses than the HST-BP (p < 0.001 and p = 0.02, respectively) and greater blood lactate changes from pre-training to post-set 1 (p < 0.05). These results showed that the number of maximal repetitions performed in both sessions was lower than the target number and decreased across sets. Moreover, the HST-BP caused a higher velocity loss than the HST-FS. Finally, the HST-FS elicited higher hemodynamic and metabolic demand than the HST-BP.
    Language English
    Publishing date 2022-11-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704239-X
    ISSN 2075-4663 ; 2075-4663
    ISSN (online) 2075-4663
    ISSN 2075-4663
    DOI 10.3390/sports10120195
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  7. Article ; Online: Validation of the Ottawa ankle rules: Strategies for increasing specificity.

    Morais, Bruno / Branquinho, André / Barreira, Mariana / Correia, Joana / Machado, Marino / Marques, Nuno / Ferrão, Ana / Nóbrega, João / Teixeira, Frederico / Diogo, Nuno

    Injury

    2021  Volume 52, Issue 4, Page(s) 1017–1022

    Abstract: Introduction: The majority of patients with ankle injuries undergo radiological examinations of the foot, ankle or both. The objective of this study was in the first place to validate the Ottawa Ankle Rules (OARs) for the population of our centre. ... ...

    Abstract Introduction: The majority of patients with ankle injuries undergo radiological examinations of the foot, ankle or both. The objective of this study was in the first place to validate the Ottawa Ankle Rules (OARs) for the population of our centre. Secondly, an attempt was made to identify parameters that contribute to improve the specificity of the method, with a view to reduce the need for patients to be exposed to radiation as well as optimizing the expenses of the Emergency Ward (EW).
    Materials and methods: This was a prospective study conducted during a 9-month period. The study population included 148 patients, in 54 (36%) of the patients a fracture was present on the exams performed. Patients were submitted to a sequential protocol in the EW with a form completion, evaluation of OARs, application of the Visual Analog Pain Scale (VAS) and radiographic exams.
    Results: We found a sensitivity of OARs in ankle injuries of 100%, specificity of 26% and in midfoot injuries of 100% and 62% respectively. All patients with fractures had a VAS of 5 or more points in any of the tested sites. With the VAS criterium, we found a significant increase of global specificity (38% vs 15%), as well as when applied only to the ankle (26% to 47%) or to midfoot trauma (62% to 67%). In both, there would have been a 100% reduction of CT scans. Patients with a fracture or with fractures who required surgical treatment had a mean VAS significantly higher than patients with no fracture or fractures submitted to conservative treatment respectively. Although there was a lower percentage of fractures in the group of injuries in Work Accidents (31% vs 37% Sports Activity and 38% Leisure Activity), there was a statistically significant increase in the sum of average VAS in Accidents at Work vs Leisure Activities and vs Sports Activities.
    Conclusion: We seek to confirm the usefulness of OARs for our population and we investigated strategies to further reduce the need for unnecessary radiographs. The introduction of parameters for grading pain and adapting to the context of the accident seem promising.
    MeSH term(s) Ankle ; Ankle Injuries/diagnostic imaging ; Foot Injuries/diagnostic imaging ; Fractures, Bone/diagnostic imaging ; Humans ; Prospective Studies ; Sensitivity and Specificity
    Language English
    Publishing date 2021-01-10
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 218778-4
    ISSN 1879-0267 ; 0020-1383
    ISSN (online) 1879-0267
    ISSN 0020-1383
    DOI 10.1016/j.injury.2021.01.006
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