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Article ; Online: Investigation of heavy metals in tissues and habitats of three edible frogs from Türkiye.

Tatlı, Hale / Gedik, Kenan / Altunışık, Abdullah

Environmental science and pollution research international

2024 Volume 31, Issue 5, Page(s) 7806–7817

Abstract: ... calculated based on the average serving size, were also lower than the Provisional Tolerable Daily Intake ...

Abstract	The soil, water, and organisms have been contaminated by heavy metals due to human activities and industrialization, which has produced a major environmental problem that has a deleterious effect on human health and food quality. Frogs, one of the good bioindicators for environmental pollution, are also among the alternative essential protein sources for humans. In Türkiye, three of these frogs are edible: Pelophylax ridibundus, Pelophylax bedriagae, and Pelophylax caralitanus, also known as Anatolian water frogs. Hence, to assess the possible health risks that might result from consuming frog legs in addition aquatic habitat of Anatolian water frogs, the water, sediment, and frog tissue samples (muscle and liver) were obtained from 11 different provinces covering all regions of Türkiye and analyzed to determine Cd, Cu, Cr, Zn, Pb, and As concentrations. The results revealed considerable variations in heavy metal concentrations among frog tissues, influenced by the sampling sites and species (ANOVA: p < 0.05). The Estimated Daily Intake (EDI) values, calculated based on the average serving size, were also lower than the Provisional Tolerable Daily Intake (PTDI) levels for adult consumers. Furthermore, the study computed the Target Hazard Quotient (THQ) values for heavy metals, all of which were below the critical value of 1, indicating that consuming the hind leg muscles from these frog species would not pose an adverse health risk for humans.
MeSH term(s)	Animals ; Adult ; Humans ; Turkey ; Metals, Heavy/analysis ; Ranidae ; Environmental Monitoring ; Ecosystem ; Muscle, Skeletal/metabolism ; Water/metabolism ; Risk Assessment ; Water Pollutants, Chemical/analysis
Chemical Substances	Metals, Heavy ; Water (059QF0KO0R) ; Water Pollutants, Chemical
Language	English
Publishing date	2024-01-03
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-023-31226-9
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Article ; Online: Cross-sectional imaging of congenital and acquired abnormalities of the portal venous system.

Özbayrak, Mustafa / Tatlı, Servet

Diagnostic and interventional radiology (Ankara, Turkey)

2016 Volume 22, Issue 6, Page(s) 501–507

Abstract: Knowing the normal anatomy, variations, congenital and acquired pathologies of the portal venous system are important, especially when planning liver surgery and percutaneous interventional procedures. The portal venous system pathologies can be ... ...

Abstract	Knowing the normal anatomy, variations, congenital and acquired pathologies of the portal venous system are important, especially when planning liver surgery and percutaneous interventional procedures. The portal venous system pathologies can be congenital such as agenesis of portal vein (PV) or can be involved by other hepatic disorders such as cirrhosis and malignancies. In this article, we present normal anatomy, variations, and acquired pathologies involving the portal venous system as seen on computed tomography (CT) and magnetic resonance imaging (MRI).
MeSH term(s)	Female ; Humans ; Liver Diseases/diagnostic imaging ; Magnetic Resonance Imaging/methods ; Male ; Portal Vein/abnormalities ; Portal Vein/anatomy & histology ; Portal Vein/diagnostic imaging ; Tomography, X-Ray Computed/methods
Language	English
Publishing date	2016-10-11
Publishing country	Turkey
Document type	Journal Article ; Review
ZDB-ID	2184145-7
ISSN	1305-3612 ; 1305-3825
ISSN (online)	1305-3612
ISSN	1305-3825
DOI	10.5152/dir.2016.16012
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Article ; Online: Current practices of craniospinal irradiation techniques in Turkey: a comprehensive dosimetric analysis.

Şenkesen, Öznur / Tezcanlı, Evrim / Alkaya, Fadime / İspir, Burçin / Çatlı, Serap / Yeşil, Abdullah / Bezirganoglu, Ebrar / Turan, Sezgi / Köksal, Canan / Güray, Gülay / Hacıislamoğlu, Emel / Durmuş, İsmail Faruk / Çavdar, Şeyma / Aksu, Telat / Çolak, Nurten / Küçükmorkoç, Esra / Doğan, Mustafa / Ercan, Tülay / Karaköse, Fatih /

Alpan, Vildan / Ceylan, Cemile / Poyraz, Gökhan / Nalbant, Nilgül / Kınay, Şeyda / İpek, Servet / Kayalılar, Namık / Tatlı, Hamza / Zhu, Mingyao

Radiation oncology (London, England)

2024 Volume 19, Issue 1, Page(s) 49

Abstract: Objective: This study evaluates various craniospinal irradiation (CSI) techniques used in Turkish centers to understand their advantages, disadvantages and overall effectiveness, with a focus on enhancing dose distribution.: Methods: Anonymized CT ... ...

Abstract	Objective: This study evaluates various craniospinal irradiation (CSI) techniques used in Turkish centers to understand their advantages, disadvantages and overall effectiveness, with a focus on enhancing dose distribution. Methods: Anonymized CT scans of adult and pediatric patients, alongside target volumes and organ-at-risk (OAR) structures, were shared with 25 local radiotherapy centers. They were tasked to develop optimal treatment plans delivering 36 Gy in 20 fractions with 95% PTV coverage, while minimizing OAR exposure. The same CT data was sent to a US proton therapy center for comparison. Various planning systems and treatment techniques (3D conformal RT, IMRT, VMAT, tomotherapy) were utilized. Elekta Proknow software was used to analyze parameters, assess dose distributions, mean doses, conformity index (CI), and homogeneity index (HI) for both target volumes and OARs. Comparisons were made against proton therapy. Results: All techniques consistently achieved excellent PTV coverage (V95 > 98%) for both adult and pediatric patients. Tomotherapy closely approached ideal Dmean doses for all PTVs, while 3D-CRT had higher Dmean for PTV_brain. Tomotherapy excelled in CI and HI for PTVs. IMRT resulted in lower pediatric heart, kidney, parotid, and eye doses, while 3D-CRT achieved the lowest adult lung doses. Tomotherapy approached proton therapy doses for adult kidneys and thyroid, while IMRT excelled for adult heart, kidney, parotid, esophagus, and eyes. Conclusion: Modern radiotherapy techniques offer improved target coverage and OAR protection. However, 3D techniques are continued to be used for CSI. Notably, proton therapy stands out as the most efficient approach, closely followed by Tomotherapy in terms of achieving superior target coverage and OAR protection.
MeSH term(s)	Adult ; Humans ; Child ; Radiotherapy Dosage ; Radiotherapy Planning, Computer-Assisted/methods ; Craniospinal Irradiation/methods ; Turkey ; Radiotherapy, Conformal/methods ; Radiotherapy, Intensity-Modulated/methods
Language	English
Publishing date	2024-04-16
Publishing country	England
Document type	Journal Article
ZDB-ID	2224965-5
ISSN	1748-717X ; 1748-717X
ISSN (online)	1748-717X
ISSN	1748-717X
DOI	10.1186/s13014-024-02435-4
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Article ; Online: Comparison of clinicopathological features and treatments between pre- and postmenopausal female breast cancer patients – a retrospective study

Servet Kocaöz / Birol Korukluoğlu / Ömer Parlak / Hayriye Tatlı Doğan / Fazlı Erdoğan

Menopause Review, Vol 18, Iss 2, Pp 68-

2019 Volume 73

Keywords	breast cancer ; hormone receptor ; premenopausal ; postmenopausal ; breast-conserving surgery ; Medicine ; R
Language	English
Publishing date	2019-06-01T00:00:00Z
Publisher	Termedia Publishing House
Document type	Article ; Online
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Article ; Online: Nonhemorrhagic Adrenal Infarction With Magnetic Resonance Imaging Features During Pregnancy.

Guenette, Jeffrey P / Tatli, Servet

Obstetrics and gynecology

2015 Volume 126, Issue 4, Page(s) 775–778

Abstract: Background: Adrenal infarction is an infrequent cause of severe abdominal pain during pregnancy. The magnetic resonance imaging (MRI) features of adrenal infarction have not previously been thoroughly described.: Cases: A 20-year-old woman, gravida 1 ...

Abstract	Background: Adrenal infarction is an infrequent cause of severe abdominal pain during pregnancy. The magnetic resonance imaging (MRI) features of adrenal infarction have not previously been thoroughly described. Cases: A 20-year-old woman, gravida 1 para 0, presented at 27 4/7 weeks of gestation with sudden-onset right upper quadrant and flank pain. A 29-year-old woman, gravida 2 para 1, presented at 17 5/7 weeks of gestation with sudden-onset right abdominal and flank pain and again at 35 5/7 weeks of gestation with sudden-onset severe left flank and upper quadrant pain. In both patients, unilateral adrenal infarction was diagnosed on contrast-enhanced computed tomography after initial nondiagnostic ultrasonography and MRI. Clinical presentation and MRI features of nonhemorrhagic adrenal infarction are described. Conclusion: Nonhemorrhagic adrenal infarction may be an underdiagnosed cause of acute abdominal pain during pregnancy and can be diagnosed with MRI.
MeSH term(s)	Abdominal Pain/etiology ; Adrenal Glands/blood supply ; Adult ; Female ; Humans ; Infarction/complications ; Infarction/diagnosis ; Magnetic Resonance Imaging ; Pregnancy ; Pregnancy Complications/diagnosis ; Young Adult
Language	English
Publishing date	2015-05-29
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	207330-4
ISSN	1873-233X ; 0029-7844
ISSN (online)	1873-233X
ISSN	0029-7844
DOI	10.1097/AOG.0000000000000884
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Article ; Online: The use of cryoablation in treating liver tumors.

Aghayev, Ayaz / Tatli, Servet

Expert review of medical devices

2014 Volume 11, Issue 1, Page(s) 41–52

Abstract: Percutaneous image-guided tumor ablation techniques have been used as an alternative method for patients with unresectable liver tumors. Although all techniques avoid morbidity and mortality of major surgery and have advantage of preserving non-tumoral ... ...

Abstract	Percutaneous image-guided tumor ablation techniques have been used as an alternative method for patients with unresectable liver tumors. Although all techniques avoid morbidity and mortality of major surgery and have advantage of preserving non-tumoral liver parenchyma, cryoablation currently is the only percutaneous ablation technique allowing intraprocedural monitoring because of visibility of its ablation effect with computed tomography and MRI. Cryoablation uses extremely low temperatures to induce local tissue necrosis to treat both primary and metastatic liver tumors. This article discusses the principles of liver tumor percutaneous cryoablation, including mechanisms of tissue injury, technique, equipment, image-guidance used, patient selection criteria, clinical outcome and complications as well as current trends and future goals.
MeSH term(s)	Clinical Trials as Topic ; Cryosurgery/adverse effects ; Cryosurgery/instrumentation ; Cryosurgery/methods ; Humans ; Imaging, Three-Dimensional ; Liver Neoplasms/diagnostic imaging ; Liver Neoplasms/surgery ; Patient Selection ; Postoperative Complications/etiology ; Radiography
Language	English
Publishing date	2014-01
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2250857-0
ISSN	1745-2422 ; 1743-4440
ISSN (online)	1745-2422
ISSN	1743-4440
DOI	10.1586/17434440.2014.864551
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Article ; Online: Contrast-enhanced CT and MR imaging of renal vessels.

Tuna, Ibrahim S / Tatli, Servet

Abdominal imaging

2014 Volume 39, Issue 4, Page(s) 875–891

Abstract: In the evaluation of renal vessels, the accepted diagnostic gold standard digital subtraction angiography is now being challenged by state of the art CT and MR imaging. Currently in many centers, cross-sectional imaging modalities are being used as a ... ...

Abstract	In the evaluation of renal vessels, the accepted diagnostic gold standard digital subtraction angiography is now being challenged by state of the art CT and MR imaging. Currently in many centers, cross-sectional imaging modalities are being used as a first line diagnostic tool to evaluate arterial and venous system of the kidneys and conventional angiography has been reserved only for therapeutic intervention. CT and MR imaging display not only the lumen of the vessel as in conventional angiography, but also allow the visualization of the vessel wall, renal parenchyma, collecting system, and other adjacent soft tissue structures. Therefore, CT and MRI have each become a one-stop shop for a thorough evaluation of kidneys. In this pictorial essay, we reviewed normal anatomical variants and wide range of pathologies involving renal arteries and veins with illustrated contrast-enhanced CT and MR imaging samples.
MeSH term(s)	Arteriovenous Malformations/diagnosis ; Contrast Media ; Humans ; Image Enhancement ; Imaging, Three-Dimensional ; Kidney/blood supply ; Kidney/diagnostic imaging ; Kidney/pathology ; Magnetic Resonance Angiography ; Renal Artery/diagnostic imaging ; Renal Artery/injuries ; Renal Artery/pathology ; Tomography, X-Ray Computed ; Vascular Diseases/diagnosis
Chemical Substances	Contrast Media
Language	English
Publishing date	2014-08
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1144553-1
ISSN	1432-0509 ; 0942-8925
ISSN (online)	1432-0509
ISSN	0942-8925
DOI	10.1007/s00261-014-0105-1
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Article ; Online: Acute Nonhemorrhagic Adrenal Infarction in Pregnancy: 10-Year MRI Incidence and Patient Outcomes at a Single Institution.

Glomski, Shahar A / Guenette, Jeffrey P / Landman, Wendy / Tatli, Servet

AJR. American journal of roentgenology

2018 Volume 210, Issue 4, Page(s) 785–791

Abstract: Objective: The purpose of this study was to retrospectively investigate the MRI incidence of nonhemorrhagic adrenal infarction in pregnant women undergoing MRI evaluation of acute abdominal or flank pain, assess the MRI features quantitatively, and ... ...

Abstract	Objective: The purpose of this study was to retrospectively investigate the MRI incidence of nonhemorrhagic adrenal infarction in pregnant women undergoing MRI evaluation of acute abdominal or flank pain, assess the MRI features quantitatively, and report patient outcomes. Materials and methods: All abdominal MRI examinations of pregnant women with acute pain at one institution from May 2005 to April 2015 were reviewed. The adrenals were evaluated for abnormal morphologic and signal intensity characteristics described in the literature characterizing nonhemorrhagic adrenal infarction and were compared with the contralateral adrenal by paired t tests. The findings were correlated with clinical presentation. Patient demographics and outcomes were gathered from the medical record. Results: Findings of nonhemorrhagic adrenal infarction were present in 5 of 379 (1.3%) examinations of four pregnant patients (mean age, 28 years; range, 20.8-33.9 years; mean gestational age, 26 weeks; range, 16-35 weeks). MRI features included lengthening (mean, 39.8 versus 21.2 mm) (p = 0.005) and increased T2 signal intensity (p = 0.001) of the infarcted adrenal with surrounding edema and without T1 signal intensity suggesting hemorrhage. No alternative diagnosis was identified. All patients presented with severe acute abdominal or flank pain on the same side as the MRI findings, tenderness to palpation, and mild leukocytosis. All women delivered healthy infants. Conclusion: Unilateral nonhemorrhagic adrenal infarction was identified in 1.3% of abdominal MRI examinations performed for pregnant women with acute abdominal or flank pain. Knowledge of the MRI characteristics of this entity is important for recognizing it and may prevent further potentially invasive tests, procedures, or missed diagnoses.
MeSH term(s)	Abdominal Pain/diagnostic imaging ; Acute Disease ; Adrenal Gland Diseases/diagnostic imaging ; Adrenal Glands/blood supply ; Adult ; Female ; Flank Pain/diagnostic imaging ; Humans ; Incidence ; Infarction/diagnostic imaging ; Magnetic Resonance Imaging/methods ; Pregnancy ; Pregnancy Complications/diagnostic imaging ; Retrospective Studies
Language	English
Publishing date	2018-02-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	82076-3
ISSN	1546-3141 ; 0361-803X ; 0092-5381
ISSN (online)	1546-3141
ISSN	0361-803X ; 0092-5381
DOI	10.2214/AJR.17.18739
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Article ; Online: MRI in local staging of rectal cancer: an update.

Tapan, Umit / Ozbayrak, Mustafa / Tatlı, Servet

Diagnostic and interventional radiology (Ankara, Turkey)

2014 Volume 20, Issue 5, Page(s) 390–398

Abstract: Preoperative imaging for staging of rectal cancer has become an important aspect of current approach to rectal cancer management, because it helps to select suitable patients for neoadjuvant chemoradiotherapy and determine the appropriate surgical ... ...

Abstract	Preoperative imaging for staging of rectal cancer has become an important aspect of current approach to rectal cancer management, because it helps to select suitable patients for neoadjuvant chemoradiotherapy and determine the appropriate surgical technique. Imaging modalities such as endoscopic ultrasonography, computed tomography, and magnetic resonance imaging (MRI) play an important role in assessing the depth of tumor penetration, lymph node involvement, mesorectal fascia and anal sphincter invasion, and presence of distant metastatic diseases. Currently, there is no consensus on a preferred imaging technique for preoperative staging of rectal cancer. However, high-resolution phased-array MRI is recommended as a standard imaging modality for preoperative local staging of rectal cancer, with excellent soft tissue contrast, multiplanar capability, and absence of ionizing radiation. This review will mainly focus on the role of MRI in preoperative local staging of rectal cancer and discuss recent advancements in MRI technique such as diffusion-weighted imaging and dynamic contrast-enhanced MRI.
MeSH term(s)	Humans ; Magnetic Resonance Imaging/methods ; Neoplasm Staging ; Rectal Neoplasms/pathology ; Rectum/pathology
Language	English
Publishing date	2014-07-08
Publishing country	Turkey
Document type	Journal Article ; Review
ZDB-ID	2184145-7
ISSN	1305-3612 ; 1305-3612
ISSN (online)	1305-3612
ISSN	1305-3612
DOI	10.5152/dir.2014.13265
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Article: Comparison of clinicopathological features and treatments between pre- and postmenopausal female breast cancer patients - a retrospective study.

Kocaöz, Servet / Korukluoğlu, Birol / Parlak, Ömer / Doğan, Hayriye Tatlı / Erdoğan, Fazlı

Przeglad menopauzalny = Menopause review

2019 Volume 18, Issue 2, Page(s) 68–73

Abstract: Introduction: To find out if there are clinical and biological differences in breast cancer characteristics of premenopausal and postmenopausal women. For this reason, we investigated the differences in terms of the clinicopathological features and ... ...

Abstract	Introduction: To find out if there are clinical and biological differences in breast cancer characteristics of premenopausal and postmenopausal women. For this reason, we investigated the differences in terms of the clinicopathological features and treatment methods of premenopausal and postmenopausal breast cancer patients in our study. Material and methods: In this study, the files of 428 patients who were operated due to breast cancer between 1 January 2007 and 31 December 2017 in Ankara Atatürk Training and Research Hospital were examined retrospectively. The age, tumour size, tumour grade, oestrogen receptor, progesterone receptor, HER2 score, Ki-67 proliferation index, perineural invasion, and lymphovascular invasion were investigated. Results: In patients with premenopausal breast cancer, the tumour diameter was larger ( Conclusions: Premenopausal and postmenopausal female breast cancer patients have significant differences in tumour size, tumour grade, axillary lymph node metastasis, hormone receptor status, HER2 expression, and treatment modalities.
Language	English
Publishing date	2019-06-14
Publishing country	Poland
Document type	Journal Article
ZDB-ID	2596140-8
ISSN	2299-0038 ; 1643-8876
ISSN (online)	2299-0038
ISSN	1643-8876
DOI	10.5114/pm.2019.85786
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