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  1. Article ; Online: Delivery of the reduced form of vitamin K

    Toki, Erina / Goto, Shotaro / Setoguchi, Shuichi / Terada, Kazuki / Watase, Daisuke / Yamakawa, Hirofumi / Yamada, Ayano / Koga, Mitsuhisa / Kubota, Kaori / Iwasaki, Katsunori / Karube, Yoshiharu / Matsunaga, Kazuhisa / Takata, Jiro

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 19878

    Abstract: ... Several reports have shown that menaquinone-4 (MK-4, vitamin K ...

    Abstract Mitochondria generate energy through the action of the electron transport chain (ETC) and ATP synthase. Mitochondrial malfunction can lead to various disorders, including neurodegenerative diseases. Several reports have shown that menaquinone-4 (MK-4, vitamin K
    MeSH term(s) Mice ; Animals ; Rotenone/toxicity ; Prodrugs/pharmacology ; Reactive Oxygen Species/metabolism ; Cell Death ; 3T3 Cells
    Chemical Substances Rotenone (03L9OT429T) ; Prodrugs ; Reactive Oxygen Species
    Language English
    Publishing date 2022-11-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-24456-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Research Development on K-Ion Batteries.

    Hosaka, Tomooki / Kubota, Kei / Hameed, A Shahul / Komaba, Shinichi

    Chemical reviews

    2020  Volume 120, Issue 14, Page(s) 6358–6466

    Abstract: ... to complement LIBs. In recent years, K-ion batteries (KIBs) have attracted significant attention as potential ... from any scarce/toxic elements, the low standard electrode potentials of K/K ...

    Abstract Li-ion batteries (LIBs), commercialized in 1991, have the highest energy density among practical secondary batteries and are widely utilized in electronics, electric vehicles, and even stationary energy storage systems. Along with the expansion of their demand and application, concern about the resources of Li and Co is growing. Therefore, secondary batteries composed of earth-abundant elements are desired to complement LIBs. In recent years, K-ion batteries (KIBs) have attracted significant attention as potential alternatives to LIBs. Previous studies have developed positive and negative electrode materials for KIBs and demonstrated several unique advantages of KIBs over LIBs and Na-ion batteries (NIBs). Thus, besides being free from any scarce/toxic elements, the low standard electrode potentials of K/K
    Language English
    Publishing date 2020-01-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207949-5
    ISSN 1520-6890 ; 0009-2665
    ISSN (online) 1520-6890
    ISSN 0009-2665
    DOI 10.1021/acs.chemrev.9b00463
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: P2- and P3-K

    Hironaka, Yuya / Kubota, Kei / Komaba, Shinichi

    Chemical communications (Cambridge, England)

    2017  Volume 53, Issue 26, Page(s) 3693–3696

    Abstract: Reversible and topotactic potassium intercalation of P2- and P3-K ...

    Abstract Reversible and topotactic potassium intercalation of P2- and P3-K
    Language English
    Publishing date 2017-03-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472881-3
    ISSN 1364-548X ; 1359-7345 ; 0009-241X
    ISSN (online) 1364-548X
    ISSN 1359-7345 ; 0009-241X
    DOI 10.1039/c7cc00806f
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: A vanadium-based oxide-phosphate-pyrophosphate framework as a 4 V electrode material for K-ion batteries.

    Ohara, Mirai / Hameed, A Shahul / Kubota, Kei / Katogi, Akihiro / Chihara, Kuniko / Hosaka, Tomooki / Komaba, Shinichi

    Chemical science

    2021  Volume 12, Issue 37, Page(s) 12383–12390

    Abstract: K-ion batteries (KIBs) are promising for large-scale electrical energy storage owing ... phosphate, K ...

    Abstract K-ion batteries (KIBs) are promising for large-scale electrical energy storage owing to the abundant resources and the electrochemical specificity of potassium. Among the positive electrode materials for KIBs, vanadium-based polyanionic materials are interesting because of their high working voltage and good structural stability which dictates the cycle life. In this study, a potassium vanadium oxide phosphate, K
    Language English
    Publishing date 2021-08-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2559110-1
    ISSN 2041-6539 ; 2041-6520
    ISSN (online) 2041-6539
    ISSN 2041-6520
    DOI 10.1039/d1sc03725k
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Towards K-Ion and Na-Ion Batteries as "Beyond Li-Ion".

    Kubota, Kei / Dahbi, Mouad / Hosaka, Tomooki / Kumakura, Shinichi / Komaba, Shinichi

    Chemical record (New York, N.Y.)

    2018  Volume 18, Issue 4, Page(s) 459–479

    Abstract: ... therefore, motivated to study Na- and K-ion batteries for stationary energy storage system because of much abundant Na ... and K resources and the wide distribution in the world. In this account, we review developments of Na ... and K-ion batteries with mainly introducing our previous and present researches in comparison ...

    Abstract Li-ion battery commercialized by Sony in 1991 has the highest energy-density among practical rechargeable batteries and is widely used in electronic devices, electric vehicles, and stationary energy storage system in the world. Moreover, the battery market is rapidly growing in the world and further fast-growing is expected. With expansion of the demand and applications, price of lithium and cobalt resources is increasing. We are, therefore, motivated to study Na- and K-ion batteries for stationary energy storage system because of much abundant Na and K resources and the wide distribution in the world. In this account, we review developments of Na- and K-ion batteries with mainly introducing our previous and present researches in comparison to that of Li-ion battery.
    Language English
    Publishing date 2018-04
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2044646-9
    ISSN 1528-0691 ; 1527-8999
    ISSN (online) 1528-0691
    ISSN 1527-8999
    DOI 10.1002/tcr.201700057
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Research Development on K-Ion Batteries

    Hosaka, Tomooki / Kubota, Kei / Hameed, A. Shahul / Komaba, Shinichi

    Chemical reviews. 2020 Jan. 15, v. 120, no. 14

    2020  

    Abstract: ... to complement LIBs. In recent years, K-ion batteries (KIBs) have attracted significant attention as potential ... from any scarce/toxic elements, the low standard electrode potentials of K/K⁺ electrodes lead to high operation ... voltages competitive to those observed in LIBs. Moreover, K⁺ ions exhibit faster ionic diffusion ...

    Abstract Li-ion batteries (LIBs), commercialized in 1991, have the highest energy density among practical secondary batteries and are widely utilized in electronics, electric vehicles, and even stationary energy storage systems. Along with the expansion of their demand and application, concern about the resources of Li and Co is growing. Therefore, secondary batteries composed of earth-abundant elements are desired to complement LIBs. In recent years, K-ion batteries (KIBs) have attracted significant attention as potential alternatives to LIBs. Previous studies have developed positive and negative electrode materials for KIBs and demonstrated several unique advantages of KIBs over LIBs and Na-ion batteries (NIBs). Thus, besides being free from any scarce/toxic elements, the low standard electrode potentials of K/K⁺ electrodes lead to high operation voltages competitive to those observed in LIBs. Moreover, K⁺ ions exhibit faster ionic diffusion in electrolytes due to weaker interaction with solvents and anions than that of Li⁺ ions; this is essential to realize high-power KIBs. This review comprehensively covers the studies on electrochemical materials for KIBs, including electrode and electrolyte materials and a discussion on recent achievements and remaining/emerging issues. The review also includes insights into electrode reactions and solid-state ionics and nonaqueous solution chemistry as well as perspectives on the research-based development of KIBs compared to those of LIBs and NIBs.
    Keywords electrochemistry ; electrodes ; electronics ; energy density ; toxicity
    Language English
    Dates of publication 2020-0115
    Size p. 6358-6466.
    Publishing place American Chemical Society
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 207949-5
    ISSN 1520-6890 ; 0009-2665
    ISSN (online) 1520-6890
    ISSN 0009-2665
    DOI 10.1021/acs.chemrev.9b00463
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Canagliflozin Increases Calorie Intake in Type 2 Diabetes Without Changing the Energy Ratio of the Three Macronutrients: CANA-K Study.

    Matsuba, Ikuro / Kanamori, Akira / Takihata, Masahiro / Takai, Masahiko / Maeda, Hajime / Kubota, Akira / Iemitsu, Kotaro / Umezawa, Shinichi / Obana, Mitsuo / Kaneshiro, Mizuki / Kawata, Takehiro / Takuma, Tetsuo / Takeda, Hiroshi / Machimura, Hideo / Mokubo, Atsuko / Motomiya, Tetsuya / Asakura, Taro / Kikuchi, Taisuke / Matsuzawa, Yoko /
    Ito, Shogo / Miyakawa, Masaaki / Terauchi, Yasuo / Tanaka, Yasushi

    Diabetes technology & therapeutics

    2020  Volume 22, Issue 3, Page(s) 228–234

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Aged ; Canagliflozin/pharmacology ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/drug therapy ; Diet Surveys ; Dietary Carbohydrates/blood ; Dietary Fats/blood ; Dietary Proteins/blood ; Energy Intake/drug effects ; Energy Metabolism/drug effects ; Female ; Glycated Hemoglobin A/analysis ; Humans ; Hypoglycemic Agents/therapeutic use ; Insulin/therapeutic use ; Male ; Middle Aged ; Nutrients/blood ; Prospective Studies ; Sodium-Glucose Transporter 2 Inhibitors/pharmacology ; Weight Loss/drug effects
    Chemical Substances Dietary Carbohydrates ; Dietary Fats ; Dietary Proteins ; Glycated Hemoglobin A ; Hypoglycemic Agents ; Insulin ; Sodium-Glucose Transporter 2 Inhibitors ; Canagliflozin (0SAC974Z85)
    Language English
    Publishing date 2020-02-03
    Publishing country United States
    Document type Clinical Trial ; Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 1452816-2
    ISSN 1557-8593 ; 1520-9156
    ISSN (online) 1557-8593
    ISSN 1520-9156
    DOI 10.1089/dia.2019.0372
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A high voltage honeycomb layered cathode framework for rechargeable potassium-ion battery: P2-type K

    Masese, Titus / Yoshii, Kazuki / Kato, Minami / Kubota, Keigo / Huang, Zhen-Dong / Senoh, Hiroshi / Shikano, Masahiro

    Chemical communications (Cambridge, England)

    2019  Volume 55, Issue 7, Page(s) 985–988

    Abstract: The designing of high voltage cathode materials is critical for the advancement of potassium-ion (K ... equivalently written as K2NiCoTeO6) which exhibits the highest voltage on record (beyond 4 V versus K+/K ... layered cathodes for K-ion battery. ...

    Abstract The designing of high voltage cathode materials is critical for the advancement of potassium-ion (K-ion) battery. Herein, we present a new honeycomb framework P2-type K2/3Ni1/3Co1/3Te1/3O2 (or equivalently written as K2NiCoTeO6) which exhibits the highest voltage on record (beyond 4 V versus K+/K) for layered cathode materials. This work will allow for the further development of, particularly, high voltage layered cathodes for K-ion battery.
    Language English
    Publishing date 2019-01-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472881-3
    ISSN 1364-548X ; 1359-7345 ; 0009-241X
    ISSN (online) 1364-548X
    ISSN 1359-7345 ; 0009-241X
    DOI 10.1039/c8cc07239f
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: [Association of the combined estimated 24-h urinary Na/K ratio and body mass index with blood pressure: Cross-sectional data from the KOBE study].

    Nozawa, Miki / Kuwabara, Kazuyo / Kubota, Yoshimi / Nishida, Yoko / Kubo, Sachimi / Hirata, Takumi / Higashiyama, Aya / Hirata, Aya / Hattori, Hiroko / Sata, Mizuki / Kadota, Aya / Sugiyama, Daisuke / Miyamatsu, Naomi / Miyamoto, Yoshihiro / Okamura, Tomonori

    Nihon koshu eisei zasshi] Japanese journal of public health

    2020  Volume 67, Issue 10, Page(s) 722–733

    Abstract: Objective Several studies have suggested that high dietary Na/K ratio and body mass index (BMI ... of the combined estimated 24-h urinary Na/K ratio (24h-u-Na/K) (high or low) and BMI (high or low) with the risk ... cardiovascular diseases or current anti-hypertensive medications. Sex-specific analyses were performed. The 24h-u-Na/K ...

    Abstract Objective Several studies have suggested that high dietary Na/K ratio and body mass index (BMI) increase the prevalence of hypertension. However, there have been a few reports on the combination of these two factors and their relationship with hypertension. This study aimed to examine the association of the combined estimated 24-h urinary Na/K ratio (24h-u-Na/K) (high or low) and BMI (high or low) with the risk of high blood pressure.Method We performed a cross-sectional study involving 1,112 participants (340 men and 772 women) of the Kobe Orthopedic and Biomedical Epidemiological study (KOBE study) who had no cardiovascular diseases or current anti-hypertensive medications. Sex-specific analyses were performed. The 24h-u-Na/K ratio was calculated from an estimation formula using collected spot urine. Participants were divided into four groups based on their 24h-u-Na/K ratio (low or high) and BMI (low or high), with the cutoff points being the median and 25 kg/m
    MeSH term(s) Blood Pressure ; Body Mass Index ; Cross-Sectional Studies ; Diet, Sodium-Restricted ; Female ; Fruit ; Humans ; Hypertension/diagnosis ; Hypertension/etiology ; Hypertension/prevention & control ; Japan ; Male ; Potassium/urine ; Risk Assessment/methods ; Sodium/urine ; Vegetables
    Chemical Substances Sodium (9NEZ333N27) ; Potassium (RWP5GA015D)
    Language Japanese
    Publishing date 2020-12-22
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 45044-3
    ISSN 0546-1766
    ISSN 0546-1766
    DOI 10.11236/jph.67.10_722
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Efficacy of non-vitamin K antagonist oral anticoagulants for Lemierre syndrome.

    Kubota, Masayuki / Daidoji, Hiroaki / Takaya, Nobuhiro / Tokunaga, Kurato / Sonoo, Tomohiro / Nakamura, Kensuke

    The American journal of emergency medicine

    2016  Volume 34, Issue 10, Page(s) 2059.e3–2059.e5

    MeSH term(s) Administration, Oral ; Ampicillin/therapeutic use ; Anti-Bacterial Agents/therapeutic use ; Anticoagulants/therapeutic use ; Bacteremia/complications ; Bacteremia/drug therapy ; Factor Xa Inhibitors/therapeutic use ; Female ; Heparin/therapeutic use ; Humans ; Lemierre Syndrome/complications ; Lemierre Syndrome/drug therapy ; Middle Aged ; Pyridines/therapeutic use ; Streptococcal Infections/complications ; Streptococcal Infections/drug therapy ; Streptococcus pyogenes ; Sulbactam/therapeutic use ; Thiazoles/therapeutic use
    Chemical Substances Anti-Bacterial Agents ; Anticoagulants ; Factor Xa Inhibitors ; Pyridines ; Thiazoles ; sultamicillin (65DT0ML581) ; Ampicillin (7C782967RD) ; Heparin (9005-49-6) ; edoxaban (NDU3J18APO) ; Sulbactam (S4TF6I2330)
    Language English
    Publishing date 2016-10
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2016.03.040
    Database MEDical Literature Analysis and Retrieval System OnLINE

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