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  1. Article: Management of Status Dystonicus Beyond Intensive Care: An Etiology-Specific Approach.

    Ray, Somdattaa / Yadav, Ravi

    Annals of Indian Academy of Neurology

    2023  Volume 26, Issue 3, Page(s) 213–214

    Language English
    Publishing date 2023-05-18
    Publishing country India
    Document type Editorial
    ZDB-ID 2240174-X
    ISSN 1998-3549 ; 0972-2327
    ISSN (online) 1998-3549
    ISSN 0972-2327
    DOI 10.4103/aian.aian_253_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Movement Disorders and Other Neurologic Impairment Associated With Hypomagnesemia: A Systematic Review.

    Ray, Somdattaa / Park, Kye Won

    Neurology. Clinical practice

    2023  Volume 13, Issue 6, Page(s) e200202

    Abstract: Purpose of review: The objective of this study was to explore the clinical spectrum of movement disorders and associated neurologic findings in hypomagnesemia and challenges in diagnosis and treatment.: Recent findings: Sixty patients were identified ...

    Abstract Purpose of review: The objective of this study was to explore the clinical spectrum of movement disorders and associated neurologic findings in hypomagnesemia and challenges in diagnosis and treatment.
    Recent findings: Sixty patients were identified in the literature for analysis. Movement disorders observed were postural tremor (23.3%, n = 14), resting tremor (8.3%, n = 5), intention tremor (10%, n = 6), ataxia involving the trunk (48.3%, n = 29) or limbs (25%, n = 15) and dysarthria (21.7%, n = 13), athetosis (8.3%, n = 5), myoclonus (6.7%, n = 4), and chorea (1.8%, n = 1). Symptoms may be accompanied by downbeat nystagmus, tetany, drowsiness, vertigo, and proximal muscle weakness. Residual deficits were noted in 16 (26.67%) patients. Serum magnesium was 1.3 mg/dL or lower in 53 patients (88.3%). Imaging findings include bilateral cerebellar (20%, n = 11) and vermis hyperintensities (9.09%, n = 5) and normal imaging. Proton pump inhibitors are the commonest etiology.
    Summary: The movement disorders linked with hypomagnesemia can be associated with varied neurologic symptoms. A high degree of suspicion will enable early diagnosis to prevent residual deficits.
    Language English
    Publishing date 2023-10-02
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2645818-4
    ISSN 2163-0933 ; 2163-0402
    ISSN (online) 2163-0933
    ISSN 2163-0402
    DOI 10.1212/CPJ.0000000000200202
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Hypomagnesemia: A Rare Cause of Movement Disorders, Myopathy and Vertical Nystagmus.

    Ray, Somdattaa / Kamath, Vikram Varadaraya / Jadhav, Swati Ramkete / Rajesh, Karalumangala Nagarajaiah

    Movement disorders clinical practice

    2023  Volume 10, Issue 6, Page(s) 1001–1003

    Language English
    Publishing date 2023-04-12
    Publishing country United States
    Document type Case Reports
    ISSN 2330-1619
    ISSN (online) 2330-1619
    DOI 10.1002/mdc3.13735
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  4. Article: Dystonia in Performing Artists: Beyond Focal Hand Dystonia.

    Ray, Somdattaa / Pal, Pramod K

    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques

    2021  Volume 49, Issue 1, Page(s) 29–37

    Abstract: Overuse of specific muscles in perfecting movements in performing arts makes an artist prone to many medical conditions. Musicians' hand dystonia is focal task-specific dystonia (FTSD) of hand among musicians that has been extensively studied. However, ... ...

    Abstract Overuse of specific muscles in perfecting movements in performing arts makes an artist prone to many medical conditions. Musicians' hand dystonia is focal task-specific dystonia (FTSD) of hand among musicians that has been extensively studied. However, embouchure, lower limbs, and laryngeal muscles can also be affected among musicians. Embouchure dystonia (ED) refers to dystonia of the perioral and facial muscles that occurs in musicians while playing embouchure instruments. It is essential to identify ED since the dystonia might become persistent and non-task-specific if the musician continues to play the instrument. Task-specific dystonia of lower limbs among musicians has been exclusively reported among drummers. The diagnosis rests on electromyogram (EMG) of the involved muscles during the task. Singer's dystonia (SD) refers to task-specific laryngeal dystonia that occurs only while singing. The diagnosis of SD is based on laryngeal EMG and spectrographic analysis. Cortical hyperexcitability, loss of inhibition, and aberrant plasticity are central to the pathogenesis in both ED and musicians' hand dystonia. The pathophysiological studies in SD are limited. This review aims to discuss the lesser known dystonias among performing artists - ED, FTSD of lower limb, and SD.
    MeSH term(s) Dystonia ; Dystonic Disorders/diagnosis ; Facial Muscles ; Hand ; Humans ; Music
    Language English
    Publishing date 2021-03-09
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 197622-9
    ISSN 0317-1671
    ISSN 0317-1671
    DOI 10.1017/cjn.2021.41
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1203: Show issues Location:
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  5. Article: Brachial monomelic amyotrophy as an initial manifestation of stiff person syndrome.

    Ray, Somdattaa / Kamath, Vikram / Rajesh, K N

    Journal of neurosciences in rural practice

    2022  Volume 13, Issue 4, Page(s) 778–780

    Abstract: Stiff person syndrome (SPS) is characterized by rigidity of truncal and proximal muscles. The presence of abdominal and paraspinal rigidity is a defining clinical feature of SPS. It is rarely associated with the lower motor neuron (LMN) features. We ... ...

    Abstract Stiff person syndrome (SPS) is characterized by rigidity of truncal and proximal muscles. The presence of abdominal and paraspinal rigidity is a defining clinical feature of SPS. It is rarely associated with the lower motor neuron (LMN) features. We report a patient with SPS whose initial clinical presentation was that of brachial monomelic amyotrophy (BMA). A 24-year-old gentleman presented with a history of the left upper limb wasting and weakness. In addition, he reported stiffness of the lower limbs and abdomen while walking. On examination, patient had left upper limb monomelic amyotrophy and hypertonia, exaggerated deep tendon reflexes in all four limbs. He also had abdominal and paraspinal rigidity. Serum was strongly positive for GAD 65 antibodies suggestive of SPS. Patient showed dramatic improvement to immunomodulation. Patient presented with features of BMA. Symptoms related to SPS were mild. Abdominal rigidity was the clue to the diagnosis. LMN features have been reported previously in stiff person plus syndrome with an atypical course and progressive encephalomyelitis with myoclonus and rigidity, but not in classical SPS.
    Language English
    Publishing date 2022-12-02
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2601242-X
    ISSN 0976-3155 ; 0976-3147
    ISSN (online) 0976-3155
    ISSN 0976-3147
    DOI 10.25259/JNRP-2022-3-24
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  6. Article: Long-Term Outcome of Hemimasticatory Spasm.

    Ray, Somdattaa / Kamble, Nitish / Yadav, Ravi / Pal, Pramod Kumar

    Journal of movement disorders

    2022  Volume 15, Issue 2, Page(s) 146–150

    Abstract: Objective: This study aims to identify the demographic, clinical, and therapeutic characteristics of four patients with hemimasticatory spasm (HMS) seen in our outpatient department over a period of 20 years.: Methods: We performed a retrospective ... ...

    Abstract Objective: This study aims to identify the demographic, clinical, and therapeutic characteristics of four patients with hemimasticatory spasm (HMS) seen in our outpatient department over a period of 20 years.
    Methods: We performed a retrospective chart review of four patients with HMS who visited outpatient services in the Department of Neurology from 2001 to 2020.
    Results: The follow-up for all patients ranged from 2 years to 9 years. Three patients had facial or bucco-oral morphea. Two patients maintained long-term improvements in symptoms after being treated with botulinum toxin for 4-7 years, while one patient reported improvement in symptoms with treatment of carbamazepine that subsequently remitted after pregnancy.
    Conclusion: This report highlights the long-term outcome of HMS in our patients. Our patients reported a significant reduction or complete resolution of symptoms after treatment, and eventually, two patients were asymptomatic while off treatment.
    Language English
    Publishing date 2022-03-16
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 3021788-X
    ISSN 2093-4939 ; 2005-940X
    ISSN (online) 2093-4939
    ISSN 2005-940X
    DOI 10.14802/jmd.21067
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  7. Article: ADCY5-Related Dyskinesia: A Genetic Cause of Early-Onset Chorea-Report of Two Cases and a Novel Mutation.

    Padmanabha, Hansashree / Ray, Somdattaa / Mahale, Rohan / Arunachal, Gautham / Singhi, Pratibha / Mailankody, Pooja / Pavagada, Mathuranath

    Annals of Indian Academy of Neurology

    2021  Volume 24, Issue 5, Page(s) 837–838

    Language English
    Publishing date 2021-03-27
    Publishing country India
    Document type Journal Article
    ZDB-ID 2240174-X
    ISSN 1998-3549 ; 0972-2327
    ISSN (online) 1998-3549
    ISSN 0972-2327
    DOI 10.4103/aian.AIAN_1012_20
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  8. Article: Sleep and other Non-motor Symptoms in Patients with Idiopathic Oromandibular Dystonia and Meige Syndrome: A Questionnaire-based Study.

    Ray, Somdattaa / Kutty, Bindu / Pal, Pramod Kumar / Yadav, Ravi

    Annals of Indian Academy of Neurology

    2021  Volume 24, Issue 3, Page(s) 351–355

    Abstract: Introduction: Non-motor symptoms are an essential cause of comorbidity in generalized and focal dystonia. However, there are few studies on dystonia involving the craniofacial regions.: Methods: We studied non-motor symptoms in patients with ... ...

    Abstract Introduction: Non-motor symptoms are an essential cause of comorbidity in generalized and focal dystonia. However, there are few studies on dystonia involving the craniofacial regions.
    Methods: We studied non-motor symptoms in patients with oromandibular dystonia (OMD) and Meige syndrome using a questionnaire, and validated instruments for depression, anxiety, REM behaviour disorder, restless leg syndrome, sleep quality, excessive daytime sleepiness, and self-esteem. The severity of dystonia and blepharospasm was also studied.
    Results: Nineteen patients with OMD were recruited into the study. Among patients with OMD, depression was seen in 63.6% (
    Conclusion: This study highlights the significant frequency of depression and sleep disturbances in patients with idiopathic OMD and Meige syndrome.
    Language English
    Publishing date 2021-07-01
    Publishing country India
    Document type Journal Article
    ZDB-ID 2240174-X
    ISSN 1998-3549 ; 0972-2327
    ISSN (online) 1998-3549
    ISSN 0972-2327
    DOI 10.4103/aian.AIAN_906_20
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  9. Article ; Online: DNAJC6 mutation causing cranial-onset dystonia with tremor dominant levodopa non-responsive parkinsonism: A novel phenotype.

    Ray, Somdattaa / Padmanabha, Hansashree / Mahale, Rohan / Mailankody, Pooja / Arunachal, Gautham

    Parkinsonism & related disorders

    2021  Volume 89, Page(s) 1–3

    Abstract: DNAJC6 mutation causes two types of phenotypes: slowly progressive parkinsonism with levodopa response and rapidly progressive parkinsonism with additional manifestations like intellectual disability, epilepsy etc. We report a new phenotype wherein an ... ...

    Abstract DNAJC6 mutation causes two types of phenotypes: slowly progressive parkinsonism with levodopa response and rapidly progressive parkinsonism with additional manifestations like intellectual disability, epilepsy etc. We report a new phenotype wherein an adolescent girl developed blepharospasm followed by jaw opening, lingual and cervical dystonia followed by tremors of limbs (rest and action) with rigidity, bradykinesia. The dystonia-parkinsonism phenotype has not been described. She had novel homozygous missense mutation in DNAJC6 gene.
    MeSH term(s) Adolescent ; Blepharospasm/etiology ; Blepharospasm/physiopathology ; Dystonia/etiology ; Dystonia/physiopathology ; Female ; HSP40 Heat-Shock Proteins/genetics ; Humans ; Hypokinesia/etiology ; Hypokinesia/physiopathology ; Jaw/physiopathology ; Mutation, Missense ; Neck/physiopathology ; Parkinsonian Disorders/complications ; Parkinsonian Disorders/genetics ; Parkinsonian Disorders/physiopathology ; Phenotype ; Tongue/physiopathology ; Tremor/etiology ; Tremor/physiopathology
    Chemical Substances DNAJC6 protein, human ; HSP40 Heat-Shock Proteins
    Language English
    Publishing date 2021-06-23
    Publishing country England
    Document type Case Reports ; Letter
    ZDB-ID 1311489-x
    ISSN 1873-5126 ; 1353-8020
    ISSN (online) 1873-5126
    ISSN 1353-8020
    DOI 10.1016/j.parkreldis.2021.06.013
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4553: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 420: Show issues

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  10. Article: Non-Motor Symptoms in Cervical Dystonia: A Review.

    Ray, Somdattaa / Pal, Pramod Kumar / Yadav, Ravi

    Annals of Indian Academy of Neurology

    2020  Volume 23, Issue 4, Page(s) 449–457

    Abstract: Dystonia is a movement disorder characterized by sustained or intermittent muscle contractions causing abnormal, often repetitive movements, postures, or both. Dystonic movements are typically patterned, associated with twisting of body parts, and may ... ...

    Abstract Dystonia is a movement disorder characterized by sustained or intermittent muscle contractions causing abnormal, often repetitive movements, postures, or both. Dystonic movements are typically patterned, associated with twisting of body parts, and may have tremulousness. Dystonia is usually initiated or worsened by voluntary action and associated with overflow muscle activation. Cervical dystonia (CD) is the most prevalent form of dystonia. CD is a condition characterized by cranial muscle overactivity leading to abnormal intermittent or continuous posturing of the head. Non-motor symptoms are comorbidity of dystonia, which significantly hampers the quality of life among these patients. The symptoms can be as a result of the dystonia itself. However, studies have highlighted the involvement of cortical-striatal-thalamocortical circuits in primary dystonia that could be the pathophysiological basis for the non-motor symptoms. The non-motor symptoms that are commonly associated with dystonia are anxiety, depression, restless leg syndrome, excessive daytime sleepiness, cognitive disturbances, and poor sleep. This review attempts to summarize the literature on non-motor symptoms in patients with CD.
    Language English
    Publishing date 2020-07-31
    Publishing country India
    Document type Journal Article
    ZDB-ID 2240174-X
    ISSN 1998-3549 ; 0972-2327
    ISSN (online) 1998-3549
    ISSN 0972-2327
    DOI 10.4103/aian.AIAN_27_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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