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  1. Article ; Online: An external speed control for nanopore reads.

    Schmid, Sonja

    Nature nanotechnology

    2023  Volume 18, Issue 11, Page(s) 1261–1262

    MeSH term(s) Nanopores ; Sequence Analysis, DNA ; High-Throughput Nucleotide Sequencing
    Language English
    Publishing date 2023-08-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2254964-X
    ISSN 1748-3395 ; 1748-3387
    ISSN (online) 1748-3395
    ISSN 1748-3387
    DOI 10.1038/s41565-023-01477-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: An external speed control for nanopore reads

    Schmid, Sonja

    Nature Nanotechnology

    2023  Volume 18, Issue 11

    Abstract: By integrating a 3D nanopositioner with a solid-state nanopore and surface-tethered molecules, precise spatiotemporal control over single DNA strands is achieved, enabling numerous re-reads and raising the signal-to-noise ratio far beyond previous solid- ... ...

    Abstract By integrating a 3D nanopositioner with a solid-state nanopore and surface-tethered molecules, precise spatiotemporal control over single DNA strands is achieved, enabling numerous re-reads and raising the signal-to-noise ratio far beyond previous solid-state nanopore methods.
    Keywords Life Science
    Language English
    Publishing country nl
    Document type Article ; Online
    ZDB-ID 2254964-X
    ISSN 1748-3395 ; 1748-3387
    ISSN (online) 1748-3395
    ISSN 1748-3387
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  3. Book ; Thesis: Functional characterization of core binding factor leukemia subgroups

    Lück, Sonja C.

    2011  

    Author's details Sonja C. Lück
    Language English
    Size VII, 154 Bl. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Ulm, Univ., Diss., 2011
    HBZ-ID HT018324025
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2014 E 917 order for loan Magazin

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  4. Article ; Online: HaMiPla Best Paper Award – Ihre Favoriten in 2022.

    Gose, Daria / Schmid, Sonja

    Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V...

    2023  Volume 55, Issue 6, Page(s) 470–471

    Title translation HaMiPla Best Paper Award - Your Favourites in 2022.
    Language German
    Publishing date 2023-12-07
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 392414-2
    ISSN 1439-3980 ; 0722-1819
    ISSN (online) 1439-3980
    ISSN 0722-1819
    DOI 10.1055/a-2202-6243
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 670: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Book ; Thesis: Untersuchung der Herzfrequenzvariabilität als Ausdruck des autonomen Erregungsniveaus bei kinderpsychiatrischen Patienten mit und ohne ADHD

    Schmid, Sonja Mathilde

    2008  

    Author's details vorgelegt von Sonja Mathilde Schmid
    Subject code 618.92
    Language German
    Size V, 122 S., Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Tübingen, Univ., Diss., 2008
    HBZ-ID HT016144119
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2009 D 1202 order for loan Magazin

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  6. Article ; Online: Chernobyl

    Schmid, Sonja D

    Technology and culture

    2021  Volume 61, Issue 4, Page(s) 1154–1161

    Abstract: HBO's 2019 miniseries Chernobyl has catapulted the world's worst nuclear disaster back into public awareness with stunning cinematography and captivating dramaturgy. For historians of technology, however, its portrayal of Soviet reactor technology, as ... ...

    Abstract HBO's 2019 miniseries Chernobyl has catapulted the world's worst nuclear disaster back into public awareness with stunning cinematography and captivating dramaturgy. For historians of technology, however, its portrayal of Soviet reactor technology, as well as its baffling omission of the disaster mitigation's most successful feat-the construction of a gigantic concrete entombment-present challenges beyond simple claims to authenticity. Are historians doomed to "abandon even the hope of truth and content ourselves instead with stories?" This essay suggests that even inaccurate storytelling can generate genuine passion, and historians can utilize this passion to nurture curiosity and help our students to seek better answers.
    MeSH term(s) Chernobyl Nuclear Accident ; Disasters ; Humans
    Language English
    Publishing date 2021-01-19
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2021131-4
    ISSN 1097-3729 ; 0040-165X
    ISSN (online) 1097-3729
    ISSN 0040-165X
    DOI 10.1353/tech.2020.0115
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: [No title information]

    Gose, Daria / Schmid, Sonja

    Handchirurgie · Mikrochirurgie · Plastische Chirurgie

    2023  Volume 55, Issue 06, Page(s) 470–471

    Language German
    Publishing date 2023-12-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 392414-2
    ISSN 1439-3980 ; 0722-1819
    ISSN (online) 1439-3980
    ISSN 0722-1819
    DOI 10.1055/a-2202-6243
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 670: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: HaMiPla Best Paper Award – Ihre Favoriten in 2021.

    Gose, Daria / Schmid, Sonja

    Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V...

    2022  Volume 54, Issue 6, Page(s) 529

    Title translation HaMiPla Best Paper Award - Your Favourites in 2021.
    MeSH term(s) Humans ; Awards and Prizes ; Publishing
    Language German
    Publishing date 2022-12-13
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 392414-2
    ISSN 1439-3980 ; 0722-1819
    ISSN (online) 1439-3980
    ISSN 0722-1819
    DOI 10.1055/a-1963-9313
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 670: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article: [No title information]

    Gose, Daria / Schmid, Sonja

    Handchirurgie · Mikrochirurgie · Plastische Chirurgie

    2022  Volume 54, Issue 06, Page(s) 529–529

    Language German
    Publishing date 2022-11-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 392414-2
    ISSN 1439-3980 ; 0722-1819
    ISSN (online) 1439-3980
    ISSN 0722-1819
    DOI 10.1055/a-1963-9313
    Database Thieme publisher's database

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 670: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article: Can DyeCycling break the photobleaching limit in single-molecule FRET?

    Vermeer, Benjamin / Schmid, Sonja

    Nano research

    2022  Volume 15, Issue 11, Page(s) 9818–9830

    Abstract: Biomolecular systems, such as proteins, crucially rely on dynamic processes at the nanoscale. Detecting biomolecular nanodynamics is therefore key to obtaining a mechanistic understanding of the energies and molecular driving forces that control ... ...

    Abstract Biomolecular systems, such as proteins, crucially rely on dynamic processes at the nanoscale. Detecting biomolecular nanodynamics is therefore key to obtaining a mechanistic understanding of the energies and molecular driving forces that control biomolecular systems. Single-molecule fluorescence resonance energy transfer (smFRET) is a powerful technique to observe in real-time how a single biomolecule proceeds through its functional cycle involving a sequence of distinct structural states. Currently, this technique is fundamentally limited by irreversible photobleaching, causing the untimely end of the experiment and thus, a narrow temporal bandwidth of ≤ 3 orders of magnitude. Here, we introduce "DyeCycling", a measurement scheme with which we aim to break the photobleaching limit in smFRET. We introduce the concept of spontaneous dye replacement by simulations, and as an experimental proof-of-concept, we demonstrate the intermittent observation of a single biomolecule for one hour with a time resolution of milliseconds. Theoretically, DyeCycling can provide > 100-fold more information per single molecule than conventional smFRET. We discuss the experimental implementation of DyeCycling, its current and fundamental limitations, and specific biological use cases. Given its general simplicity and versatility, DyeCycling has the potential to revolutionize the field of time-resolved smFRET, where it may serve to unravel a wealth of biomolecular dynamics by bridging from milliseconds to the hour range.
    Electronic supplementary material: Supplementary material is available for this article at 10.1007/s12274-022-4420-5 and is accessible for authorized users.
    Language English
    Publishing date 2022-05-13
    Publishing country China
    Document type Journal Article
    ZDB-ID 2442216-2
    ISSN 1998-0000 ; 1998-0124
    ISSN (online) 1998-0000
    ISSN 1998-0124
    DOI 10.1007/s12274-022-4420-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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